Galactosylated chitosan-g-PEI/DNA complexes-loaded poly(organophosphazene) hydrogel as a hepatocyte targeting gene delivery system

Archives of Pharmacal Research

Volumn 33, Issue 4, 2010, Pages 551-556

  Jiang, Hu Lin ^a   Kim, You Kyoung ^a   Lee, Sun Mi ^b   Park, Mi Ran ^b   Kim, Eun Mi ^c   Jin, Yong Mei ^a   Arote, Rohidas ^a   Jeong, Hwan Jeong ^c   Song, Soo Chang ^b   Cho, Myung Haing ^a   Cho, Chong Su ^a  

^a Seoul National University   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Chonbuk National University Medical School   (South Korea)

Author keywords

Cytotoxicity; Galactosylated chitosan g polyethylenimine; Gene therapy; Hepatocyte targeting; Poly(organophosphazene) hydrogel; Transfection efficiency

Indexed keywords

ANTINEOPLASTIC AGENT; CHITOSAN GRAFT POLYETHYLENIMINE TC 99M; DRUG CARRIER; PLASMID DNA; POLY(ORGANOPHOSPHAZENE); UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CYTOTOXICITY; DNA DRUG COMPLEX; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG SYNTHESIS; FEMALE; GENE DELIVERY SYSTEM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; MOUSE; NONHUMAN;

ANIMALS; CELL SURVIVAL; CHITOSAN; DNA; DRUG CARRIERS; FEMALE; GENE TRANSFER TECHNIQUES; HELA CELLS; HEP G2 CELLS; HEPATOCYTES; HUMANS; HYDROGELS; MICE; MICE, INBRED BALB C; ORGANOPHOSPHORUS COMPOUNDS; POLYETHYLENEIMINE; POLYMERS; SOLUBILITY; TRANSFECTION; VISCOSITY;

EID: 77954504897     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-010-0409-9     Document Type: Article

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