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Volumn 181, Issue 12, 2010, Pages 1310-1317

Knocking down Cav1 calcium channels implicated in Th2 cell activation prevents experimental asthma

Author keywords

Allergic asthma; Antisense oligonucleotides; Th2 cells; Voltage dependent calcium channels

Indexed keywords

ALUMINUM POTASSIUM SULFATE; ANTISENSE OLIGODEOXYNUCLEOTIDE; CYTOKINE; DIHYDROPYRIDINE DERIVATIVE; OVALBUMIN; VOLTAGE DEPENDENT ANION CHANNEL 1; VOLTAGE GATED CALCIUM CHANNEL; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CAV1 PROTEIN, MOUSE; CAVEOLIN 1;

EID: 77954500547     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200907-1166OC     Document Type: Article
Times cited : (51)

References (47)
  • 1
    • 40049092917 scopus 로고    scopus 로고
    • Treatment strategies for allergy and asthma
    • Holgate ST, Polosa R. Treatment strategies for allergy and asthma. Nat Rev Immunol 2008;8:218-230.
    • (2008) Nat Rev Immunol , vol.8 , pp. 218-230
    • Holgate, S.T.1    Polosa, R.2
  • 2
    • 40049100163 scopus 로고    scopus 로고
    • Role of GATA-3 in allergic diseases
    • Barnes PJ. Role of GATA-3 in allergic diseases. Curr Mol Med 2008;8:330-334.
    • (2008) Curr Mol Med , vol.8 , pp. 330-334
    • Barnes, P.J.1
  • 4
    • 34548233165 scopus 로고    scopus 로고
    • Calcium signalling in lymphocyte activation and disease
    • DOI 10.1038/nri2152, PII NRI2152
    • Feske S. Calcium signalling in lymphocyte activation and disease. Nat Rev Immunol 2007;7:690-702. (Pubitemid 47327393)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.9 , pp. 690-702
    • Feske, S.1
  • 5
    • 0031205443 scopus 로고    scopus 로고
    • Selective Loss of the Calcium Ion Signaling Pathway in T Cells Maturing Toward a T Helper 2 Phenotype
    • Sloan-Lancaster J, Steinberg TH, Allen PM. Selective loss of the calcium ion signaling pathway in T cells maturing toward a T helper 2 phenotype. J Immunol 1997;159:1160-1168. (Pubitemid 127484091)
    • (1997) Journal of Immunology , vol.159 , Issue.3 , pp. 1160-1168
    • Sloan-Lancaster, J.1    Steinberg, T.H.2    Allen, P.M.3
  • 7
    • 0034131537 scopus 로고    scopus 로고
    • Differential Ca2+ influx, KCa channel activity, and Ca2+ clearance distinguish Th1 and Th2 lymphocytes
    • Fanger CM, Neben AL, Cahalan MD. Differential Ca2+ influx, KCa channel activity, and Ca2+ clearance distinguish Th1 and Th2 lymphocytes. J Immunol 2000;164:1153-1160.
    • (2000) J Immunol , vol.164 , pp. 1153-1160
    • Fanger, C.M.1    Neben, A.L.2    Cahalan, M.D.3
  • 8
    • 40749143565 scopus 로고    scopus 로고
    • Th17 cells exhibit a distinct calcium profile from Th1 and Th2 Cells and have Th1-like motility and NF-AT nuclear localization
    • Weber KS, Miller MJ, Allen PM. Th17 cells exhibit a distinct calcium profile from Th1 and Th2 Cells and have Th1-like motility and NF-AT nuclear localization. J Immunol 2008;180:1442-1450.
    • (2008) J Immunol , vol.180 , pp. 1442-1450
    • Weber, K.S.1    Miller, M.J.2    Allen, P.M.3
  • 9
    • 62749120029 scopus 로고    scopus 로고
    • Signals for the execution of Th2 effector function
    • Fowell DJ. Signals for the execution of Th2 effector function. Cytokine 2009;46:1-6.
    • (2009) Cytokine , vol.46 , pp. 1-6
    • Fowell, D.J.1
  • 10
    • 57849148942 scopus 로고    scopus 로고
    • Calcium signaling in immune cells
    • Vig M, Kinet JP. Calcium signaling in immune cells. Nat Immunol 2009;10:21-27.
    • (2009) Nat Immunol , vol.10 , pp. 21-27
    • Vig, M.1    Kinet, J.P.2
  • 11
    • 15444365824 scopus 로고    scopus 로고
    • Lymphocyte calcium signaling involves dihydropyridine-sensitive L-type calcium channels: Facts and controversies
    • Gomes B, Savignac M, Moreau M, Leclerc C, Lory P, Guery JC, Pelletier L. Lymphocyte calcium signaling involves dihydropyridine-sensitive L-type calcium channels: facts and controversies. Crit Rev Immunol 2004;24:425-448.
    • (2004) Crit Rev Immunol , vol.24 , pp. 425-448
    • Gomes, B.1    Savignac, M.2    Moreau, M.3    Leclerc, C.4    Lory, P.5    Guery, J.C.6    Pelletier, L.7
  • 12
    • 67349260691 scopus 로고    scopus 로고
    • The calcium/NFAT pathway: Role in development and function of regulatory T cells
    • Oh-hora M, Rao A. The calcium/NFAT pathway: role in development and function of regulatory T cells. Microbes Infect 2009;11:612-619.
    • (2009) Microbes Infect , vol.11 , pp. 612-619
    • Oh-hora, M.1    Rao, A.2
  • 13
    • 2442483760 scopus 로고    scopus 로고
    • Non-voltage-gated L-type Ca2+ channels in human T cells: Pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits
    • Stokes L, Gordon J, Grafton G. Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits. J Biol Chem 2004;279:19566-19573.
    • (2004) J Biol Chem , vol.279 , pp. 19566-19573
    • Stokes, L.1    Gordon, J.2    Grafton, G.3
  • 14
    • 20444410417 scopus 로고    scopus 로고
    • Molecular characterization of L-type calcium channel splice variants expressed in human T lymphocytes
    • Kotturi MF, Jefferies WA. Molecular characterization of L-type calcium channel splice variants expressed in human T lymphocytes. Mol Immunol 2005;42:1461-1474.
    • (2005) Mol Immunol , vol.42 , pp. 1461-1474
    • Kotturi, M.F.1    Jefferies, W.A.2
  • 15
    • 33745574052 scopus 로고    scopus 로고
    • Roles of CRAC and Ca(V)-like channels in T cells: More than one gatekeeper?
    • Kotturi MF, Hunt SV, Jefferies WA. Roles of CRAC and Ca(V)-like channels in T cells: more than one gatekeeper? Trends Pharmacol Sci 2006;27:360-367.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 360-367
    • Kotturi, M.F.1    Hunt, S.V.2    Jefferies, W.A.3
  • 19
    • 70449699616 scopus 로고    scopus 로고
    • Defective survival of naive CD8+ T lymphocytes in the absence of the beta3 regulatory subunit of voltage-gated calcium channels
    • Jha MK, Badou A, Meissner M, McRory JE, Freichel M, Flockerzi V, Flavell RA. Defective survival of naive CD8+ T lymphocytes in the absence of the beta3 regulatory subunit of voltage-gated calcium channels. Nat Immunol 2009;10:1275-1282.
    • (2009) Nat Immunol , vol.10 , pp. 1275-1282
    • Jha, M.K.1    Badou, A.2    Meissner, M.3    McRory, J.E.4    Freichel, M.5    Flockerzi, V.6    Flavell, R.A.7
  • 20
    • 11144356168 scopus 로고    scopus 로고
    • Dihydropyridine receptors are selective markers of Th2 cells and can be targeted to prevent Th2-dependent immunopathological disorders
    • Savignac M, Gomes B, Gallard A, Narbonnet S, Moreau M, Leclerc C, Paulet P, Mariame B, Druet P, Saoudi A, et al. Dihydropyridine receptors are selective markers of Th2 cells and can be targeted to prevent Th2-dependent immunopathological disorders. J Immunol 2004;172:5206-5212.
    • (2004) J Immunol , vol.172 , pp. 5206-5212
    • Savignac, M.1    Gomes, B.2    Gallard, A.3    Narbonnet, S.4    Moreau, M.5    Leclerc, C.6    Paulet, P.7    Mariame, B.8    Druet, P.9    Saoudi, A.10
  • 24
    • 0042847271 scopus 로고    scopus 로고
    • Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling
    • Faroudi M, Zaru R, Paulet P, Muller S, Valitutti S. Cutting edge: T lymphocyte activation by repeated immunological synapse formation and intermittent signaling. J Immunol 2003;171:1128-1132.
    • (2003) J Immunol , vol.171 , pp. 1128-1132
    • Faroudi, M.1    Zaru, R.2    Paulet, P.3    Muller, S.4    Valitutti, S.5
  • 26
    • 33750957976 scopus 로고    scopus 로고
    • Atherosclerosis-related molecular alteration of the human CaV1.2 calcium channel alpha1C subunit
    • Tiwari S, Zhang Y, Heller J, Abernethy DR, Soldatov NM. Atherosclerosis-related molecular alteration of the human CaV1.2 calcium channel alpha1C subunit. Proc Natl Acad Sci USA 2006;103:17024-17029.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17024-17029
    • Tiwari, S.1    Zhang, Y.2    Heller, J.3    Abernethy, D.R.4    Soldatov, N.M.5
  • 28
    • 0034944952 scopus 로고    scopus 로고
    • Molecular properties and physiological roles of ion channels in the immune system
    • DOI 10.1023/A:1010958907271
    • Cahalan MD, Wulff H, Chandy KG. Molecular properties and physiological roles of ion channels in the immune system. J Clin Immunol 2001;21:235-252. (Pubitemid 32652595)
    • (2001) Journal of Clinical Immunology , vol.21 , Issue.4 , pp. 235-252
    • Cahalan, M.D.1    Wulff, H.2    Chandy, K.G.3
  • 29
    • 0028180103 scopus 로고
    • The Ca2+/calmodulin-activated, phosphoprotein phosphatase calcineurin is sufficient for positive transcriptional regulation of the mouse IL-4 gene
    • Kubo M, Kincaid RL, Webb DR, Ransom JT. The Ca2+/calmodulin-activated, phosphoprotein phosphatase calcineurin is sufficient for positive transcriptional regulation of the mouse IL-4 gene. Int Immunol 1994;6:179-188.
    • (1994) Int Immunol , vol.6 , pp. 179-188
    • Kubo, M.1    Kincaid, R.L.2    Webb, D.R.3    Ransom, J.T.4
  • 30
    • 56149115514 scopus 로고    scopus 로고
    • Elevating calcium in Th2 cells activates multiple pathways to induce IL-4 transcription and mRNA stabilization
    • Guo L, Urban JF, Zhu J, Paul WE. Elevating calcium in Th2 cells activates multiple pathways to induce IL-4 transcription and mRNA stabilization. J Immunol 2008;181:3984-3993.
    • (2008) J Immunol , vol.181 , pp. 3984-3993
    • Guo, L.1    Urban, J.F.2    Zhu, J.3    Paul, W.E.4
  • 31
    • 0032571244 scopus 로고    scopus 로고
    • Involvement of dihydropyridine-sensitive calcium channels in human dendritic cell function. Competition by HIV-1 TAT
    • DOI 10.1074/jbc.273.13.7205
    • Poggi A, Rubartelli A, Zocchi MR. Involvement of dihydropyridine- sensitive calcium channels in human dendritic cell function. Competition by HIV-1 Tat. J Biol Chem 1998;273:7205-7209. (Pubitemid 28152736)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.13 , pp. 7205-7209
    • Poggi, A.1    Rubartelli, A.2    Zocchi, M.R.3
  • 32
    • 58049219744 scopus 로고    scopus 로고
    • Ryanodine receptor activation by Cav 1.2 is involved in dendritic cell major histocompatibility complex class II surface expression
    • Vukcevic M, Spagnoli GC, Iezzi G, Zorzato F, Treves S. Ryanodine receptor activation by Cav 1.2 is involved in dendritic cell major histocompatibility complex class II surface expression. J Biol Chem 2008;283:34913-34922.
    • (2008) J Biol Chem , vol.283 , pp. 34913-34922
    • Vukcevic, M.1    Spagnoli, G.C.2    Iezzi, G.3    Zorzato, F.4    Treves, S.5
  • 34
    • 0011895490 scopus 로고    scopus 로고
    • Anti-Ig-induced calcium influx in rat B lymphocytes mediated by cGMP through a dihydropyridine-sensitive channel
    • Sadighi Akha AA, Willmott NJ, Brickley K, Dolphin AC, Galione A, Hunt SV. Anti-Ig-induced calcium influx in rat B lymphocytes mediated by cGMP through a dihydropyridine-sensitive channel. J Biol Chem 1996;271:7297-7300.
    • (1996) J Biol Chem , vol.271 , pp. 7297-7300
    • Sadighi Akha, A.A.1    Willmott, N.J.2    Brickley, K.3    Dolphin, A.C.4    Galione, A.5    Hunt, S.V.6
  • 35
    • 0242361286 scopus 로고    scopus 로고
    • A non-voltage-gated calcium channel with L-type characteristics activated by B cell receptor ligation
    • Grafton G, Stokes L, Toellner KM, Gordon J. A non-voltage-gated calcium channel with L-type characteristics activated by B cell receptor ligation. Biochem Pharmacol 2003;66:2001-2009.
    • (2003) Biochem Pharmacol , vol.66 , pp. 2001-2009
    • Grafton, G.1    Stokes, L.2    Toellner, K.M.3    Gordon, J.4
  • 36
    • 0031964024 scopus 로고    scopus 로고
    • Distinct calcium channel isoforms mediate parathyroid hormone and chlorothiazide-stimulated calcium entry in transporting epithelial cells
    • Barry EL, Gesek FA, Yu AS, Lytton J, Friedman PA. Distinct calcium channel isoforms mediate parathyroid hormone and chlorothiazide-stimulated calcium entry in transporting epithelial cells. J Membr Biol 1998;161:55-64.
    • (1998) J Membr Biol , vol.161 , pp. 55-64
    • Barry, E.L.1    Gesek, F.A.2    Yu, A.S.3    Lytton, J.4    Friedman, P.A.5
  • 37
    • 36849031680 scopus 로고    scopus 로고
    • A smooth muscle Cav1.2 calcium channel splice variant underlies hyperpolarized window current and enhanced state-dependent inhibition by nifedipine
    • Liao P, Yu D, Li G, Yong TF, Soon JL, Chua YL, Soong TW. A smooth muscle Cav1.2 calcium channel splice variant underlies hyperpolarized window current and enhanced state-dependent inhibition by nifedipine. J Biol Chem 2007;282:35133-35142.
    • (2007) J Biol Chem , vol.282 , pp. 35133-35142
    • Liao, P.1    Yu, D.2    Li, G.3    Yong, T.F.4    Soon, J.L.5    Chua, Y.L.6    Soong, T.W.7
  • 38
    • 33646592211 scopus 로고    scopus 로고
    • Localization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation
    • Balijepalli RC, Foell JD, Hall DD, Hell JW, Kamp TJ. Localization of cardiac L-type Ca(2+) channels to a caveolar macromolecular signaling complex is required for beta(2)-adrenergic regulation. Proc Natl Acad Sci USA 2006;103:7500-7505.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7500-7505
    • Balijepalli, R.C.1    Foell, J.D.2    Hall, D.D.3    Hell, J.W.4    Kamp, T.J.5
  • 39
    • 66149158456 scopus 로고    scopus 로고
    • Dynamic interactions between L-type voltage sensitive calcium channel (VSCC) Cav1.2 ({alpha}1C) subunits and ahnak in osteoblastic cells
    • Shao Y, Czymmek KJ, Jones PA, Fomin VP, Akanbi K, Duncan RL, Farach-Carson MC. Dynamic interactions between L-type voltage sensitive calcium channel (VSCC) Cav1.2 ({alpha}1C) subunits and ahnak in osteoblastic cells. Am J Physiol Cell Physiol 2009;296:C1076-C1078.
    • (2009) Am J Physiol Cell Physiol , vol.296
    • Shao, Y.1    Czymmek, K.J.2    Jones, P.A.3    Fomin, V.P.4    Akanbi, K.5    Duncan, R.L.6    Farach-Carson, M.C.7
  • 44
    • 69349103591 scopus 로고    scopus 로고
    • Molecular and biophysical mechanisms of Ca2+ sparklets in smooth muscle
    • Santana LF, Navedo MF. Molecular and biophysical mechanisms of Ca2+ sparklets in smooth muscle. J Mol Cell Cardiol 2009;47:436-444.
    • (2009) J Mol Cell Cardiol , vol.47 , pp. 436-444
    • Santana, L.F.1    Navedo, M.F.2
  • 45
    • 40049088465 scopus 로고    scopus 로고
    • Dendritic cells and epithelial cells: Linking innate and adaptive immunity in asthma
    • DOI 10.1038/nri2275, PII NRI2275
    • Hammad H, Lambrecht BN. Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma. Nat Rev Immunol 2008;8:193-204. (Pubitemid 351323293)
    • (2008) Nature Reviews Immunology , vol.8 , Issue.3 , pp. 193-204
    • Hammad, H.1    Lambrecht, B.N.2
  • 46
    • 1642306579 scopus 로고    scopus 로고
    • IL-4-Dependent Th2 Collateral Priming to Inhaled Antigens Independent of Toll-Like Receptor 4 and Myeloid Differentiation Factor 88
    • Eisenbarth SC, Zhadkevich A, Ranney P, Herrick CA, Bottomly K. IL-4-dependent Th2 collateral priming to inhaled antigens independent of Toll-like receptor 4 and myeloid differentiation factor 88. J Immunol 2004;172:4527-4534. (Pubitemid 38375270)
    • (2004) Journal of Immunology , vol.172 , Issue.7 , pp. 4527-4534
    • Eisenbarth, S.C.1    Zhadkevich, A.2    Ranney, P.3    Herrick, C.A.4    Bottomly, K.5


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