Barriers to participation in cancer prevention clinical trials

Acta Oncologica

Volumn 49, Issue 6, 2010, Pages 757-766

  Hall, Michael J ^a   Egleston, Brian ^a   Miller, Suzanne M ^a   Buzaglo, Joanne S ^a   Millard, Jennifer ^a   Ridgway, Caroline ^a   Damjanov, Nevena ^b   Sprandio, John D ^c   Meropol, Neal J ^d  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c Delaware County Regional Cancer Center   (United States)

^d CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER PATIENT; CANCER PREVENTION; CLINICAL PRACTICE; CLINICAL RESEARCH; CLINICAL STUDY; COMPARATIVE STUDY; MEDICAL SPECIALIST; METHODOLOGY; ONCOLOGY; PARTICIPATORY RESEARCH; PRIORITY JOURNAL; RELATIVE; SOCIAL PSYCHOLOGY; UNITED STATES;

ADULT; ATTITUDE OF HEALTH PERSONNEL; CLINICAL TRIALS AS TOPIC; FAMILY; FEMALE; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HUMANS; INTERNAL MEDICINE; MALE; MEDICAL ONCOLOGY; MIDDLE AGED; NEOPLASMS; ODDS RATIO; PATIENT SELECTION; PENNSYLVANIA; PHYSICIANS; PRIMARY PREVENTION;

EID: 77954499591     PISSN: 0284186X     EISSN: 1651226X     Source Type: Journal    
DOI: 10.3109/0284186X.2010.485209     Document Type: Article

References (28)

1. Comis RL, Miller JD, Aldige CR, Krebs L, Stoval E. Public attitudes toward participation in cancer clinical trials. J Clin Oncol 2003;21 : 830-835
2. Ellis PM. Attitudes towards and participation in randomised clinical trials in oncology: A review of the literature. Ann Oncol 2000;11 : 939-945
3. Ellis PM, Butow PN, Simes RJ, Tattersall MH, Dunn SM. Barriers to participation in randomized clinical trials for early breast cancer among Australian cancer specialists. Aust NZ J Surg 1999;69 : 486-491
4. Go RS, Frisby KA, Lee JA, Mathiason MA, Meyer CH, Osnern JC et al. Clinical trial accrual among new cancer patients at a community-based cancer center. Cancer 2006; 106:426-433
5. Goldman DP, Schoenbaum ML, Potosky AL, Weeks JC, Berry SH, Escarce JJ et al. Measuring the incremental cost of clinical cancer research. J Clin Oncol 2001;19: 105-110
6. Klabunde CN, Springer BC, Butler B, White MS, Atkins J. Factors infl uencing enrollment in clinical trials for cancer treatment. South Med J 1999;92 : 1189-1193
7. Lara PN, Jr., Higdon R, Lim N, Kuan K, Tanaka M, Lau DH et al. Prospective evaluation of cancer clinical trial accrual patterns: Identifying potential barriers to enrollment. J Clin Oncol 2001;19:1728-1733 .
8. Lara PN, Jr., Paterniti DA, Chiechi C, Turrell C, Morain C, Horan N et al. Evaluation of factors affecting awareness of and willingness to participate in cancer clinical trials. J Clin Oncol 2005;23:9282-9289
9. Ross S, Grant A, Counsell C, Gillespie W, Russell I, Prescott R. Barriers to participation in randomised controlled trials: A systematic review. J Clin Epidemiol 1999;52 : 1143-1156
10. Siminoff LA, Zhang A, Colabianchi N, Sturm CM, Shen Q. Factors that predict the referral of breast cancer patients onto clinical trials by their surgeons and medical oncologists. J Clin Oncol 2000;18 : 1203-1211
11. Sung NS, Crowley WF, Jr., Genel M, Salber P, Sandy L, Sherwood LM et al. Central challenges facing the national clinical research enterprise. JAMA 2003;289:1278-1287
12. Meropol NJ, Buzgalo JS, Millard JL, Damjanov N, Miller SM, Ridgway C et al. Psychosocial barriers to clinical trial participation as perceived by oncologists and patients. JNCCN 2007;5:753-762 .
13. Miller SM, Diefenbach M. C-SHIP: A cognitive-social health information processing approach to cancer. In: D. Krantz, editor. Perspectives in behavioral medicine. pp. 219 - 244 Mahwah, NJ: Lawrence Erlbaum; 1998.
14. Hosmer DW, Lemeshow S. Applied logistic regression, 2nd ed. New York: John Wiley and Sons, Inc.; 2000.
15. Brant R. Assessing proportionality in the proportional odds model for ordinal logistic regression. Biometrics 1990;46 : 1171-1178
16. Kendall MG, Smith BB. The problem of M rankings. Ann Math Stat 1939;10:275-287
17. Lawson PJ, Flocke SA. Teachable moments for health behavior change: A concept analysis. Patient Educ Couns 2008. doi:10.10016/j.pec.2008.11.002
18. Miller SM, Shoda Y, Hurley K. Applying cognitive-social theory to health-protective behavior: Breast self-examination in cancer screening. Psychol Bull 1996;119 : 70-94.
19. Mandelblatt J, Kaufman E, Sheppard VB, Pomeroy J, Kavanaugh J, Canar J et al. Breast cancer prevention in community clinics: Will low-income Latina patients participate in clinical trials? Prev Med 2005;40:611-618
20. Buchbinder SP, Metch B, Holte SE, Scheer S, Coletti A, Vittinghoff E. Determinants of enrollment in a preventive HIV vaccine trial: Hypothetical versus actual willingness and barriers to participation. J Acquir Immune Defi c Syndr 2004;36:604-612
21. O'Connell JM, Hogg RS, Chan K, Strathdee SA, McLean N, Martindale SL et al. Willingness to participate and enroll in phase 3 preventive HIV-1 vaccine trial. J Acquir Immune Defi c Syndr 2002;31:521-528
22. Starace F, Wagner TM, Luzi AM, Cafaro L, Gallo P, Rezza G. Knowledge and attitudes regarding preventative HIV vaccine clinical trials in Italy: Results of a national survey. AIDS Care 2006;18:66-72.
23. Halpern SD, Metzger DS, Berlin JA, Ubel PA. Who will enroll? Predicting participation in a phase II AIDS vaccine trial. J Acquir Immune Defi c Syndr 2001;27:281-288
24. Chlebowski RT, Sayre J, Frank-Stromborg M, Bulcavage Lillington, L. Current attitudes and practice of American Society of Clinical Oncology-member clinical oncologists regarding cancer prevention an control. J Clin Oncol 1992;10:164-168
25. Ganz PA, Kwan L, Somerfi eld MR, Alberts D, Garber JE, Offi t K et al. The role of prevention in oncology practice: Results from a 2004 survey of American Society of Clinical Oncology members. J Clin Oncol 2006;24:2948-2957
26. U.S. Census Bureau: State and County Quick Facts. Data derived from Population Estimates, 2000 Census of Population and Housing, 1990 Census of Population and Housing, Small Area Income and Poverty Estimates, Country Business Patterns, 1997 Economic Census, Minority- and Women- Owned Business, Building Permits, Consolidated Federal Funds Report, 1997 Census of Governments [Internet]. 02.2005. [Cited 2010 Mar 18]. Available from: http:quickfacts. census.gov/qfd/states/42000.html.
27. Pennsylvania Department of Health. EpiQMS. [Cited 2010 Mar 18]. Available from: http://app2.health.state.pa.us/ epiqms.
28. Commonwealth of Pennsylvania, Department of Health, Bureau of Health Statistics and Research. Number of cancer case by county, age, sex and race, by 23 primary sites. Pennsylvania residents 2003. [Cited 2010 Mar 18]. Available from: http://www.portal.state.pa.us/portal/server.pt/commu nity/health- statistics-and-research/11599.