메뉴 건너뛰기




Volumn 91, Issue 5, 2010, Pages 831-837

Prognostic significance of the BAALC isoform pattern and CEBPA mutations in pediatric acute myeloid leukemia with normal karyotype: A study by the Japanese Childhood AML Cooperative Study Group

Author keywords

BAALC; CEBPA; Normal karyotype; Pediatric AML

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CEBPA; UNCLASSIFIED DRUG; BAALC PROTEIN, HUMAN; CCAAT ENHANCER BINDING PROTEIN; CEBPA PROTEIN, HUMAN; ISOPROTEIN; TUMOR PROTEIN;

EID: 77954497925     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12185-010-0585-x     Document Type: Article
Times cited : (12)

References (37)
  • 1
    • 34547954572 scopus 로고    scopus 로고
    • The incidence and clinical significance of nucleophosmin mutations in childhood AML
    • DOI 10.1182/blood-2007-02-076604
    • P Brown E Mclntyre R Rau S Meshinchi N Lacayo G Dahl, et al. 2007 The incidence and clinical significance of nucleophosmin mutations in childhood AML Blood 110 979 985 10.1182/blood-2007-02-076604 1:CAS:528:DC%2BD2sXos1CqsbY%3D 17440048 (Pubitemid 47267437)
    • (2007) Blood , vol.110 , Issue.3 , pp. 979-985
    • Brown, P.1    McIntyre, E.2    Rau, R.3    Meshinchi, S.4    Lacayo, N.5    Dahl, G.6    Alonzo, T.A.7    Chang, M.8    Arceci, R.J.9    Small, D.10
  • 2
    • 37549071079 scopus 로고    scopus 로고
    • Tandem duplications of MLL and FLT3 are correlated with poor prognosis in pediatric acute myeloid leukemia: A study of the Japanese childhood AML Cooperative Study Group
    • 10.1002/pbc.21318 17763464
    • A Shimada T Taki K Tabuchi T Taketani R Hanada A Tawa, et al. 2008 Tandem duplications of MLL and FLT3 are correlated with poor prognosis in pediatric acute myeloid leukemia: a study of the Japanese childhood AML Cooperative Study Group Pediatr Blood Cancer 50 264 269 10.1002/pbc.21318 17763464
    • (2008) Pediatr Blood Cancer , vol.50 , pp. 264-269
    • Shimada, A.1    Taki, T.2    Tabuchi, K.3    Taketani, T.4    Hanada, R.5    Tawa, A.6
  • 4
    • 34249656956 scopus 로고    scopus 로고
    • No nucleophosmin mutations in pediatric acute myeloid leukemia with normal karyotype: A study of the Japanese Childhood AML Cooperative Study Group [4]
    • DOI 10.1038/sj.leu.2404625, PII 2404625
    • A Shimada T Taki C Kubota A Tawa K Horibe M Tsuchida, et al. 2007 No nucleophosmin mutations in pediatric acute myeloid leukemia with normal karyotype: a study of the Japanese Childhood AML Cooperative Study Group Leukemia. 21 1307 10.1038/sj.leu.2404625 1:CAS:528:DC%2BD2sXlsFOiurg%3D 17315018 (Pubitemid 46831822)
    • (2007) Leukemia , vol.21 , Issue.6 , pp. 1307
    • Shimada, A.1    Taki, T.2    Kubota, C.3    Tawa, A.4    Horibe, K.5    Tsuchida, M.6    Hanada, R.7    Tsukimoto, I.8    Hayashi, Y.9
  • 7
    • 33644866304 scopus 로고    scopus 로고
    • BAALC expression and FLT3 internal tandem duplication mutations in acute myeloid leukemia patients with normal cytogenetics: Prognostic implications
    • DOI 10.1200/JCO.2005.01.6253
    • CD Baldus C Thiede S Soucek CD Bloomfield E Thiel G Ehninger, et al. 2006 BAALC expression and FLT3 internal tandem duplication mutations in acute myeloid leukemia patients with normal cytogenetics: prognostic implications J Clin Oncol 24 790 797 10.1200/JCO.2005.01.6253 1:CAS:528:DC%2BD28XitVGitr0%3D 16418499 (Pubitemid 46622046)
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.5 , pp. 790-797
    • Baldus, C.D.1    Thiede, C.2    Soucek, S.3    Bloomfield, C.D.4    Thiel, E.5    Ehninger, G.6
  • 8
    • 13244268335 scopus 로고    scopus 로고
    • Molecular heterogeneity and prognostic biomarkers in adults with acute myeloid leukemia and normal cytogenetics
    • DOI 10.1097/01.moh.0000149608.29685.d1
    • G Marcucci K Mrózek CD Bloomfield 2005 Molecular heterogeneity and prognostic biomarkers in adults with acute myeloid leukemia and normal cytogenetics Curr Opin Hematol 12 68 75 10.1097/01.moh.0000149608.29685.d1 1:CAS:528:DC%2BD2MXotFequw%3D%3D 15604894 (Pubitemid 40192577)
    • (2005) Current Opinion in Hematology , vol.12 , Issue.1 , pp. 68-75
    • Marcucci, G.1    Mrozek, K.2    Bloomfield, C.D.3
  • 9
    • 33846230449 scopus 로고    scopus 로고
    • Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: Are we ready for a prognostically prioritized molecular classification?
    • DOI 10.1182/blood-2006-06-001149
    • K Mrózek G Marcucci P Paschka SP Whitman CD Bloomfield 2007 Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification? Blood 109 431 448 10.1182/blood-2006-06- 001149 16960150 (Pubitemid 46105936)
    • (2007) Blood , vol.109 , Issue.2 , pp. 431-448
    • Mrozek, K.1    Marcucci, G.2    Paschka, P.3    Whitman, S.P.4    Bloomfield, C.D.5
  • 10
    • 34247858967 scopus 로고    scopus 로고
    • Clinical outcome of de novo acute myeloid leukaemia patients with normal cytogenetics is affected by molecular genetic alterations: A concise review
    • DOI 10.1111/j.1365-2141.2007.06566.x
    • CD Baldus K Mrózek G Marcucci CD Bloomfield 2007 Clinical outcome of de novo acute myeloid leukaemia patients with normal cytogenetics is affected by molecular genetic alterations: a concise review Br J Haematol 137 387 400 10.1111/j.1365-2141.2007.06566.x 1:CAS:528:DC%2BD2sXotVOhu7c%3D 17488484 (Pubitemid 46698282)
    • (2007) British Journal of Haematology , vol.137 , Issue.5 , pp. 387-400
    • Baldus, C.D.1    Mrozek, K.2    Marcucci, G.3    Bloomfield, C.D.4
  • 11
    • 0037082508 scopus 로고    scopus 로고
    • Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein α in myelodysplastic syndromes and acute myeloid leukemias
    • DOI 10.1182/blood.V99.4.1332
    • AF Gombart WK Hofmann S Kawano S Takeuchi U Krug SH Kwok, et al. 2002 Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein in myelodysplastic syndromes and acute myeloid leukemias Blood 99 1332 1340 10.1182/blood.V99.4.1332 1:CAS:528:DC%2BD38XhtlWqtro%3D 11830484 (Pubitemid 34547089)
    • (2002) Blood , vol.99 , Issue.4 , pp. 1332-1340
    • Gombart, A.F.1    Hofmann, W.-K.2    Kawano, S.3    Takeuchi, S.4    Krug, U.5    Kwok, S.H.6    Larsen, R.J.7    Asou, H.8    Miller, C.W.9    Hoelzer, D.10    Phillip Koeffler, H.11
  • 12
    • 0037108111 scopus 로고    scopus 로고
    • Favorable prognostic significance of CEBPA mutations in patients with de novo acute myeloid leukemia: A study from the Acute Leukemia French Association
    • 10.1182/blood-2002-03-0990 1:CAS:528:DC%2BD38XotVGhsLg%3D 12351377
    • C Preudhomme C Sagot N Boissel JM Cayuela I Tigaud S de Botton, et al. 2002 Favorable prognostic significance of CEBPA mutations in patients with de novo acute myeloid leukemia: a study from the Acute Leukemia French Association Blood 100 2717 2723 10.1182/blood-2002-03-0990 1:CAS:528:DC%2BD38XotVGhsLg%3D 12351377
    • (2002) Blood , vol.100 , pp. 2717-2723
    • Preudhomme, C.1    Sagot, C.2    Boissel, N.3    Cayuela, J.M.4    Tigaud, I.5    De Botton, S.6
  • 13
    • 1442356729 scopus 로고    scopus 로고
    • CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: Prognostic relevance and analysis of cooperating mutations
    • DOI 10.1200/JCO.2004.06.060
    • S Fröhling RF Schlenk I Stolze J Bihlmayr A Benner S Kreitmeier, et al. 2004 CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: prognostic relevance and analysis of cooperating mutations J Clin Oncol 22 624 633 10.1200/JCO.2004.06.060 14726504 (Pubitemid 41095065)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.4 , pp. 624-633
    • Frohling, S.1    Schlenk, R.F.2    Stolze, I.3    Bihlmayr, J.4    Benner, A.5    Kreitmeier, S.6    Tobis, K.7    Dohner, H.8    Dohner, K.9
  • 14
    • 33750087521 scopus 로고    scopus 로고
    • The MLL partial tandem duplication in acute myeloid leukaemia
    • DOI 10.1111/j.1365-2141.2006.06301.x
    • J Basecke JT Whelan F Griesinger FE Bertrand 2006 The MLL partial tandem duplication in acute myeloid leukaemia Br J Haematol 135 438 449 10.1111/j.1365-2141.2006.06301.x 16965385 (Pubitemid 44583410)
    • (2006) British Journal of Haematology , vol.135 , Issue.4 , pp. 438-449
    • Basecke, J.1    Whelan, J.T.2    Griesinger, F.3    Bertrand, F.E.4
  • 16
    • 33644830601 scopus 로고    scopus 로고
    • Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: A Cancer and Leukemia Group B study
    • 10.1200/JCO.2005.03.6137 1:CAS:528:DC%2BD28Xnt1yntg%3D%3D 16275934
    • G Marcucci CD Baldus AS Ruppert MD Radmacher K Mrózek SP Whitman, et al. 2005 Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: a Cancer and Leukemia Group B study J Clin Oncol 23 9234 9242 10.1200/JCO.2005.03.6137 1:CAS:528:DC%2BD28Xnt1yntg%3D%3D 16275934
    • (2005) J Clin Oncol , vol.23 , pp. 9234-9242
    • Marcucci, G.1    Baldus, C.D.2    Ruppert, A.S.3    Radmacher, M.D.4    Mrózek, K.5    Whitman, S.P.6
  • 18
    • 33745746801 scopus 로고    scopus 로고
    • The prognostic value of P-glycoprotein (ABCB) and breast cancer resistance protein (ABCG2) in adults with de novo acute myeloid leukemia with normal karyotype
    • 1:CAS:528:DC%2BD28XntF2jtb4%3D 16704962
    • D Damiani M Tiribelli E Calistri A Geromin A Chiarvesio A Michelutti, et al. 2006 The prognostic value of P-glycoprotein (ABCB) and breast cancer resistance protein (ABCG2) in adults with de novo acute myeloid leukemia with normal karyotype Haematologica 91 825 828 1:CAS:528:DC%2BD28XntF2jtb4%3D 16704962
    • (2006) Haematologica , vol.91 , pp. 825-828
    • Damiani, D.1    Tiribelli, M.2    Calistri, E.3    Geromin, A.4    Chiarvesio, A.5    Michelutti, A.6
  • 19
    • 33845263501 scopus 로고    scopus 로고
    • High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics
    • DOI 10.1182/blood-2006-04-014845
    • M Heuser G Beutel J Krauter K Döhner N von Neuhoff B Schlegelberger, et al. 2006 High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics Blood 108 3898 3905 10.1182/blood-2006-04-014845 1:CAS:528:DC%2BD28Xht1Kgs7rM 16912223 (Pubitemid 44864574)
    • (2006) Blood , vol.108 , Issue.12 , pp. 3898-3905
    • Heuser, M.1    Beutel, G.2    Krauter, J.3    Dohner, K.4    Von Neuhoff, N.5    Schlegelberger, B.6    Ganser, A.7
  • 22
    • 33748806802 scopus 로고    scopus 로고
    • N-terminally truncated WT1 protein with oncogenic properties overexpressed in leukemia
    • DOI 10.1074/jbc.M512391200
    • A Hossain M Nixon MT Kuo GF Saunders 2006 N-terminally truncated WT1 protein with oncogenic properties overexpressed in Leukemia J Biol Chem 281 28122 28130 10.1074/jbc.M512391200 1:CAS:528:DC%2BD28XpsFOrurY%3D 16698800 (Pubitemid 44414526)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.38 , pp. 28122-28130
    • Hossain, A.1    Nixon, M.2    Kuo, M.T.3    Saunders, G.F.4
  • 23
    • 0035525767 scopus 로고    scopus 로고
    • Prognostic significance of minimal residual disease and PML/RARa isoform type: Long-term follow-up in acute promyelocytic leukemia
    • 10.1182/blood.V98.9.2651 1:CAS:528:DC%2BD3MXotVegsL4%3D 11675334
    • JG Jurcic SD Nimer DA Scheinberg T DeBlasio RP Warrell Jr WH Miller Jr, et al. 2001 Prognostic significance of minimal residual disease and PML/RARa isoform type: long-term follow-up in acute promyelocytic leukemia Blood 98 2651 2656 10.1182/blood.V98.9.2651 1:CAS:528:DC%2BD3MXotVegsL4%3D 11675334
    • (2001) Blood , vol.98 , pp. 2651-2656
    • Jurcic, J.G.1    Nimer, S.D.2    Scheinberg, D.A.3    Deblasio, T.4    Warrell Jr., R.P.5    Miller Jr., W.H.6
  • 24
    • 0037082455 scopus 로고    scopus 로고
    • High frequency of Ikaros isoform 6 expression in acute myelomonocytic and monocytic leukemias: Implications for up-regulation of the antiapoptotic protein Bcl-XL in leukemogenesis
    • DOI 10.1182/blood.V99.4.1350
    • T Yagi S Hibi M Takanashi G Kano Y Tabata T Imamura, et al. 2002 High frequency of Ikaros isoform 6 expression in acute myelomonocytic and monocytic leukemias: implications for up-regulation of the antiapoptotic protein Bcl-XL in leukemogenesis Blood 99 1350 1354 10.1182/blood.V99.4.1350 1:CAS:528: DC%2BD38XhtlWqtrg%3D 11830486 (Pubitemid 34547091)
    • (2002) Blood , vol.99 , Issue.4 , pp. 1350-1355
    • Yagi, T.1    Hibi, S.2    Takanashi, M.3    Kano, G.4    Tabata, Y.5    Imamura, T.6    Inaba, T.7    Morimoto, A.8    Todo, S.9    Imashuku, S.10
  • 26
    • 33344471932 scopus 로고    scopus 로고
    • KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): A study of the Japanese ChildhoodAMLCooperative Study Group
    • DOI 10.1182/blood-2005-08-3408
    • A Shimada T Taki K Tabuchi A Tawa K Horibe M Tsuchida, et al. 2006 KIT mutations, and not FLT3 internal tandem duplication, are strongly associated with a poor prognosis in pediatric acute myeloid leukemia with t(8;21): a study of the Japanese Childhood AML Cooperative Study Group Blood 107 1806 1809 10.1182/blood-2005-08-3408 1:CAS:528:DC%2BD28XitFyht7c%3D 16291592 (Pubitemid 43289357)
    • (2006) Blood , vol.107 , Issue.5 , pp. 1806-1809
    • Shimada, A.1    Taki, T.2    Tabuchi, K.3    Tawa, A.4    Horibe, K.5    Tsuchida, M.6    Hanada, R.7    Tsukimoto, I.8    Hayashi, Y.9
  • 27
    • 69849101233 scopus 로고    scopus 로고
    • Risk-stratified therapy and the intensive use of cytarabine improves the outcome in childhood acute myeloid leukemia: The AML99 trial from the Japanese Childhood AML Cooperative Study Group
    • 10.1200/JCO.2008.18.7948 1:CAS:528:DC%2BD1MXhtFCgsbvP 19620491
    • I Tsukimoto A Tawa K Horibe K Tabuchi H Kigasawa M Tsuchida, et al. 2009 Risk-stratified therapy and the intensive use of cytarabine improves the outcome in childhood acute myeloid leukemia: the AML99 trial from the Japanese Childhood AML Cooperative Study Group J Clin Oncol 27 4007 4013 10.1200/JCO.2008.18.7948 1:CAS:528:DC%2BD1MXhtFCgsbvP 19620491
    • (2009) J Clin Oncol , vol.27 , pp. 4007-4013
    • Tsukimoto, I.1    Tawa, A.2    Horibe, K.3    Tabuchi, K.4    Kigasawa, H.5    Tsuchida, M.6
  • 28
    • 0035093813 scopus 로고    scopus 로고
    • Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia
    • DOI 10.1038/85820
    • T Pabst BU Mueller P Zhang HS Radomska S Narravula S Schnittger, et al. 2001 Dominant-negative mutations of CEBPA, encoding CCAT/enhancer binding protein-alpha (C/EBPalpha), in acute myeloid leukemia Nat Genet 27 263 270 10.1038/85820 1:CAS:528:DC%2BD3MXhslOjs78%3D 11242107 (Pubitemid 32201846)
    • (2001) Nature Genetics , vol.27 , Issue.3 , pp. 263-270
    • Pabst, T.1    Mueller, B.U.2    Zhang, P.3    Radomska, H.S.4    Narravula, S.5    Schnittger, S.6    Behre, G.7    Hiddemann, W.8    Tenen, D.G.9
  • 29
    • 77954543338 scopus 로고    scopus 로고
    • Molecular monitoring of BAALC expression in patients with CD34-positive acute leukemia
    • Najima Y, Ohashi K, Kawamura M, Onozuka Y, Yamaguchi T, Akiyama H, et al. Molecular monitoring of BAALC expression in patients with CD34-positive acute leukemia. Int J Hematol. 2010. doi: 10.1007/s12185-010-0550-8.
    • (2010) Int J Hematol
    • Najima, Y.1    Ohashi, K.2    Kawamura, M.3    Onozuka, Y.4    Yamaguchi, T.5    Akiyama, H.6
  • 31
  • 32
    • 13244252410 scopus 로고    scopus 로고
    • BAALC 1-6-8 protein is targeted to postsynaptic lipid rafts by its N-terminal myristoylation and palmitoylation, and interacts with α, but not β, subunit of Ca2+/calmodulin-dependent protein kinase II
    • DOI 10.1111/j.1471-4159.2004.02902.x
    • X Wang QB Tian A Okano H Sakagami IS Moon H Kondo, et al. 2005 BAALC 1-6-8 protein is targeted to postsynaptic lipid rafts by its N-terminal myristoylation and palmitoylation, and interacts with alpha, but not beta, subunit of Ca/calmodulin-dependent protein kinase II J Neurochem 92 647 659 10.1111/j.1471-4159.2004.02902.x 1:CAS:528:DC%2BD2MXht12msb0%3D 15659234 (Pubitemid 40189467)
    • (2005) Journal of Neurochemistry , vol.92 , Issue.3 , pp. 647-659
    • Wang, X.1    Tian, Q.-B.2    Okano, A.3    Sakagami, H.4    Moon, I.S.5    Kondo, H.6    Endo, S.7    Suzuki, T.8
  • 33
    • 0142195934 scopus 로고    scopus 로고
    • BAALC, a novel marker of human hematopoietic progenitor cells
    • 1:CAS:528:DC%2BD3sXosVyktro%3D 14585369
    • CD Baldus SM Tanner DF Kusewitt S Liyanarachchi C Choi MA Caligiuri, et al. 2003 BAALC, a novel marker of human hematopoietic progenitor cells Exp Hematol 31 1051 1056 1:CAS:528:DC%2BD3sXosVyktro%3D 14585369
    • (2003) Exp Hematol , vol.31 , pp. 1051-1056
    • Baldus, C.D.1    Tanner, S.M.2    Kusewitt, D.F.3    Liyanarachchi, S.4    Choi, C.5    Caligiuri, M.A.6
  • 34
    • 33646575624 scopus 로고    scopus 로고
    • Implications of NRAS mutations in AML: A study of 2502 patients
    • DOI 10.1182/blood-2005-08-3522
    • U Bacher T Haferlach C Schoch W Kern S Schnittger 2006 Implications of NRAS mutations in AML: a study of 2502 patients Blood 107 3847 3853 10.1182/blood-2005-08-3522 1:CAS:528:DC%2BD28XkvFWhtbg%3D 16434492 (Pubitemid 43726786)
    • (2006) Blood , vol.107 , Issue.10 , pp. 3847-3853
    • Bacher, U.1    Haferlach, T.2    Schoch, C.3    Kern, W.4    Schnittger, S.5
  • 35
    • 15044358998 scopus 로고    scopus 로고
    • CEBPA point mutations in hematological malignancies
    • DOI 10.1038/sj.leu.2403614
    • H Leroy C Roumier P Huyghe V Biggio P Fenaux C Preudhomme 2005 CEBPA point mutations in hematological malignancies Leukemia 19 329 334 10.1038/sj.leu.2403614 1:CAS:528:DC%2BD2MXhsFOru78%3D 15674366 (Pubitemid 40409478)
    • (2005) Leukemia , vol.19 , Issue.3 , pp. 329-334
    • Leroy, H.1    Roumier, C.2    Huyghe, P.3    Biggio, V.4    Fenaux, P.5    Preudhomme, C.6
  • 37
    • 63849241865 scopus 로고    scopus 로고
    • Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome
    • 10.1182/blood-2008-09-179895 1:CAS:528:DC%2BD1MXktFWnt74%3D 19171880
    • BJ Wouters B Löwenberg CA Erpelinck-Verschueren WL van Putten PJ Valk R Delwel 2009 Double CEBPA mutations, but not single CEBPA mutations, define a subgroup of acute myeloid leukemia with a distinctive gene expression profile that is uniquely associated with a favorable outcome Blood 113 3088 3091 10.1182/blood-2008-09-179895 1:CAS:528:DC%2BD1MXktFWnt74%3D 19171880
    • (2009) Blood , vol.113 , pp. 3088-3091
    • Wouters, B.J.1    Löwenberg, B.2    Erpelinck-Verschueren, C.A.3    Van Putten, W.L.4    Valk, P.J.5    Delwel, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.