Effect of ankaferd blood stopper on hemostasis and histopathological score in experimental liver injury

Bratislava Medical Journal

Volumn 111, Issue 4, 2010, Pages 183-188

  Kalayci, Mustafa Uygar ^a,b   Soylu, Aliye ^a,b   Eroglu, Hasan Erol ^b,c   Kubilay, Dilek ^b,d   Sancak, Banu ^b,e   Ugurluoglu, Ceyhan ^b,f   Ercin, Ugur ^b,e   Koca, Yavuz ^b,c   Karatepe, Oguzhan ^a,b  

^a OKMEYDANI TRAINING AND RESEARCH HOSPITAL   (Turkey)

^b BAKIRKOY DR SADI KONUK TRAINING AND RESEARCH HOSPITAL   (Turkey)

^c SULEYMAN DEMIREL UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^d Dr Abdurrahman Yurtaslan Oncology Training and Research Hospital   (Turkey)

^e GAZI UNIVERSITY   (Turkey)

^f Dr Faruk Sukan Obstetrics and Children's Hospital   (Turkey)

Author keywords

Adhesion; Ankaferd; Hemostasis; Histopathological score; Liver injury

Indexed keywords

ANKAFERD BLOOD STOPPER; HEMOSTATIC AGENT; PLANT EXTRACT;

ANIMAL; ARTICLE; BLEEDING; DRUG EFFECT; HEMOSTASIS; INJURY; LIVER; PATHOLOGY; RAT;

ANIMALS; HEMORRHAGE; HEMOSTASIS; HEMOSTATICS; LIVER; PLANT EXTRACTS; RATS;

EID: 77954494425     PISSN: 00069248     EISSN: 13360345     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Velmahos GC, Toutouzas K, Radin R, Chan L, Rhee P, Tillou A, De,etriades D. High success with nonoperative management of blunt hepatic trauma: the liver is a study organ. Arch Surg 2003; 138 (5): 475-481.
2. Berrevoet F, de Hemptinne B. Clinical application of topical sealants in liver surgery: does it work? Acta Chir Belg 2007; 107 (5): 504-507.
3. Tsugawa K, Koyanagi N, Hashizume M, Ayukawa K, Wada H, Tomikawa M, Yeyama T, Sugimachi K. Anatomic resection for severe blunt liver trauma in 100 patients: significant differences young and elderly. World J Surg 2002; 26 (5): 544-549.
4. Polanco P, Leon S, Pineda J, Puyana JC, Ochoa JB, Alarcon L, Harbrecht BG, Geller D, Peitzman AB. Hepatic resection in the ma nagement of complex injury to the liver. J Trauma 2008; 65: 1264-1269.
5. Berrevoet F, de Hemptinne B. Use of topical hemostatic agents during liver resection. Dig Surg 2007; 24 (4): 288-293.
6. Seyednejad H, Imani M, Jamieson T, Seifalian AM. Topical haemostatic agents. Br J Surg 2008; 95 (10): 1197-1225.
7. Jamall IS, Finelli VN, Que Hee SS. A simple method to determine nanogram levels of 4-hydroxyproline in biological tissues. Anal Bio-chem 1981; 112 (1): 70-75.
8. Bothin C, Okada M, Midtvedt T, Perbeck L. The intestinal flora influences adhesion formation around surgical anastomoses. Br J Surg 2001; 88 (1): 143-145.
9. Tovar MC, Sanchez -Valverde MA, Agut A, Laredo FG, Murciano J. Comparative study of air coagulation, fibrin sealant, and suture in experimental liver injury. Eur J Surg 1998; 164 (1): 57-63.
10. Kraus TW, Mehrabi A, Schemmer P, Kashfi A, Berberat P, Buchler MW. Scientific evidence for application of topical hemostats, tissue glues, and sealants in hepatobiliary surgery. J Amer Coll Surg 2005; 200(3): 418^27.
11. Uranüs S, Mischinger HJ, Pfeifer J, Kronberger L Jr, Rabl H, Werkgartner G, Steindorfer P, Kraft-Kirz J. Hemostatic methods for the management of spleen and liver injuries. World J Surg 1996; 20 (8): 1107-1111.
12. Samudrala S. Topical hemostatic agents in surgery: a surgeon's perspective. AORN J 2008; 88 (3): S2-11.
13. Kitamura K, Yasuoka R, Ohara M, Shimotsuma M, Hagiwara A, Yamane T, Yamaguchi T, Takahashi T. How safe are the xenogeneic hemostats - report of a case of severe systemic allergic reaction. Surg Today 1995; 25 (5): 433-435.
14. Gao HW, Lin CK, Yu CP, Yu MS, Chen A. Oxidized cellulose (SurgicelTM) granuloma mimicking a primary ovarian tumor. Int J Gynecol Pathol 2002; 21 (4): 422-423.
15. Bernabeu E, Castella M, Barriuso C, Mulet J. Acute limb ischemia due to embolization of biological glue after repair of type A aortic dissection. Interact Cardiovasc Thorac Surg 2005; 4 (4): 329-331.
16. Klimo P Jr, Khalil A, Slotkin JR, Smith ER, Scott RM, Goumnerova LC. Wound complications associated with the use of bovine serum albumin-glutaraldehyde surgical adhesive in pediatric patients. Neurosurgery 2007; 60 (4 Suppl 2): 305-309.
17. Pusateri AE, Modrow HE, Harris RA, Holcomb JB, Hess JR, Mosebar RH, Reid TJ, Nelson JH, Goodwin CW Jr, Fitzpatrick GM, McManus AT, Zolock DT, Sondeen JL, Cornum RL, Martinez RS. Advanced hemostatic dressing development program: animal model selection criteria and results of a study of nine hemostatic dressings in a model of severe large venous hemorrhage and hepatic injury in Swine. J Trauma 2003; 55 (3): 518-526.
18. Wright JK, Kalns J, Wolf EA, Traweek F, Schwarz S, Loeffler CK, Snyder W, Yantis LD Jr, Eggers J. Thermal injury resulting from application of a granular mineral hemostatic agent. J Trauma 2004; 57 (2): 224-230.
19. Goker H, Haznedaroglu IC, Ercetin S, Kirazli S, Akman U, Ozturk Y, Firat HC. Haemostatic actions of the folkloric medicinal plant extract Ankaferd Blood Stopper. J Int Med Res 2008; 36 (1): 163-170.
20. Matsuda H, Ando S Kato T, Morikawa T, Yoshikawa M. Inhibitors from the rhizomes of Alpinia officinarum on production of nitric oxide in lipopolysaccharide-activated macrophages and the structural requirements of diarylheptanoids for the activity. Bioorg Med Chem 2006; 14(1): 138-142.
21. Lee SJ, Umano K, Shibamoto T, Lee KG. Identification of volatile components in basil (Ocimum basilicum L.) and thyme leaves (Thymus vulgarisL.) and their antioxidant properties. Food Chem 2005; 91: 131-137.
22. Testai L, Chericoni S, Calderone V, Nencioni G, Nieri P, Morelli I, Martinotti E. Cardiovascular effects of Urtica dioica L. (Urticaceae) roots extracts: in vitro and in vivo pharmacological studies. J Ethnopharmacol 2002; 81 (1): 105-109.
23. Sheela ML, Ramakrishna MK, Salimath BP. Angiogenic and proliferative effects of the cytokine VEGF in Ehrlich ascites tumor cells is inhibited by Glycyrrhiza glabra. Int Immunopharmacol 2006; 6 (3): 494-498.
24. Canan UA, Caliskan U, Haznedaroglu IC, Goker H. Haemostatic actions of the folkloric medicinal plant extract Ankaferd Blood Stopper. J Int Med Res 2008; 36 (6): 1447-1449.
25. Cipil HS, Kosar A, Kaya A, Uz B, Haznedaroglu IC, Goker H, Ozdemir O, Koroglu M, Kirazli S, Firat HC. In vivo haemostatic effeet of medicinal plant extract Ankaferd Blood Stopper in Rats pretreated with warfarin. Clin Appl Thromb Hemost 2009; 15 (3): 270-276.
26. Jakob H, Campbell CD, Stemberger A, Wriedt-Lubbe I, Blumel G, Replogle RL. Combined application of heterologous collagens and fibrin glue for liver injuries. J Surg Res 1984; 36 (6): 571-577.
27. Bilgili H, Kosar A, Kurt M, Onal IK, Goker H, Captug O, Shorbagi A, Turgut M, Kekilli M, Kurt OK, Kirazly S, Aksu S, Haznedaroglu IC. Hemostatic efficacy of Ankaferd BloodStopper in a swine bleeding model. Med Princ Pract 2009; 18 (3): 165-169.
28. Huri E, Akgul T, Ayyildiz A, Ustun H, Germiyanoglu C. Hemostatic role of a foMoric medicinal plant extract in a rat partial nephrectomy model: controlle experimental trial. J Urol 2009; 181 (5): 2349-2354.
29. Kurt M, Disibeyaz S, Akdogan M, Sasmaz N, Aksu S, Haznedaroglu IC. Endoscopic application of ankaferd blood stopper as a novel experimental treatment modality for upper gastrointestinal bleeding: a case reort. Am J Gastroenterol 2008; 103 (8): 2156-2158.
30. Kurt M, Kacar S, Onal IK, Akdogan M, Haznedaroglu IC. Ankaferd Blood Stopper as an effective adjunctive haemostatic agent for the management of life threatening arterial bleeding of the digestive tract. Endoscopy 2008; 40 (Suppl 2): E 262.
31. Ibis M, Kurt M, Onal IK, Haznedaroglu IC. Successful manage ment of bleeding due to solitary rectal ulcer via topical application of Ankaferd blood stopper. J Altern Complement Med 2008; 14 (9): 1073-1074.
32. Karakaya K, Ucan HB, Tascilar O, Emre AU, Cakmak GK, Irkorucu O, Ankarali H, Comert M. Evaluation of a new hemostatic agent Ankeferd Blood Stopper in experimental liver laceration. J Invest Surg 2009; 22 (3): 201-206.
33. Kurt M, Disibeyaz S, Akdogan M, Sasmaz N, Aksu S, Haznedaroglu IC. Endoscopic application of ankaferd blood stopper as a novel experimental treatment modality for upper gastrointestibnal bleeding: a case report. Am J Gastroenterol 2008; 103 (8): 2156-2158.
34. Dine S, Ozaslan C, Kuru B, Karaca S, Ustun H, Alagol H, Renda N, Oz M. Methylene blue prevents surgery-induced peritoneal adhesions but impairs the early phase of anastomotic wound healing. Can J Surg 2006; 49 (5): 321-328.
35. Muller V, Brummer D, Ehrhardt W, Henke J, Kissler H, Bauer M, Amann K, Ott R, Hohenberger W. Arterialisation of the portal vein as a model for the induction of hepatic fibrosis: Description of microsurgical models in the rat. Transpl Int 2005; 17 (12): 822-833.