-
1
-
-
0035289536
-
Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke
-
Abdelkarim GE, Gertz K, Harms C, Katchanov J, Dirnagl U, Szabo C, Endres M. Protective effects of PJ34, a novel, potent inhibitor of poly(ADP-ribose) polymerase (PARP) in in vitro and in vivo models of stroke. Int J Mol Med 7: 255-260, 2001.
-
(2001)
Int J Mol Med
, vol.7
, pp. 255-260
-
-
Abdelkarim, G.E.1
Gertz, K.2
Harms, C.3
Katchanov, J.4
Dirnagl, U.5
Szabo, C.6
Endres, M.7
-
2
-
-
27744476223
-
Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia
-
Culmsee C, Zhu C, Landshamer S, Becattini B, Wagner E, Pellechia M, Blomgren K, Plesnila N. Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia. J Neurosci 25: 10262-10272, 2005.
-
(2005)
J Neurosci
, vol.25
, pp. 10262-10272
-
-
Culmsee, C.1
Zhu, C.2
Landshamer, S.3
Becattini, B.4
Wagner, E.5
Pellechia, M.6
Blomgren, K.7
Plesnila, N.8
-
3
-
-
40249097634
-
EXOG, a novel paralog of endonuclease G in higher eukaryotes
-
Cymerman IA, Chung I, Beckmann BM, Bujnicki JM, Meiss G. EXOG, a novel paralog of endonuclease G in higher eukaryotes. Nucleic Acids Res 36: 1369-1379, 2008.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 1369-1379
-
-
Cymerman, I.A.1
Chung, I.2
Beckmann, B.M.3
Bujnicki, J.M.4
Meiss, G.5
-
4
-
-
33745250108
-
EndoG is dispensable in embryogenesis and apoptosis
-
David KK, Sasaki M, Yu SW, Dawson TM, Dawson VL. EndoG is dispensable in embryogenesis and apoptosis. Cell Death Differ 13: 1147-1155, 2006.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1147-1155
-
-
David, K.K.1
Sasaki, M.2
Yu, S.W.3
Dawson, T.M.4
Dawson, V.L.5
-
5
-
-
0033502803
-
Early decrease of apurinic/apyrimidinic endonuclease expression after transient focal cerebral ischemia in mice
-
Fujimura M, Morita-Fujimura Y, Kawase M, Chan PH. Early decrease of apurinic/apyrimidinic endonuclease expression after transient focal cerebral ischemia in mice. J Cereb Blood Flow Metab 19: 495-501, 1999. (Pubitemid 30159811)
-
(1999)
Journal of Cerebral Blood Flow and Metabolism
, vol.19
, Issue.5
, pp. 495-501
-
-
Fujimura, M.1
Morita-Fujimura, Y.2
Kawase, M.3
Chan, P.H.4
-
6
-
-
68549109477
-
Oxidative stress triggers neuronal caspase-independent death: Endonuclease G involvement in programmed cell death-type III
-
Higgins GC, Beart PM, Nagley P. Oxidative stress triggers neuronal caspase-independent death: endonuclease G involvement in programmed cell death-type III. Cell Mol Life Sci 66: 2773-2787, 2009.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 2773-2787
-
-
Higgins, G.C.1
Beart, P.M.2
Nagley, P.3
-
7
-
-
11144334739
-
Generation and characterization of endonuclease G null mice
-
Irvine RA, Adachi N, Shibata DK, Cassell GD, Yu K, Karanjawala ZE, Hsieh CL, Lieber MR. Generation and characterization of endonuclease G null mice. Mol Cell Biol 25: 294-302, 2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 294-302
-
-
Irvine, R.A.1
Adachi, N.2
Shibata, D.K.3
Cassell, G.D.4
Yu, K.5
Karanjawala, Z.E.6
Hsieh, C.L.7
Lieber, M.R.8
-
8
-
-
33646539188
-
Involvement of endonuclease G in nucleosomal DNA fragmentation under sustained endogenous oxidative stress
-
Ishihara Y, Shimamoto N. Involvement of endonuclease G in nucleosomal DNA fragmentation under sustained endogenous oxidative stress. J Biol Chem 281: 6726-6733, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 6726-6733
-
-
Ishihara, Y.1
Shimamoto, N.2
-
9
-
-
23944462470
-
Regulation of the human apoptotic DNase/RNase endonuclease G: Involvement of Hsp70 and ATP
-
Kalinowska M, Garncarz W, Pietrowska M, Garrard WT, Widlak P. Regulation of the human apoptotic DNase/RNase endonuclease G: involvement of Hsp70 and ATP. Apoptosis 10: 821-830, 2005.
-
(2005)
Apoptosis
, vol.10
, pp. 821-830
-
-
Kalinowska, M.1
Garncarz, W.2
Pietrowska, M.3
Garrard, W.T.4
Widlak, P.5
-
10
-
-
63949084979
-
Inhibition of poly(ADP-ribose) polymerase suppresses inflammation and promotes recovery after ischemic injury
-
Kauppinen TM, Suh SW, Berman AE, Hamby AM, Swanson RA. Inhibition of poly(ADP-ribose) polymerase suppresses inflammation and promotes recovery after ischemic injury. J Cereb Blood Flow Metab 29: 820-829, 2009.
-
(2009)
J Cereb Blood Flow Metab
, vol.29
, pp. 820-829
-
-
Kauppinen, T.M.1
Suh, S.W.2
Berman, A.E.3
Hamby, A.M.4
Swanson, R.A.5
-
11
-
-
22544487228
-
Early nuclear translocation of endonuclease G and subsequent DNA fragmentation after transient focal cerebral ischemia in mice
-
Lee BI, Lee DJ, Cho KJ, Kim GW. Early nuclear translocation of endonuclease G and subsequent DNA fragmentation after transient focal cerebral ischemia in mice. Neurosci Lett 386: 23-27, 2005.
-
(2005)
Neurosci Lett
, vol.386
, pp. 23-27
-
-
Lee, B.I.1
Lee, D.J.2
Cho, K.J.3
Kim, G.W.4
-
12
-
-
0035811496
-
Endonuclease G is an apoptotic DNase when released from mitochondria
-
Li LY, Luo X, Wang X. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 412: 95-99, 2001.
-
(2001)
Nature
, vol.412
, pp. 95-99
-
-
Li, L.Y.1
Luo, X.2
Wang, X.3
-
13
-
-
33751500940
-
Influence of duration of focal cerebral ischemia and neuronal nitric oxide synthase on translocation of apoptosis-inducing factor to the nucleus
-
Li X, Nemoto M, Xu Z, Yu SW, Shimoji M, Andrabi SA, Haince JF, Poirier GG, Dawson TM, Dawson VL, Koehler RC. Influence of duration of focal cerebral ischemia and neuronal nitric oxide synthase on translocation of apoptosis-inducing factor to the nucleus. Neuroscience 144: 56-65, 2007.
-
(2007)
Neuroscience
, vol.144
, pp. 56-65
-
-
Li, X.1
Nemoto, M.2
Xu, Z.3
Yu, S.W.4
Shimoji, M.5
Andrabi, S.A.6
Haince, J.F.7
Poirier, G.G.8
Dawson, T.M.9
Dawson, V.L.10
Koehler, R.C.11
-
14
-
-
0032507585
-
Differences in the cerebrovascular anatomy of C57Black/6 and SV129 mice
-
Maeda K, Hata R, Hossmann KA. Differences in the cerebrovascular anatomy of C57black/6 and SV129 mice. Neuroreport 9: 1317-1319, 1998. (Pubitemid 28264243)
-
(1998)
NeuroReport
, vol.9
, Issue.7
, pp. 1317-1319
-
-
Maeda, K.1
Hata, R.2
Hossmann, K.-A.3
-
15
-
-
17044430692
-
Ischemic nitric oxide and poly (ADP-ribose) polymerase-1 in cerebral ischemia: Male toxicity, female protection
-
McCullough LD, Zeng Z, Blizzard KK, Debchoudhury I, Hurn PD. Ischemic nitric oxide and poly (ADP-ribose) polymerase-1 in cerebral ischemia: male toxicity, female protection. J Cereb Blood Flow Metab 25: 502-512, 2005.
-
(2005)
J Cereb Blood Flow Metab
, vol.25
, pp. 502-512
-
-
McCullough, L.D.1
Zeng, Z.2
Blizzard, K.K.3
Debchoudhury, I.4
Hurn, P.D.5
-
16
-
-
13244267045
-
A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 (2-methyl-3,5,7,8-tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one): Pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats
-
Nakajima H, Kakui N, Ohkuma K, Ishikawa M, Hasegawa T. A newly synthesized poly(ADP-ribose) polymerase inhibitor, DR2313 (2-methyl-3,5,7,8- tetrahydrothiopyrano[4,3-d]-pyrimidine-4-one): pharmacological profiles, neuroprotective effects, and therapeutic time window in cerebral ischemia in rats. J Pharmacol Exp Ther 312: 472-481, 2005.
-
(2005)
J Pharmacol Exp Ther
, vol.312
, pp. 472-481
-
-
Nakajima, H.1
Kakui, N.2
Ohkuma, K.3
Ishikawa, M.4
Hasegawa, T.5
-
17
-
-
62149089916
-
Nuclear translocation of endonuclease G in degenerating neurons after permanent middle cerebral artery occlusion in mice
-
Nielsen M, Lambertsen KL, Clausen BH, Meldgaard M, Diemer NH, Zimmer J, Finsen B. Nuclear translocation of endonuclease G in degenerating neurons after permanent middle cerebral artery occlusion in mice. Exp Brain Res 194: 17-27, 2009.
-
(2009)
Exp Brain Res
, vol.194
, pp. 17-27
-
-
Nielsen, M.1
Lambertsen, K.L.2
Clausen, B.H.3
Meldgaard, M.4
Diemer, N.H.5
Zimmer, J.6
Finsen, B.7
-
18
-
-
49649123708
-
Endonuclease G expression in thalamic reticular nucleus after global cerebral ischemia
-
Nielsen M, Zimmer J, Diemer NH. Endonuclease G expression in thalamic reticular nucleus after global cerebral ischemia. Exp Brain Res 190: 81-89, 2008.
-
(2008)
Exp Brain Res
, vol.190
, pp. 81-89
-
-
Nielsen, M.1
Zimmer, J.2
Diemer, N.H.3
-
19
-
-
0035811511
-
Mitochondrial endonuclease G is important for apoptosis in C. elegans
-
Parrish J, Li L, Klotz K, Ledwich D, Wang X, Xue D. Mitochondrial endonuclease G is important for apoptosis in C. elegans. Nature 412: 90-94, 2001.
-
(2001)
Nature
, vol.412
, pp. 90-94
-
-
Parrish, J.1
Li, L.2
Klotz, K.3
Ledwich, D.4
Wang, X.5
Xue, D.6
-
20
-
-
70350493719
-
Critical role of poly(ADPribose) polymerase-1 in modulating the mode of cell death caused by continuous oxidative stress
-
Son YO, Kook SH, Jang YS, Shi X, Lee JC. Critical role of poly(ADPribose) polymerase-1 in modulating the mode of cell death caused by continuous oxidative stress. J Cell Biochem 108: 989-997, 2009.
-
(2009)
J Cell Biochem
, vol.108
, pp. 989-997
-
-
Son, Y.O.1
Kook, S.H.2
Jang, Y.S.3
Shi, X.4
Lee, J.C.5
-
21
-
-
0030862138
-
Neuroprotective effects of inhibiting poly(ADP-ribose) synthetase on focal cerebral ischemia in rats
-
Takahashi K, Greenberg JH, Jackson P, Maclin K, Zhang J. Neuroprotective effects of inhibiting poly(ADP-ribose) synthetase on focal cerebral ischemia in rats. J Cereb Blood Flow Metab 17: 1137-1142, 1997. (Pubitemid 27514737)
-
(1997)
Journal of Cerebral Blood Flow and Metabolism
, vol.17
, Issue.11
, pp. 1137-1142
-
-
Takahashi, K.1
Greenberg, J.H.2
Jackson, P.3
Maclin, K.4
Zhang, J.5
-
22
-
-
25644443963
-
Mitochondrial impairment induced by poly(ADPribose) polymerase-1 activation in cortical neurons after oxygen and glucose deprivation
-
Tanaka S, Takehashi M, Iida S, Kitajima T, Kamanaka Y, Stedeford T, Banasik M, Ueda K. Mitochondrial impairment induced by poly(ADPribose) polymerase-1 activation in cortical neurons after oxygen and glucose deprivation. J Neurochem 95: 179-190, 2005.
-
(2005)
J Neurochem
, vol.95
, pp. 179-190
-
-
Tanaka, S.1
Takehashi, M.2
Iida, S.3
Kitajima, T.4
Kamanaka, Y.5
Stedeford, T.6
Banasik, M.7
Ueda, K.8
-
23
-
-
0035674047
-
Endonuclease G: A mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation
-
van Loo G, Schotte P, van Gurp M, Demol H, Hoorelbeke B, Gevaert K, Rodriguez I, Ruiz-Carrillo A, Vandekerckhove J, Declercq W, Beyaert R, Vandenabeele P. Endonuclease G: a mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation. Cell Death Differ 8: 1136-1142, 2001.
-
(2001)
Cell Death Differ
, vol.8
, pp. 1136-1142
-
-
Van Loo, G.1
Schotte, P.2
Van Gurp, M.3
Demol, H.4
Hoorelbeke, B.5
Gevaert, K.6
Rodriguez, I.7
Ruiz-Carrillo, A.8
Vandekerckhove, J.9
Declercq, W.10
Beyaert, R.11
Vandenabeele, P.12
-
24
-
-
67749130818
-
Reactive oxygen species-induced cell death of rat primary astrocytes through mitochondria-mediated mechanism
-
Wang CC, Fang KM, Yang CS, Tzeng SF. Reactive oxygen species-induced cell death of rat primary astrocytes through mitochondria-mediated mechanism. J Cell Biochem 107: 933-943, 2009.
-
(2009)
J Cell Biochem
, vol.107
, pp. 933-943
-
-
Wang, C.C.1
Fang, K.M.2
Yang, C.S.3
Tzeng, S.F.4
-
25
-
-
0037159784
-
Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans
-
Wang X, Yang C, Chai J, Shi Y, Xue D. Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans. Science 298: 1587-1592, 2002.
-
(2002)
Science
, vol.298
, pp. 1587-1592
-
-
Wang, X.1
Yang, C.2
Chai, J.3
Shi, Y.4
Xue, D.5
-
26
-
-
33646578441
-
Overexpression of SOD1 in transgenic rats attenuates nuclear translocation of endonuclease G and apoptosis after spinal cord injury
-
Yu F, Sugawara T, Nishi T, Liu J, Chan PH. Overexpression of SOD1 in transgenic rats attenuates nuclear translocation of endonuclease G and apoptosis after spinal cord injury. J Neurotrauma 23: 595-603, 2006. (Pubitemid 43728049)
-
(2006)
Journal of Neurotrauma
, vol.23
, Issue.5
, pp. 595-603
-
-
Yu, F.1
Sugawara, T.2
Nishi, T.3
Liu, J.4
Chan, P.H.5
-
27
-
-
33845317242
-
Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death
-
Yu SW, Andrabi SA, Wang H, Kim NS, Poirier GG, Dawson TM, Dawson VL. Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death. Proc Natl Acad Sci U S A 103: 18314-18319, 2006.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 18314-18319
-
-
Yu, S.W.1
Andrabi, S.A.2
Wang, H.3
Kim, N.S.4
Poirier, G.G.5
Dawson, T.M.6
Dawson, V.L.7
-
28
-
-
0037067317
-
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
-
Yu SW, Wang H, Poitras MF, Coombs C, Bowers WJ, Federoff HJ, Poirier GG, Dawson TM, Dawson VL. Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science 297: 259-263, 2002.
-
(2002)
Science
, vol.297
, pp. 259-263
-
-
Yu, S.W.1
Wang, H.2
Poitras, M.F.3
Coombs, C.4
Bowers, W.J.5
Federoff, H.J.6
Poirier, G.G.7
Dawson, T.M.8
Dawson, V.L.9
-
29
-
-
64249104435
-
Sex differences in the response to activation of the poly (ADP-ribose) polymerase pathway after experimental stroke
-
Yuan M, Siegel C, Zeng Z, Li J, Liu F, McCullough LD. Sex differences in the response to activation of the poly (ADP-ribose) polymerase pathway after experimental stroke. Exp Neurol 217: 210-218, 2009.
-
(2009)
Exp Neurol
, vol.217
, pp. 210-218
-
-
Yuan, M.1
Siegel, C.2
Zeng, Z.3
Li, J.4
Liu, F.5
McCullough, L.D.6
-
30
-
-
9144244327
-
Endonuclease G is required for early embryogenesis and normal apoptosis in mice
-
Zhang J, Dong M, Li L, Fan Y, Pathre P, Dong J, Lou D, Wells JM, Olivares-Villagomez D, van Kaer L, Wang X, Xu M. Endonuclease G is required for early embryogenesis and normal apoptosis in mice. Proc Natl Acad Sci U S A 100: 15782-15787, 2003.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 15782-15787
-
-
Zhang, J.1
Dong, M.2
Li, L.3
Fan, Y.4
Pathre, P.5
Dong, J.6
Lou, D.7
Wells, J.M.8
Olivares-Villagomez, D.9
Van Kaer, L.10
Wang, X.11
Xu, M.12
-
31
-
-
0032514713
-
Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45
-
DOI 10.1073/pnas.95.21.12480
-
Zhang J, Liu X, Scherer DC, van Kaer L, Wang X, Xu M. Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45. Proc Natl Acad Sci U S A 95: 12480-12485, 1998. (Pubitemid 28483790)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.21
, pp. 12480-12485
-
-
Zhang, J.1
Liu, X.2
Scherer, D.C.3
Van Kaer, L.4
Wang, X.5
Xu, M.6
-
32
-
-
41249098470
-
Delayed tolerance with repetitive transient focal ischemic preconditioning in the mouse
-
Zhang J, Yang ZJ, Klaus JA, Koehler RC, Huang J. Delayed tolerance with repetitive transient focal ischemic preconditioning in the mouse. Stroke 39: 967-974, 2008.
-
(2008)
Stroke
, vol.39
, pp. 967-974
-
-
Zhang, J.1
Yang, Z.J.2
Klaus, J.A.3
Koehler, R.C.4
Huang, J.5
-
33
-
-
34247572412
-
BNIP3 upregulation and EndoG translocation in delayed neuronal death in stroke and in hypoxia
-
Zhang Z, Yang X, Zhang S, Ma X, Kong J. BNIP3 upregulation and EndoG translocation in delayed neuronal death in stroke and in hypoxia. Stroke 38: 1606-1613, 2007.
-
(2007)
Stroke
, vol.38
, pp. 1606-1613
-
-
Zhang, Z.1
Yang, X.2
Zhang, S.3
Ma, X.4
Kong, J.5
-
34
-
-
70349777973
-
Mitochondrial BNIP3 upregulation precedes endonuclease G translocation in hippocampal neuronal death following oxygen-glucose deprivation
-
Zhao ST, Chen M, Li SJ, Zhang MH, Li BX, Das M, Bean JC, Kong JM, Zhu XH, Gao TM. Mitochondrial BNIP3 upregulation precedes endonuclease G translocation in hippocampal neuronal death following oxygen-glucose deprivation. BMC Neurosci 10: 113, 2009.
-
(2009)
BMC Neurosci
, vol.10
, pp. 113
-
-
Zhao, S.T.1
Chen, M.2
Li, S.J.3
Zhang, M.H.4
Li, B.X.5
Das, M.6
Bean, J.C.7
Kong, J.M.8
Zhu, X.H.9
Gao, T.M.10
-
35
-
-
33645100937
-
Different apoptotic mechanisms are activated in male and female brains after neonatal hypoxia-ischaemia
-
Zhu C, Xu F, Wang X, Shibata M, Uchiyama Y, Blomgren K, Hagberg H. Different apoptotic mechanisms are activated in male and female brains after neonatal hypoxia-ischaemia. J Neurochem 96: 1016-1027, 2006.
-
(2006)
J Neurochem
, vol.96
, pp. 1016-1027
-
-
Zhu, C.1
Xu, F.2
Wang, X.3
Shibata, M.4
Uchiyama, Y.5
Blomgren, K.6
Hagberg, H.7
|