-
1
-
-
0027818316
-
Etiology of nasopharyngeal carcinoma: A review
-
Hildesheim A, Levine PH. Etiology of nasopharyngeal carcinoma: a review. Epidemiol Rev 1993;15:466-485.
-
(1993)
Epidemiol Rev
, vol.15
, pp. 466-485
-
-
Hildesheim, A.1
Levine, P.H.2
-
2
-
-
33846705453
-
Nasopharyngeal carcinoma: Molecular biomarker discovery and progress
-
Cho WC. Nasopharyngeal carcinoma: molecular biomarker discovery and progress. Mol Cancer 2007;6:1-9.
-
(2007)
Mol Cancer
, vol.6
, pp. 1-9
-
-
Cho, W.C.1
-
3
-
-
33745810224
-
Construction of evolutionary tree models for nasopharyngeal carcinoma using comparative genomic hybridization data
-
Wu LS-H. Construction of evolutionary tree models for nasopharyngeal carcinoma using comparative genomic hybridization data. Cancer Genet Cytogenet 2006;168:105-108.
-
(2006)
Cancer Genet Cytogenet
, vol.168
, pp. 105-108
-
-
Wu, L.S.-H.1
-
4
-
-
0032532485
-
Mapping of the human PAWR (par-4) gene to chromosome 12q21
-
DOI 10.1006/geno.1998.5494
-
Johnstone RW, Tommerup N, Hansen C, Vissing H, Shi Y. Mapping of the human PAWR (par-4) gene to chromosome 12q21. Genomics 1998;53:241-243. (Pubitemid 28496616)
-
(1998)
Genomics
, vol.53
, Issue.2
, pp. 241-243
-
-
Johnstone, R.W.1
Tommerup, N.2
Hansen, C.3
Vissing, H.4
Shi, Y.5
-
5
-
-
0028015669
-
Commonality of the gene programs induced by effectors of apoptosis in androgen-dependent and -independent prostate cells
-
Sells SF, Wood DP Jr, Joshi-Barve SS, et al. Commonality of the gene programs induced by effectors of apoptosis in androgen-dependent and -independent prostate cells. Cell Growth Differ 1994;5:457-466.
-
(1994)
Cell Growth Differ
, vol.5
, pp. 457-466
-
-
Sells, S.F.1
Wood Jr., D.P.2
Joshi-Barve, S.S.3
-
7
-
-
25844454851
-
Binding and phosphorylation of par-4 by Akt is essential for cancer cell survival
-
Goswami A, Burikhanov R, de Thonel A, et al. Binding and phosphorylation of par-4 by Akt is essential for cancer cell survival. Mol Cell 2005;20:33-44.
-
(2005)
Mol Cell
, vol.20
, pp. 33-44
-
-
Goswami, A.1
Burikhanov, R.2
De Thonel, A.3
-
8
-
-
0030572696
-
The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C
-
Diaz-Meco MT, Municio MM, Frutos S, et al. The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C. Cell 1996;86:777-786.
-
(1996)
Cell
, vol.86
, pp. 777-786
-
-
Diaz-Meco, M.T.1
Municio, M.M.2
Frutos, S.3
-
9
-
-
10544225383
-
A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1
-
Johnstone RW, See RH, Sells SF, et al. A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1. Mol Cell Biol 1996;16:6945-6956.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6945-6956
-
-
Johnstone, R.W.1
See, R.H.2
Sells, S.F.3
-
10
-
-
0035477544
-
Par-4 drives trafficking and activation of Fas and FasL to induce prostate cancer cell apoptosis and tumor regression
-
Chakraborty M, Qiu SG, Vasudevan KM, Rangnekar VM. Par-4 drives trafficking and activation of Fas and FasL to induce prostate cancer cell apoptosis and tumor regression. Cancer Res 2001;61:7255-7263. (Pubitemid 32946523)
-
(2001)
Cancer Research
, vol.61
, Issue.19
, pp. 7255-7263
-
-
Chakraborty, M.1
Qiu, S.G.2
Vasudevan, K.M.3
Rangnekar, V.M.4
-
11
-
-
33644858149
-
Par-4: A common facilitator/enhancer of extrinsic and intrinsic pathways of apoptosis
-
Mundle SD. Par-4: a common facilitator/enhancer of extrinsic and intrinsic pathways of apoptosis. Leuk Res 2006;30:515-517.
-
(2006)
Leuk Res
, vol.30
, pp. 515-517
-
-
Mundle, S.D.1
-
12
-
-
20744447485
-
Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells
-
Pruitt K, Ülkü AS, Frantz K, et al. Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells. J Biol Chem 2005;280:23363-23370.
-
(2005)
J Biol Chem
, vol.280
, pp. 23363-23370
-
-
Pruitt, K.1
Ülkü, A.S.2
Frantz, K.3
-
13
-
-
0033604464
-
Negative regulation of Par-4 by oncogenic Ras is essential for cellular transformation
-
Qiu SG, Krishnan S, el-Guendy N, Rangnekar VM. Negative regulation of Par-4 by oncogenic Ras is essential for cellular transformation. Oncogene 1999;18:7115-7123.
-
(1999)
Oncogene
, vol.18
, pp. 7115-7123
-
-
Qiu, S.G.1
Krishnan, S.2
El-Guendy, N.3
Rangnekar, V.M.4
-
14
-
-
0033570123
-
Oncogenic Ras sensitizes cells to apoptosis by Par-4
-
Nalca A, Qiu SG, el-Guendy N, Krishnan S, Rangnekar VM. Oncogenic Ras sensitizes cells to apoptosis by Par-4. J Biol Chem 1999;274:29976-29983.
-
(1999)
J Biol Chem
, vol.274
, pp. 29976-29983
-
-
Nalca, A.1
Qiu, S.G.2
El-Guendy, N.3
Krishnan, S.4
Rangnekar, V.M.5
-
15
-
-
0033570912
-
The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression
-
Barradas M, Monjas A, Diaz-Meco MT, Serrano M, Moscat J. The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression. EMBO J 1999;18:6362-6369.
-
(1999)
EMBO J
, vol.18
, pp. 6362-6369
-
-
Barradas, M.1
Monjas, A.2
Diaz-Meco, M.T.3
Serrano, M.4
Moscat, J.5
-
16
-
-
22144496103
-
Tumor-suppression activity of the proapoptotic regulator Par4
-
Garcia-Cao I, Duran A, Collado M, et al. Tumor-suppression activity of the proapoptotic regulator Par4. EMBO Rep 2005;6:577-583.
-
(2005)
EMBO Rep
, vol.6
, pp. 577-583
-
-
Garcia-Cao, I.1
Duran, A.2
Collado, M.3
-
17
-
-
0037381871
-
Par-4 for molecular therapy of prostate cancer
-
Butler J, Rangnekar VM. Par-4 for molecular therapy of prostate cancer. Curr Drug Targets 2003;4:223-230.
-
(2003)
Curr Drug Targets
, vol.4
, pp. 223-230
-
-
Butler, J.1
Rangnekar, V.M.2
-
18
-
-
35148887346
-
Protein expression and intracellular localization of prostate apoptosis response-4 (Par-4) are associated with apoptosis induction in nasopharyngeal carcinoma cell lines
-
Lee JW, Lee KF, Hsu HY, et al. Protein expression and intracellular localization of prostate apoptosis response-4 (Par-4) are associated with apoptosis induction in nasopharyngeal carcinoma cell lines. Cancer Lett 2007;257:252-262.
-
(2007)
Cancer Lett
, vol.257
, pp. 252-262
-
-
Lee, J.W.1
Lee, K.F.2
Hsu, H.Y.3
-
19
-
-
0038504065
-
Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter
-
Cheema SK, Mishra SK, Rangnekar VM, Tari AM, Kumar R, Lopez-Berestein G. Par-4 transcriptionally regulates Bcl-2 through a WT1-binding site on the bcl-2 promoter. J Biol Chem 2003;278:19995-20005.
-
(2003)
J Biol Chem
, vol.278
, pp. 19995-20005
-
-
Cheema, S.K.1
Mishra, S.K.2
Rangnekar, V.M.3
Tari, A.M.4
Kumar, R.5
Lopez-Berestein, G.6
-
20
-
-
0008881181
-
Mutually exclusive expression patterns of Bcl-2 and Par-4 in human prostate tumors consistent with down-regulation of Bcl-2 by Par-4
-
Qiu G, Ahmed M, Sells SF, Mohiuddin M, Weinstein MH, Rangnekar VM. Mutually exclusive expression patterns of Bcl-2 and Par-4 in human prostate tumors consistent with down-regulation of Bcl-2 by Par-4. Oncogene 1999;18:623-631.
-
(1999)
Oncogene
, vol.18
, pp. 623-631
-
-
Qiu, G.1
Ahmed, M.2
Sells, S.F.3
Mohiuddin, M.4
Weinstein, M.H.5
Rangnekar, V.M.6
-
21
-
-
0036433743
-
Genetic and epigenetic changes in nasopharyngeal carcinoma
-
Lo KW, Huang DP. Genetic and epigenetic changes in nasopharyngeal carcinoma. Semin Cancer Biol 2002;12:451-462.
-
(2002)
Semin Cancer Biol
, vol.12
, pp. 451-462
-
-
Lo, K.W.1
Huang, D.P.2
-
22
-
-
0037086078
-
In lymphatic cells par-4 sensitizes to apoptosis by down-regulating bcl-2 and promoting disruption of mitochondrial membrane potential and caspase activation
-
Boehrer S, Chow KU, Beske F, et al. In lymphatic cells par-4 sensitizes to apoptosis by down-regulating bcl-2 and promoting disruption of mitochondrial membrane potential and caspase activation. Cancer Res 2002;62:1768-1775.
-
(2002)
Cancer Res
, vol.62
, pp. 1768-1775
-
-
Boehrer, S.1
Chow, K.U.2
Beske, F.3
-
23
-
-
33646395652
-
Cell death regulation by B-cell lymphoma protein
-
Verma YK, Gangenahalli GU, Singh VK, et al. Cell death regulation by B-cell lymphoma protein. Apoptosis 2006;11:459-471.
-
(2006)
Apoptosis
, vol.11
, pp. 459-471
-
-
Verma, Y.K.1
Gangenahalli, G.U.2
Singh, V.K.3
-
24
-
-
0043133881
-
Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells
-
El-Guendy N, Zhao Y, Gurumurthy S, Burikhanov R, Rangnekar VM. Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells. Mol Cell Biol 2003;23:5516-5525.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5516-5525
-
-
El-Guendy, N.1
Zhao, Y.2
Gurumurthy, S.3
Burikhanov, R.4
Rangnekar, V.M.5
-
25
-
-
33645733587
-
Targeted ablation of Par-4 reveals a cell type-specific susceptibility to apoptosis-inducing agents
-
Affar El B, Luke MP, Gay F, et al. Targeted ablation of Par-4 reveals a cell type-specific susceptibility to apoptosis-inducing agents. Cancer Res 2006;66:3456-3462.
-
(2006)
Cancer Res
, vol.66
, pp. 3456-3462
-
-
Affar El, B.1
Luke, M.P.2
Gay, F.3
-
26
-
-
67349178306
-
EBV LMP-1 negatively regulates expression and proapoptotic activity of Par-4 in nasopharyngeal carcinoma cells
-
Lee JW, Liu PF, Hsu LP, Chen PR, Chang CH, Shih WL. EBV LMP-1 negatively regulates expression and proapoptotic activity of Par-4 in nasopharyngeal carcinoma cells. Cancer Lett 2009;279:193-201.
-
(2009)
Cancer Lett
, vol.279
, pp. 193-201
-
-
Lee, J.W.1
Liu, P.F.2
Hsu, L.P.3
Chen, P.R.4
Chang, C.H.5
Shih, W.L.6
-
27
-
-
33645524134
-
The phosphinositide 3-kinase/Akt1/Par-4 axis: A cancer-selective therapeutic target
-
Goswami A, Ranganathan P, Rangnekar VM. The phosphinositide 3-kinase/Akt1/Par-4 axis: a cancer-selective therapeutic target. Cancer Res 2006;66:2889-2892.
-
(2006)
Cancer Res
, vol.66
, pp. 2889-2892
-
-
Goswami, A.1
Ranganathan, P.2
Rangnekar, V.M.3
-
28
-
-
33947196921
-
Inactivation of the candidate tumor suppressor Par-4 in endometrial cancer
-
DOI 10.1158/0008-5472.CAN-06-2687
-
Moreno-Bueno G, Fernandez-Marcos PJ, Collado M, et al. Inactivation of the candidate tumor suppressor par-4 in endometrial cancer. Cancer Res 2007;67:1927-1934. (Pubitemid 46424208)
-
(2007)
Cancer Research
, vol.67
, Issue.5
, pp. 1927-1934
-
-
Moreno-Bueno, G.1
Fernandez-Marcos, P.J.2
Collado, M.3
Tendero, M.J.4
Rodriguez-Pinilla, S.M.5
Garcia-Cao, I.6
Hardisson, D.7
Diaz-Meco, M.T.8
Moscat, J.9
Serrano, M.10
Palacios, J.11
-
29
-
-
0033521923
-
Decreased expression of the pro-apoptotic protein Par-4 in renal cell carcinoma
-
Cook J, Krishnan S, Ananth S, et al. Decreased expression of the pro-apoptotic protein Par-4 in renal cell carcinoma. Oncogene 1999;18:1205-1208.
-
(1999)
Oncogene
, vol.18
, pp. 1205-1208
-
-
Cook, J.1
Krishnan, S.2
Ananth, S.3
-
30
-
-
0035022291
-
Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia
-
Boehrer S, Chow KU, Puccetti E, et al. Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia. Hematol J 2001;2:103-107.
-
(2001)
Hematol J
, vol.2
, pp. 103-107
-
-
Boehrer, S.1
Chow, K.U.2
Puccetti, E.3
-
31
-
-
17244367849
-
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
-
DOI 10.1038/nature03482
-
Bartkova J, Hořejší Z, Koed K, et al. DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature 2005;434:864-870. (Pubitemid 40558993)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 864-870
-
-
Bartkova, J.1
Horejsi, Z.2
Koed, K.3
Kramer, A.4
Tort, F.5
Zleger, K.6
Guldberg, P.7
Sehested, M.8
Nesland, J.M.9
Lukas, C.10
Orntoft, T.11
Lukas, J.12
Bartek, J.13
-
32
-
-
17244366865
-
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
-
DOI 10.1038/nature03485
-
Gorgoulis VG, Vassiliou LV, Karakaidos P, et al. Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature 2005;434:907-913. (Pubitemid 40559004)
-
(2005)
Nature
, vol.434
, Issue.7035
, pp. 907-913
-
-
Gorgoulis, V.G.1
Vassiliou, L.-V.F.2
Karakaidos, P.3
Zacharatos, P.4
Kotsinas, A.5
Liloglou, T.6
Venere, M.7
Ditullio Jr., R.A.8
Kastrinakis, N.G.9
Levy, B.10
Kletsas, D.11
Yoneta, A.12
Herlyn, M.13
Kittas, C.14
Halazonetis, T.D.15
-
33
-
-
0036513029
-
Oncogenic resistance to growth-limiting conditions
-
Blagosklonny MV. Oncogenic resistance to growth-limiting conditions. Nat Rev Cancer 2002;2:221-225.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 221-225
-
-
Blagosklonny, M.V.1
-
34
-
-
9244224723
-
Intrinsic tumor suppression
-
Lowe SW, Cepero E, Evan G. Intrinsic tumor suppression. Nature 2004;432:307-315.
-
(2004)
Nature
, vol.432
, pp. 307-315
-
-
Lowe, S.W.1
Cepero, E.2
Evan, G.3
-
35
-
-
33745932649
-
Molecular mediators of cell death in multistep carcinogenesis: A path to targeted therapy
-
Spurgers KB, Chari NS, Bohnenstiehl NL, McDonnell TJ. Molecular mediators of cell death in multistep carcinogenesis: a path to targeted therapy. Cell Death Differ 2006;13:1360-1370.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1360-1370
-
-
Spurgers, K.B.1
Chari, N.S.2
Bohnenstiehl, N.L.3
McDonnell, T.J.4
|