Design, synthesis, and urease inhibition studies of some 1,3,4-oxadiazoles and 1,2,4-triazoles derived from mandelic acid

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 25, Issue 4, 2010, Pages 572-576

  Akhtar, Tashfeen ^a   Hameed, Shahid ^a   Khan, Khalid M ^b   Khan, Ajmal ^b   Choudhary, Muhammad Iqbal ^b  

^a QUAID I AZAM UNIVERSITY   (Pakistan)

^b UNIVERSITY OF KARACHI   (Pakistan)

Author keywords

Mandelic acid; Oxadiazoles; Thiosemicarbazides; Triazoles; Urease inhibition

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; 1,3,4 OXADIAZOLE DERIVATIVE; 5 (HYDROXYBENZYL) 2 (4 BROMOPHENYL)AMINO 1,3,4 OXADIAZOLE; 5 (HYDROXYBENZYL) 2 (4 CHLOROPHENYL)AMINO 1,3,4 OXADIAZOLE; 5 (HYDROXYBENZYL) 2 (4 FLUOROPHENYL)AMINO 1,3,4 OXADIAZOLE; 5 (HYDROXYBENZYL) 2 (4 METHYLPHENYL)AMINO 1,3,4 OXADIAZOLE; 5 (HYDROXYBENZYL) 2 (4 NITROPHENYL)AMINO 1,3,4 OXADIAZOLE; 5 (HYDROXYBENZYL) 4 (4 BROMOPHENYL) 2H 1,2,4 TRIAZOLE 3 THIONE; 5 (HYDROXYBENZYL) 4 (4 CHLOROPHENYL) 2H 1,2,4 TRIAZOLE 3 THIONE; 5 (HYDROXYBENZYL) 4 (4 FLUOROPHENYL) 2H 1,2,4 TRIAZOLE 3 THIONE; 5 (HYDROXYBENZYL) 4 (4 METHYLPHENYL) 2H 1,2,4 TRIAZOLE 3 THIONE; 5 (HYDROXYBENZYL) 4 (4 NITROPHENYL) 2H 1,2,4 TRIAZOLE 3 THIONE; HYDRAZIDE DERIVATIVE; ISOTHIOCYANIC ACID DERIVATIVE; MANDELIC ACID; THIOUREA; UNCLASSIFIED DRUG; UREASE; 1,2,4-TRIAZOLE; ANTIULCER AGENT; ENZYME INHIBITOR; MANDELIC ACID DERIVATIVE; OXADIAZOLE DERIVATIVE; TRIAZOLE DERIVATIVE;

ARTICLE; CONTROLLED STUDY; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; ESTERIFICATION; IC 50; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; ANTAGONISTS AND INHIBITORS; CHEMISTRY; HUMAN; IC50; SYNTHESIS;

CANAVALIA ENSIFORMIS;

ANTI-ULCER AGENTS; DRUG DESIGN; ENZYME INHIBITORS; HUMANS; INHIBITORY CONCENTRATION 50; MANDELIC ACIDS; OXADIAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES; UREASE;

EID: 77954411500     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756360903389864     Document Type: Article

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