Noninvasive visualization of in vivo release and intratumoral distribution of surrogate MR contrast agent using the dual MR contrast technique

Biomaterials

Volumn 31, Issue 27, 2010, Pages 7132-7138

  Onuki, Yoshinori ^a,c   Jacobs, Igor ^b   Artemov, Dmitri ^a   Kato, Yoshinori ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EINDHOVEN UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c HOSHI UNIVERSITY   (Japan)

Author keywords

Drug release; In vivo test; Molecular imaging; MRI (magnetic resonance imaging); Nanoparticle

Indexed keywords

5-FLUOROURACIL; CONTRAST AGENT; DISTRIBUTION PROFILES; DRUG CARRIER; DRUG DELIVERY SYSTEM; DRUG RELEASE; GD-DTPA; HUMAN BREAST CANCER; IN-VITRO; IN-VIVO; IN-VIVO TESTS; MOLECULAR IMAGING; MR CONTRAST AGENTS; MRI (MAGNETIC RESONANCE IMAGING); NON-INVASIVE MONITORING; NONINVASIVE VISUALIZATION; ORTHOTOPIC; POLY(D ,L-LACTIDE-CO- GLYCOLIDE); PROOF OF PRINCIPLES; RELEASE PROFILES; SINGLE CARRIER; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES;

CONTROLLED DRUG DELIVERY; IRON OXIDES; MAGNETIC RESONANCE; NANOMAGNETICS; NANOPARTICLES; ORGANIC POLYMERS; SUPERPARAMAGNETISM; VISUALIZATION;

MAGNETIC RESONANCE IMAGING;

DRUG CARRIER; FLUOROURACIL; GADODIAMIDE; MICROSPHERE; NANOSPHERE; POLYGLACTIN; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; CONTRAST MEDIUM; FERRIC ION; FERRIC OXIDE; LACTIC ACID; NANOPARTICLE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CONTROLLED STUDY; DRUG RELEASE; FEMALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; TUMOR XENOGRAFT; ANIMAL; CHEMISTRY; HUMAN; PROCEDURES; SCID MOUSE; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CONTRAST MEDIA; FERRIC COMPOUNDS; FLUOROURACIL; HUMANS; LACTIC ACID; MAGNETIC RESONANCE IMAGING; MICE; MICE, SCID; MICROSPHERES; NANOPARTICLES; NANOSPHERES; POLYGLYCOLIC ACID;

EID: 77954383140     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.06.008     Document Type: Article

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