메뉴 건너뛰기




Volumn 70, Issue 13, 2010, Pages 5549-5557

A mouse model of melanoma driven by oncogenic KRAS

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; K RAS PROTEIN;

EID: 77954358935     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-09-4254     Document Type: Article
Times cited : (65)

References (26)
  • 1
    • 0037264633 scopus 로고    scopus 로고
    • Targeting RAS signalling pathways in cancer therapy
    • DOI 10.1038/nrc969
    • Downward J. Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 2003;3:11-22. (Pubitemid 37328883)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.1 , pp. 11-22
    • Downward, J.1
  • 5
    • 0024376173 scopus 로고
    • Ras oncogenes in human cancer: A review
    • Bos JL. ras oncogenes in human cancer: a review. Cancer Res 1989; 49:4682-9.
    • (1989) Cancer Res , vol.49 , pp. 4682-4689
    • Bos, J.L.1
  • 6
    • 70449334132 scopus 로고    scopus 로고
    • Epidemiology, staging (new system), and prognosis of cutaneous melanoma
    • Cho YR, Chiang MP. Epidemiology, staging (new system), and prognosis of cutaneous melanoma. Clin Plast Surg 37:47-53.
    • Clin Plast Surg , vol.37 , pp. 47-53
    • Cho, Y.R.1    Chiang, M.P.2
  • 10
    • 0033614962 scopus 로고    scopus 로고
    • Essential role for oncogenic Ras in tumour maintenance
    • Chin L, Tam A, Pomerantz J, et al. Essential role for oncogenic Ras in tumour maintenance. Nature 1999;400:468-72.
    • (1999) Nature , vol.400 , pp. 468-472
    • Chin, L.1    Tam, A.2    Pomerantz, J.3
  • 11
    • 33644797263 scopus 로고    scopus 로고
    • Neonatal ultraviolet radiation exposure is critical for malignant melanoma induction in pigmented Tpras transgenic mice
    • Hacker E, Irwin N, Muller HK, et al. Neonatal ultraviolet radiation exposure is critical for malignant melanoma induction in pigmented Tpras transgenic mice. J Invest Dermatol 2005;125: 1074-7.
    • (2005) J Invest Dermatol , vol.125 , pp. 1074-1077
    • Hacker, E.1    Irwin, N.2    Muller, H.K.3
  • 12
    • 33645518844 scopus 로고    scopus 로고
    • An inducible mouse model of melanoma expressing a defined tumor antigen
    • Huijbers IJ, Krimpenfort P, Chomez P, et al. An inducible mouse model of melanoma expressing a defined tumor antigen. Cancer Res 2006;66:3278-86.
    • (2006) Cancer Res , vol.66 , pp. 3278-3286
    • Huijbers, I.J.1    Krimpenfort, P.2    Chomez, P.3
  • 13
    • 20144375230 scopus 로고    scopus 로고
    • Metastasizing melanoma formation caused by expression of activated N-RasQ61K on an INK4a-deficient background
    • Ackermann J, Frutschi M, Kaloulis K, McKee T, Trumpp A, Beermann F. Metastasizing melanoma formation caused by expression of activated N-RasQ61K on an INK4a-deficient background. Cancer Res 2005;65:4005-11.
    • (2005) Cancer Res , vol.65 , pp. 4005-4011
    • Ackermann, J.1    Frutschi, M.2    Kaloulis, K.3    McKee, T.4    Trumpp, A.5    Beermann, F.6
  • 14
    • 0035807255 scopus 로고    scopus 로고
    • Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene
    • Meuwissen R, Linn SC, van der Valk M, Mooi WJ, Berns A. Mouse model for lung tumorigenesis through Cre/lox controlled sporadic activation of the K-Ras oncogene. Oncogene 2001;20:6551-8.
    • (2001) Oncogene , vol.20 , pp. 6551-6558
    • Meuwissen, R.1    Linn, S.C.2    Van Der Valk, M.3    Mooi, W.J.4    Berns, A.5
  • 16
    • 63249105225 scopus 로고    scopus 로고
    • Oncogenic Braf induces melanocyte senescence and melanoma in mice
    • Dhomen N, Reis-Filho JS, da Rocha Dias S, et al. Oncogenic Braf induces melanocyte senescence and melanoma in mice. Cancer Cell 2009;15:294-303.
    • (2009) Cancer Cell , vol.15 , pp. 294-303
    • Dhomen, N.1    Reis-Filho, J.S.2    Da Rocha Dias, S.3
  • 17
    • 12144289677 scopus 로고    scopus 로고
    • Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
    • Wan PT, Garnett MJ, Roe SM, et al. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell 2004;116:855-67.
    • (2004) Cell , vol.116 , pp. 855-867
    • Wan, P.T.1    Garnett, M.J.2    Roe, S.M.3
  • 18
    • 77953123909 scopus 로고    scopus 로고
    • An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers
    • Natrajan R, Weigelt B, Mackay A, et al. An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers. Breast Cancer Res Treat 2009;121:575-89.
    • (2009) Breast Cancer Res Treat , vol.121 , pp. 575-589
    • Natrajan, R.1    Weigelt, B.2    Mackay, A.3
  • 19
    • 65249138229 scopus 로고    scopus 로고
    • Tiling path genomic profiling of grade 3 invasive ductal breast cancers
    • Natrajan R, Lambros MB, Rodriguez-Pinilla SM, et al. Tiling path genomic profiling of grade 3 invasive ductal breast cancers. Clin Cancer Res 2009;15:2711-22.
    • (2009) Clin Cancer Res , vol.15 , pp. 2711-2722
    • Natrajan, R.1    Lambros, M.B.2    Rodriguez-Pinilla, S.M.3
  • 20
    • 33746911642 scopus 로고    scopus 로고
    • EGFR amplification and lack of activating mutations in metaplastic breast carcinomas
    • Reis-Filho JS, Pinheiro C, Lambros MB, et al. EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. J Pathol 2006;209:445-53.
    • (2006) J Pathol , vol.209 , pp. 445-453
    • Reis-Filho, J.S.1    Pinheiro, C.2    Lambros, M.B.3
  • 21
    • 0347419011 scopus 로고    scopus 로고
    • Pigmented epithelioid melanocytoma: A low-grade melanocytic tumor with metastatic potential indistinguishable from animal-type melanoma and epithelioid blue nevus
    • Zembowicz A, Carney JA, Mihm MC. Pigmented epithelioid melanocytoma: a low-grade melanocytic tumor with metastatic potential indistinguishable from animal-type melanoma and epithelioid blue nevus. Am J Surg Pathol 2004;28:31-40.
    • (2004) Am J Surg Pathol , vol.28 , pp. 31-40
    • Zembowicz, A.1    Carney, J.A.2    Mihm, M.C.3
  • 23
    • 0032540355 scopus 로고    scopus 로고
    • Inhibition of the mitogen-activated protein kinase pathway triggers B16 melanoma cell differentiation
    • Englaro W, Bertolotto C, Buscà R, et al. Inhibition of the mitogen-activated protein kinase pathway triggers B16 melanoma cell differentiation. J Biol Chem 1998;273:9966-70.
    • (1998) J Biol Chem , vol.273 , pp. 9966-9970
    • Englaro, W.1    Bertolotto, C.2    Buscà, R.3
  • 24
    • 0028951685 scopus 로고
    • Hyperpigmentation and melanocytic hyperplasia in transgenic mice expressing the human T24 Ha-ras gene regulated by a mouse tyrosinase promoter
    • Powell MB, Hyman P, Bell OD, et al. Hyperpigmentation and melanocytic hyperplasia in transgenic mice expressing the human T24 Ha-ras gene regulated by a mouse tyrosinase promoter. Mol Carcinog 1995;12:82-90.
    • (1995) Mol Carcinog , vol.12 , pp. 82-90
    • Powell, M.B.1    Hyman, P.2    Bell, O.D.3
  • 25
    • 74849109743 scopus 로고    scopus 로고
    • Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF
    • Heidorn SJ, Milagre C, Whittaker S, et al. Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF. Cell 2010;140:209-21.
    • (2010) Cell , vol.140 , pp. 209-221
    • Heidorn, S.J.1    Milagre, C.2    Whittaker, S.3
  • 26
    • 0034998678 scopus 로고    scopus 로고
    • Compartmentalization of Ras proteins
    • Prior IA, Hancock JF. Compartmentalization of Ras proteins. J Cell Sci 2001;114:1603-8.
    • (2001) J Cell Sci , vol.114 , pp. 1603-1608
    • Prior, I.A.1    Hancock, J.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.