Amygdala volume correlates positively with fearfulness in normal healthy girls

Social Cognitive and Affective Neuroscience

Volumn 5, Issue 4, 2010, Pages 424-431

  van der Plas, Ellen A A ^a   Boes, Aaron D ^a   Wemmie, John A ^a   Tranel, Daniel ^a   Nopoulos, Peg ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Amygdala volume; Endophenotype; Fearfulness; Sex differences

Indexed keywords

ADOLESCENT; AMYGDALOID NUCLEUS; ARTICLE; CHILD; FEAR; FEMALE; HISTOLOGY; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; ORGAN SIZE; PHYSIOLOGY; PSYCHOLOGIC TEST; PSYCHOLOGICAL ASPECT; SEXUAL DEVELOPMENT;

ADOLESCENT; AMYGDALA; CHILD; FEAR; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; ORGAN SIZE; PSYCHOLOGICAL TESTS; SEX CHARACTERISTICS;

EID: 77954350327     PISSN: 17495016     EISSN: 17495024     Source Type: Journal    
DOI: 10.1093/scan/nsq009     Document Type: Article

References (60)

1. Achenbach, T.M., Edelbrock, C. (1983). Manual for the Child Behavior Checklist and Revised Child Behavior Profile. Burlington, VT: University of Vermont.
2. Adolphs, R., Tranel, D., Damasio, A.R. (1998). The human amygdala in social judgment. Nature, 393(6684), 470-4.
3. Adolphs, R., Tranel, D., Damasio, H., Damasio, A.R. (1995). Fear and the human amygdala. Journal of Neuroscience, 15(9), 5879-91.
4. Beardslee, W.R. (1993). The impact of parental affective disorder on depression in offspring: A longitudinal follow-up in a nonreferred sample. Journal of the American Academy of Child Adolescent Psychiatry, 32(4), 723.
5. Beardslee, W.R. (1998). Children of affectively ill parents: A review of the past 10 years. Journal of the American Academy of Child Adolescent Psychiatry, 37(11), 1134.
6. Bechara, A., Tranel, D., Damasio, H., Adolphs, R., Rockland, C., Damasio, A.R. (1995). Double dissociation of conditioning and declarative knowledge relative to the amygdala and hippocampus in humans. Science, 269(5227), 1115-8.
7. Boes, A.D. (2008). Neuroanatomical Correlates of Externalizing Behavior. Unpublished Doctor Dissertation, University of Iowa, 2008.
8. Bradley, M.M., Codispoti, M., Sabatinelli, D., Lang, P.J. (2001). Emotion and motivation II: sex differences in picture processing. Emotion, 1(3), 300.
9. Breton, J.J., Bergeron, L., Valla, J.P., Lepine, S., Houde, L., Gaudet, N. (1995). Do children aged 9 through 11 years understand the disc version-2.25 questions. Journal of the American Academy of Child and Adolescent Psychiatry, 34(7), 946-54.
10. Cahill, L., Haier, R.J., White, N.S., et al. (2001). Sex-related difference in amygdala activity during emotionally influenced memory storage. Neurobiology of Learning and Memory, 75(1), 1-9.
11. Campbell, R., Elgar, K., Kuntsi, J., et al. (2002). The classification of 'fear' from faces is associated with face recognition skill in women. Neuropsychologia, 40(6), 575-84.
12. Davis, M. (1992). The role of the amygdala in fear and anxiety. Annual Review of Neuroscience, 15, 353-75.
13. De Bellis, M.D., Casey, B.J., Dahl, R.E., et al. (2000). A pilot study of amygdala volumes in pediatric generalized anxiety disorder. Biological Psychiatry, 48(1), 51-7.
14. Edelbrock, C., Costello, A.J., Dulcan, M.K., Kalas, R., Conover, N.C. (1985). Age-differences in the reliability of the psychiatric interview of the child. Child Development, 56(1), 265-275.
15. Else-Quest, N.M., Hyde, J.S., Goldsmith, H.H., Van Hulle, C.A. (2006). Gender differences in temperament: A meta-analysis. Psychological Bulletin, 132(1), 33-72.
16. Fales, C.L., Barch, D.M., Rundle, M.A., et al. (2009). Antidepressant treatment normalizes hypoactivity in dorsolateral prefrontal cortex during emotional interference processing in major depression. Journal of Affective Disorders, 112(1-3), 206-11.
17. Frodl, T., Meisenzahl, E.M., Zetzsche, T., et al. (2003). Larger amygdala volumes in first depressive episode as compared to recurrent major depression and healthy control subjects. Biological Psychiatry, 53(4), 338-344.
18. Gard, M.G., Kring, A.M. (2007). Sex differences in the time course of emotion. Emotion, 7(2), 429.
19. Giedd, J.N., Castellanos, F.X., Rajapakse, J.C., Vaituzis, A.C., Rapoport, J.L. (1997). Sexual dimorphism of the developing human brain. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 21(8), 1185-201.
20. Giedd, J.N., Snell, J.W., Lange, N., et al. (1996). Quantitative magnetic resonance imaging of human brain development: Ages 4-18. Cerebral Cortex, 6(4), 551-60.
21. Goldstein, J.M., Seidman, L.J., Horton, N.J., et al. (2001). Normal sexual dimorphism of the adult human brain assessed by in vivo magnetic resonance imaging. Cerebral Cortex, 11(6), 490-7.
22. Good, C.D., Johnsrude, I., Ashburner, J., Henson, R.N.A., Friston, K.J., Frackowiak, R.S.J. (2001). Cerebral asymmetry and the effects of sex and handedness on brain structure: A voxel-based morphometric analysis of 465 normal adult human brains. NeuroImage, 14(3), 685-700.
23. Good, C.D., Lawrence, K., Thomas, N.S., et al. (2003). Dosage-sensitive X-linked locus influences the development of amygdala and orbitofrontal cortex, and fear recognition in humans. Brain, 126, 2431-46.
24. Gottesman, I.I., Gould, T.D. (2003). The endophenotype concept in psychiatry: Etymology and strategic intentions. American Journal of Psychiatry, 160(4), 636-45.
25. Hariri, A.R., Drabant, E.M., Munoz, K.E., et al. (2005). A susceptibility gene for affective disorders and the response of the human amygdala. Archives of General Psychiatry, 62(2), 146-52.
26. Hollingshead, A. (1975). Four Factor Index of Social Skills. New Haven: Yale.
27. Kagan, J., Reznick, J.S., Snidman, N. (1988). Biological bases of childhood shyness. Science, 240(4849), 167-71.
28. Khan, A.A., Jacobson, K.C., Gardner, C.O., Prescott, C.A., Kendler, K.S. (2005). Personality and comorbidity of common psychiatric disorders. British Journal of Psychiatry, 186, 190-6.
29. Lanteaume, L., Khalfa, S., Regis, J., Marquis, P., Chauvel, P., Bartolomei, F. (2007). Emotion induction after direct intracerebral stimulations of human amygdala. Cerebral Cortex, 17(6), 1307-13.
30. Lesch, K.P., Bengel, D., Heils, A., et al. (1996). Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science, 274(5292), 1527-31.
31. Lewinsohn, P.M., Zinbarg, R., Seeley, J.R., Lewinsohn, M., Sack, W.H. (1997). Lifetime comorbidity among anxiety disorders and between anxiety disorders and other mental disorders in adolescents. Journal of Anxiety Disorders, 11(4), 377-94.
32. Lindgren, S., Koeppl, G. (1987). Assessing Child Behavior Problems in a Medical Setting: Development of the Pediatric Behavior Scale. Greenwich, CT: JAI Press.
33. Machado, C.J., Bachevalier, J. (2008). Behavioral and hormonal reactivity to threat: Effects of selective amygdala, hippocampal or orbital frontal lesions in monkeys. Psychoneuroendocrinology, 33(7), 926-41.
34. Magnotta, V.A., Harris, G., Andreasen, N.C., O'Leary, D.A., Yuh, W.T.C., Heckel, D. (2002). Structural MR image processing using the BRAIN2 toolbox. Computerized Medical Imaging and Graphics, 26(4), 251-64.
35. Mai, J.K., Assheuer, J., Paxinos, G. (2007). Atlas of the Human Brain, 3rd edn. New York: Academic Press.
36. McCarthy, A.M., Lindgren, S., Mengeling, M.A., Tsalikian, E., Engvall, J.C. (2002). Effects of diabetes on learning in children. Pediatrics, 109(1), e9 p1-p10.
37. McEwen, B.S. (2003). Mood disorders and allostatic load. Biological Psychiatry, 54(3), 200-7.
38. McManis, M.H., Bradley, M.M., Berg, W.K., Cuthbert, B.N., Lang, P.J. (2001). Emotional reactions in children: Verbal, physiological, and behavioral responses to affective pictures. Psychophysiology, 38(2), 222.
39. Morris, J.S., Frith, C.D., Perrett, D.I., et al. (1996). A differential neural response in the human amygdala to fearful and happy facial expressions. Nature, 383(6603), 812-5.
40. Munn, M.A., Alexopoulos, J., Nishino, T., et al. (2007). Amygdala volume analysis in female twins with major depression. Biological Psychiatry, 62(5), 415-22.
41. Neale, M.C., Kendler, K.S. (1995). Models of comorbidity for multifactorial disorders. American Journal of Human Genetics, 57(4), 935-53.
42. Nestler, E.J., Barrot, M., DiLeone, R.J., Eisch, A.J., Gold, S.J., Monteggia, L.M. (2002). Neurobiology of depression. Neuron, 34(1), 13-25.
43. Nopoulos, P., Langbehn, D.R., Canady, J., Magnotta, V., Richman, L. (2007). Abnormal brain structure in children with isolated clefts of the lip or palate. Archives of Pediatrics & Adolescent Medicine, 161(8), 753-8.
44. Ollendick, T.H., Yang, B., Dong, Q., Xia, Y., Lin, L. (1995). Perceptions of fear in other children and adolescents: The role of gender and friendship status. Journal of Abnormal Child Psychology, 23(4), 439.
45. Pezawas, L., Meyer-Lindenberg, A., Drabant, E.M., et al. (2005). 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. Nature Neuroscience, 8(6), 828-34.
46. Pini, S., Cassano, G.B., Simonini, E., Savino, M., Russo, A., Montgomery, S.A. (1997). Prevalence of anxiety disorders comorbidity in bipolar depression, unipolar depression and dysthymia. Journal of Affective Disorders, 42(2-3), 145-53.
47. Roy, A.K., Vasa, R.A., Bruck, M., et al. (2008). Attention bias toward threat in pediatric anxiety disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 47(10), 1189-96.
48. Saudou, F., Amara, D.A., Dierich, A., et al. (1994). Enhanced aggressive behavior in mice lacking 5-HT1B receptor. Science, 265(5180), 1875-8.
49. Smider, N.A., Essex, M.J., Kalin, N.H., et al. (2002). Salivary cortisol as a predictor of socioemotional adjustment during kindergarten: A prospective study. Child Development, 73(1), 75-92.
50. Strauss, R.P., Broder, H. (1993). Children with cleft-lip palate and mentalretardation - a subpopulation of cleft-craniofacial team patients. Cleft Palate-Craniofacial Journal, 30(6), 548-56.
51. Tavares, J.V.T., Clark, L., Furey, M.L., Williams, G.B., Sahakian, B.J., Drevets, W.C. (2008). Neural basis of abnormal response to negative feedback in unmedicated mood disorders. NeuroImage, 42(3), 1118-26.
52. Tebartz van Elst, L., Woermann, F.G., Lemieux, L., Trimble, M.R. (1999). Amygdala enlargement in dysthymia-a volumetric study of patients with temporal lobe epilepsy. Biological Psychiatry, 46(12), 1614-23.
53. Tranel, D., Bechara, A. (2009). Sex-related functional asymmetry of the amygdala: Preliminary evidence using a case-matched lesion approach. Neurocase, 15(3), 217-34.
54. Tranel, D., Gullickson, G., Koch, M., Adolphs, R. (2006). Altered experience of emotion following bilateral amygdala damage. Cognitive Neuropsychiatry, 11(3), 219-32.
55. van Elst, L.T., Woermann, F., Lemieux, L., Trimble, M.R. (2000). Increased amygdala volumes in female and depressed humans. A quantitative magnetic resonance imaging study. Neuroscience Letters, 281(2-3), 103-6.
56. Verhulst, F.C., Vanderende, J. (1992). Agreement between parents reports and adolescents self-reports of problem behavior. Journal of Child Psychology and Psychiatry and Allied Disciplines, 33(6), 1011-23.
57. Vyas, A., Mitra, R., Chattarji, S. (2003). Enhanced anxiety and hypertrophy in basolateral amygdala neurons mowing chronic stress in rats. Amygdala in Brain Function: Bacic and Clinical Approaches, 985, 554-5.
58. Wechsler, D. (1991). Wechsler Intelligence Scale for Children, 3rd edn. San Antonio, TX: The Psychological Corporation.
59. Woods, R.P., Cherry, S.R., Mazziotta, J.C. (1992). Rapid automated algorithm for aligning and reslicing pet images. Journal of Computer Assisted Tomography, 16(4), 620-33.
60. Zahn-Waxler, C., Shirtcliff, E.A., Marceau, K. (2008). Disorders of childhood and adolescence: Gender and psychopathology. Annual Review of Clinical Psychology, 4, 275-303.