Novel antiviral benzofuran-transition metal complexes

European Journal of Medicinal Chemistry

Volumn 45, Issue 7, 2010, Pages 3035-3046

  Galal, Shadia A ^a   Abd El All, Amira S ^a   Hegab, Khaled H ^a   Magd El Din, Asmaa A ^a   Youssef, Nabil S ^a   El Diwani, Hoda I ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Antiviral activity; Benzofurans; HCV NS3 4A protease inhibitor activity; HIV and HIV 1 RT inhibitory activity; Transition metal complexes

Indexed keywords

( 1H BENZO[D]IMIDAZOL 2 YL]METHANAMINE; ( 2 ( 1H BENZO[D]IMIDAZOL 2 YL) 4 ( 6 HYDROXY 4,7 DIMETHOXYBENZOFURAN 5 CARBONYL) 1H PYRROL 1 YL)COPPER; ( 2 ( 1H BENZO[D]IMIDAZOL 2 YL) 4 ( 6 HYDROXY 4,7 DIMETHOXYBENZOFURAN 5 CARBONYL) 1H PYRROL 1 YL)IRON; ( 2 ( 1H BENZO[D]IMIDAZOL 2 YL) 4 ( 6 HYDROXY 4,7 DIMETHOXYBENZOFURAN 5 CARBONYL) 1H PYRROL 1 YL)ZINC; ( 3 ( 6 HYDROXY 4,7 DIMETHOXYBENZOFURAN 5 CARBONYL) 8 OXO 8H PYRIMIDO[ 1,6 A]PYRIMIDIN 6 YLOXY)COPPER; ( 3 ( 6 HYDROXY 4,7 DIMETHOXYBENZOFURAN 5 CARBONYL) 8 OXO 8H PYRIMIDO[ 1,6 A]PYRIMIDIN 6 YLOXY)IRON; ( 5 ( 1H BENZO[D]IMIDAZOL 2 YL) 1H PYRROL 3 YL)( 6 HYDROXY 4,7 DIMETHOXYBENZOFURAN 5 YL)METHANONE; (3 ( 6 HYDROXY 4,7 DIMETHOXYBENZOFURAN 5 CARBONYL) 8 OXO 8H PYRIMIDO[ 1,6 A]PYRIMIDIN 6 YLOXY)LANTHANUM; 3 ( 6 HYDROXY 4,7 DIMETHOXYBENZOFURAN 5 CARBONYL) 6H PYRIMIDO[ 1,6 A]PYRIMIDINE 6,8 (7H)DIONE; 4 AMINO 2,6 DIHYDROXYPYRIMIDINE; 4,7 DIMETHOXY 5 OXO 5H FURO[ 3,2 G]CHROMENE 6 CARBALDEHYDE; ATEVIRDINE; BENZOFURAN DERIVATIVE; BIS( 2 ( 1H BENZO[D]IMIDAZOL 2 YL) 4 ( 6 HYDROXY 4,7 DIMETHOXYBENZOFURAN 5 CARBONYL) 1H PYRROL 1YL)LANTHANUM; BIS( 6 HYDROXY 4,7 DIMETHOXYBENZOFURAN 5 CARBONYL) 8 OXO 8H PYRIMIDO[ 1,6 A]PYRIMIDIN 6 YLOXY)COBALT; COPPER CHLORIDE; COPPER COMPLEX; FERRIC CHLORIDE; IMIDAZOLE DERIVATIVE; IRON DERIVATIVE; LANTHANUM CHLORIDE; METAL COMPLEX; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 4A; POTASSIUM HYDROXIDE; PROTEINASE INHIBITOR; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; TELAPREVIR; UNCLASSIFIED DRUG; ZINC CHLORIDE;

ANTIVIRAL ACTIVITY; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG INHIBITION; DRUG POTENCY; DRUG SYNTHESIS; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; LIVER CELL; RING OPENING; VIRUS REPLICATION;

EID: 77954349655     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.03.034     Document Type: Article

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