QSAR analysis of diaryl COX-2 inhibitors: Comparison of feature selection and train-test data selection methods

European Journal of Medicinal Chemistry

Volumn 45, Issue 7, 2010, Pages 2753-2760

  Soltani, Somaieh ^a   Abolhasani, Hoda ^b   Zarghi, Afshin ^c   Jouyban, Abolghasem ^d  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

COX 2 selective inhibition; Feature selection; QSAR; Test train selection

Indexed keywords

4 BENZYLIDENEAMINOBENZENESULFONAMIDE; 4 PHENYLIMINOMETHYLBENZENESULFONAMIDE; CYCLOOXYGENASE 2 INHIBITOR; PHENYL AZO BENZEN SULFONAMIDE; RESVERATROL; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; CORRELATION COEFFICIENT; DRUG STRUCTURE; IC 50; PARTIAL LEAST SQUARES REGRESSION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SAMPLING; VALIDATION STUDY;

CLUSTER ANALYSIS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; LEAST-SQUARES ANALYSIS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; REGRESSION ANALYSIS; REPRODUCIBILITY OF RESULTS; STILBENES;

EID: 77954348985     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.02.055     Document Type: Article

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