Selective COX-2 inhibitors. Part 1: Synthesis and biological evaluation of phenylazobenzenesulfonamides

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 17, 2006, Pages 4440-4443

  Tsai, Wei Jern ^a   Shiao, Young Ji ^a   Lin, Shwu Jiuan ^b   Chiou, Wen Fei ^a   Lin, Lie Chwen ^a   Yang, Tsang Hsiung ^b   Teng, Che Ming ^c   Wu, Tain Shung ^a   Yang, Li Ming ^a,b  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Anti inflammatory; Isosterism; Phenylazobenzenesulfonamide; Resveratrol; SAR; Selective COX 2 inhibitors

Indexed keywords

4 (4 AMINO 2 METHYLSULFANYLPHENYLAZO)BENZENESULFONAMIDE; BENZENESULFONAMIDE DERIVATIVE; CYCLOOXYGENASE 2 INHIBITOR; PHENYLAZOBENZENESULFONAMIDE DERIVATIVE; PROSTAGLANDIN SYNTHASE; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD; CELL ASSAY; CONTROLLED STUDY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ASSAY; ENZYME INHIBITION; HUMAN; STRUCTURE ACTIVITY RELATION;

AZO COMPOUNDS; BLOOD CELLS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; HUMANS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

OVIS;

EID: 33746380540     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.06.036     Document Type: Article

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