Selective COX-2 inhibitors. Part 2: Synthesis and biological evaluation of 4-benzylideneamino- and 4-phenyliminomethyl-benzenesulfonamides

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 5, 2008, Pages 2697-2706

  Lin, Shwu Jiuan ^a   Tsai, Wei Jern ^b   Chiou, Wen Fei ^b   Yang, Tsang Hsiung ^a   Yang, Li Ming ^a,b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

Author keywords

Anti inflammatory; Benzenesulfonamide; Benzylideneamino; Isosterism; Phenyliminomethyl; Resveratrol; SAR; Selective COX 2 inhibitors

Indexed keywords

4 (3 CARBOXY 4 HYDROXY BENZYLIDENEAMINO)BENZENESULFONAMIDE; 4 BENZYLIDENEAMINO BENZENESULFONAMIDE DERIVATIVE; 4 PHENYLIMINOMETHYL BENZENESULFONAMIDE DERIVATIVE; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

AMINATION; BENZYLIDENE COMPOUNDS; BLOOD PLATELETS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; HUMANS; IMINES; METHYLATION; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

EID: 40749088834     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2007.11.033     Document Type: Article

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