Metabolic deglucuronidation and demethylation of estrogen conjugates as a source of parent estrogens and catecholestrogen metabolites in Syrian hamster kidney, a target organ of estrogen-induced tumorigenesis

Toxicology and Applied Pharmacology

Volumn 136, Issue 1, 1996, Pages 186-193

  Zhu, Bao Ting ^a,c   Evaristus, Enongene N ^b,c   Antoniak, Sandra K ^c   Sarabia, Stephen F ^c   Ricci, Mary Jo ^c   Liehr, Joachim G ^c  

^a RUTGERS UNIVERSITY   (United States)

^b TEXAS SOUTHERN UNIVERSITY   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRICETINAE; MESOCRICETUS AURATUS;

2 HYDROXYESTRADIOL; 2 METHOXYESTRADIOL; 4 HYDROXYESTRADIOL; 4 METHOXYESTRADIOL; CATECHOL ESTROGEN; DRUG METABOLITE; ESTRADIOL; ESTRIOL; ESTROGEN; KIDNEY ENZYME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CONTROLLED STUDY; DEMETHYLATION; DRUG CONJUGATION; DRUG METABOLISM; KIDNEY; LIVER; MALE; NONHUMAN; SYRIAN HAMSTER;

ANIMALS; CELL FRACTIONATION; CRICETINAE; ESTRADIOL; ESTROGENS, CONJUGATED (USP); ESTRONE; GLUCURONIDASE; KIDNEY; KIDNEY NEOPLASMS; LIVER; LYSOSOMES; MALE; MESOCRICETUS; METHYLATION; OXIDOREDUCTASES, N-DEMETHYLATING;

EID: 0030030930     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1996.0023     Document Type: Article

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