Novel pectin-4-aminothiophenole conjugate microparticles for colon-specific drug delivery

Journal of Controlled Release

Volumn 145, Issue 3, 2010, Pages 240-246

  Perera, Glen ^a   Barthelmes, Jan ^a   Bernkop Schnürch, Andreas ^a  

^a UNIVERSITY OF INNSBRUCK   (Austria)

Author keywords

Colon specific drug delivery; Metronidazole; Microparticles; Pectin; Spray drying

Indexed keywords

4-AMINOTHIOPHENOL; CACO-2 CELLS; CELL VIABILITY; COLON-SPECIFIC DRUG DELIVERY; DRUG LOAD; IN-VITRO; LOW TOXICITY; MEAN DIAMETER; METRONIDAZOLE; MICRO-PARTICLES; MODIFIED PECTIN; PECTINOLYTIC ENZYME; RELEASE BEHAVIORS;

DRUG DELIVERY;

DRYING;

CHITOSAN; DRUG CARRIER; METRONIDAZOLE; PECTIN; PECTIN 4 AMINOTHIOPHENOLE; THIOPHENOL DERIVATIVE; UNCLASSIFIED DRUG; 4-AMINOTHIOPHENOL; ANILINE DERIVATIVE; ANTIINFECTIVE AGENT; THIOL DERIVATIVE;

ARTICLE; CELL STRAIN CACO 2; CELL VIABILITY; COLON; CONJUGATE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; PARTICLE SIZE; PRIORITY JOURNAL; CACO 2 CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; METABOLISM; PROCEDURES; SYNTHESIS;

ANILINE COMPOUNDS; ANTI-INFECTIVE AGENTS; CACO-2 CELLS; CELL SURVIVAL; COLON; DRUG DELIVERY SYSTEMS; HUMANS; METRONIDAZOLE; PARTICLE SIZE; PECTINS; SULFHYDRYL COMPOUNDS;

EID: 77954311428     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.04.024     Document Type: Article

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