Observations in simultaneous microencapsulation of 5-fluorouracil and leucovorin for combined pH-dependent release

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 59, Issue 2, 2005, Pages 367-371

  Lamprecht, Alf ^a   Yamamoto, Hiromitsu ^a   Takeuchi, Hirofumi ^a   Kawashima, Yoshiaki ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

5 Fluorouracil; Colon delivery; Colorectal cancer; Leucovorin; Microspheres

Indexed keywords

EUDRAGIT P 4135 F; EUDRAGIT RS; FLUOROURACIL; FOLINIC ACID; MICROSPHERE; OIL; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; CRYSTAL; DRUG RELEASE; EMULSION; LIPOPHILICITY; MICROENCAPSULATION; PARTICLE SIZE; PH MEASUREMENT; SCANNING ELECTRON MICROSCOPY;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; FLUOROURACIL; HYDROGEN-ION CONCENTRATION; LEUCOVORIN; MICROSPHERES;

EID: 12344281713     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2004.09.005     Document Type: Article

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