Locust flight activity as a model for hormonal regulation of lipid mobilization and transport

Journal of Insect Physiology

Volumn 56, Issue 8, 2010, Pages 844-853

  Van der Horst, Dick J ^a   Rodenburg, Kees W ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

AKH; Apolipophorin III; Diacylglycerol; Fat body lipase; Fatty acid binding protein; Lipid transport; Lipophorin; Lipoprotein receptor; Neuropeptide; Signal transduction

Indexed keywords

ADIPOKINETIC HORMONE (LOCUST); APOLIPOPHORIN III; APOLIPOPROTEIN; INSECT HORMONE;

BIOCHEMISTRY; ENZYME ACTIVITY; FATTY ACID; FLIGHT ACTIVITY; HORMONE; LIPID; LOCUST; METABOLISM; PEPTIDE; PEST SPECIES; PHYSIOLOGICAL RESPONSE;

ANIMAL; ANIMAL MODEL; ENERGY METABOLISM; FLYING; GRASSHOPPER; LIPID METABOLISM; METABOLISM; METHODOLOGY; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; APOLIPOPROTEINS; BIOLOGICAL TRANSPORT; ENERGY METABOLISM; FLIGHT, ANIMAL; GRASSHOPPERS; INSECT HORMONES; LIPID MOBILIZATION; MODELS, ANIMAL; PHYSIOLOGY; SIGNAL TRANSDUCTION;

HEXAPODA; MAMMALIA;

EID: 77954309787     PISSN: 00221910     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinsphys.2010.02.015     Document Type: Review

References (130)

1. Adams M.D., et al. The genomic sequence of Drosophila melanogaster. Science 2000, 24:2185-2195.
2. Arrese E.L., Rivera L., Hamada M., Mirza S., Hartson S.D., Weintraub S., Soulages J.L. Function and structure of lipid storage droplet protein 1 studied in lipoprotein complexes. Archives of Biochemistry and Biophysics 2008, 473:42-47.
3. Arrese E.L., Mirza S., Rivera L., Howard A.D., Chetty P.S., Soulages J.L. Expression of lipid storage droplet protein-1 may define the role of AKH as a lipid mobilizing hormone in Manduca sexta. Insect Biochemistry and Molecular Biology 2008, 38:993-1000.
4. Ayali A., Pener M.P., Girardie J. Comparative study of neuropeptides from the corpora cardiaca of solitary and gregarious Locusta. Archives of Insect Biochemistry and Physiology 1996, 31:439-450.
5. Babin P.J., Bogerd J., Kooiman F.P., Van Marrewijk W.J.A., Van der Horst D.J. Apolipophorin II/I, apolipoprotein B, vitellogenin, and microsomal triglyceride transfer protein genes are derived from a common ancestor. Journal of Molecular Evolution 1999, 49:150-160.
6. Baggerman G., Huybrechts J., Clynen E., Hens K., Harthoorn L., Van der Horst D., Poulos C., De Loof A., Schoofs L. New insights in adipokinetic hormone (AKH) precursor processing in Locusta migratoria obtained by capillary liquid chromatography-tandem mass spectrometry. Peptides 2002, 23:635-644.
7. Baggerman G., Verleyen P., Clynen E., Huybrechts J., De Loof A., Schoofs L. Peptidomics. Journal of Chromatography B 2004, 803:3-16.
8. Beenakkers A.M.Th. The influence of corpus allatum and corpus cardiacum on lipid metabolism in Locusta migratoria. General and Comparative Endocrinology 1969, 13:492.
9. Beenakkers A.M.Th., Van der Horst D.J., Van Marrewijk W.J.A. Role of lipids in energy metabolism. Energy Metabolism and Its Regulation in Insects 1981, 53-100. Plenum Press, New York. R.G.H. Downer (Ed.).
10. Beenakkers A.M.Th., Van der Horst D.J., Van Marrewijk W.J.A. Metabolism during locust flight. Comparative Biochemistry and Physiology B 1981, 69:315-321.
11. Beenakkers A.M.Th., Van der Horst D.J., Van Marrewijk W.J.A. Insect flight muscle metabolism. Insect Biochemistry 1984, 14:243-260.
12. Beenakkers A.M.Th., Van der Horst D.J., Van Marrewijk W.J.A. Insect lipids and lipoproteins, and their role in physiological processes. Progress in Lipid Research 1985, 24:19-67.
13. Beenakkers A.M.Th., Van der Horst D.J., Van Marrewijk W.J.A. Biochemical processes directed to flight muscle metabolism. Comprehensive Insect Physiology, Biochemistry and Pharmacology 1985, vol. 10:451-486. Pergamon Press, Oxford.
14. Beenakkers A.M.Th., Chino H., Law J.H. Lipophorin nomenclature. Insect Biochemistry 1988, 18:1-2.
15. Blacklock B.J., Ryan R.O. Hemolymph lipid transport. Insect Biochemistry and Molecular Biology 1994, 24:855-873.
16. Bogerd J., Kooiman F.P., Pijnenburg M.A.P., Hekking L.H.P., Oudejans R.C.H.M., Van der Horst D.J. Molecular cloning of three distinct cDNAs, each encoding a different adipokinetic hormone precursor, of the migratory locust, Locusta migratoria. Differential expression of the distinct adipokinetic hormone precursor genes during flight activity. Journal of Biological Chemistry 1995, 270:23038-23043.
17. Bogerd J., Babin P.J., Kooiman F.P., André M., Ballagny C., Van Marrewijk W.J.A., Van der Horst D.J. Molecular characterization and gene expression in the eye of the apolipophorin II/I precursor from Locusta migratoria. Journal of Comparative Neurology 2000, 427:546-558.
18. Breiter D.B., Kanost M.R., Benning M.M., Wesenberg G., Law J.H., Wells M.A., Rayment I., Holden H.M. Molecular structure of an apolipoprotein determined at 2.5-Å resolution. Biochemistry 1991, 30:603-608.
19. Candy D.J., Becker A., Wegener G. Coordination and integration of metabolism in insect flight. Comparative Biochemistry and Physiology B 1997, 117:497-512.
20. Chino H. Physiological significance of lipid transport by lipophorin for long-distance flight in insects. Comparative Biochemistry and Physiology B 1997, 117:455-461.
21. Chino H., Kitazawa K. Diacylglycerol-carrying lipoprotein of hemolymph of the locust and some insects. Journal of Lipid Research 1981, 22:1042-1052.
22. Chiu M.H., Wan C.-P.L., Weers P.M.M., Prenner E.J. Apolipophorin III interaction with model membranes composed of phosphatidylcholine and sphingomyelin using differential scanning calorimetry. Biochimica et Biophysica Acta 2009, 1788:2160-2168.
23. Clynen E., Baggerman G., Veelaert D., Cerstiaens A., Van der Horst D., Harthoorn L., Derua R., Waelkens E., De Loof A., Schoofs L. Peptidomics of the pars intercerebralis-corpus cardiacum complex of the migratory locust, Locusta migratoria. European Journal of Biochemistry 2001, 268:1929-1939.
24. Clynen E., Stubbe D., De Loof A., Schoofs L. Peptide differential display: a novel approach for phase transition in locusts. Comparative Biochemistry and Physiology B 2002, 132:107-115.
25. Clynen E., Huybrechts J., De Loof A., Schoofs L. Mass spectrometric analysis of the perisympathetic organs in locusts: identification of novel periviscerokinins. Biochemical and Biophysical Research Communications 2003, 300:422-428.
26. Clynen E., Huybrechts J., Verleyen P., De Loof A., Schoofs L. Annotation of novel neuropeptide precursors in the migratory locust based on transcript screening of a public EST database and mass spectrometry. BMC Genomics 2006, 7:201.
27. Clynen E., Schoofs L. Peptidomic survey of the locust neuroendocrine system. Insect Biochemistry and Molecular Biology 2009, 39:491-507.
28. Dantuma N.P., Pijnenburg M.A.P., Diederen J.H.B., Van der Horst D.J. Developmental down-regulation of receptor-mediated endocytosis of an insect lipoprotein. Journal of Lipid Research 1997, 38:254-265.
29. Dantuma N.P., Pijnenburg M.A.P., Diederen J.H.B., Van der Horst D.J. Multiple interactions between insect lipoproteins and fat body cells: extracellular trapping and endocytic trafficking. Journal of Lipid Research 1998, 39:1877-1888.
30. Dantuma N.P., Potters M., De Winther M.P.J., Tensen C.P., Kooiman F.P., Bogerd J., Van der Horst D.J. An insect homolog of the vertebrate very low density lipoprotein receptor mediates endocytosis of lipophorins. Journal of Lipid Research 1999, 40:973-978.
31. Demel R.A., Van Doorn J.M., Van der Horst D.J. Insect apolipophorin III: interaction of locust apolipophorin III with diacylglycerol. Biochimica et Biophysica Acta 1992, 1124:151-158.
32. De Winther M.P.J., Weers P.M.M., Bogerd J., Van der Horst D.J. Apolipophorin III levels in Locusta migratoria. Developmental regulation of gene expression and hemolymph protein concentration. Journal of Insect Physiology 1996, 42:1047-1052.
33. Diederen J.H.B., Oudejans R.C.H.M., Harthoorn L.F., Van der Horst D.J. Cell biology of the adipokinetic hormone-producing neurosecretory cells in the locust corpus cardiacum. Microscopy Research and Technique 2002, 56:227-236.
34. Downer R.G.H., Chino H. Turnover of protein and diacylglycerol components of lipophorin in insect haemolymph. Insect Biochemistry 1985, 15:627-630.
35. Fan D., Zheng Y., Yang D., Wang J. NMR solution structure and dynamics of an exchangeable apolipoprotein, Locusta migratoria apolipophorin III. Journal of Biological Chemistry 2003, 278:21212-21220.
36. Gäde G. The adipokinetic hormone/red pigment-concentrating hormone peptide family: structures, interrelationships and functions. Journal of Insect Physiology 1990, 36:1-12.
37. Gäde G. The explosion of structural information on insect neuropeptides. Progress in the Chemistry of Organic Natural Products 1997, 71:1-128.
38. Gäde G., Goldsworthy G.J., Schaffer M.H., Cook J.C., Rinehart K.L. Sequence analyses of adipokinetic hormone II from corpora cardiaca of Schistocerca nitans. Schistocerca gregaria, and Locusta migratoria by fast atom bombardment mass spectrometry. Biochemical and Biophysical Research Communications 1986, 134:723-730.
39. Goldsworthy G.J. The endocrine control of flight metabolism in locusts. Advances in Insect Physiology 1983, vol. 17:149-204. Academic Press, London.
40. Goldsworthy G.J., Mordue W., Guthkelch J. Studies on insect adipokinetic hormones. General and Comparative Endocrinology 1972, 18:545-551.
41. Goldsworthy G.J., Mordue W. Neurosecretory hormones in insects. Journal of Endocrinology 1974, 60:529-558.
42. Grönke S., Beller M., Fellert S., Ramakrishnan H., Jäckle H., Kühnlein R.P. Control of fat storage by a Drosophila PAT domain protein. Current Biology 2003, 13:603-606.
43. Grönke S., Mildner A., Fellert S., Tennagels N., Petry S., Müller G., Jäckle H., Kühnlein R.P. Brummer lipase is an evolutionary conserved fat storage regulator in Drosophila. Cell Metabolism 2005, 1:323-330.
44. Grönke S., Müller G., Hirsch J., Fellert S., Andreou A., Haase T., Jäckle H., Kühnlein R.P. Dual lipolytic control of body fat storage and mobilization in Drosophila. PLoS Biology 2007, 5(6):e137. 10.1371/journal.pbio.0050137.
45. Guglielmo C.G., Haunerland N.H., Hochachka P.W., Williams T.D. Seasonal dynamics of flight muscle fatty acid binding protein and catabolic enzymes in a migratory shorebird. American Journal of Physiology 2002, 282:R1405-R1413.
46. Haunerland N.H., Chisholm J.M. Fatty-acid binding protein in flight muscle of the locust. Schistocerca gregaria. Biochimica et Biophysica Acta 1990, 1047:233-238.
47. Haunerland N.H., Andolfatto P., Chisholm J.M., Wang Z., Chen X. Fatty-acid-binding protein in locust flight muscle. Developmental changes of expression, concentration and intracellular distribution. European Journal of Biochemistry 1992, 210:1045-1051.
48. Hekimi S., O'Shea M. Identification, and purification of two precursors of the insect adipokinetic hormone. Journal of Neuroscience 1987, 7:2773-2784.
49. Hiraoka T., Hayakawa Y. Inhibition of diacylglycerol uptake from the fat body by a monoclonal antibody against apolipophorin II in Locusta migratoria. Insect Biochemistry 1990, 20:793-799.
50. Hirayama Y., Chino H. A new method for determining lipase activity in locust fat body. Insect Biochemistry 1987, 17:85-88.
51. Hoste B., Simpson S.J., Tanaka S., Zhu D.H., De Loof A., Breuer M. Effects of [His7]-corazonin on the phase state of isolated-reared (solitarious) desert locusts, Schistocerca gregaria. Journal of Insect Physiology 2002, 48:981-990.
52. Jutsum A.R., Goldsworthy G.J. Fuels for flight in Locusta. Journal of Insect Physiology 1976, 22:243-249.
53. Kang L., Chen X., Zhou Y., Liu B., Zheng W., Li R., Wang J., Yu J. The analysis of large-scale gene expression correlated to the phase changes of the migratory locust. Proceedings of the National Academy of Sciences of the United States of America 2004, 101:17611-17615.
54. Krogh A., Weis-Fogh T. The respiratory exchange of the desert locust (Schistocerca gregaria) before, during and after flight. Journal of Experimental Biology 1951, 28:344-357.
55. Lima M. Locust plagues, climate variation, and the rhythms of nature. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:15972-15973.
56. Lok C.M., Van der Horst D.J. Chiral 1,2-diacylglycerols in the haemolymph of the locust, Locusta migratoria. Biochimica et Biophysica Acta 1980, 618:80-87.
57. Lücke C., Qiao Y., Van Moerkerk H.T.B., Veerkamp J.H., Hamilton J.A. Fatty- acid-binding protein from the flight muscle of Locusta migratoria: evolutionary variations in fatty acid binding. Biochemistry 2006, 45:6296-6305.
58. Maatman R.G.H.J., Degano M., Van Moerkerk H.T.B., Van Marrewijk W.J.A., Van der Horst D.J., Sacchettini J.C., Veerkamp J.H. Primary structure and binding characteristics of locust and human muscle fatty-acid-binding proteins. European Journal of Biochemistry 1994, 221:801-810.
59. Mayer R.J., Candy D.J. Control of haemolymph lipid concentration during locust flight: an adipokinetic hormone from the corpora cardiaca. Journal of Insect Physiology 1969, 15:611-620.
60. Miura S., Gan J.W., Brzostowski J., Parisi M.J., Schultz C.J., Londos C., Oliver B., Kimmel A.R. Functional conservation for lipid storage droplet association among Perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, Drosophila, and Dictyostelium. Journal of Biological Chemistry 2002, 277:32253-32257.
61. Mordue (Luntz) A.J., Evans K.A., Charlet M. Azadirachtin, ecdysteroids and ecdysis in Locusta migratoria. Comparative Biochemistry and Physiology C 1986, 85:297-301.
62. Mwangi R.W., Goldsworthy G.J. Diglyceride-transporting lipoproteins in Locusta. Journal of Comparative Physiology 1977, 114:177-190.
63. Mwangi R.W., Goldsworthy G.J. Diacylglycerol-transporting lipoproteins and flight in Locusta. Journal of Insect Physiology 1981, 27:47-50.
64. Narayanaswami V., Ryan R.O. Molecular basis of exchangeable apolipoprotein function. Biochimica et Biophysica Acta 2000, 1483:15-36.
65. Narayanaswami V., Kiss R.S., Weers P.M.M. The helix bundle: A reversible lipid motif. Comparative Biochemistry and Physiology A 2010, 155:123-133.
66. Ogoyi D.O., Osir E.O., Olembo N.K. Fat body triacylglycerol lipase in solitary and gregarious phases of Schistocerca gregaria (Forskal) (Orthoptera: Acrididae). Comparative Biochemistry and Physiology B 1998, 119:163-167.
67. Oudejans R.C.H.M., Kooiman F.P., Heerma W., Versluis C., Slotboom A.J., Beenakkers A.M.T. Isolation and structure elucidation of a novel adipokinetic hormone (Lom-AKH-III) from the glandular lobes of the corpus cardiacum of the migratory locust, Locusta migratoria. European Journal of Biochemistry 1991, 195:351-359.
68. Oudejans R.C.H.M., Mes T.H.M., Kooiman F.P., Van der Horst D.J. Adipokinetic peptide hormone content and biosynthesis during locust development. Peptides 1993, 14:877-881.
69. Oudejans R.C.H.M., Vroemen S.F., Jansen R.F.R., Van der Horst D.J. Locust adipokinetic hormones: carrier-independent transport and differential inactivation at physiological concentrations during rest and flight. Proceedings of the National Academy of Sciences of the United States of America 1996, 93:8654-8659.
70. Pener M.P. Hormonal effects on flight and migration. Comprehensive Insect Physiology, Biochemistry and Pharmacology 1985, vol. 8:491-550. Pergamon Press, Oxford.
71. Pener M.P. Locust phase polymorphism and its endocrine relations. Advances in Insect Physiology 1991, 23:1-79.
72. Pener M.P., Orshan L., De Wilde J. Precocene II causes atrophy of corpora allata in Locusta migratoria. Nature 1978, 272:350-353.
73. Pener M.P., Van den Broek A.Th.M., Van Marrewijk W.J.A., Van Doorn J.M., Van der Horst D.J., Beenakkers A.M.Th. Development of imaginal competence to adipokinetic hormone in Locusta: Lipid and carbohydrate levels, and glycogen phosphorylase activity in azadirachtin-induced over-aged nymphs. Comparative Biochemistry and Physiology B 1989, 94:293-298.
74. Pener M.P., Yerushalmi Y. The physiology of locust phase polymorphism: an update. Journal of Insect Physiology 1998, 44:365-377.
75. Price H.M., Ryan R.O., Haunerland N.H. Primary structure of locust flight muscle fatty-acid binding protein. Archives of Biochemistry and Biophysics 1992, 297:285-290.
76. Qu H., Cui L., Rickers-Haunerland J., Haunerland N.H. Fatty acid-dependent expression of the muscle FABP gene-comparative analysis of gene control in functionally related, but evolutionary distant animal systems. Molecular and Cellular Biochemistry 2007, 299:45-53.
77. Rodenburg K.W., Van der Horst D.J. Lipoprotein-mediated lipid transport in insects: Analogy to the mammalian lipid carrier system and novel concepts for the functioning of LDL receptor family members. Biochimica et Biophysica Acta 2005, 10-29.
78. Roosendaal S.D., Kerver J., Schipper M., Rodenburg K.W., Van der Horst D.J. The complex of the insect LDL receptor homologue, LpR, and its lipoprotein ligand does not dissociate at endosomal conditions. FEBS Journal 2008, 275:1751-1766.
79. Roosendaal S.D., Van Doorn J.M., Valentijn K.M., Van der Horst D.J., Rodenburg K.W. Delipidation of insect lipoprotein, lipophorin, affects its binding to the lipophorin receptor, LpR: implications for the role of LpR-mediated endocytosis. Insect Biochemistry and Molecular Biology 2009, 39:135-144.
80. Ryan R.O. The dynamics of insect lipophorin metabolism. Journal of Lipid Research 1990, 31:1725-1739.
81. Ryan R.O. The structures of insect lipoproteins. Current Opinion in Structural Biology 1994, 4:499-506.
82. Ryan R.O., Van der Horst D.J. Lipid transport biochemistry and its role in energy production. Annual Review of Entomology 2000, 45:233-260.
83. Schoofs L., Veelaert D., Vanden Broeck J., De Loof A. Peptides in the locusts. Locusta migratoria and Schistocerca gregaria. Peptides 1997, 18:145-156.
84. Sieber K.-P., Rembold H. The effects of azadirachtin on the endocrine control of moulting in Locusta migratoria. Journal of Insect Physiology 1983, 29:523-527.
85. Siegert K., Morgan P.J., Mordue W. Primary structure of locust adipokinetic hormone II. Biological Chemistry Hoppe Seyler 1985, 366:723-727.
86. Smolenaars M.M.W., Kasperaitis M.A.M.S Richardson##P.E., Rodenburg K.W.S Van der Horst##D.J. Biosynthesis and secretion of insect lipoprotein: involvement of furin in cleavage of the apoB homolog, apolipophorin-II/I. Journal of Lipid Research 2005, 46:412-421.
87. Smolenaars M.M.W., Madsen O., Rodenburg K.W., Van der Horst D.J. Molecular diversity and evolution of the large lipid transfer protein superfamily. Journal of Lipid Research 2007, 48:489-502.
88. Stone J.V., Mordue W., Batley K.E., Morris H.R. Structure of locust adipokinetic hormone, a neurohormone that regulates lipid utilisation during flight. Nature 1976, 263:207-211.
89. Teixeira L., Rabouille C., Rorth P., Ephrussi A., Vanzo N.F. Drosophila Perilipin/ADRP homologue Lsd2 regulates lipid metabolism. Mechanisms of Development 2003, 120:1071-1081.
90. Tietz A., Weintraub H. The stereospecific structure of haemolymph and fat body 1,2-diacylglycerol from Locusta migratoria. Insect Biochemistry 1980, 10:61-63.
91. Valentijn, K.M., Koning, R., Derks, Y., Van Doorn, J.M., Van der Krift, T.P., Schouten, A., Koerten, H.K, Van der Horst, D.J., Gros, P., Koster, A.J., Rodenburg, K.W., 2004. Preliminary three-dimensional model of insect lipoprotein HDLp by using electron miscroscopy and X-ray crystallography. In: Anderson, M., Price, R., Hall, E., Clark, E., McKernan S. (Eds.), Proceedings of Microscopy and Microanalysis, vol. 10. Savannah, GA, USA, pp. 1514-1515.
92. Van Antwerpen R., Linnemans W.A.M., Van der Horst D.J., Beenakkers A.M.Th. Immunocytochemical localization of lipophorins in the flight muscles of the migratory locust (Locusta migratoria) at rest and during flight. Cell Tissue Research 1988, 252:661-668.
93. Van der Horst D.J. Lipid transport function of lipoproteins in flying insects. Biochimica et Biophysica Acta 1990, 1047:195-211.
94. Van der Horst D.J. Insect adipokinetic hormones: release and integration of flight energy metabolism. Comparative Biochemistry and Physiology B 2003, 136:217-226.
95. Van der Horst D.J., Baljet A.M.C., Beenakkers A.M., Van Handel Th.E. Turnover of locust haemolymph diglycerides during flight and rest. Insect Biochemistry 1978, 8:369-373.
96. Van der Horst D.J., Van Doorn J.M., Beenakkers A.M.Th. Effects of the adipokinetic hormone on the release and turnover of hemolymph diglycerides and on the function of the diglyceride-transporting lipoprotein system during locust flight. Insect Biochemistry 1979, 9:627-635.
97. Van der Horst D.J., Stoppie P., Huybrechts R., De Loof A., Beenakkers A.M.Th. Immunological relationships between diacylglycerol-transporting lipoproteins in the haemolymph of Locusta. Comparative Biochemistry and Physiology B 1981, 70:387-392.
98. Van der Horst D.J., Van Doorn J.M., De Keijzer A.N., Beenakkers A.M.Th. Interconversions of diacylglycerol-transporting lipoproteins in the haemolymph of Locusta migratoria. Insect Biochemistry 1981, 11:717-723.
99. 2. Insect Biochemistry 1984, 14:495-504.
100. Van der Horst D.J., Beenakkers A.M.Th., Van Doorn J.M., Gerritse K., Schulz T.K.F. Adipokinetic hormone-induced lipid mobilization and lipophorin interconversions in fifth instar larval locusts. Insect Biochemistry 1987, 17:799-808.
101. Van der Horst D.J., Ryan R.O., Van Heusden M.C., Schulz T.K.F., Van Doorn J.M., Law J.H., Beenakkers A.M.Th. An insect lipoprotein hybrid helps to define the role of apolipophorin III. Journal of Biological Chemistry 1988, 263:2027-2033.
102. Van der Horst D.J., Van Doorn J.M., Pener M.P., Van den Broek A.Th.M., Van Marrewijk W.J.A., Beenakkers A.M.Th. Development of imaginal competence to adipokinetic hormone in Locusta: Lipophorin conversions in precocene-induced adultiforms and in azadirachtin-induced over-aged nymphs. Comparative Biochemistry and Physiology B 1989, 92:133-136.
103. Van der Horst D.J., Weers P.M.M., Van Marrewijk W.J.A. Lipoproteins and lipid transport. Insect lipids: Chemistry, Biochemistry, and Biology 1993, 1-24. University of Nebraska Press, Lincoln NE. D.W. Stanley-Samuelson, D.R. Nelson (Eds.).
104. Van der Horst D.J., Van Doom J.M., Passier P.C.C.M., Vork M.M., Glatz J.F.C. Role of fatty acid-binding protein in lipid metabolism of insect flight muscle. Molecular and Cellular Biochemistry 1993, 123:145-152.
105. Van der Horst D.J., Van Marrewijk W.J.A., Vullings H.G.B., Diederen J.H.B. Metabolic neurohormones: Release, signal transduction and physiological responses of adipokinetic hormones in insects. European Journal of Entomology 1999, 96:299-308.
106. Van der Horst D.J., Van Marrewijk W.J.A., Diederen J.H.B. Adipokinetic hormones of insect: release, signal transduction, and responses. International Review of Cytology 2001, 211:179-240.
107. Van der Horst D.J., Van Hoof D., Van Marrewijk W.J.A., Rodenburg K.W. Alternative lipid mobilization: the insect shuttle system. Molecular and Cellular Biochemistry 2002, 239:113-119.
108. Van der Horst D.J., Ryan R.O. Lipid transport. Comprehensive Molecular Insect Science 2005, vol. 4:225-246. Elsevier, Amsterdam.
109. Van der Horst D.J., Roosendaal S.D., Rodenburg K.W. Circulatory lipid transport: lipoprotein assembly and function from an evolutionary perspective. Molecular and Cellular Biochemistry 2009, 326:105-119.
110. Van Heusden M.C., Van der Horst D.J., Voshol J., Beenakkrts A.M.Th. The recycling of protein components of the flight-specific lipophorin in Locusta migratoria. Insect Biochemistry 1987, 17:771-776.
111. Van Hoof D., Rodenburg K.W., Van der Horst D.J. Insect lipoprotein follows a transferrin-like recycling pathway that is mediated by the insect LDL receptor homologue. Journal of Cell Science 2002, 115:4001-4012.
112. Van Hoof D., Rodenburg K.W., Van der Horst D.J. Lipophorin receptor-mediated lipoprotein endocytosis in insect fat body cells. Journal of Lipid Research 2003, 44:1431-1440.
113. Van Hoof D., Rodenburg K.W., Van der Horst D.J. Receptor-mediated endocytosis and intracellular trafficking of lipoproteins and transferrin in insect cells. Insect Biochemistry and Molecular Biology 2005, 35:117-128.
114. Van Marrewijk W.J.A., Van den Broek A.Th.M., Van der Horst D.J., Beenakkers A.M.Th. Hypertrehalosaemic and hyperlipaemic response to adipokinetic hormone in fifth instar larval locusts, Locusta migratoria. Insect Biochemistry 1984, 14:151-157.
115. Van Marrewijk W.J.A., Van der Horst D.J. Signal transduction of adipokinetic hormone. Recent Advances in Arthropod Endocrinology 1998, 172-188. Cambridge University Press, Cambridge. G.M. Coast, S.G. Webster (Eds.).
116. Veelaert D., Schoofs L., De Loof A. Peptidergic control of the corpus cardiacum-corpora allata complex of locusts. International Reviews of Cytology 1998, 182:249-302.
117. i and cAMP. Molecular and Cellular Endocrinology 1995, 107:165-171.
118. q and not affected by cAMP. Insect Biochemistry and Molecular Biology 1998, 28:483-490.
119. Vroemen S.F., Van der Horst D.J., Van Marrewijk W.J.A. New insights into adipokinetic hormone signaling. Molecular and Cellular Endocrinology 1998, 141:7-12.
120. Vullings H.G.B., Diederen J.H.B., Veelaert D., Van der Horst D.J. Multifactorial control of the release of hormones from the locust retrocerebral complex. Microscopy Research and Technique 1999, 45:142-153.
121. Watt M.J., Steinberg G.R. Regulation and function of triacylglycerol lipases in cellular metabolism. Biochemical Journal 2008, 414:313-325.
122. Weers P.M.M., Van der Horst D.J., Van Marrewijk W.J.A., Van den Eijnden M., Van Doorn J.M., Beenakkers A.M.T. Biosynthesis and secretion of insect lipoprotein. Journal of Lipid Research 1992, 33:485-491.
123. Weers P.M.M., Van Marrewijk W.J.A., Beenakkers A.M.Th., Van der Horst D.J. Biosynthesis of locust lipophorin. Apolipophorins I and II originate from a common precursor. Journal of Biological Chemistry 1993, 268:4300-4303.
124. Weers P.M.M., Ryan R.O. Apolipophorin III: A lipid-triggered molecular switch. Insect Biochemistry and Molecular Biology 2003, 33:1249-1260.
125. Weers P.M.M., Ryan R.O. Apolipophorin III: Role model apolipophorin. Insect Biochemistry and Molecular Biology 2006, 36:231-240.
126. Weis-Fogh T. Fat combustion and metabolic rate of flying locusts (Schistocerca gregaria). Philosophical Transactions of the Royal Society (London) B 1952, 237:1-36.
127. L-proteins. Journal of Insect Physiology 1983, 29:349-354.
128. Wheeler C.H., Goldsworthy G.J. Qualitative and quantitative changes in Locusta haemolymph proteins and lipoproteins during ageing and adipokinetic hormone action. Journal of Insect Physiology 1983, 29:339-347.
129. Wheeler C.H., Van der Horst D.J., Beenakkers A.M.Th. Lipolytic activity in the flight muscles of Locusta migratoria measured with haemolymph lipoproteins as substrates. Insect Biochemistry 1984, 14:261-266.
130. Zechner R., Kienesberger P.C., Haemmerle G., Zimmermann R., Lass A. Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores. Journal of Lipid Research 2009, 50:3-21.