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Volumn 4, Issue 5, 2010, Pages 374-386

Dexamethasone treatment during the expansion phase maintains stemness of bone marrow mesenchymal stem cells

Author keywords

Dexamethasone; Differentiation; Expansion; Gene profiling; Mesenchymal stem cell; Multipotency; Senescence

Indexed keywords

CELL DEATH; CELL MEMBRANES; CELL PROLIFERATION; EXPANSION; STEM CELLS; TRANSCRIPTION;

EID: 77954276912     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.250     Document Type: Article
Times cited : (50)

References (54)
  • 1
    • 13544249606 scopus 로고    scopus 로고
    • Human mesenchymal stem cells modulate allogeneic immune cell responses
    • DOI 10.1182/blood-2004-04-1559
    • Aggarwal S, Pittenger MF. 2005; Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 105: 1815-1822. (Pubitemid 40223708)
    • (2005) Blood , vol.105 , Issue.4 , pp. 1815-1822
    • Aggarwal, S.1    Pittenger, M.F.2
  • 2
    • 0042622176 scopus 로고    scopus 로고
    • Effects of TGFβ1 and dexamethasone on the growth and chondrogenic differentiation of adipose derived stromal cells
    • Awad HA, Halvorsen YD, Gimble JM, et al. 2003; Effects of TGFβ1 and dexamethasone on the growth and chondrogenic differentiation of adipose derived stromal cells. Tissue Eng 9: 1301-1312.
    • (2003) Tissue Eng , vol.9 , pp. 1301-1312
    • Awad, H.A.1    Halvorsen, Y.D.2    Gimble, J.M.3
  • 5
    • 0028340485 scopus 로고
    • The mesengenic process
    • Caplan AI. 1994; The mesengenic process. Clin Plastic Surg 21(3): 429-435.
    • (1994) Clin Plastic Surg , vol.21 , Issue.3 , pp. 429-435
    • Caplan, A.I.1
  • 6
    • 33845393117 scopus 로고    scopus 로고
    • Osteogenic gene expression decreases in stromal cells of patients with osteonecrosis
    • Chang JK, Ho ML, Yeh CH, et al. 2006; Osteogenic gene expression decreases in stromal cells of patients with osteonecrosis. Clin Orthop 453: 286-292.
    • (2006) Clin Orthop , vol.453 , pp. 286-292
    • Chang, J.K.1    Ho, M.L.2    Yeh, C.H.3
  • 7
    • 0028009219 scopus 로고
    • Differentiation of human bone marrow osteogenic stromal cells in vitro: Induction of the osteoblast phenotype by dexamethasone
    • Cheng SL, Yang JW, Rifas L, et al. 1994; Differentiation of human bone marrow osteogenic stromal cells in vitro: induction of the osteoblast phenotype by dexamethasone. Endocrinology 134: 277-286.
    • (1994) Endocrinology , vol.134 , pp. 277-286
    • Cheng, S.L.1    Yang, J.W.2    Rifas, L.3
  • 10
    • 0141720695 scopus 로고    scopus 로고
    • Investigation of allogeneic mesenchymal stem cell-based alveolar bone formation: Preliminary findings
    • De Kok IJ, Peter SJ, Archambault M, et al. 2003; Investigation of allogeneic mesenchymal stem cell-based alveolar bone formation: preliminary findings. Clin Oral Implants Res 14: 481-489.
    • (2003) Clin Oral Implants Res , vol.14 , pp. 481-489
    • De Kok, I.J.1    Peter, S.J.2    Archambault, M.3
  • 11
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • Di Niccola M, Carlo-Stella C, Magni M, et al. 2002; Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 99: 3838-3843.
    • (2002) Blood , vol.99 , pp. 3838-3843
    • Di Niccola, M.1    Carlo-Stella, C.2    Magni, M.3
  • 12
    • 33646016858 scopus 로고    scopus 로고
    • Low oxygen tension inhibits osteogenic differentiation and enhances stemness of MIAMI cells
    • D'Ippolito G, Diabira S, Howard GA, et al. 2006; Low oxygen tension inhibits osteogenic differentiation and enhances stemness of MIAMI cells. Bone 39: 513-522.
    • (2006) Bone , vol.39 , pp. 513-522
    • D'Ippolito, G.1    Diabira, S.2    Howard, G.A.3
  • 13
    • 0036297840 scopus 로고    scopus 로고
    • Genome-wide screening by cDNA microarray of genes associated with matrix mineralization by human mesenchymal stem cells in vitro
    • Doi M, Nagano A, Nakamura Y. 2002; Genome-wide screening by cDNA microarray of genes associated with matrix mineralization by human mesenchymal stem cells in vitro. Biochem Biophys Res Comm 290: 381-390.
    • (2002) Biochem Biophys Res Comm , vol.290 , pp. 381-390
    • Doi, M.1    Nagano, A.2    Nakamura, Y.3
  • 14
  • 15
    • 33750621715 scopus 로고    scopus 로고
    • Effect of stratified culture compared to confluent culture in monolayer on proliferation and differentiation of human articular chondrocytes
    • DOI 10.1089/ten.2006.12.2397
    • Hendriks J, Riesle J, van Blitterswijk AC. 2006; The effect of stratified cultured compared to confluent culture in monolayer on proliferation and differentiation of human articular chondrocytes. Tissue Eng 12: 2397-2405. (Pubitemid 46141265)
    • (2006) Tissue Engineering , vol.12 , Issue.9 , pp. 2397-2405
    • Hendriks, J.1    Riesle, J.2    Van Blitterswijk, C.A.3
  • 16
    • 63049126562 scopus 로고    scopus 로고
    • Steroid regulation of proliferation and osteogenic differentiation of bone marrow stromal cells: A gender difference
    • Hong L, Sultana H, Paulius K, et al. 2009; Steroid regulation of proliferation and osteogenic differentiation of bone marrow stromal cells: a gender difference. J Steroid Biochem Mol Biol 114: 180-185.
    • (2009) J Steroid Biochem Mol Biol , vol.114 , pp. 180-185
    • Hong, L.1    Sultana, H.2    Paulius, K.3
  • 17
    • 0032976690 scopus 로고    scopus 로고
    • Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta
    • Horwitz EM, Prockop DJ, Fitzpatrick LA, et al. 1999; Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nat Med 5: 309-313.
    • (1999) Nat Med , vol.5 , pp. 309-313
    • Horwitz, E.M.1    Prockop, D.J.2    Fitzpatrick, L.A.3
  • 18
    • 0037173116 scopus 로고    scopus 로고
    • Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone
    • Horwitz EM, Gordon PL, Koo WK, et al. 2002; Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: implications for cell therapy of bone. Proc Natl Acad Sci USA 99: 8932-8937.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 8932-8937
    • Horwitz, E.M.1    Gordon, P.L.2    Koo, W.K.3
  • 19
    • 9444292842 scopus 로고    scopus 로고
    • Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction
    • Kawada H, Fujita J, Kinjo K, et al. 2004; Nonhematopoietic mesenchymal stem cells can be mobilized and differentiate into cardiomyocytes after myocardial infarction. Blood 104: 3581-3587.
    • (2004) Blood , vol.104 , pp. 3581-3587
    • Kawada, H.1    Fujita, J.2    Kinjo, K.3
  • 20
    • 0030885841 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 supports ex vivo expansion and maintenance of osteogenic precursors from human bone marrow
    • DOI 10.1210/en.138.10.4456
    • Martin I, Muraglia A, Campanile G, et al. 1997; Fibroblast growth factor-2 supports ex vivo expansion andmainterance of osteogenic precursors from human bone marrow. Endocrinology 138: 4456-4462. (Pubitemid 27408494)
    • (1997) Endocrinology , vol.138 , Issue.10 , pp. 4456-4462
    • Martin, I.1    Muraglia, A.2    Campanile, G.3    Cancedda, R.4    Quarto, R.5
  • 21
    • 0033977382 scopus 로고    scopus 로고
    • Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy
    • Koc ON, Gerson SL, Cooper BW, et al. 2000; Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapy. J Clin Oncol 18: 307-316.
    • (2000) J Clin Oncol , vol.18 , pp. 307-316
    • Koc, O.N.1    Gerson, S.L.2    Cooper, B.W.3
  • 22
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide
    • DOI 10.1182/blood-2002-07-2104
    • Krampera M, Glennie S, Dyson J, et al. 2003; Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 101: 3722-3729. (Pubitemid 36857965)
    • (2003) Blood , vol.101 , Issue.9 , pp. 3722-3729
    • Krampera, M.1    Glennie, S.2    Dyson, J.3    Scott, D.4    Laylor, R.5    Simpson, E.6    Dazzi, F.7
  • 23
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • DOI 10.1016/S0140-6736(04)16104-7, PII S0140673604161047
    • Le Blanc K, Rasmusson I, Sundberg B, et al. 2004; Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 363: 1439-1441. (Pubitemid 38586721)
    • (2004) Lancet , vol.363 , Issue.9419 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3    Gotherstrom, C.4    Hassan, M.5    Uzunel, M.6    Ringden, O.7
  • 24
    • 10644283018 scopus 로고    scopus 로고
    • In vitro hepatic differentiation of human mesenchymal stem cells
    • Lee KD, Kuo TK, Whang-Peng J, et al. 2004; In vitro hepatic differentiation of human mesenchymal stem cells. Hepatology 40: 1275-1284.
    • (2004) Hepatology , vol.40 , pp. 1275-1284
    • Lee, K.D.1    Kuo, T.K.2    Whang-Peng, J.3
  • 25
    • 0033678140 scopus 로고    scopus 로고
    • Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep
    • Liechty KW, MacKenzie TC, Shaaban AF, et al. 2000; Human mesenchymal stem cells engraft and demonstrate site-specific differentiation after in utero transplantation in sheep. Nat Med 6: 1282-1286.
    • (2000) Nat Med , vol.6 , pp. 1282-1286
    • Liechty, K.W.1    MacKenzie, T.C.2    Shaaban, A.F.3
  • 26
    • 0036892070 scopus 로고    scopus 로고
    • Bone tissue-engineered implants using human bone marrow stromal cells: Effect of culture conditions and donor age
    • Mendes SC, Tibbe JM, Veenhof K, et al. 2002; Bone tissue-engineered implants using human bone marrow stromal cells: effect of culture conditions and donor age. Tissue Eng 8: 911-920.
    • (2002) Tissue Eng , vol.8 , pp. 911-920
    • Mendes, S.C.1    Tibbe, J.M.2    Veenhof, K.3
  • 27
    • 0034056758 scopus 로고    scopus 로고
    • Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model
    • Muraglia A, Cancedda R, Quarto R. 2000; Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model. J Cell Sci 113: 1161-1166. (Pubitemid 30229533)
    • (2000) Journal of Cell Science , vol.113 , Issue.7 , pp. 1161-1166
    • Muraglia, A.1    Cancedda, R.2    Quarto, R.3
  • 28
    • 0034130914 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocoticoid action: What is important?
    • Newton R. 2000; Molecular mechanisms of glucocoticoid action: what is important? Thorax 55: 603-613.
    • (2000) Thorax , vol.55 , pp. 603-613
    • Newton, R.1
  • 29
    • 0029036412 scopus 로고
    • Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis
    • Petit PX, Lecoeur H, Zorn E, et al. 1995; Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis. J Cell Biol 130: 157-167.
    • (1995) J Cell Biol , vol.130 , pp. 157-167
    • Petit, P.X.1    Lecoeur, H.2    Zorn, E.3
  • 30
    • 0033485750 scopus 로고    scopus 로고
    • Donor variation in the growth properties and osteogenic potential of human marrow stromal cells
    • DOI 10.1002/(SICI)1097-4644(19991201)75:3<424::AID-JCB8>3.0.CO;2-8
    • Phinney DG, Kopen G, Righter W, et al. 1999; Donor variation in the growth properties and osteogenic potential of human marrow stromal cells. J Cell Biochem 75: 424-436. (Pubitemid 29521651)
    • (1999) Journal of Cellular Biochemistry , vol.75 , Issue.3 , pp. 424-436
    • Phinney, D.G.1    Kopen, G.2    Righter, W.3    Webster, S.4    Tremain, N.5    Prockop, D.J.6
  • 32
    • 0008970253 scopus 로고    scopus 로고
    • Mesenchymal stem cells
    • Koller MR, Palsson BO, Master JRW (eds). Kluwer Academic: Amsterdam, 2001 Chapter 9
    • Pittenger MF, Mbalaviele G, Black M, et al. 2001; Mesenchymal stem cells. In Human Cell Culture, Koller MR, Palsson BO, Master JRW (eds). Kluwer Academic: Amsterdam, 2001 Chapter 9.
    • (2001) Human Cell Culture
    • Pittenger, M.F.1    Mbalaviele, G.2    Black, M.3
  • 33
    • 3142663241 scopus 로고    scopus 로고
    • Mesenchymal stem cells and their potential as cardiac therapeutics
    • DOI 10.1161/01.RES.0000135902.99383.6f
    • Pittenger MF, Martin BJ. 2004; Mesenchymal stem cells and their potential as cardiac therapeutics. Circ Res 95: 9-20. (Pubitemid 38931831)
    • (2004) Circulation Research , vol.95 , Issue.1 , pp. 9-20
    • Pittenger, M.F.1    Martin, B.J.2
  • 34
    • 0030889354 scopus 로고    scopus 로고
    • Marrow stromal cells as stem cells for nonhematopoietic tissues
    • DOI 10.1126/science.276.5309.71
    • Prockop DJ. 1997; Marrow stromal cells as stem cells of nonhematopoietic tissue. Science 276: 71-74. (Pubitemid 27161245)
    • (1997) Science , vol.276 , Issue.5309 , pp. 71-74
    • Prockop, D.J.1
  • 36
    • 77954274168 scopus 로고    scopus 로고
    • Cardiac differentiated adult human bone marrow stem cells express sarcomeric and structural proteins of cardiomyocytes
    • Shim WSN, Tan GMY, Wong P. 2005; Cardiac differentiated adult human bone marrow stem cells express sarcomeric and structural proteins of cardiomyocytes. Microsc Microanal 11(suppl 2): 912-913.
    • (2005) Microsc Microanal , vol.11 , Issue.SUPPL. 2 , pp. 912-913
    • Shim, W.S.N.1    Tan, G.M.Y.2    Wong, P.3
  • 37
    • 34447283203 scopus 로고    scopus 로고
    • Donor variation and loss of multipotency during in vitro expansion of human mesenchymal stem cells for bone tissue engineering
    • DOI 10.1002/jor.20402
    • Siddappa R, Licht R, van Blitterswijk CA, et al. 2007; Donor variation and loss of multipotency of human mesenchymal stem cells during in vitro expansion of human mesenchymal stem cells for bone tissue engineering. J Orthop Res 25: 1029-1041. (Pubitemid 47233079)
    • (2007) Journal of Orthopaedic Research , vol.25 , Issue.8 , pp. 1029-1041
    • Siddappa, R.1    Licht, R.2    Van Blitterswijk, C.3    De Boer, J.4
  • 38
    • 24644519036 scopus 로고    scopus 로고
    • Harnessing the stem cell for the treatment of tendon injuries: Heralding a new dawn?
    • Smith RK, Webbon PM. 2005; Harnessing the stem cell for the treatment of tendon injuries: heralding a new dawn? Br J Sports Med 39: 582-584.
    • (2005) Br J Sports Med , vol.39 , pp. 582-584
    • Smith, R.K.1    Webbon, P.M.2
  • 39
    • 0347627149 scopus 로고    scopus 로고
    • Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells
    • Stenderup K, Justesen J, Clausen C, et al. 2003; Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells. Bone 33: 919-920.
    • (2003) Bone , vol.33 , pp. 919-920
    • Stenderup, K.1    Justesen, J.2    Clausen, C.3
  • 40
    • 33749060495 scopus 로고    scopus 로고
    • Identification and functional analysis of candidate genes regulating mesenchymal stem cell self-renewal and multipotency
    • Song L, Webb NE, Song YJ, et al. 2006; Identification and functional analysis of candidate genes regulating mesenchymal stem cell self-renewal and multipotency. Stem Cells 24: 1707-1708.
    • (2006) Stem Cells , vol.24 , pp. 1707-1708
    • Song, L.1    Webb, N.E.2    Song, Y.J.3
  • 41
    • 59449100396 scopus 로고    scopus 로고
    • Dexamethasone inhibition of confluence-induced apoptosis in human mesenchymal stem cells
    • Song IH, Caplan AI, Dennis JE. 2009; Dexamethasone inhibition of confluence-induced apoptosis in human mesenchymal stem cells. J Orthop Res 27: 216-221.
    • (2009) J Orthop Res , vol.27 , pp. 216-221
    • Song, I.H.1    Caplan, A.I.2    Dennis, J.E.3
  • 42
    • 33646039757 scopus 로고    scopus 로고
    • Glucose-induced replicative senescence in mesenchymal stem cells
    • Stolzing A, Coleman N, Scutt A. 2006; Glucose-induced replicative senescence in mesenchymal stem cells. Rejuvenation Res 9: 31-35.
    • (2006) Rejuvenation Res , vol.9 , pp. 31-35
    • Stolzing, A.1    Coleman, N.2    Scutt, A.3
  • 43
    • 10044230580 scopus 로고    scopus 로고
    • Autologous serum for isolation and expansion of human mesenchymal stem cells for clinical use
    • Stute N, Holtz K, Bubenheim M, et al. 2004; Autologous serum for isolation and expansion of human mesenchymal stem cells for clinical use. Exp Hematol 32: 1212-1225.
    • (2004) Exp Hematol , vol.32 , pp. 1212-1225
    • Stute, N.1    Holtz, K.2    Bubenheim, M.3
  • 44
    • 32344451060 scopus 로고    scopus 로고
    • Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells
    • Timper K, Seboek D, Eberhardt M, et al. 2006; Human adipose tissue-derived mesenchymal stem cells differentiate into insulin, somatostatin, and glucagon expressing cells. Biochem Biophys Res Commun 341: 1135-1140.
    • (2006) Biochem Biophys Res Commun , vol.341 , pp. 1135-1140
    • Timper, K.1    Seboek, D.2    Eberhardt, M.3
  • 45
    • 0036142213 scopus 로고    scopus 로고
    • Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart
    • Toma C, Pittenger MF, Cahill KS, et al. 2002; Human mesenchymal stem cells differentiate to a cardiomyocyte phenotype in the adult murine heart. Circulation 105: 93-98.
    • (2002) Circulation , vol.105 , pp. 93-98
    • Toma, C.1    Pittenger, M.F.2    Cahill, K.S.3
  • 46
    • 0028236527 scopus 로고
    • Mesenchymal cell-based repair of large, full-thickness defects of articular cartilage
    • Wakitani S, Goto T, Pineda SJ, et al. 1994; Mesenchymal cell-based repair of large, full-thickness defects of articular cartilage. J Bone Joint Surg Am 76: 579-592.
    • (1994) J Bone Joint Surg Am , vol.76 , pp. 579-592
    • Wakitani, S.1    Goto, T.2    Pineda, S.J.3
  • 47
    • 0028788268 scopus 로고
    • Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine
    • Wakitani S, Saito T, Caplan AI. 1995; Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine. Muscle Nerve 18: 1417-1426.
    • (1995) Muscle Nerve , vol.18 , pp. 1417-1426
    • Wakitani, S.1    Saito, T.2    Caplan, A.I.3
  • 48
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat and human bone marrow stromal cells differentiate into neurons
    • Woodbury D, Schwarz EJ, Prockop DJ, et al. 2000; Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 61: 364-370.
    • (2000) J Neurosci Res , vol.61 , pp. 364-370
    • Woodbury, D.1    Schwarz, E.J.2    Prockop, D.J.3
  • 49
    • 0035144210 scopus 로고    scopus 로고
    • High concentrations of dexamethasone suppress the proliferation but not the differentiation or further maturation of human osteoblast precursors in vitro: Relevance to glucocorticoid-induced osteoporosis
    • Walsh S, Jordan GR, Jefferiss C, et al. 2001; High concentrations of dexamethasone suppress the proliferation but not the differentiation or further maturation of human osteoblast precursors in vitro: relevance to glucocorticoid-induced osteoporosis. Rheumatology 40: 74-83.
    • (2001) Rheumatology , vol.40 , pp. 74-83
    • Walsh, S.1    Jordan, G.R.2    Jefferiss, C.3
  • 50
    • 0033969351 scopus 로고    scopus 로고
    • The Nicolas Andry Award. The pathogenesis and prevention of steroid-induced osteonecrosis
    • Wang GJ, Cui Q, Balian G. 2000; The Nicolas Andry Award. The pathogenesis and prevention of steroid-induced osteonecrosis. Clin Orthop 370: 295-310.
    • (2000) Clin Orthop , vol.370 , pp. 295-310
    • Wang, G.J.1    Cui, Q.2    Balian, G.3
  • 51
    • 0030726176 scopus 로고    scopus 로고
    • Dexamethasone inhibits lung epithelial cell apoptosis induced by IFN-γ and Fas
    • Wen LP, Madani K, Fahrni JA, et al. 1997; Dexamethasone inhibits lung epithelial cell apoptosis induced by IFN-γ and Fas. Am J Physiol Lung Cell Mol Physiol 273: L921-929.
    • (1997) Am J Physiol Lung Cell Mol Physiol , vol.273
    • Wen, L.P.1    Madani, K.2    Fahrni, J.A.3
  • 52
    • 0032125757 scopus 로고    scopus 로고
    • Interleukin-6-induced inhibition of multiple myeloma cell apoptosis: Support for the hypothesis that protection is mediated via inhibition of the JNK/SAPK pathway
    • Xu FH, Sharma S, Gardner A, et al. 1998; Interleukin-6-induced inhibition of multiple myeloma cell apoptosis: support for the hypothesis that protection is mediated via inhibition of the JNK/SAPK pathway. Blood 92: 241-251.
    • (1998) Blood , vol.92 , pp. 241-251
    • Xu, F.H.1    Sharma, S.2    Gardner, A.3
  • 53
    • 33845234231 scopus 로고    scopus 로고
    • Stem cells with potential to generate insulin-producing cells in man
    • Zulewski H. 2006; Stem cells with potential to generate insulin-producing cells in man. Swiss Med Wkly 136: 647-654.
    • (2006) Swiss Med Wkly , vol.136 , pp. 647-654
    • Zulewski, H.1
  • 54
    • 18744373595 scopus 로고    scopus 로고
    • Human adipose tissue is a source of multipotent stem cells
    • Zuk PA, Zhu M, Ashjian P, et al. 2002; Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 13: 4279-4295.
    • (2002) Mol Biol Cell , vol.13 , pp. 4279-4295
    • Zuk, P.A.1    Zhu, M.2    Ashjian, P.3


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