메뉴 건너뛰기




Volumn 15, Issue 6, 2010, Pages 3932-3957

Synthesis, characterization and biological studies of some novel thieno[2,3-d]pyrimidines

Author keywords

Antibacterial activity; Cytotoxic activity; Thienopyridines; Triazolothienopyrimidines

Indexed keywords

PYRIMIDINE DERIVATIVE; THIENOPYRIMIDINE;

EID: 77954255036     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules15063932     Document Type: Article
Times cited : (42)

References (23)
  • 1
    • 0034913996 scopus 로고    scopus 로고
    • Pyrazolopyrimidines: Synthesie, effect on histamine release from rat peritoneal mast cells and cytotoxic activity
    • Quintela, J.; Peinador, C.; Moreira, M.; Alfonso, A.; Botana, L.; Riguera, R. Pyrazolopyrimidines: synthesie, effect on histamine release from rat peritoneal mast cells and cytotoxic activity. Eur. J. Med. Chem. 2001, 36, 321-332.
    • (2001) Eur. J. Med. Chem. , vol.36 , pp. 321-332
    • Quintela, J.1    Peinador, C.2    Moreira, M.3    Alfonso, A.4    Botana, L.5    Riguera, R.6
  • 3
    • 34248196393 scopus 로고    scopus 로고
    • Synthesis of some new bioactive 3-amino-2-mercabto-5, 6, 7, 8-tetrahydro [1] benzothieno [2, 3-d] pyrimidin-4-one derivatives
    • Ashalatha, B. V.; Narayana, B.; Vijaya raj, K. K.; Kumari, S. Synthesis of some new bioactive 3-amino-2-mercabto-5, 6, 7, 8-tetrahydro [1] benzothieno [2, 3-d] pyrimidin-4-one derivatives. Eur. J. Med. Chem. 2007, 42, 719-728.
    • (2007) Eur. J. Med. Chem. , vol.42 , pp. 719-728
    • Ashalatha, B.V.1    Narayana, B.2    Raj, V.K.K.3    Kumari, S.4
  • 6
    • 76049086339 scopus 로고
    • Heterocycles from CH-acidic nitriles. VII 2 aminothiophene from a-oxo mercaptans and methylene-active nitriles
    • Gewald, K. Heterocycles from CH-acidic nitriles. VII 2 aminothiophene from a-oxo mercaptans and methylene-active nitriles. Chem. Ber. 1965, 98, 3571-3577.
    • (1965) Chem. Ber. , vol.98 , pp. 3571-3577
    • Gewald, K.1
  • 7
    • 34249992286 scopus 로고    scopus 로고
    • Synthesis of 2-mercapto-3-substituted-5, 6-dimethylthieno[2, 3-d]pyrimidin-4 (3H)-ones as new analgesic, anti-inflammatory agents
    • Alagarsamy, V.; Vijayakumar, S.; Solomon, V. R. Synthesis of 2-mercapto-3-substituted-5, 6-dimethylthieno[2, 3-d]pyrimidin-4 (3H)-ones as new analgesic, anti-inflammatory agents. Biomed. Phamacol. 2007, 61, 285-291.
    • (2007) Biomed. Phamacol , vol.61 , pp. 285-291
    • Alagarsamy, V.1    Vijayakumar, S.2    Solomon, V.R.3
  • 8
    • 33845293428 scopus 로고    scopus 로고
    • Synthesis and anti microbial evaluation of some new thienopyrimidine derivatives
    • Bhutyan, M.; Rahman, M.; Abdurrahim, K.; Hossain, M.; Abunaser, M. Synthesis and anti microbial evaluation of some new thienopyrimidine derivatives. Acta Pharm. 2006, 56, 411-450.
    • (2006) Acta Pharm. , vol.56 , pp. 411-450
    • Bhutyan, M.1    Rahman, M.2    Abdurrahim, K.3    Hossain, M.4    Abunaser, M.5
  • 9
    • 0029011389 scopus 로고
    • Synthesis, antimicrobial and antiviral evaluation of certain thienopyrimidine derivatives
    • El-Sherbeny, M. A.; El-Ashmawy, M. B.; El-Subbagh, H. I.; El-Emam, A. A.; Synthesis, antimicrobial and antiviral evaluation of certain thienopyrimidine derivatives. Eur. J. Med. Chem. 1995, 30, 445-449.
    • (1995) Eur. J. Med. Chem. , vol.30 , pp. 445-449
    • El-Sherbeny, M.A.1    El-Ashmawy, M.B.2    El-Subbagh, H.I.3    El-Emam, A.A.4
  • 10
    • 33750517493 scopus 로고    scopus 로고
    • Synthesis, analgesic, anti-inflammatory, ucerogenic index and antibacterial activities of novel 2-methylthio-3-substituted-5, 6, 7, 8-tetrahydrobenzo (b) thieno[2, 3-d]pyrimidin-4-(3H)-ones
    • Alagarsamy, V.; Meena, S.; Ramseshu, K. V.; Solomon, V. R.; Thirumuruganb, K.; Dhanabala, K.; Murugan, M. Synthesis, analgesic, anti-inflammatory, ucerogenic index and antibacterial activities of novel 2-methylthio-3-substituted-5, 6, 7, 8-tetrahydrobenzo (b) thieno[2, 3-d]pyrimidin-4-(3H)-ones. Eur. J. Med. Chem. 2006, 41, 1293-1300.
    • (2006) Eur. J. Med. Chem. , vol.41 , pp. 1293-1300
    • Alagarsamy, V.1    Meena, S.2    Ramseshu, K.V.3    Solomon, V.R.4    Thirumuruganb, K.5    Dhanabala, K.6    Murugan, M.7
  • 11
    • 67650083498 scopus 로고    scopus 로고
    • Synthesis, antitumor evaluation, molecular modeling and quantitative structure-activity relationship (QSAR) of some novel arylazopyrazolodiazine and triazine analogs
    • El-Shafei, A.; Fadda, A. A.; Khalil, A. M.; Ameen. T. A. E.; Badria, F. A. Synthesis, antitumor evaluation, molecular modeling and quantitative structure-activity relationship (QSAR) of some novel arylazopyrazolodiazine and triazine analogs. Bioorg. Med. Chem. 2009, 17, 5096-5105.
    • (2009) Bioorg. Med. Chem. , vol.17 , pp. 5096-5105
    • El-Shafei, A.1    Fadda, A.A.2    Khalil, A.M.3    Ameen, T.A.E.4    Badria, F.A.5
  • 12
    • 4043151682 scopus 로고    scopus 로고
    • Synthesis of Some new substituted Thieno[2, 3-d]pyrimidines and related heterocyclic systems
    • El-Baih, F. E. M; Al-Taisan, K. M.; Al-Hazimi, H. M. Synthesis of Some new substituted Thieno[2, 3-d]pyrimidines and related heterocyclic systems. J. Stat. Comput. Simul. 2000, 4, 281-290.
    • (2000) J. Stat. Comput. Simul , vol.4 , pp. 281-290
    • El-Baih, F.E.M.1    Al-Taisan, K.M.2    Al-Hazimi, H.M.3
  • 13
    • 33747448654 scopus 로고    scopus 로고
    • Synthesis of some thienopyrimidine derivatives
    • El-Baih, F. E. M.; Al-Blowy, H. A. S.; AL-Hazimi, H. M. Synthesis of Some Thienopyrimidine Derivatives. Molecules 2006, 11, 498-513.
    • (2006) Molecules , vol.11 , pp. 498-513
    • El-Baih, F.E.M.1    Al-Blowy, H.A.S.2    Al-Hazimi, H.M.3
  • 14
    • 84860875380 scopus 로고
    • 2-Amin-thiophene aus methylenakteven Nitrilen, Carbonylverbindungen und Schwefel
    • Gewald, K.; Schinke, E.; Bottcher. H. 2-Amin-thiophene aus methylenakteven Nitrilen, Carbonylverbindungen und Schwefel. Chem. Ber. 1966, 99, 94-100.
    • (1966) Chem. Ber. , vol.99 , pp. 94-100
    • Gewald, K.1    Schinke, E.2    Bottcher, H.3
  • 15
    • 0000629211 scopus 로고
    • Folate Antagonists. 6. Synthesis and antimalarial effects of fused 2, 4-diaminothieno[2, 3-d] pyrimidine (1-3)
    • Elslager, E.; Jacob, P.; Werbel, L. Folate Antagonists. 6. Synthesis and Antimalarial Effects of Fused 2, 4-Diaminothieno[2, 3-d] pyrimidine (1-3). J. Heterocycl. Chem. 1972, 11, 775-782.
    • (1972) J. Heterocycl. Chem. , vol.11 , pp. 775-782
    • Elslager, E.1    Jacob, P.2    Werbel, L.3
  • 18
    • 0025341331 scopus 로고
    • New colorimetric cytotoxicity assay for anti-cancer drug screening
    • Skehan P. New colorimetric cytotoxicity assay for anti-cancer drug screening. J. Natl. Cancer Inst. 1990, 82, 1107-1112.
    • (1990) J. Natl. Cancer Inst. , vol.82 , pp. 1107-1112
    • Skehan, P.1
  • 22
    • 0032761856 scopus 로고    scopus 로고
    • Fusions of pyrido[4', 3':4, 5]thieno[2, 3-d] pyrimidines with N-heterocyclic moieties
    • Ahmed, E. Kh.; Sensfuss, U.; Habicher, W. D. Fusions of Pyrido[4', 3':4, 5]thieno[2, 3-d] pyrimidines with N-Heterocyclic Moieties. J. Heterocycl. Chem. 1999, 36, 1119-1122.
    • (1999) J. Heterocycl. Chem. , vol.36 , pp. 1119-1122
    • Ahmed, E.K.1    Sensfuss, U.2    Habicher, W.D.3
  • 23
    • 3342944253 scopus 로고    scopus 로고
    • A simple synthesis of some new thienopyridine and thienopyrimidine derivatives
    • El-Saghier, A. M. A Simple Synthesis of Some New Thienopyridine and Thienopyrimidine Derivatives. Molecules 2002, 7, 756-766.
    • (2002) Molecules , vol.7 , pp. 756-766
    • El-Saghier, A.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.