Views on personalized medicine: Do the attitudes of African American and white prescription drug consumers differ?

Public Health Genomics

Volumn 13, Issue 5, 2010, Pages 276-283

  De Marco, M ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

African Americans; Focus groups; Genetic testing; Personalized medicine; Race based prescribing

Indexed keywords

ADULT; AFRICAN AMERICAN; AGED; ARTICLE; AUDIO RECORDING; CLINICAL ARTICLE; CONSUMER ATTITUDE; CONTROLLED STUDY; DRUG COMPATIBILITY; DRUG SCREENING; EUROPEAN AMERICAN; FEMALE; GENETIC SCREENING; HUMAN; INFORMATION PROCESSING; MALE; PHARMACOGENOMICS; PRESCRIPTION; PRIORITY JOURNAL; RACE DIFFERENCE; ATTITUDE; BLACK PERSON; CAUCASIAN; PERSONALIZED MEDICINE; PSYCHOLOGY;

AFRICAN CONTINENTAL ANCESTRY GROUP; ATTITUDE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FOCUS GROUPS; GENETIC TESTING; HUMANS; INDIVIDUALIZED MEDICINE; PRESCRIPTION DRUGS; PRECISION MEDICINE;

PRESCRIPTION DRUG;

EID: 77954243662     PISSN: 16624246     EISSN: None     Source Type: Journal    
DOI: 10.1159/000242199     Document Type: Article

References (19)

1. Smart A, Martin P, Parker M: Tailored medicine: whom will it fit? The ethics of patient and disease stratification. Bioethics 2004; 18: 322-342.
2. Secretary's Advisory Committee on Genetics, Health, & Society. Realizing the Potential of Pharmacogenomics: Opportunities and Challenges: 2008. Available at http://www4. od.nih.gov/oba/sacghs/reports/SACGHS- PGx-report.pdf, accessed June 30, 2008.
3. Almarsdottir A, Bjornsdottir I, Traulsen J: A lay prescription for tailor-made drugs - focus group reflections on pharmacogenetics. Health Policy 2005; 71: 233-241.
4. Catz DS, Green NS, Tobin JN, Lloyd-Puryear MA, Kyler P, Umemoto A, Cernoch J, Brown R, Wolman F: Attitudes about genetics in underserved, culturally diverse populations. Community Genet 2005; 8: 161-172.
5. Condit C, Parrot R, Bates B, Bevan J, Achter P: Exploration of the impact of messages about genes and race on lay attitudes. Clin Genet 2004; 66: 402-408.
6. Bevan JL, Lynch JA, Dubriwny TN, Harris TM, Achter PJ, Reeder AL, Condit CM: Informed lay preferences for delivery of racially varied pharmacogenomics. Genet Med 2003; 5: 393-399.
7. Corbie-Smith G: The continuing legacy of the Tuskegee Syphilis Study: considerations for clinical investigation. Am J Med Sci 1999; 317: 5-8.
8. Gamble V: Under the shadow of Tuskegee: African Americans and health care. Am J Public Health 1997; 87: 1773-1778.
9. Thomas SB, Quinn SC: The Tuskegee Syphilis Study, 1932 to 1972: Implications for HIV education and AIDS risk education programs in the black community. Am J Public Health 1991; 81: 1498-1505.
10. Israel BA, Schulz AJ, Parker EA, Becker AB, Allen A, Guzman JR: Critical issues in developing and following community-based participatory research principles; in Minkler M, Wallerstein N (eds): Community-Based Participatory Research for Health. San Francisco, Jossey-Bass, 2003, pp 56-73.
11. Viswanathan M, Ammerman A, Eng E, Gartlehner G, Lohr KN, Griffith D, Rhodes, S, Samuel-Hodge C, Maty S, Lux L, Webb L, Sutton S, Swinson T, Jackman A, Whitener L: Community-Based Participatory Research: Assessing the Evidence. Report/ Technology Assessment No.99 (Prepared by RTI-University of North Carolina Evidencebased Practice Center under Contract No. 290-02-0016). AHRQ Publication 04-E022- 2. Rockville, MD: Agency for Healthcare Research and Quality. July 2004. Available at http://www.ahrq.gov/downloads/pub/evidence/ pdf/cbpr/cbpr.pdf.
12. Berg B: Qualitative Research Methods for the Social Sciences, ed 5. Boston, Pearson, 2004.
13. Taylor A, Cohn J, Worcel M, Franciosa J: The African-American Heart Failure Trial: background, rationale, and significance. J Natl Med Assoc 2002; 94: 762-769.
14. Liggett SB, Cresci S, Kelly RJ, Syed FM, Matkovich SJ, Hahn HS, Diwan A, Martini JS, Sparks L, Parekh RR, Spertus JA, Koch WJ, Kardia SL, Dorn GW 2nd: A GRK5 polymorphism that inhibitsβ-adrenergic receptor signaling is protective in heart failure. Nat Med 2008; 14: 510-517.
15. He W, Neil S, Kulkarni H, Wright E, Agan BK, Marconi VC, Dolan MJ, Weiss RA, Ahuja SK: Duffy antigen receptor for chemokines mediates trans-infection of HIV-1 from red blood cells to target cells and affects HIV-AIDS susceptibility. Cell Host Microbe 2008; 4: 52-62.
16. Rotimi C, Leppert M, Matsuda I, Zeng C, Zhang H, Adebamowo C, Ajayi I, Aniagwu T, Dixon M, Fukushima Y, Macer D, Marshall P, Nkwodimmah C, Peiffer A, Royal C, Suda E, Zhao H, Wang VO, McEwen J; International HapMap Consortium: Community engagement and informed consent in the International HapMap project. Community Genet 2007; 10: 186-198.
17. Bottinger E: Foundations, promises, and uncertainties of personalized medicine. Mt Sinai J Med 2007; 74: 15-21.
18. Lee C, Morton C: Structural genomic variation and personalized medicine. N Engl J Med 2008; 358: 740-741.
19. Washington H: Medical Apartheid: The Dark History of Medical Experimentation on Black Americans from Colonial Times to the Present. New York, Doubleday, 2006.