Amplification of GNAS may be an independent, qualitative, and reproducible biomarker to predict progression-free survival in epithelial ovarian cancer

Gynecologic Oncology

Volumn 118, Issue 2, 2010, Pages 160-166

  Tominaga, Ei Ichiro ^a   Tsuda, Hiroshi ^a   Arao, Tokuzo ^b   Nishimura, Sadako ^c   Takano, Masashi ^d   Kataoka, Fumio ^a   Nomura, Hiroyuki ^a   Hirasawa, Akira ^a   Aoki, Daisuke ^a   Nishio, Kazuto ^b  

^a KEIO UNIVERSITY   (Japan)

^b KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c OSAKA CITY GENERAL HOSPITAL   (Japan)

^d NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

Author keywords

Amplification; Biomarker; Carboplatin; Ovarian cancer; Paclitexal; Prognosis

Indexed keywords

BIOLOGICAL MARKER; CARBOPLATIN; MESSENGER RNA; PACLITAXEL; PROTEIN G ALPHA S 1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER SURGERY; CHROMOSOME 20; CHROMOSOME 8; CLINICAL ARTICLE; COPY NUMBER VARIATION; DISEASE COURSE; EPITHELIAL OVARIAN CANCER; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION; GENE IDENTIFICATION; GENE LOCUS; HUMAN; HUMAN TISSUE; LAPAROTOMY; LASER MICRODISSECTION; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; OVARY CANCER; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROGRESSION FREE SURVIVAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARBOPLATIN; CHEMOTHERAPY, ADJUVANT; DISEASE-FREE SURVIVAL; EPITHELIAL CELLS; FEMALE; GENE AMPLIFICATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OVARIAN NEOPLASMS; PACLITAXEL; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; TUMOR MARKERS, BIOLOGICAL;

EID: 77954243209     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2010.03.010     Document Type: Article

References (27)

1. Y. Ben David, A. Chetrit, G. Hirsh-Yechezkel, E. Friedman, B.D. Beck, and U. Beller Effect of BRCA mutations on the length of survival in epithelial ovarian tumors J Clin Oncol 20 2 2002 463 466
2. Y.T. Tai, S. Lee, E. Niloff, C. Weisman, T. Strobel, and S.A. Cannistra BAX protein expression and clinical outcome in epithelial ovarian cancer J Clin Oncol 16 8 1998 2583 2590
3. T. Kusume, H. Tsuda, M. Kawabata, T. Inoue, N. Umesaki, and T. Suzuki The p16-cyclin D1/CDK4-pRb pathway and clinical outcome in epithelial ovarian cancer Clin Cancer Res 5 12 1999 4152 4157
4. D. Spentzos, D.A. Levine, M.F. Ramoni, M. Joseph, X. Gu, and J. Boyd Gene expression signature with independent prognostic significance in epithelial ovarian cancer J Clin Oncol 22 23 2004 4700 4710
5. H. Tsuda, Y.M. Ito, Y. Ohashi, K.K. Wong, Y. Hashiguchi, and W.R. Welch Identification of overexpression and amplification of ABCF2 in clear cell ovarian adenocarcinomas by cDNA microarray analyses Clin Cancer Res 11 19 Pt 1 2005 6880 6888
6. D. Spentzos, D.A. Levine, S. Kolia, H. Otu, J. Boyd, and T.A. Libermann Unique gene expression profile based on pathologic response in epithelial ovarian cancer J Clin Oncol 23 31 2005 7911 7918
7. M.J. Birrer, M.E. Johnson, K. Hao, K.K. Wong, D.C. Park, and A. Bell Whole genome oligonucleotide-based array comparative genomic hybridization analysis identified fibroblast growth factor 1 as a prognostic marker for advanced-stage serous ovarian adenocarcinomas J Clin Oncol 25 16 2007 2281 2287
8. M. Takano, Y. Kikuchi, N. Yaegashi, K. Kuzuya, M. Ueki, and H. Tsuda Clear cell carcinoma of the ovary: a retrospective multicentre experience of 254 patients with complete surgical staging Br J Cancer 94 10 2006 1369 1374
9. V. Hess, R. A'Hern, N. Nasiri, D.M. King, P.R. Blake, and D.P. Barton Mucinous epithelial ovarian cancer: a separate entity requiring specific treatment J Clin Oncol 22 6 2004 1040 1044 (Pubitemid 41095036)
10. N. Arnold, L. Hagele, L. Walz, W. Schempp, J. Pfisterer, and T. Bauknecht Overrepresentation of 3q and 8q material and loss of 18q material are recurrent findings in advanced human ovarian cancer Genes Chromosom Cancer 16 1 1996 46 54
11. D. Mayr, V. Kanitz, B. Anderegg, B. Luthardt, J. Engel, and U. Lohrs Analysis of gene amplification and prognostic markers in ovarian cancer using comparative genomic hybridization for microarrays and immunohistochemical analysis for tissue microarrays Am J Clin Pathol 126 1 2006 101 109
12. O. Israeli, W.H. Gotlieb, E. Friedman, J. Korach, B. Goldman, and A. Zeltser Genomic analyses of primary and metastatic serous epithelial ovarian cancer Cancer Genet Cytogenet 154 1 2004 16 21
13. A. Schipf, D. Mayr, T. Kirchner, and J. Diebold Molecular genetic aberrations of ovarian and uterine carcinosarcomas-a CGH and FISH study Virchows Arch 452 3 2008 259 268
14. Kaneda H, Arao T, Tanaka K, Tamura D, Aomatsu K, Kudo K, et al. FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth. Cancer Res;70(5):2053-2063.
15. K. Matsumoto, T. Arao, K. Tanaka, H. Kaneda, K. Kudo, and Y. Fujita mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells Cancer Res 69 18 2009 7160 7164
16. K. Tanaka, T. Arao, M. Maegawa, K. Matsumoto, H. Kaneda, and K. Kudo SRPX2 is overexpressed in gastric cancer and promotes cellular migration and adhesion Int J Cancer 124 5 2009 1072 1080
17. H. Iwabuchi, M. Sakamoto, H. Sakunaga, Y.Y. Ma, M.L. Carcangiu, and D. Pinkel Genetic analysis of benign, low-grade, and high-grade ovarian tumors Cancer Res 55 24 1995 6172 6180
18. G. Sonoda, J. Palazzo, S. du Manoir, A.K. Godwin, M. Feder, and M. Yakushiji Comparative genomic hybridization detects frequent overrepresentation of chromosomal material from 3q26, 8q24, and 20q13 in human ovarian carcinomas Genes Chromosom Cancer 20 4 1997 320 328
19. M.M. Tanner, S. Grenman, A. Koul, O. Johannsson, P. Meltzer, and T. Pejovic Frequent amplification of chromosomal region 20q12-q13 in ovarian cancer Clin Cancer Res 6 5 2000 1833 1839
20. J. Hu, V. Khanna, M.W. Jones, and U. Surti Comparative study of primary and recurrent ovarian serous carcinomas: comparative genomic hybridization analysis with a potential application for prognosis Gynecol Oncol 89 3 2003 369 375
21. R.K. Srivastava, A.R. Srivastave, and Y.S. Cho-Chung Synergistic effects of 8-Cl-cAMP and retinoic acids in the inhibition of growth and induction of apoptosis in ovarian cancer cells: induction of retinoic acid receptor beta Mol Cell Biochem 204 1-2 2000 1 9
22. L. Yan, V. Herrmann, J.K. Hofer, and P.A. Insel beta-adrenergic receptor/cAMP-mediated signaling and apoptosis of S49 lymphoma cells Am J Physiol Cell Physiol 279 5 2000 C1665 C1674
23. E.H. Wu, B.H. Tam, and Y.H. Wong Constitutively active alpha subunits of G(q/11) and G(12/13) families inhibit activation of the pro-survival Akt signaling cascade FEBS J 273 11 2006 2388 2398
24. U.H. Frey, H. Alakus, J. Wohlschlaeger, K.J. Schmitz, G. Winde, and H.G. van Calker GNAS1 T393C polymorphism and survival in patients with sporadic colorectal cancer Clin Cancer Res 11 14 2005 5071 5077
25. U.H. Frey, A. Eisenhardt, G. Lummen, H. Rubben, K.H. Jockel, and K.W. Schmid The T393C polymorphism of the G alpha s gene (GNAS1) is a novel prognostic marker in bladder cancer Cancer Epidemiol Biomarkers Prev 14 4 2005 871 877
26. U.H. Frey, G. Lummen, T. Jager, K.H. Jockel, K.W. Schmid, and H. Rubben The GNAS1 T393C polymorphism predicts survival in patients with clear cell renal cell carcinoma Clin Cancer Res 12 3 Pt 1 2006 759 763
27. U.H. Frey, H. Nuckel, L. Sellmann, D. Siemer, R. Kuppers, and J. Durig The GNAS1 T393C polymorphism is associated with disease progression and survival in chronic lymphocytic leukemia Clin Cancer Res 12 19 2006 5686 5692