Pre-"EMT"ing key processes in liver carcinogenesis: Growing evidence for how malignant hepatocytes invade and conquer: Commentary

Hepatology

Volumn 52, Issue 1, 2010, Pages 384-388

  Teoh, Narci C ^a  

^a The Australian National University   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSATELLITE DNA; PROTEIN CDC42; RHO GUANINE NUCLEOTIDE BINDING PROTEIN;

CANCER CELL CULTURE; CANCER INVASION; CELL MIGRATION; CELL MOTILITY; CHROMATIN IMMUNOPRECIPITATION; DISEASE FREE SURVIVAL; EPITHELIAL MESENCHYMAL TRANSITION; GENE OVEREXPRESSION; IN VITRO STUDY; IN VIVO STUDY; LIVER CARCINOGENESIS; LIVER CELL; LIVER CELL CARCINOMA; METASTASIS; NOTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL;

EID: 77954239703     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.23777     Document Type: Note

References (33)

1. Bruix J, Boix J, Sala M, Llovet JM. Focus on HCC. Cancer Cell 2004;5:215-219.
2. Buendia MA. Genetics of hepatocellular carcinoma. Semin Cancer Biol 2000;10:185-200.
3. Haybaeck J, Zeller N, Wolf MJ, Weber A, Wagner U, Kurrer MO, et al. A lymphotoxin-driven pathway to hepatocellular carcinoma. Cancer Cell 2009;16:295-308.
4. Teoh N, Dan YY, Swisshelm K, Gu Y, Fausto N. Defective Ku70 DNA double strand break repair enhances hepatocarcinogenesis in mice. HEPATOLOGY 2008;47:2078-2088.
5. Moinzadeh P, Breuhahan K, Stutzer H, Schirmacher P. Chromosome alterations in human hepatocellular carcinoma correlate with aetiology and histological grade - results of an explorative CGH meta-analysis. Br J Cancer 2005;14:935-941.
6. Aihara T, Noguchi S, Sasaki Y, Nakano H, Monden M, Imaoka S. Clonal analysis of precancerous lesions of hepatocellular carcinoma. Gastroenterology 1996;111:455-461.
7. Nishimura T, Nishida N, Komeda T, Fukuda Y, Nakao K. Genotype stability and clonal evolution of hepatocellular carcinoma assessed by autopsy-based genome-wide microsatellite analysis. Cancer Genet Cytogenet 2005;161:164-169.
8. Matsubara K, Tokino T. Integration of hepatitis B virus DNA and its implications to hepatocarcinogenesis. Mol Biol Med 1990;7:243-260. (Pubitemid 20283937)
9. Ma NF, Hu L, Fung JM, Xie D, Zheng BJ, Chen L, et al. Isolation and characterization of a novel oncogene, amplified in liver cancer, within a commonly amplified region at 1q21 in hepatocellular carcinoma. HEPATOLOGY 2008;47:503-510.
10. Chen L, Chan THM, Yuan Y-F, Hu L, Huang J, Ma S, et al. CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients. J Clin Invest 2010;120:1178-1191.
11. Woodage T, Basrai MA, Baxevanis AD, Hieter P, Collins FS. Characterization of CHD family of proteins. Proc Natl Acad Sci USA 1997;94:11472-11477.
12. Chen M, Huan J-D, Hu L, Zheng B-J, Chen L, Tsang SL, et al. Transgenic CHD1L expression in mouse induces spontaneous tumors. PLoS ONE 2009;4:e6727.
13. Sahai E, Marchall CJ. RHO-GTPases and cancer. Nat Rev Cancer 2002;2:546-556.
14. Friedl P, Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer 2003;3:362-374.
15. Thiery JP, Acloque H, Huang RYJ, Nieto MA. Epithelial-mesenchymal transitions in development and disease. Cell 2009;139:871-890.
16. Jechlinger M, Grunert S, Tamir IH, Janda E, Ludeman S, Waerner T, et al. Expression profiling of epithelial plasticity in tumor progression. Oncogene 2003;22:7155-7169.
17. Nieto MA. The snail superfamily of zinc finger transcription factors. Nat Rev Mol Cell Biol 2002;3:155-166.
18. Yang J, Mani SA, Donaher JL, Ramaswany S, Itzykson RA, Come C, et al. Twist, a master regulator of morphogenesis, plays an essential role in tumor mestastasis. Cell 2004;117:927-939.
19. Penado H, Quintanilla M, Cano A. Transforming growth factor β-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions. J Bio Chem 2003;278:21113-21123.
20. Zhou BP, Deng J, Xia W, Xu J, Li YM, Gunduz M, et al. Dual regulation of Snail by GSK-3-β-mediated phosphoryltaion in control of epithelial mesenchymal transition. Nat Cell Biol 2004;6:931-940.
21. Sun T, Zhao N, Zhao XL, Gu Q, Zhang SW, Che N, et al. Expression and functional significance of Twist1 in hepatocellular carcinoma: its role in vasculogenic mimicry. HEPATOLOGY 2010;51:545-556.
22. Yang MH, Chen CL, Chau GY, Chiou SH, Su CW, Chou TY, et al. Comprehensive analysis of the independent effect of twist and snail in promoting metastasis of hepatocellular carcinoma. HEPATOLOGY 2009;50:1464-1474.
23. Matsuo N, Chiraha H, Fujikawa T, Takaoka N, Ueda N, Tanaka S, et al. Twist expression promotes migration and invasion in hepatocellular carcinoma. BMC Cancer 2009;9:240.
24. Lee TK, Man K, Poon RT, Lo CM, Yuen AP, Ng OI, et al. Signal transducers and activators of transcription 5b activation enhances hepatocellular carcinoma aggressiveness through induction of epithelial mesenchymal transition. Cancer Res 2006;66:9948-9956.
25. Pasca di Magliano M, Hebrok M. Hedgehog signalling in cancer formation and maintenance. Nat Rev Cancer 2003;3:903-911. (Pubitemid 37500175)
26. Sicklick JK, Li YX, Jayaraman A, Kannagai R, Qi Y, Vivekanandan P, et al. Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis. Carcinogenesis 2006;27:748-757.
27. Huang S, He J, Zhang X, Bian Y, Yang L, Xie G, et al. Activation of the hedgehog pathway in human hepatocellular carcinomas. Carcinogenesis 2006;27:1334-1340. (Pubitemid 43985408)
28. Branda M, Wands JR. Signal transduction cascades and hepatitis B and C related hepatocellular carcinoma. HEPATOLOGY 2006;43:891-902.
29. Merle P, de la Monte S, Kim M, Herrmann M, Tanaka S, Von dem Bussche A, et al. Functional consequences of frizzled-7 receptor overexpression in human hepatocellular carcinoma. Gastroenterology 2004;127:1110-1122.
30. Ishizaki Y, Ikeda S, Fujimori M, Shimizu Y, Kurihara T, Itamoto T, et al. Immunohistochemical analysis and mutational analyses of beta-catenin, Axin family and APC genes in hepatocellular carcinomas. Int J Oncol 2004;24:1077-1083.
31. Wells RG. The epithelial mesenchymal transition in liver fibrosis: here today, gone tomorrow? HEPATOLOGY 2010;51:737-740.
32. Zeisberg M, Yang C, Martino M, Duncan MB, Rieder F, Tanjore H, et al. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J Biol Chem 2007;282:23337-23347.
33. Taura K, Miura K, Iwaisako K, Osterreicher CH, Kodama Y, Penz-Osterreicher M, et al. Hepatocytes do not undergo epithelial mesenchymal transition in liver fibrosis in mice. HEPATOLOGY 2010;51:1027-1036.