Suppression of Akt1 phosphorylation by adenoviral transfer of the PTEN gene inhibits hypoxia-induced proliferation of rat pulmonary arterial smooth muscle cells

Biochemical and Biophysical Research Communications

Volumn 397, Issue 3, 2010, Pages 486-492

  Luo, Chunxia ^a   Yi, Bin ^a   Bai, Li ^a   Xia, Yongzhi ^a   Wang, Guansong ^a   Qian, Guisheng ^a   Feng, Hua ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Akt; Hypoxia; Proliferation; PTEN; Pulmonary artery; Smooth muscle

Indexed keywords

AKT 1 PROTEIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ADENOVIRUS; ANIMAL CELL; ANIMAL CELL CULTURE; ARTERY MUSCLE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE; GENETIC TRANSFECTION; HYPOXIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PULMONARY ARTERIAL SMOOTH MUSCLE CELL; PULMONARY ARTERY; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER;

ADENOVIRIDAE; ANIMALS; ANOXIA; CELL LINE; CELL PROLIFERATION; GENE TRANSFER TECHNIQUES; MYOCYTES, SMOOTH MUSCLE; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; PULMONARY ARTERY; RATS; SUPPRESSION, GENETIC;

ADENOVIRIDAE; RATTUS;

EID: 77954218088     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2010.05.140     Document Type: Article

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