메뉴 건너뛰기




Volumn 28, Issue 30, 2010, Pages 4802-4809

Potential use of a recombinant replication-defective adenovirus vector carrying the C-terminal portion of the P97 adhesin protein as a vaccine against Mycoplasma hyopneumoniae in swine

Author keywords

Mycoplasma hyopneumoniae; P97 adhesin; Porcine enzootic pneumonia; Replication defective adenovirus; Vaccination

Indexed keywords

ADENOVIRUS VECTOR; ADHESIN; BACTERIAL VACCINE; BACTERIN; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; P97 ADHESIN; SUBUNIT VACCINE; SUVAXYN; UNCLASSIFIED DRUG; CYTOKINE; IMMUNOGLOBULIN G; P97 PROTEIN, MYCOPLASMA; RECOMBINANT VACCINE;

EID: 77954216570     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.04.089     Document Type: Article
Times cited : (37)

References (43)
  • 1
    • 33846418986 scopus 로고    scopus 로고
    • Mycoplasmal diseases
    • Iowa State University Press, Ames, B.E. Straw, J. Zimmermann, S. D'Allaire, D.J. Taylor (Eds.)
    • Thacker E.L. Mycoplasmal diseases. Diseases of swine 2006, 700-713. Iowa State University Press, Ames. 9th ed. B.E. Straw, J. Zimmermann, S. D'Allaire, D.J. Taylor (Eds.).
    • (2006) Diseases of swine , pp. 700-713
    • Thacker, E.L.1
  • 2
    • 0028090196 scopus 로고
    • Ciliostasis and loss of cilia induced by Mycoplasma hyopneumoniae in porcine tracheal organ cultures
    • December (12)
    • DeBey M.C., Ross R.F. Ciliostasis and loss of cilia induced by Mycoplasma hyopneumoniae in porcine tracheal organ cultures. Infect Immun 1994, 62(December (12)):5312-5318.
    • (1994) Infect Immun , vol.62 , pp. 5312-5318
    • DeBey, M.C.1    Ross, R.F.2
  • 3
    • 0027648726 scopus 로고
    • Adherence of Mycoplasma hyopneumoniae to porcine ciliated respiratory tract cells
    • August (8)
    • Zielinski G.C., Ross R.F. Adherence of Mycoplasma hyopneumoniae to porcine ciliated respiratory tract cells. Am J Vet Res 1993, 54(August (8)):1262-1269.
    • (1993) Am J Vet Res , vol.54 , pp. 1262-1269
    • Zielinski, G.C.1    Ross, R.F.2
  • 4
    • 0033058350 scopus 로고    scopus 로고
    • Mycoplasma hyopneumoniae potentiation of porcine reproductive and respiratory syndrome virus-induced pneumonia
    • March (3)
    • Thacker E.L., Halbur P.G., Ross R.F., Thanawongnuwech R., Thacker B.J. Mycoplasma hyopneumoniae potentiation of porcine reproductive and respiratory syndrome virus-induced pneumonia. J Clin Microbiol 1999, 37(March (3)):620-627.
    • (1999) J Clin Microbiol , vol.37 , pp. 620-627
    • Thacker, E.L.1    Halbur, P.G.2    Ross, R.F.3    Thanawongnuwech, R.4    Thacker, B.J.5
  • 5
    • 77950688378 scopus 로고    scopus 로고
    • Development of a quantitative Real-Time TaqMan PCR assay for determination of the minimal dose of Mycoplasma hyopneumoniae strain 116 required to induce pneumonia in SPF pigs
    • May (5)
    • Marois C., Dory D., Fablet C., Madec F., Kobisch M. Development of a quantitative Real-Time TaqMan PCR assay for determination of the minimal dose of Mycoplasma hyopneumoniae strain 116 required to induce pneumonia in SPF pigs. J Appl Microbiol 2010, 108(May (5)):1523-1533.
    • (2010) J Appl Microbiol , vol.108 , pp. 1523-1533
    • Marois, C.1    Dory, D.2    Fablet, C.3    Madec, F.4    Kobisch, M.5
  • 6
    • 0034659604 scopus 로고    scopus 로고
    • Cytological and immunological changes in bronchoalveolar lavage fluid and histological observation of lung lesions in pigs immunized with Mycoplasma hyopneumoniae inactivated vaccine prepared from broth culture supernate
    • June (25)
    • Okada M., Asai T., Ono M., Sakano T., Sato S. Cytological and immunological changes in bronchoalveolar lavage fluid and histological observation of lung lesions in pigs immunized with Mycoplasma hyopneumoniae inactivated vaccine prepared from broth culture supernate. Vaccine 2000, 18(June (25)):2825-2831.
    • (2000) Vaccine , vol.18 , pp. 2825-2831
    • Okada, M.1    Asai, T.2    Ono, M.3    Sakano, T.4    Sato, S.5
  • 7
    • 29944437130 scopus 로고    scopus 로고
    • Cytokine expression in porcine lungs experimentally infected with Mycoplasma hyopneumoniae
    • February (3-4)
    • Lorenzo H., Quesada O., Assuncao P., Castro A., Rodriguez F. Cytokine expression in porcine lungs experimentally infected with Mycoplasma hyopneumoniae. Vet Immunol Immunopathol 2006, 109(February (3-4)):199-207.
    • (2006) Vet Immunol Immunopathol , vol.109 , pp. 199-207
    • Lorenzo, H.1    Quesada, O.2    Assuncao, P.3    Castro, A.4    Rodriguez, F.5
  • 8
    • 2442484041 scopus 로고    scopus 로고
    • Efficacy of vaccines against bacterial diseases in swine: what can we expect?
    • June (3-4)
    • Haesebrouck F., Pasmans F., Chiers K., Maes D., Ducatelle R., Decostere A. Efficacy of vaccines against bacterial diseases in swine: what can we expect?. Vet Microbiol 2004, 100(June (3-4)):255-268.
    • (2004) Vet Microbiol , vol.100 , pp. 255-268
    • Haesebrouck, F.1    Pasmans, F.2    Chiers, K.3    Maes, D.4    Ducatelle, R.5    Decostere, A.6
  • 10
    • 33644836224 scopus 로고    scopus 로고
    • Mucosal vaccines: the promise and the challenge
    • February (2)
    • Neutra M.R., Kozlowski P.A. Mucosal vaccines: the promise and the challenge. Nat Rev Immunol 2006, 6(February (2)):148-158.
    • (2006) Nat Rev Immunol , vol.6 , pp. 148-158
    • Neutra, M.R.1    Kozlowski, P.A.2
  • 11
    • 0025368887 scopus 로고
    • Identification and mapping of an immunogenic region of Mycoplasma hyopneumoniae p65 surface lipoprotein expressed in Escherichia coli from a cloned genomic fragment
    • August (8)
    • Kim M.F., Heidari M.B., Stull S.J., McIntosh M.A., Wise K.S. Identification and mapping of an immunogenic region of Mycoplasma hyopneumoniae p65 surface lipoprotein expressed in Escherichia coli from a cloned genomic fragment. Infect Immun 1990, 58(August (8)):2637-2643.
    • (1990) Infect Immun , vol.58 , pp. 2637-2643
    • Kim, M.F.1    Heidari, M.B.2    Stull, S.J.3    McIntosh, M.A.4    Wise, K.S.5
  • 12
    • 33746295322 scopus 로고    scopus 로고
    • Identification and immunological characterization of conserved Mycoplasma hyopneumoniae lipoproteins Mhp378 and Mhp651
    • August (1-3)
    • Meens J., Selke M., Gerlach G.F. Identification and immunological characterization of conserved Mycoplasma hyopneumoniae lipoproteins Mhp378 and Mhp651. Vet Microbiol 2006, 116(August (1-3)):85-95.
    • (2006) Vet Microbiol , vol.116 , pp. 85-95
    • Meens, J.1    Selke, M.2    Gerlach, G.F.3
  • 13
    • 0026027843 scopus 로고
    • Cloning and expression of a species-specific early immunogenic 36-kilodalton protein of Mycoplasma hyopneumoniae in Escherichia coli
    • April (4)
    • Strasser M., Frey J., Bestetti G., Kobisch M., Nicolet J. Cloning and expression of a species-specific early immunogenic 36-kilodalton protein of Mycoplasma hyopneumoniae in Escherichia coli. Infect Immun 1991, 59(April (4)):1217-1222.
    • (1991) Infect Immun , vol.59 , pp. 1217-1222
    • Strasser, M.1    Frey, J.2    Bestetti, G.3    Kobisch, M.4    Nicolet, J.5
  • 14
    • 0030020421 scopus 로고    scopus 로고
    • Molecular characterization of a ribonucleotide reductase (nrdF) gene fragment of Mycoplasma hyopneumoniae and assessment of the recombinant product as an experimental vaccine for enzootic pneumonia
    • March (3)
    • Fagan P.K., Djordjevic S.P., Eamens G.J., Chin J., Walker M.J. Molecular characterization of a ribonucleotide reductase (nrdF) gene fragment of Mycoplasma hyopneumoniae and assessment of the recombinant product as an experimental vaccine for enzootic pneumonia. Infect Immun 1996, 64(March (3)):1060-1064.
    • (1996) Infect Immun , vol.64 , pp. 1060-1064
    • Fagan, P.K.1    Djordjevic, S.P.2    Eamens, G.J.3    Chin, J.4    Walker, M.J.5
  • 15
    • 0028928377 scopus 로고
    • Identification and characterization of a Mycoplasma hyopneumoniae adhesin
    • March (3)
    • Zhang Q., Young T.F., Ross R.F. Identification and characterization of a Mycoplasma hyopneumoniae adhesin. Infect Immun 1995, 63(March (3)):1013-1019.
    • (1995) Infect Immun , vol.63 , pp. 1013-1019
    • Zhang, Q.1    Young, T.F.2    Ross, R.F.3
  • 16
    • 0034967825 scopus 로고    scopus 로고
    • Oral immunization of swine with attenuated Salmonella typhimurium aroA SL3261 expressing a recombinant antigen of Mycoplasma hyopneumoniae (NrdF) primes the immune system for a NrdF specific secretory IgA response in the lungs
    • February (2)
    • Fagan P.K., Walker M.J., Chin J., Eamens G.J., Djordjevic S.P. Oral immunization of swine with attenuated Salmonella typhimurium aroA SL3261 expressing a recombinant antigen of Mycoplasma hyopneumoniae (NrdF) primes the immune system for a NrdF specific secretory IgA response in the lungs. Microb Pathog 2001, 30(February (2)):101-110.
    • (2001) Microb Pathog , vol.30 , pp. 101-110
    • Fagan, P.K.1    Walker, M.J.2    Chin, J.3    Eamens, G.J.4    Djordjevic, S.P.5
  • 17
    • 0037449514 scopus 로고    scopus 로고
    • Vaccine efficacy of the attenuated Erysipelothrix rhusiopathiae YS-19 expressing a recombinant protein of Mycoplasma hyopneumoniae P97 adhesin against mycoplasmal pneumonia of swine
    • January (5-6)
    • Shimoji Y., Oishi E., Muneta Y., Nosaka H., Mori Y. Vaccine efficacy of the attenuated Erysipelothrix rhusiopathiae YS-19 expressing a recombinant protein of Mycoplasma hyopneumoniae P97 adhesin against mycoplasmal pneumonia of swine. Vaccine 2003, 21(January (5-6)):532-537.
    • (2003) Vaccine , vol.21 , pp. 532-537
    • Shimoji, Y.1    Oishi, E.2    Muneta, Y.3    Nosaka, H.4    Mori, Y.5
  • 18
    • 67649313322 scopus 로고    scopus 로고
    • Oral vaccination against mycoplasmal pneumonia of swine using a live Erysipelothrix rhusiopathiae vaccine strain as a vector
    • July (33)
    • Ogawa Y., Oishi E., Muneta Y., Sano A., Hikono H., Shibahara T., et al. Oral vaccination against mycoplasmal pneumonia of swine using a live Erysipelothrix rhusiopathiae vaccine strain as a vector. Vaccine 2009, 27(July (33)):4543-4550.
    • (2009) Vaccine , vol.27 , pp. 4543-4550
    • Ogawa, Y.1    Oishi, E.2    Muneta, Y.3    Sano, A.4    Hikono, H.5    Shibahara, T.6
  • 19
    • 0031877531 scopus 로고    scopus 로고
    • Reiterated repeat region variability in the ciliary adhesin gene of Mycoplasma hyopneumoniae
    • July (Pt 7)
    • Wilton J.L., Scarman A.L., Walker M.J., Djordjevic S.P. Reiterated repeat region variability in the ciliary adhesin gene of Mycoplasma hyopneumoniae. Microbiology 1998, 144(July (Pt 7)):1931-1943.
    • (1998) Microbiology , vol.144 , pp. 1931-1943
    • Wilton, J.L.1    Scarman, A.L.2    Walker, M.J.3    Djordjevic, S.P.4
  • 20
    • 33846447881 scopus 로고    scopus 로고
    • Interactions of highly and low virulent Mycoplasma hyopneumoniae isolates with the respiratory tract of pigs
    • February (1-2)
    • Meyns T., Maes D., Calus D., Ribbens S., Dewulf J., Chiers K., et al. Interactions of highly and low virulent Mycoplasma hyopneumoniae isolates with the respiratory tract of pigs. Vet Microbiol 2007, 120(February (1-2)):87-95.
    • (2007) Vet Microbiol , vol.120 , pp. 87-95
    • Meyns, T.1    Maes, D.2    Calus, D.3    Ribbens, S.4    Dewulf, J.5    Chiers, K.6
  • 21
    • 3543094353 scopus 로고    scopus 로고
    • Identification of the cilium binding epitope of the Mycoplasma hyopneumoniae P97 adhesin
    • October (10)
    • Hsu T., Minion F.C. Identification of the cilium binding epitope of the Mycoplasma hyopneumoniae P97 adhesin. Infect Immun 1998, 66(October (10)):4762-4766.
    • (1998) Infect Immun , vol.66 , pp. 4762-4766
    • Hsu, T.1    Minion, F.C.2
  • 22
    • 0034103536 scopus 로고    scopus 로고
    • R1 region of P97 mediates adherence of Mycoplasma hyopneumoniae to swine cilia
    • May (5)
    • Minion F.C., Adams C., Hsu T. R1 region of P97 mediates adherence of Mycoplasma hyopneumoniae to swine cilia. Infect Immun 2000, 68(May (5)):3056-3060.
    • (2000) Infect Immun , vol.68 , pp. 3056-3060
    • Minion, F.C.1    Adams, C.2    Hsu, T.3
  • 24
    • 0031671014 scopus 로고    scopus 로고
    • Induction of immunity in the respiratory tract and protection from bovine herpesvirus type 1 infection by different routes of immunization with recombinant adenovirus
    • Papp Z., Babiuk L.A., Baca-Estrada M.E. Induction of immunity in the respiratory tract and protection from bovine herpesvirus type 1 infection by different routes of immunization with recombinant adenovirus. Viral Immunol 1998, 11(2):79-91.
    • (1998) Viral Immunol , vol.11 , Issue.2 , pp. 79-91
    • Papp, Z.1    Babiuk, L.A.2    Baca-Estrada, M.E.3
  • 25
    • 0028864302 scopus 로고
    • Induction of antibodies protecting against transmissible gastroenteritis coronavirus (TGEV) by recombinant adenovirus expressing TGEV spike protein
    • November (2)
    • Torres J.M., Sanchez C., Sune C., Smerdou C., Prevec L., Graham F., et al. Induction of antibodies protecting against transmissible gastroenteritis coronavirus (TGEV) by recombinant adenovirus expressing TGEV spike protein. Virology 1995, 213(November (2)):503-516.
    • (1995) Virology , vol.213 , pp. 503-516
    • Torres, J.M.1    Sanchez, C.2    Sune, C.3    Smerdou, C.4    Prevec, L.5    Graham, F.6
  • 27
    • 0023122268 scopus 로고
    • Growth of 293 cells in suspension culture
    • March (3)
    • Graham F.L. Growth of 293 cells in suspension culture. J Gen Virol 1987, 68(March (Pt 3)):937-940.
    • (1987) J Gen Virol , vol.68 , Issue.PART , pp. 937-940
    • Graham, F.L.1
  • 28
    • 17344373287 scopus 로고    scopus 로고
    • New helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses
    • September (13)
    • Fallaux F.J., Bout A., van der Velde I., van den Wollenberg D.J., Hehir K.M., Keegan J., et al. New helper cells and matched early region 1-deleted adenovirus vectors prevent generation of replication-competent adenoviruses. Hum Gene Ther 1998, 9(September (13)):1909-1917.
    • (1998) Hum Gene Ther , vol.9 , pp. 1909-1917
    • Fallaux, F.J.1    Bout, A.2    van der Velde, I.3    van den Wollenberg, D.J.4    Hehir, K.M.5    Keegan, J.6
  • 29
    • 34547116175 scopus 로고    scopus 로고
    • Immune responses induced by replication-defective adenovirus expressing the C-terminal portion of the Mycoplasma hyopneumoniae P97 adhesin
    • June (6)
    • Okamba F.R., Moreau E., Cheikh Saad Bouh K., Gagnon C.A., Massie B., Arella M. Immune responses induced by replication-defective adenovirus expressing the C-terminal portion of the Mycoplasma hyopneumoniae P97 adhesin. Clin Vaccine Immunol 2007, 14(June (6)):767-774.
    • (2007) Clin Vaccine Immunol , vol.14 , pp. 767-774
    • Okamba, F.R.1    Moreau, E.2    Cheikh Saad Bouh, K.3    Gagnon, C.A.4    Massie, B.5    Arella, M.6
  • 30
    • 54849432802 scopus 로고    scopus 로고
    • Diseases of the respiratory system
    • Iowa State University Press, Ames, B.E. Straw, J. Zimmermann, S. D'Allaire, D.J. Taylor (Eds.)
    • Sorensen V., Jorsal S.V., Mousing J. Diseases of the respiratory system. Diseases of swine 2006, 149-177. Iowa State University Press, Ames. 9th ed. B.E. Straw, J. Zimmermann, S. D'Allaire, D.J. Taylor (Eds.).
    • (2006) Diseases of swine , pp. 149-177
    • Sorensen, V.1    Jorsal, S.V.2    Mousing, J.3
  • 31
    • 0034063150 scopus 로고    scopus 로고
    • Role of Bordetella bronchiseptica fimbriae in tracheal colonization and development of a humoral immune response
    • April (4)
    • Mattoo S., Miller J.F., Cotter P.A. Role of Bordetella bronchiseptica fimbriae in tracheal colonization and development of a humoral immune response. Infect Immun 2000, 68(April (4)):2024-2033.
    • (2000) Infect Immun , vol.68 , pp. 2024-2033
    • Mattoo, S.1    Miller, J.F.2    Cotter, P.A.3
  • 32
    • 37849023420 scopus 로고    scopus 로고
    • Intranasal administration of a recombinant adenovirus expressing the norovirus capsid protein stimulates specific humoral, mucosal, and cellular immune responses in mice
    • January (4)
    • Guo L., Wang J., Zhou H., Si H., Wang M., Song J., et al. Intranasal administration of a recombinant adenovirus expressing the norovirus capsid protein stimulates specific humoral, mucosal, and cellular immune responses in mice. Vaccine 2008, 26(January (4)):460-468.
    • (2008) Vaccine , vol.26 , pp. 460-468
    • Guo, L.1    Wang, J.2    Zhou, H.3    Si, H.4    Wang, M.5    Song, J.6
  • 33
    • 0141570410 scopus 로고    scopus 로고
    • Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system
    • September (18)
    • Lemiale F., Kong W.P., Akyurek L.M., Ling X., Huang Y., Chakrabarti B.K., et al. Enhanced mucosal immunoglobulin A response of intranasal adenoviral vector human immunodeficiency virus vaccine and localization in the central nervous system. J Virol 2003, 77(September (18)):10078-10087.
    • (2003) J Virol , vol.77 , pp. 10078-10087
    • Lemiale, F.1    Kong, W.P.2    Akyurek, L.M.3    Ling, X.4    Huang, Y.5    Chakrabarti, B.K.6
  • 34
    • 0141958135 scopus 로고    scopus 로고
    • Mucosally delivered E1-deleted adenoviral vaccine carriers induce transgene product-specific antibody responses in neonatal mice
    • October (8)
    • Xiang Z., Li Y., Gao G., Wilson J.M., Ertl H.C. Mucosally delivered E1-deleted adenoviral vaccine carriers induce transgene product-specific antibody responses in neonatal mice. J Immunol 2003, 171(October (8)):4287-4293.
    • (2003) J Immunol , vol.171 , pp. 4287-4293
    • Xiang, Z.1    Li, Y.2    Gao, G.3    Wilson, J.M.4    Ertl, H.C.5
  • 35
    • 0023733838 scopus 로고
    • Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells
    • July (6179)
    • Stevens T.L., Bossie A., Sanders V.M., Fernandez-Botran R., Coffman R.L., Mosmann T.R., et al. Regulation of antibody isotype secretion by subsets of antigen-specific helper T cells. Nature 1988, 334(July (6179)):255-258.
    • (1988) Nature , vol.334 , pp. 255-258
    • Stevens, T.L.1    Bossie, A.2    Sanders, V.M.3    Fernandez-Botran, R.4    Coffman, R.L.5    Mosmann, T.R.6
  • 36
    • 0031020759 scopus 로고    scopus 로고
    • Characterization of the gene encoding Mhp1 from Mycoplasma hyopneumoniae and examination of Mhp1's vaccine potential
    • January (1)
    • King K.W., Faulds D.H., Rosey E.L., Yancey R.J. Characterization of the gene encoding Mhp1 from Mycoplasma hyopneumoniae and examination of Mhp1's vaccine potential. Vaccine 1997, 15(January (1)):25-35.
    • (1997) Vaccine , vol.15 , pp. 25-35
    • King, K.W.1    Faulds, D.H.2    Rosey, E.L.3    Yancey, R.J.4
  • 37
    • 3142529145 scopus 로고    scopus 로고
    • Comparison of antibody production, lymphocyte stimulation, and protection induced by four commercial Mycoplasma hyopneumoniae bacterins
    • Thacker E.L., Thacker B.J., Boettcher T.B., Jayappa H. Comparison of antibody production, lymphocyte stimulation, and protection induced by four commercial Mycoplasma hyopneumoniae bacterins. Swine Health Prod 1998, 6:107-112.
    • (1998) Swine Health Prod , vol.6 , pp. 107-112
    • Thacker, E.L.1    Thacker, B.J.2    Boettcher, T.B.3    Jayappa, H.4
  • 38
    • 0027365716 scopus 로고
    • Serum and mucosal antibody responses against Mycoplasma hyopneumoniae following intraperitoneal vaccination and challenge of pigs with M hyopneumoniae
    • November (3)
    • Sheldrake R.F., Romalis L.F., Saunders M.M. Serum and mucosal antibody responses against Mycoplasma hyopneumoniae following intraperitoneal vaccination and challenge of pigs with M hyopneumoniae. Res Vet Sci 1993, 55(November (3)):371-376.
    • (1993) Res Vet Sci , vol.55 , pp. 371-376
    • Sheldrake, R.F.1    Romalis, L.F.2    Saunders, M.M.3
  • 39
    • 0141992681 scopus 로고    scopus 로고
    • A morphologic and immunohistochemical study of the bronchus-associated lymphoid tissue of pigs naturally infected with Mycoplasma hyopneumoniae
    • July (4)
    • Sarradell J., Andrada M., Ramirez A.S., Fernandez A., Gomez-Villamandos J.C., Jover A., et al. A morphologic and immunohistochemical study of the bronchus-associated lymphoid tissue of pigs naturally infected with Mycoplasma hyopneumoniae. Vet Pathol 2003, 40(July (4)):395-404.
    • (2003) Vet Pathol , vol.40 , pp. 395-404
    • Sarradell, J.1    Andrada, M.2    Ramirez, A.S.3    Fernandez, A.4    Gomez-Villamandos, J.C.5    Jover, A.6
  • 40
    • 0022155102 scopus 로고
    • Suppressive effect of nonviable Mycoplasma hyopneumoniae on phytohemagglutinin-induced transformation of swine lymphocytes
    • November (11)
    • Kishima M., Ross R.F. Suppressive effect of nonviable Mycoplasma hyopneumoniae on phytohemagglutinin-induced transformation of swine lymphocytes. Am J Vet Res 1985, 46(November (11)):2366-2368.
    • (1985) Am J Vet Res , vol.46 , pp. 2366-2368
    • Kishima, M.1    Ross, R.F.2
  • 41
    • 0038384091 scopus 로고    scopus 로고
    • Characterization of the immune response to Mycoplasma bovis lung infection
    • July (1-2)
    • Vanden Bush T.J., Rosenbusch R.F. Characterization of the immune response to Mycoplasma bovis lung infection. Vet Immunol Immunopathol 2003, 94(July (1-2)):23-33.
    • (2003) Vet Immunol Immunopathol , vol.94 , pp. 23-33
    • Vanden Bush, T.J.1    Rosenbusch, R.F.2
  • 43
    • 4644221965 scopus 로고    scopus 로고
    • Increased production of proinflammatory cytokines following infection with porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae
    • September (5)
    • Thanawongnuwech R., Thacker B., Halbur P., Thacker E.L. Increased production of proinflammatory cytokines following infection with porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae. Clin Diagn Lab Immunol 2004, 11(September (5)):901-908.
    • (2004) Clin Diagn Lab Immunol , vol.11 , pp. 901-908
    • Thanawongnuwech, R.1    Thacker, B.2    Halbur, P.3    Thacker, E.L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.