Reduced serum levels of 25-hydroxy and 1,25-dihydroxy vitamin D in Egyptian children with autism

Journal of Alternative and Complementary Medicine

Volumn 16, Issue 6, 2010, Pages 641-645

  Meguid, Nagwa A ^a   Hashish, Adel F ^a   Anwar, Mona ^a   Sidhom, Gloria ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIFEDIOL; CALCITRIOL; CALCIUM;

ARTICLE; AUTISM; CALCIUM BLOOD LEVEL; CASE CONTROL STUDY; CHILD; CLINICAL ASSESSMENT; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSS-SECTIONAL STUDY; DEMOGRAPHY; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE ASSOCIATION; EGYPT; HUMAN; MAJOR CLINICAL STUDY; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SOCIAL STATUS;

AUTISTIC DISORDER; CALCITRIOL; CALCIUM; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; EGYPT; HUMANS; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 77954201681     PISSN: 10755535     EISSN: None     Source Type: Journal    
DOI: 10.1089/acm.2009.0349     Document Type: Article

References (43)

1. Holick MF. High prevalence for vitamin D inadequacy and implications for health. Mayo Clin Proc 2006;81:353-373.
2. Peterlik M, Cross HS. Vitamin D and calcium deficits predispose for multiple chronic diseases. Eur J Clin Invest 2005;35:290-304.
3. Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr 2004;80:1678S-1688S.
4. Zittermann A. Vitamin D in preventive medicine: Are we ignoring the evidence? Br J Nutr 2003;89:552-572.
5. Peterlik M, Cross HS. Dysfunction of the vitamin D endocrine system as common cause for multiple malignant and other chronic diseases. Anticancer Res 2006;26:2581-2588.
6. Aloia J, Li-Ng M. Re: Epidemic influenza and vitamin D. Epidemiol Infect 2007;135:1095-1096; author reply 1097-1098.
7. Cannell JJ. Autism and vitamin D. Med Hypotheses 2008;70: 750-759.
8. Litonjua AA, Weiss ST. Is vitamin D deficiency to blame for the asthma epidemic? J Allergy Clin Immunol 2007;120: 1031-1035.
9. Cannell JJ, Hollis BW. Use of vitamin D in clinical practice. Altern Med Rev 2008;13:6-20.
10. Lips P. Vitamin D physiology. Prog Biophys Mol Biol 2006;92:4-8.
11. Zehnder D, Bland R, Williams MC, et al. Extrarenal expression of 25-hydroxyvitamin D3-1a-hydroxylase. J Clin Endocrinol Metab 2001;86:888-894.
12. Garcion E, Wion-Barbot N, Montero-Menei CN, et al. New clues about vitamin D functions in the nervous system. Trends Endocrinol Metab 2002;13:100-105.
13. Fombonne E. The prevalence of autism. JAMA 2003;289: 87-89.
14. McGrath J, Feron F, Eyles D, Mackay-Sim A. Vitamin D: The neglected neurosteroid? Trends Neurosci 2001;24: 570-572.
15. Kalueff AV, Minasyan A, Keisala T, et al. The vitamin D neuroendocrine system as a target for novel neurotropic drugs. CNS Neurol Disord Drug Targets 2006;5:363-371.
16. Kalueff AV, Tuohimaa P. Neurosteroid hormone vitamin D and its utility in clinical nutrition. Curr Opin Clin Nutr Metab Care 2007;10:12-19.
17. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. Washington, DC: American Psychiatric Association, 1994.
18. Lord C, Rutter M, Le Couteur A. Autism Diagnostic Interview-Revised: A revised version of diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord 1994;24: 659-685.
19. Herndon AC, DiGuiseppi C, Johnson SL, et al. Does nutritional intake differ between children with autism spectrum disorders and children with typical development? J Autism Dev Disord 2009;39:212-222.
20. Bischoff-Ferrari H, Dietrich T, Orav E, Dawson-Hughes B. Positive association between 25(OH)D levels and bone mineral density: A population-based study of younger and older adults. Am J Med 2004;116:634-639.
21. Fuleihan E, Nabulsi M, Tamim H, et al. Effect of vitamin D replacement on musculoskeletal parameters in school children: A randomized controlled trial. J Clin Endocrinal Metab 2006;91:405-412.
22. Javaid M, Crozier S, Harvey N, et al. Maternal vitamin D status during pregnancy and childhood bone mass at 9 years: A longitudinal study. Lancet 2006;367:36-43.
23. Heaney R, Dowell M, Hale C, Bendich A. Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. J Am Coll Nutr 2003;22:142-146.
24. Visser M, Deeg D, Lips P. Low vitamin D and high parathyroid hormone levels as determinants of loss of muscle strength and muscle mass (sarcopenia): The longitudinal aging study Amsterdam. J Clin Endocrinal Metab 2003;88: 5766-5772.
25. Vieth R, Ladak Y, Walfish P. Age-related changes in the 25- hydroxyvitamin D versus parathyroid hormone relationship suggest a different reason why older adults require more vitamin D. J Clin Endocrinal Metab 2003;88:185-191.
26. Hollis BW. Circulating 25-hydroxyvitamin D levels indicative of vitamin sufficiency: Implications for establishing a new effective DRI for vitamin D. J Nutr 2005;135:317-322.
27. Hollis BW, Wagner CL, Drezner MK, Binkley NC. Circulating vitamin D3 and 25-hydroxyvitamin D in humans: An important tool to define adequate nutritional vitamin D status. J Steroid Biochem Mol Biol 2007;103(3-5):631-634.
28. Holick MF. Vitamin D status: Measurement, interpretation, and clinical application. Ann Epidemiol 2009;19:73-78.
29. Vieth R. What is the optimal vitamin D status for health? Prog Biophys Mol Biol 2006;92:26-32.
30. Ko P, Burkert R, McGrath J, Eyles D. Maternal vitamin D3 deprivation and the regulation of apoptosis and cell cycle during rat brain development. Brain Res Dev Brain Res 2004;153:61-68.
31. Feron F, Burne TH, Brown J, et al. Developmental vitamin D3 deficiency alters the adult rat brain. Brain Res Bull 2005;65:141-148.
32. Burne TH, Becker A, Brown J, et al. Transient prenatal vitamin D deficiency is associated with hyperlocomotion in adult rats. Behav Brain Res 2004;154:549-555.
33. Becker A, Eyles DW, McGrath JJ, Grecksch G. Transient prenatal vitamin D deficiency is associated with subtle alterations in learning and memory functions in adult rats. Behav Brain Res 2005;161:306-312.
34. Almeras L, Eyles D, Benech P, et al. Developmental vitamin D deficiency alters brain protein expression in the adult rat: Implications for neuropsychiatric disorders. Proteomics 2007;7:769-780. (Pubitemid 46450654)
35. Eyles D, Brown J, Mackay-Sim A, et al. Vitamin D3 and brain development. Neuroscience 2003;118:641-653.
36. Piven J, Arndt S, Bailey J, et al. An MRI study of brain size in autism. Am J Psychiatry1995;152:1145-1149.
37. Hardan AY, Minshew NJ, Mallikarjuhn M, Keshavan MS. Brain volume in autism. J Child Neurol 2001;16:421-424.
38. Ashwood P, Wills S, Van de Water J. The immune response in autism: A new frontier for autism research. J Leukoc Biol 2006;80:1-15.
39. Moore ME, Piazza A, McCartney Y, Lynch MA. Evidence that vitamin D3 reverses age-related inflammatory changes in the rat hippocampus. Biochem Soc Trans 2005;33(pt 4):573-577.
40. Rossi PG, Parmeggiani A, Bach V, et al. EEG features and epilepsy in patients with autism. Brain Dev 1995;17:169-174.
41. Siegel A, Malkowitz L, Moskovits MJ, Christakos S. Administration of 1,25-dihydroxyvitamin D3 results in the elevation of hippocampal seizure threshold levels in rats. Brain Res 1984;298:125-129. (Pubitemid 14135610)
42. Eyles DW, Smith S, Kinobe R, et al. Distribution of the vitamin D receptor and 1a-hydroxylase in human brain. J Chem Neuroanat 2005;29:21-30.
43. Stevens MC, Fein DH, Waterhouse LH. Season of birth effects in autism. J Clin Exp Neuropsychol 2000;22:399-407.