Androgen profiles during pubertal Leydig cell development in mice

Reproduction

Volumn 140, Issue 1, 2010, Pages 113-121

  Wu, Xiufeng ^a   Arumugam, Ramamani ^b   Zhang, Ningning ^a   Lee, Mary M ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROSTANEDIOL; ANDROSTENEDIONE; CYTOCHROME P450; LUTEINIZING HORMONE; STEROID 17ALPHA MONOOXYGENASE; TESTOSTERONE; MESSENGER RNA; STEROID;

ANDROGEN BLOOD LEVEL; ANDROGEN SYNTHESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL LINEAGE; CELL MATURATION; CONTROLLED STUDY; GENE EXPRESSION; HORMONE SYNTHESIS; IN VITRO STUDY; LEYDIG CELL; LUTEINIZING HORMONE BLOOD LEVEL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUBERTY; RAT; SEXUAL MATURATION; STEROIDOGENESIS; AGING; ANIMAL; BIOSYNTHESIS; CELL SEPARATION; CYTOLOGY; DRUG EFFECTS; FEMALE; GENETICS; GROWTH, DEVELOPMENT AND AGING; IMMUNOHISTOCHEMISTRY; METABOLISM; NORTHERN BLOTTING; PHYSIOLOGY; PREGNANCY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STIMULATION; TESTIS; TRANSGENIC MOUSE;

MURINAE; MUS; RATTUS;

AGING; ANDROGENS; ANIMALS; BLOTTING, NORTHERN; CELL DIFFERENTIATION; CELL SEPARATION; FEMALE; IMMUNOHISTOCHEMISTRY; LEYDIG CELLS; LUTEINIZING HORMONE; MALE; MICE; MICE, TRANSGENIC; PREGNANCY; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SEXUAL MATURATION; STEROIDS; STIMULATION, CHEMICAL; TESTIS;

EID: 77954194020     PISSN: 14701626     EISSN: 17417899     Source Type: Journal    
DOI: 10.1530/REP-09-0349     Document Type: Article

References (37)

1. Ariyaratne HB & Chamindrani Mendis-Handagama S 2000 Changes in the testis interstitium of Sprague-Dawley rats from birth to sexual maturity. Biology of Reproduction 62 680-690.
2. Baker PJ, Sha JH & O'Shaughnessy PJ 1997 Localisation and regulation of 17β-hydroxysteroid dehydrogenase type 3 mRNA during development in the mouse testis. Molecular and Cellular Endocrinology 133 127-133.
3. Baker PJ, Pakarinen P, Huhtaniemi IT, Abel MH, Charlton HM, Kumar TR & O'Shaughnessy PJ 2003 Failure of normal Leydig cell development in follicle-stimulating hormone (FSH) receptor-deficient mice, but not FSHβ-deficient mice: role for constitutive FSH receptor activity. Endocrinology 144 138-145.
4. Benton L, Shan LX & Hardy MP 1995 Differentiation of adult Leydig cells. Journal of Steroid Biochemistry and Molecular Biology 53 61-68.
5. Cochran RC, Schuetz AW & Ewing LL 1979 Age-related changes in conversion of 5α-androstan-17β-ol-3-one to 5α-androstane- 3α,17β-diol and 5α-androstane-3β,17β-diol by rat testicular cells in vitro. Journal of Reproduction and Fertility 57 143-147.
6. Cochran R, Ewing L & Niswender G 1981 Serum levels of follicle stimulating hormone, luteinizing hormone, prolactin, testosterone, 5α-dihydrotestosterone, 5α-androstane-3α, 17β-diol, 5α-androstane-3β-, 17β-diol, and 17β-estradiol from male beagles with spontaneous or induced benign prostatic hyperplasia. Investigative Urology 19 142-147. (Pubitemid 12236414)
7. Coffey JC, French FS & Nayfeh SN 1971 Metabolism of progesterone by rat testicular homogenates. IV. Further studies of testosterone formation in immature testis in vitro. Endocrinology 89 865-872.
8. Dong L, Jelinsky SA, Finger JN, Johnston DS, Kopf GS, Sottas CM, Hardy MP & Ge RS 2007 Gene expression during development of fetal and adult Leydig cells. Annals of the New York Academy of Sciences 1120 16-35.
9. Ge R & Hardy MP 1998 Variation in the end products of androgen biosynthesis and metabolism during postnatal differentiation of rat Leydig cells. Endocrinology 139 3787-3795.
10. Ge RS, Shan LX & Hardy MP 1996 Pubertal development of Leydig cells. In The Ledig Cell, edn 1, pp 159-174. Eds AH Payne, MP Hardy & LD Russell. Vienna: Cache River Press.
11. Gondos B, Morrison KP & Renston RH 1977 Leydig cell differentiation in the prepubertal rabbit testis. Biology of Reproduction 17 745-748. (Pubitemid 8245388)
12. Hardy MP, Zirkin BR & Ewing LL 1989 Kinetic studies on the development of the adult population of Leydig cells in testes of the pubertal rat. Endocrinology 124 762-770.
13. Kerr JB & Knell CM 1988 The fate of fetal Leydig cells during the development of the fetal and postnatal rat testis. Development 103 535-544.
14. Killian J, Pratis K, Clifton RJ, Stanton PG, Robertson DM & O'Donnell L 2003 5a-reductase isoenzymes 1 and 2 in the rat testis during postnatal development. Biology of Reproduction 68 1711-1718.
15. Klinefelter GR, Hall PF & Ewing LL 1987 Effect of luteinizing hormone deprivation in situ on steroidogenesis of rat Leydig cells purified by a multistep procedure. Biology of Reproduction 36 769-783.
16. Klinefelter GR, Kelce WR & Hardy MP 1993 Isolation and culture of Leydig cells from adult rats. In Methods in Reproductive Toxicology, pp 166-181. Eds J Heindel & RE Chaplin. San Diego, CA, USA: Academic Press.
17. Kuopio T, Paranko J & Pelliniemi LJ 1989 Basement membrane and epithelial features of fetal-type Leydig cells in rat and human testis. Differentiation 40 198-206. (Pubitemid 19198278)
18. Livak KJ & Schmittgen TD 2001 Analysis of relative gene expression data using real-time quantitative PCR and the 2(KDelta Delta C(T)) method. Methods 25 402-408.
19. Mendis-Handagama SM, Risbridger GP & de Kretser DM 1987 Morphometric analysis of the components of the neonatal and the adult rat testis interstitium. International Journal of Andrology 10 525-534.
20. Mendis-Handagama SM, Ariyaratne HB, Teunissen van Manen KR & Haupt RL 1998 Differentiation of adult Leydig cells in the neonatal rat testis is arrested by hypothyroidism. Biology of Reproduction 59 351-357.
21. Nef S, Shipman T & Parada LF 2000 A molecular basis for estrogen-induced cryptorchidism. Developmental Biology 224 354-361.
22. O'Shaughnessy PJ, Baker PJ, Heikkila M, Vainio S & McMahon AP 2000 Localization of 17β-hydroxysteroid dehydrogenase/17-ketosteroid reductase isoform expression in the developing mouse testis - androstenedione is the major androgen secreted by fetal/neonatal leydig cells. Endocrinology 141 2631-2637.
23. O'Shaughnessy PJ, Willerton L & Baker PJ 2002 Changes in Leydig cell gene expression during development in the mouse. Biology of Reproduction 66 966-975. (Pubitemid 34263116)
24. Payne AH & Hales DB 2004 Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones. Endocrine Reviews 25 947-970.
25. Payne AH, Downing JR & Wong KL 1980 Luteinizing hormone receptors and testosterone synthesis in two distinct populations of Leydig cells. Endocrinology 106 1424-1429.
26. Rasmussen R 2001 Quantification on the LightCycler. In Rapid Cycle Real-Time PCR, Methods and Applications, pp 21-34. Eds S Meuer, C Wittwer & K Nakagawara. Heidelberg: Springer Press.
27. Salva A, Klinefelter GR & Hardy MP 2001 Purification of rat leydig cells: increased yields after unit-gravity sedimentation of collagenase- dispersed interstitial cells. Journal of Andrology 22 665-671. (Pubitemid 32623086)
28. Shan LX, Phillips DM, Bardin CW & Hardy MP 1993 Differential regulation of steroidogenic enzymes during differentiation optimizes testosterone production by adult rat Leydig cells. Endocrinology 133 2277-2283.
29. Sheffield JW & O'Shaughnessy PJ 1988 Testicular steroid metabolism during development in the normal and hypogonadal mouse. Journal of Endocrinology 119 257-264.
30. Vergouwen RP, Jacobs SG, Huiskamp R, Davids JA & de Rooij DG 1991 Proliferative activity of gonocytes, Sertoli cells and interstitial cells during testicular development in mice. Journal of Reproduction and Fertility 93 233-243.
31. Vergouwen RP, Huiskamp R, Bas RJ, Roepers-Gajadien HL, Davids JA & de Rooij DG 1993 Postnatal development of testicular cell populations in mice. Journal of Reproduction and Fertility 99 479-485. (Pubitemid 24051994)
32. Viger RS & Robaire B 1995 Steady state steroid 5a-reductase messenger ribonucleic acid levels and immunocytochemical localization of the type 1 protein in the rat testis during postnatal development. Endocrinology 136 5409-5415.
33. Weinstein A, Lindner HR, Friedlander A & Bauminger S 1972 Antigenic complexes of steroid hormones formed by coupling to protein through position 7: preparation from 4-3-oxosteroids and characterization of antibodies to testosterone and androstenedione. Steroids 20 789-812.
34. Welsh MJ & Wiebe JP 1978 Sertoli cell capacity to metabolize C19 steroids: variation with age and the effect of follicle-stimulating hormone. Endocrinology 103 838-844.
35. Wu X, Arumugam R, Baker SP & Lee MM 2005 Pubertal and adult Leydig cell function in Mullerian inhibiting substance-deficient mice. Endocrinology 146 589-595.
36. Wu X, Wan S & Lee MM 2007 Key factors in the regulation of fetal and postnatal Leydig cell development. Journal of Cellular Physiology 213 429-433.
37. Zamecnik J, Barbe G, Moger WH & Armstrong DT 1977 Radioimmuno-assays for androsterone, 5α-androstane-3α, 17β-diol and 5α-androstane- 3β, 17β-diol. Steroids 30 679-689.