Loss of a DNA binding site within the tail of prelamin A contributes to altered heterochromatin anchorage by progerin

FEBS Letters

Volumn 584, Issue 14, 2010, Pages 2999-3004

  Bruston, Francine ^a   Delbarre, Erwan ^b   Östlund, Cecilia ^c   Worman, Howard J ^c   Buendia, Brigitte ^a   Duband Goulet, Isabelle ^a  

^a Groupe Hospitalier Pitié Salpêtrière   (France)

^b UNIVERSITY OF OSLO   (Norway)

^c Columbia University ^*  (United States)

Author keywords

Chromatin; Histone methylation; Lamins; Premature senescence; Protein interaction

Indexed keywords

AMINO ACID; DNA; GLUTATHIONE; HISTONE; HYBRID PROTEIN; LAMIN A; LAMIN C; PRELAMIN A; PROGERIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; LAMIN; NUCLEAR PROTEIN; PROTEIN PRECURSOR;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CHROMATIN; CONTROLLED STUDY; DNA BINDING; GEL MOBILITY SHIFT ASSAY; GENE MUTATION; HETEROCHROMATIN; IN VITRO STUDY; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROGERIA; PROTEIN DNA INTERACTION; PROTEIN EXPRESSION; SURFACE PLASMON RESONANCE; WILD TYPE; ANIMAL; GENE DELETION; GENETICS; GENOTYPE; HUMAN; METABOLISM; MOUSE; MUTATION; TRANSGENIC MOUSE;

ANIMALS; BINDING SITES; CHROMATIN; DNA; GENOTYPE; HETEROCHROMATIN; HUMANS; LAMIN TYPE A; LAMINS; MICE; MICE, TRANSGENIC; MUTATION; NUCLEAR PROTEINS; PROGERIA; PROTEIN PRECURSORS; SEQUENCE DELETION;

EID: 77954176613     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.05.032     Document Type: Article

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