Metabolic stability of superoxide and hydroxyl radical adducts of a cyclic nitrone toward rat liver microsomes and cytosol: A stopped-flow ESR spectroscopy study

Free Radical Biology and Medicine

Volumn 49, Issue 3, 2010, Pages 437-446

  Bézière, Nicolas ^a   Frapart, Yves ^a   Rockenbauer, Antal ^b   Boucher, Jean Luc ^a   Mansuy, Daniel ^a   Peyrot, Fabienne ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b CHEMICAL RESEARCH CENTER   (Hungary)

Author keywords

Cyclic nitrones; Cytochromes P450; EPR spectroscopy; ESR spectroscopy; Hydroxyl radical; Spin trapping; Superoxide

Indexed keywords

ASCORBIC ACID; CYTOCHROME P450; GLUTATHIONE; HEMOPROTEIN; HORSERADISH PEROXIDASE; HYDROPEROXIDE; HYDROXYL RADICAL; METHEMOGLOBIN; NITRONE; SUPEROXIDE; 5-TERT-BUTOXYCARBONYL 5-METHYL-1-PYRROLINE N-OXIDE; AMINE OXIDE; HYDROGEN PEROXIDE; NITROGEN OXIDE; NITRONES; SPIN LABELING;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOTRANSFORMATION; CELL KINETICS; CHEMICAL REACTION; COMPUTER PROGRAM; CONTROLLED STUDY; CYTOSOL; ELECTRON SPIN RESONANCE; HALF LIFE TIME; LIVER MICROSOME; MALE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; RAT; RELIABILITY; SIMULATION; ANIMAL; CHEMISTRY; METABOLISM; PROCEDURES; SPIN LABELING; SPRAGUE DAWLEY RAT;

ANIMALS; ASCORBIC ACID; CYCLIC N-OXIDES; CYTOSOL; ELECTRON SPIN RESONANCE SPECTROSCOPY; HALF-LIFE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; MALE; METHEMOGLOBIN; MICROSOMES, LIVER; NITROGEN OXIDES; RATS; RATS, SPRAGUE-DAWLEY; SPIN LABELS; SUPEROXIDES;

ARMORACIA RUSTICANA; RATTUS;

EID: 77954143678     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.04.035     Document Type: Article

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