메뉴 건너뛰기




Volumn , Issue , 2010, Pages 436-444

Value of Animal Models for Predicting CNS Therapeutic Action

Author keywords

Biomarkers; Clinical outcome; Constructs; Drug discovery; Homology; Imaging; Pharmacogenetics; Pharmacological isomorphism; Phenotype; Translational research; Validity

Indexed keywords


EID: 77954118049     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-08-045396-5.00021-X     Document Type: Chapter
Times cited : (9)

References (32)
  • 1
    • 85069167035 scopus 로고    scopus 로고
    • Brain Imaging
    • Psychopharmacology (Berl) 2005, 180:581-788. Brain Imaging.
    • (2005) Psychopharmacology (Berl) , vol.180 , pp. 581-788
  • 2
    • 33646683808 scopus 로고    scopus 로고
    • Functions of frontostriatal systems in cognition: Comparative neuropsychopharmacological studies in rats, monkeys and humans
    • Chudasama Y., Robbins T.W. Functions of frontostriatal systems in cognition: Comparative neuropsychopharmacological studies in rats, monkeys and humans. Biological Psychology 2006, 73:19-38.
    • (2006) Biological Psychology , vol.73 , pp. 19-38
    • Chudasama, Y.1    Robbins, T.W.2
  • 3
    • 85069195566 scopus 로고    scopus 로고
    • CNS Drug Discovery and Development: Challenges and Opportunities
    • Neuropsychopharmacology 2009, 34:1-243. CNS Drug Discovery and Development: Challenges and Opportunities.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 1-243
  • 4
    • 26044460006 scopus 로고    scopus 로고
    • Model organisms: The ascent of mouse: Advances in modelling human depression and anxiety
    • Cryan J.F., Holmes A. Model organisms: The ascent of mouse: Advances in modelling human depression and anxiety. Nature Reviews Drug Discovery 2005, 4:775-790.
    • (2005) Nature Reviews Drug Discovery , vol.4 , pp. 775-790
    • Cryan, J.F.1    Holmes, A.2
  • 5
    • 0002577727 scopus 로고
    • Animal models of psychiatric disorders
    • Raven Press, New York, F.E. Bloom, D.J. Kupfer (Eds.)
    • Geyer M.A., Markou A. Animal models of psychiatric disorders. Psychopharmacology, the Fourth Generation of Progress 1995, 787-798. Raven Press, New York. F.E. Bloom, D.J. Kupfer (Eds.).
    • (1995) Psychopharmacology, the Fourth Generation of Progress , pp. 787-798
    • Geyer, M.A.1    Markou, A.2
  • 6
    • 0038823525 scopus 로고    scopus 로고
    • The endophenotype concept in psychiatry: Etymology and strategic intentions
    • Gottesman T.D., Gould The endophenotype concept in psychiatry: Etymology and strategic intentions. American Journal of Psychiatry 2003, 160:636-645.
    • (2003) American Journal of Psychiatry , vol.160 , pp. 636-645
    • Gottesman, T.D.1    Gould2
  • 7
    • 47249105964 scopus 로고    scopus 로고
    • Institute of Medicine Forum on Drug Discovery, Development, and Translation
    • Neuropsychopharmacology 2008, 33:2047-2092. Institute of Medicine Forum on Drug Discovery, Development, and Translation.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2047-2092
  • 8
    • 23244451582 scopus 로고    scopus 로고
    • Biomarkers and surrogate markers: An FDA perspective
    • Katz R. Biomarkers and surrogate markers: An FDA perspective. NeuroRx 2004, 1:189-195.
    • (2004) NeuroRx , vol.1 , pp. 189-195
    • Katz, R.1
  • 9
    • 7244236943 scopus 로고    scopus 로고
    • FDA: Evidentiary standards for drug development and approval
    • Katz R. FDA: Evidentiary standards for drug development and approval. NeuroRx 2004, 1:307-316.
    • (2004) NeuroRx , vol.1 , pp. 307-316
    • Katz, R.1
  • 11
    • 33748171121 scopus 로고    scopus 로고
    • Animal models of depression in drug discovery: A historical perspective
    • McArthur R., Borsini F. Animal models of depression in drug discovery: A historical perspective. Pharmacology Biochemistry and Behavior 2006, 84:436-452.
    • (2006) Pharmacology Biochemistry and Behavior , vol.84 , pp. 436-452
    • McArthur, R.1    Borsini, F.2
  • 15
    • 50249189084 scopus 로고    scopus 로고
    • Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: Association of TREK1 and treatment resistance in the STAR[*]D study
    • Perlis R.H., Moorjani P., Fagerness J., et al. Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: Association of TREK1 and treatment resistance in the STAR[*]D study. Neuropsychopharmacology 2008, 33:2810-2819.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2810-2819
    • Perlis, R.H.1    Moorjani, P.2    Fagerness, J.3
  • 16
    • 0031744291 scopus 로고    scopus 로고
    • Homology in behavioural pharmacology: An approach to animal models of human cognition
    • Robbins T.W. Homology in behavioural pharmacology: An approach to animal models of human cognition. Behavioural Pharmacology 1998, 9:509-519.
    • (1998) Behavioural Pharmacology , vol.9 , pp. 509-519
    • Robbins, T.W.1
  • 17
    • 0032886820 scopus 로고    scopus 로고
    • Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains
    • Rogers D.C., Jones D.N., Nelson P.R., Jones C.M., Quilter C.A., Robinson T.L., Hagan J.J. Use of SHIRPA and discriminant analysis to characterise marked differences in the behavioural phenotype of six inbred mouse strains. Behavioural Brain Research 1999, 105:207-217.
    • (1999) Behavioural Brain Research , vol.105 , pp. 207-217
    • Rogers, D.C.1    Jones, D.N.2    Nelson, P.R.3    Jones, C.M.4    Quilter, C.A.5    Robinson, T.L.6    Hagan, J.J.7
  • 19
    • 85069190832 scopus 로고    scopus 로고
    • A guide to drug discovery. An on-going series from Nature Reviews Drug Discovery. 2003-2008
    • A guide to drug discovery. An on-going series from Nature Reviews Drug Discovery. 2003-2008. http://www.nature.com/nrd/series/drugdiscovery/index.html.
  • 20
    • 85069155468 scopus 로고    scopus 로고
    • A comprehensive bibliography of preclinical and clinical CANTAB applications
    • A comprehensive bibliography of preclinical and clinical CANTAB applications. http://www.cantab.com/science/bibliography.asp.
  • 21
    • 85069197695 scopus 로고    scopus 로고
    • A Research Agenda for DSM-V, 2002
    • A Research Agenda for DSM-V, 2002. http://www.appi.org/book.cfm?id=2292.
  • 22
    • 85069199099 scopus 로고    scopus 로고
    • Code of Federal regulations (Title 21). Good Laboratory Practice for nonclinical laboratory studies
    • Code of Federal regulations (Title 21). Good Laboratory Practice for nonclinical laboratory studies. http://www.nal.usda.gov/awic/legislat/21cfr97.htm.
  • 23
    • 85069179166 scopus 로고    scopus 로고
    • Deconstructing Psychosis. 2007
    • Deconstructing Psychosis. 2007. http://www.appi.org/book.cfm?id=2653.
  • 24
    • 85069207950 scopus 로고    scopus 로고
    • European Consensus-Platform for Alternatives to Animal Experiments
    • European Consensus-Platform for Alternatives to Animal Experiments. http://www.emea.europa.eu/pdfs/human/swp/072895en.pdf.
  • 25
    • 85069225551 scopus 로고    scopus 로고
    • European Medicines Agency. Replacement of animal studies by in vitro models (1997)
    • European Medicines Agency. Replacement of animal studies by in vitro models (1997). http://www.ecopa.eu/.
  • 26
    • 85069214499 scopus 로고    scopus 로고
    • Guidance for industry. Animal models - essential elements to address efficacy under the animal rule (Draft 2009)
    • Guidance for industry. Animal models - essential elements to address efficacy under the animal rule (Draft 2009). http://www.fda.gov/cder/guidance/8324dft.pdf.
  • 27
    • 85069229354 scopus 로고    scopus 로고
    • Guidance for industry. Content and format of investigational new drug applications (INDs) for Phase 1 studies of drugs, including well-characterized, therapeutic, biotechnology-derived products. (1995)
    • Guidance for industry. Content and format of investigational new drug applications (INDs) for Phase 1 studies of drugs, including well-characterized, therapeutic, biotechnology-derived products. (1995). http://www.fda.gov/cder/guidance/phase1.pdf.
  • 28
    • 85069220148 scopus 로고    scopus 로고
    • Guidance for industry, investigators, and reviewers - Exploratory IND studies. (2006)
    • Guidance for industry, investigators, and reviewers - Exploratory IND studies. (2006). http://www.fda.gov/cder/guidance/7086fnl.pdf.
  • 29
    • 85069218977 scopus 로고    scopus 로고
    • Innovation or stagnation: Challenge and opportunity on the critical path to new medical products. 2004
    • Innovation or stagnation: Challenge and opportunity on the critical path to new medical products. 2004. http://www.fda.gov/oc/initiatives/criticalpath/whitepaper.html.
  • 30
    • 85069200813 scopus 로고    scopus 로고
    • Inspections and Standards of the UK Medicines and Healthcare Products Regulatory Agency
    • Inspections and Standards of the UK Medicines and Healthcare Products Regulatory Agency. http://www.mhra.gov.uk/Howweregulate/Medicines/Inspectionandstandards/GoodLaboratoryPractice/index.htm.
  • 31
    • 85069226049 scopus 로고    scopus 로고
    • NIH Roadmap for Medical Research
    • NIH Roadmap for Medical Research. http://nihroadmap.nih.gov/overview.asp.
  • 32
    • 85069194737 scopus 로고    scopus 로고
    • Present status of GlaxoSmithKline Phase III trial of rosiglitazone in an Alzheimer population stratified by APOE4 genotype
    • Present status of GlaxoSmithKline Phase III trial of rosiglitazone in an Alzheimer population stratified by APOE4 genotype. http://clinicaltrials.gov/ct2/show/NCT00550420?term=rosiglitazone+AND+alzheimer&rank=3.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.