Use of cross species genomic profiling identifies pathways and genes differentially regulated in prostate cancer cells treated with soy protein isolates or purified genistein

Cancer Genomics and Proteomics

Volumn 7, Issue 3, 2010, Pages 111-128

  Liss, Michael A ^a   Schlicht, Michael ^b   Degueme, Amy ^c   Hessner, Martin ^c   Datta, Milton W ^d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Beta catenin; Gene expression; Genistein; Metabolic pathway; Prostate cancer; Soy protein

Indexed keywords

GENISTEIN; SOYBEAN PROTEIN;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL GROWTH; CELL STRAIN LNCAP; CONTROLLED STUDY; CULTURE MEDIUM; DIETARY INTAKE; GENE CONTROL; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENOMICS; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROSTATE CANCER; RAT; ANIMAL; CELL PROLIFERATION; DATA MINING; DNA MICROARRAY; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; PROCEDURES; PROSTATIC NEOPLASMS; TUMOR CELL LINE;

RATTUS;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; DATA MINING; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENISTEIN; HUMANS; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROSTATIC NEOPLASMS; RATS; SOYBEAN PROTEINS;

EID: 77954100352     PISSN: 11096535     EISSN: 17906245     Source Type: Journal    
DOI: None     Document Type: Article

References (45)

1. Jemal A, Siegel R, Ward E et al.: Cancer statistics, 2009. CA Cancer J Clin 59: 225-249, 2009.
2. Nelson W, De Marzo AM and Isaacs WB: Prostate cancer. New England J Med 349: 366-381, 2003.
3. Hughes C, Murphy A, Martin C, Sheils O and O'Leary J: Molecular pathology of prostate cancer. J Clin Pathol 58(7): 673-684, 2005.
4. Mentor-Marcel R, Lamartiniere C, Eltoum I, Greenberg N and Elgavish A: Genistein in the diet reduces the incidence of poorly differentiated prostatic adenocarcinoma in transgenic mice (TRAMP). Cancer Res 61: 6777-6782, 2001. (Pubitemid 32896500)
5. Adlercreutz H, Fotsis T, Bannwart C, Wähälä K, Mäkelä T, Brunow G and Hase T: Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens, in urine of women on various habitual diets. J Steroid Biochem 25: 791-797, 1986. (Pubitemid 17227959)
6. Whittemore AS, Kolonel L, Wu A, John E, Gallagher R, Howe G, Burch J, Hankin J, Dreon D and West D: Prostate cancer in relation to diet, physical activity, and body size in blacks, whites, and Asians in the United States and Canada. J Natl Cancer Inst 87(9): 652-661, 1995.
7. Nelson WG: Prostate cancer prevention. J Nutrition 134(11): 3211S-3212, 2004.
8. Holzbeierlein JM, McIntosh J and Thrasher JB: The role of soy phytoestrogens in prostate cancer. Curr Opin Urol 15(1): 17-22, 2005. (Pubitemid 40105520)
9. Hedlund T et al: Soy isoflavonoid equal modulates the growth of benign and malignant prostatic epithelial cells in vitro. The Prostate 54: 68-78, 2003. (Pubitemid 36043838)
10. Pollard M and Wolter W: Prevention of spontaneous prostate-related cancer in Lobund-Wistar rats by a soy protein isolate/isoflavone diet. The Prostate 45: 101-105, 2000.
11. Pollard M, Wolter W and Sun L: Prevention of induced prostate-related cancer by soy protein isolate/isoflavone-supplemented diet in Lobund-Wistar rats. In Vivo 14(3): 389-392, 2000.
12. Pollard M and Luckert PH: Influence of isoflavones in soy protein isolates on development of induced prostate-related cancers in L-W rats. Nutr Cancer 28(1): 41-45, 1997.
13. Aronson WJ, Tymchuk N, Elashoff R, McBride WH, McLean C, Wang H and Heber D: Decreased growth of human prostate LNCaP tumors in SCID mice fed a low-fat, soy protein diet with isoflavones. Nutr Cancer 35: 130-136, 1999. (Pubitemid 30115123)
14. Hessner MJ, Wang X, Hulse K, Meyer L, Wu Y, Nye S, Guo SW and Ghosh S: Three color cDNA microarrays: quantitative assessment through the use of fluorescein-labeled probes. Nucleic Acids Res 31(4): e14, 2003.
15. Hessner MJ, Wang X, Khan S, Meyer L, Schlicht M, Tackes J, Datta MW, Jacob HJ and Ghosh S: Use of a three-color cDNA microarray platform to measure and control support-bound probe for improved data quality and reproducibility. Nucleic Acids Res 31(11): e60, 2003.
16. Schlicht M, Matysiak B, Brodzeller T, Wen XO, Liu H, Zhou G, R Dhir R, Hessner MJ, Tonellato P, Suckow M, Pollard M and Datta MW: Cross-species global and subset gene expression profiling identifies genes involved in prostate cancer response to selenium. BMC Genomics 5(1): 58, 2004.
17. Zhou G, Wen W, Liu H, Schlicht MJ, Hessner MJ, Tonellato PJ and Datta MW: B.E.A.R. GeneInfo: A tool for identifying gene-related biomedical publications through user modifiable queries. BMC Bioinformatics 5: 46, 2004.
18. Dahlquist KD, Salomonis N, Vranizan K, Lawlor SC and Conklin BR: GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways. Nat Genet 31(1): 19-20, 2002.
19. Doniger SW, Salomonis N, Dahlquist KD, Vranizan K, Lawlor SC and Conklin BR: MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data. Genome Biol 4(1): R7, 2003.
20. Chen WF, Huang MH, Tzang CH, Yang M and Wong MS: Inhibitory actions of genistein in human breast cancer (MCF-7) cells. Biochim Biophys Acta 1638(2): 187-196, 2003.
21. Casanova M, You L, Gaido KW, Archibeque-Engle S, Janszen DB and Heck HA: Developmental effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of genistein and daidzein with rat estrogen receptors alpha and beta in vitro. Toxicol Sci 51(2): 236-244, 1999. (Pubitemid 29496230)
22. Wang X, Clubbs EA and Bomser JA: Genistein modulates prostate epithelial cell proliferation via estrogen- and extracellular signal-regulated kinase-dependent pathways. J Nutr Biochem, 2005.
23. Takimoto CH, Glover K, Huang X, Hayes SA, Gallot L, Quinn M, Jovanovic BD, Shapiro A, Hernandez L, Goetz A, Llorens V, Lieberman R, Crowell JA, Poisson BA and Bergan RC: Phase I pharmacokinetic and pharmacodynamic analysis of unconjugated soy isoflavones administered to individuals with cancer. Cancer Epidemiol Biomarkers Prev 12(11 Pt 1): 1213-1221, 2003.
24. Yardy GW and Brewster SF: Wnt signalling and prostate cancer. Prostate Cancer Prostatic Dis 8(2): 119-126, 2005.
25. Voeller HJ, Truica CI and Gelmann EP: Beta-catenin mutations in human prostate cancer. Cancer Res 58(12): 2520-2523, 1998. (Pubitemid 28275418)
26. Huggins C and Hodges CV: Studies on prostatic cancer I: The effect of castration, estrogen and of androgen injection on serum phosphastases in metastatic carcinoma of the prostate. Cancer Res 1: 293, 1941.
27. Huggins C, Stevens RE and Hodges CV: Studies on prostatic cancer II: The effects of castration on advanced carcinoma of the prostate gland. Arch Surg 43: 209, 1941.
28. Small EJ: Hormonal therapy for metastatic prostate cancer. West J Med 160: 253, 1994.
29. Takahashi Y, Lavigne JA, Hursting SD, Chandramouli GV, Perkins SN, Barrett JC and Wang TT: Using DNA microarray analyses to elucidate the effects of genistein in androgen-responsive prostate cancer cells: identification of novel targets. Mol Carcinog 41(2): 108-119, 2004. (Pubitemid 39336760)
30. Bektic J, Berger AP and Pfeil K: Androgen receptor regulation by physiological concentrations of the isoflavonoid genistein in androgen-dependent LNCaP cells is mediated by estrogen receptor beta. Eur Urol 45: 245-251, 2004. (Pubitemid 38147834)
31. Dalais FS, Meliala A, Wattanapenpaiboon N, Frydenberg M, Suter DA, Thomson WK and Wahlqvist ML: Effects of a diet rich in phytoestrogens on prostate-specific antigen and sex hormones in men diagnosed with prostate cancer. Urology 64(3): 510-515, 2004. (Pubitemid 39200748)
32. Kazi A, Daniel KG and Smith DM: Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of genistein. Bio Pharm 66: 965-976, 2003. (Pubitemid 37083593)
33. Kumi-Diaka J, Sanderson NA and Hall A: The mediating role of caspase-3 protease in the intracellular mechanism of genistein-induced apoptosis in human prostatic carcinoma cell lines, DU145 and LNCaP. Biol Cell 92(8-9): 595-604, 2000. (Pubitemid 32366627)
34. WAF1, down-regulation of cyclin B, and induction of apoptosis in prostate cancer cells. Nutr Cancer 32: 123-131, 1998.
35. Li Y, Che M, Bhagat S, Ellis KL, Kucuk O, Doerge DR, Abrams J, Cher ML and Sarkar FH: Regulation of gene expression and inhibition of experimental prostate cancer bone metastasis by dietary genistein. Neoplasia 6(4): 354-363, 2004.
36. Peterson TG, Barnes S and Kim H: Genistein may inhibit the growth of human mammary epithelial (HME) cells by augmenting transforming growth factor beta (TGFbeta)) signaling. Am J Clin Nutr 68: 1527S-1528S, 1998.
37. Zhu H, Mazor M, Kawano Y, Walker MM, Leung HY and Armstrong K et al: Analysis of Wnt gene expression in prostate cancer: mutual inhibition by WNT11 and the androgen receptor. Cancer Res 64: 7918-7926, 2004.
38. Ohigashi, Mizuno R, Nakashima J, Marumo K and Murai M: Inhibition of Wnt signaling down-regulates Akt activity and induces chemosensitivity in PTEN-mutated prostate cancer cells. Prostate 62: 61-68, 2005.
39. Morin PJ: Beta-catenin signaling and cancer. Bioessays 21(12): 1021-1030, 1999.
40. Verras M and Sun Z: Roles and regulation of Wnt signaling and beta-catenin in prostate cancer. Cancer Lett 237(1): 22-32, 2006.
41. Kaminska B, Wesolowska A and Danilkiewicz M: TGF beta signalling and its role in tumour pathogenesis. Acta Biochim Pol 52(2): 329-337, 2005. (Pubitemid 41133768)
42. Sheehan GM, Kallakury BV, Sheehan CE, Fisher HA, Kaufman RP Jr and Ross JS: Smad4 protein expression correlates with grade, stage, and DNA ploidy in prostatic adenocarcinomas. Hum Pathol 36(11): 1204-1209, 2005.
43. Tokar EJ and Webber MM: Cholecalciferol (vitamin D(3)) inhibits growth and invasion by up-regulating nuclear receptors and 25-hydroxylase (CYP27A1) in human prostate cancer cells. Clin Exp Metastasis 22(3): 275-284, 2005.
44. Koh YS and Moore DD: Linkage of the nuclear hormone receptor genes NR1D2, THRB, and RARB: evidence for an ancient, large-scale duplication. Genomics 57(2): 289-292, 1999.
45. Xu RX, Lambert MH, Wisely BB, Warren EN, Weinert EE, Waitt GM, Williams JD, Collins JL, Moore LB, Willson TM and Moore JT: A structural basis for constitutive activity in the human CAR/RXRalpha heterodimer. Mol Cell 16(6): 919-928, 2004. (Pubitemid 40018402)