Development and characterisation of freeze-dried liposomes containing two anti-asthma drugs

Micro and Nano Letters

Volumn 5, Issue 3, 2010, Pages 184-188

  Elhissi, A M A ^a   Islam, M A ^b   Arafat, B ^a   Taylor, M ^a   Ahmed, W ^b  

^a UNIVERSITY OF CENTRAL LANCASHIRE   (United Kingdom)

^b UNIVERSITY OF CENTRAL LANCASHIRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHARACTERISATION; CRYOPROTECTANTS; LASER DOPPLER VELOCIMETRY; PHOSPHATIDYLCHOLINE; PULMONARY DELIVERY; SALBUTAMOL; SIZE ANALYSIS; SULPHATES; UNILAMELLAR LIPOSOMES;

DOPPLER EFFECT; LIPOSOMES; LOW TEMPERATURE DRYING; PHOTON CORRELATION SPECTROSCOPY; SUGAR (SUCROSE); ZETA POTENTIAL;

PHOSPHOLIPIDS;

BECLOMETASONE DIPROPIONATE; CHOLESTEROL; CRYOPROTECTIVE AGENT; DRUG CARRIER; LIPOSOME; PHOSPHATIDYLCHOLINE; SALBUTAMOL SULFATE; SUCROSE; TREHALOSE;

ARTICLE; CRYOPROTECTION; DRUG DELIVERY SYSTEM; DRUG DEVELOPMENT; DRUG FORMULATION; FREEZE DRYING; LASER DOPPLER FLOWMETRY; PHOTON CORRELATION SPECTROSCOPY; REHYDRATION; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

EID: 77954052555     PISSN: None     EISSN: 17500443     Source Type: Journal    
DOI: 10.1049/mnl.2010.0032     Document Type: Article

References (36)

1. Maurer, N., Fenske, D.B., and Cullis, P.R.: ' Developments in liposomal drug delivery systems ', Exp. Opin. Biol. Ther., 2001, 1, p. 923-947
2. Immordino, M.L., Dosio, F., and Cattel, L.: ' Stealth liposomes: review of the basic science, rationale, and clinical applications, existing and potential ', Int. J. Nanomed., 2006, 1, p. 297-315
3. Chen, C., Han, D., Cai, C., and Tang, X.: ' An overview of liposome lyophilization and its future potential ', J. Cont. Rel., 142, (3), p. 299-311
4. Kensil, C.R., and Dennis, E.A.: ' Alkaline hydrolysis of phospholipids in model membranes and the dependence of their state of aggregation ', Biochemistry, 1981, 20, p. 6079-6085
5. Grit, M., Smidt, J.H.D., Struijke, A., and Crommelin, D.J.A.: ' Hydrolysis of phosphotidylcholine in aqueous liposomes dispersions ', Int. J. Pharm., 1989, 50, p. 1-6
6. Hunt, C.A., and Tsang, S.: ' α-tocopherol retards autoxidation and prolongs the shelf-life of liposomes ', Int. J. Pharm., 1981, 8, p. 101-110
7. Gordon, R.E., Mayer, P.R., and Kildsig, D.O.: ' Lyophilization - a means of increasing shelf-life of phospholipid bilayer vesicles ', Drug Dev. Ind. Pharm., 1982, 8, p. 465-473
8. Crommelin, D.J.A., and van Bommel, E.M.G.: ' Stability of liposomes on storage: freeze dried, frozen or as an aqueous dispersion ', Pharm. Res., 1984, 4, p. 159-163
9. van Bommel, E.M.G., and Crommelin, D.J.A.: ' Stability of doxorubicin-liposomes on storage: as an aqueous dispersion, frozen or freeze-dried ', Int. J. Pharm., 1984, 22, p. 299-310
10. Crowe, L.M., Womersley, J.H., Crowe, D., Reid, D., Appel, L., and Rudolph, A.: ' Prevention of fusion and leakage in freeze-dried liposomes by carbohydrates ', Biochim. Biophys. Acta, 1986, 861, p. 131-140
11. Torchilin, V.P., and Weissig, V.: ' Liposomes ', 2nd (Oxford University Press, 2003)
12. Ivey, H., Roth, S., and Kattwinkel, J.: ' Nebulization of sonicated phospholipid for treatment of respiratory distress syndrome of infancy ', Paed. Res., 1977, 11, p. 573
13. Morimoto, Y., and Adachi, Y.: ' Pulmonary uptake of liposomal phosphatidylcholine upon intratracheal administration to rats ', Chem. Pharm. Bull., 1982, 30, p. 2248-2251
14. Taylor, K.M.G., Taylor, G., Kellaway, I.W., and Stevens, J.: ' The influence of liposomal encapsulation on sodium chromoglycate pharmacokinetics in man ', Pharm. Res., 1989, 6, p. 633-636
15. Barker, S.A., Taylor, K.M.G., and Short, M.D.: ' The deposition and clearance of liposome entrapped 99mTc-DTPA in the human respiratory tract ', Int. J. Pharm., 1994, 102, p. 159-165
16. Saari, S.M., Vidgren, M.T., Turjanmaa, V.M.H., Koskinen, M.O., and Nieminen, M.M.: ' Pulmonary distribution and clearance of two beclometasone liposome formulations in healthy volunteers ', Int. J. Pharm., 1999, 181, p. 1-9
17. Vidgren, M., Waldrep, J.C., and Arppe, J.: et al. ' A study of 99m-technetium-labelled beclomethasone dipropionate dilauroylphosphatidyl- choline liposome aerosols in normal volunteers ', Int. J. Pharm., 1995, 115, p. 209-216
18. Saari, S.M., Vidgren, M.T., Koskinen, M.O., Turjanmaa, V.M., Waldrep, J.C., and Nieminen, M.M.: ' Regional lung deposition and clearance of 99m Tc-labelled beclomethasone-DLPC liposomes in mild and severe asthma ', Chest, 1995, 113, p. 1573-1579
19. Konduri, K.S., Nandedkar, S., and Düzgüne, N.: et al. ' Efficacy of liposomal budesonide in experimental asthma ', J. Allergy Clin. Immunol., 2003, 111, p. 321-327
20. Konduri, K.S., Nandedkar, S., Rickaby, D.A., Düzgüne, N., and Gangadharam, P.R.J.: ' The use of sterically stabilized liposomes to treat asthma ', Methods Enzymol., 2005, 391, p. 413-427
21. Farr, S.J., Kellaway, I.W., Parry-Jones, D., and Woolfrey, S.G.: ' 99m-Technetium as a marker of liposomal deposition and clearance in the human lung ', Int. J. Pharm., 1985, 26, p. 303-316
22. Elhissi, A.M.A., and Taylor, K.M.G.: ' Delivery of liposomes generated from proliposomes using air-jet, ultrasonic, and vibrating-mesh nebulisers ', J. Drug Deliv. Sci. Technol., 2005, 15, p. 261-265
23. Elhissi, A.M.A., Karnam, K.K., Danesh, M.R., Gill, H.S., and Taylor, K.M.G.: ' Formulations generated from ethanol-based proliposomes for delivery via medical nebulizers ', J. Pharm. Pharmacol., 2006, 58, p. 887-894
24. Elhissi, A.M.A., Faizi, M., Naji, W.F., Gill, H.S., and Taylor, K.M.G.: ' Physical stability and aerosol properties of liposomes delivered using an air-jet nebulizer and a novel micropump device with large mesh apertures ', Int. J. Pharm., 2007, 334, p. 62-70
25. Taylor, K.M.G., Taylor, G., Kellaway, I.W., and Stevens, J.: ' The stability of liposomes to nebulisation ', Int. J. Pharm., 1990, 58, p. 57-61
26. Bridges, P.A., and Taylor, K.M.G.: ' Nebulisers for the generation of liposomal aerosols ', Int. J. Pharm., 1998, 173, p. 117-125
27. Bridges, P.A., and Taylor, K.M.: ' The effects of freeze-drying on the stability of liposomes to jet nebulization ', J. Pharm. Pharmacol., 2001, 53, p. 393-398
28. Darwis, Y., and Kellaway, I.W.: ' Nebulization of rehydrated freeze-dried beclometasone dipropionate liposomes ', Int. J. Pharm., 2001, 215, p. 113-121
29. Elhissi, A.M.A., O'Neill, M.A.A., Roberts, S.A., and Taylor, K.M.G.: ' A calorimetric study of dimyristoylphosphatidylcholine phase transitions and steroid-liposome interactions for liposomes prepared by thin film and proliposome methods ', Int. J. Pharm., 2006, 320, p. 124-130
30. Stewart, J.C.M.: ' Colorimetric determination of phospholipids with ammonium ferrothiocyanate ', Anal. Biochem., 1980, 104, p. 10-14
31. Bangham, A.D., Standish, M.M., and Watkins, J.C.: ' Diffusion of univalent ions across the lamellae of swollen phospholipids ', J. Mol. Biol., 1965, 13, p. 238-252
32. Mälkki, L., and Tammilehto, S.: ' Decomposition of salbutamol in aqueous solutions. I. The effect of pH, temperature and drug concentration ', Int. J. Pharm., 1990, 63, p. 17-22
33. Kirby, C., and Gregoriadis, G.: ' Dehydration-rehydration vesicles: a simple method for high yield drug entrapment in liposomes ', Nature Biotechnol., 1984, 2, p. 979-984
34. Mugabe, C., Azghani, A.O., and Omri, A.: ' Preparation and characterization of dehydrated-rehydrated vesicles loaded with aminoglycosides and macrolide antibiotics ', Int. J. Pharm., 2006, 307, p. 244-250
35. Vincourt, V., Nguyen, L., Chaumeil, J.C., and Dumortier, G.: ' Freeze-drying of ATP entrapped in cationic, low lipid liposomes ', Cryobiology, 60, (3), p. 262-270 0011-2240
36. Elhissi, A.M.A.: ' Proliposome formulations for delivery via medical nebulisers ', 2005, PhD, University of London, School of Pharmacy