Innate immune cells: Gatekeepers of endometriotic lesions growth and vascularization

Journal of Endometriosis

Volumn 2, Issue 2, 2010, Pages 55-62

  Capobianco, Annalisa ^a   Cottone, Lucia ^a   Monno, Antonella ^a   Ferrari, Stefano ^a   Panina Bordignon, Paola ^b   Manfredi, Angelo A ^a   Rovere Querini, Patrizia ^a  

^a VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^b BioXell SpA   (Italy)

Author keywords

Angiogenesis; Macrophages; Peritoneal lesions

Indexed keywords

ANGIOGENESIS; DISEASE COURSE; ENDOMETRIOSIS; FEMALE; HUMAN; IMMUNOCOMPETENT CELL; INNATE IMMUNITY; MACROPHAGE ACTIVATION; NONHUMAN; PATHOGENESIS; REVIEW; VASCULARIZATION;

EID: 77953999139     PISSN: 20359969     EISSN: 2036282X     Source Type: Journal    
DOI: 10.1177/228402651000200202     Document Type: Review

References (63)

1. Lebovic DI, Mueller MD, Taylor RN. Immunobiology of endometriosis. Fertil Steril 2001; 75: 1-10.
2. Giudice LC, Kao LC. Endometriosis. Lancet 2004; 364: 1789-99.
3. Berkley KJ, Rapkin AJ, Papka RE. The pains of endometriosis. Science 2005; 308: 1587-9.
4. Bulun SE. Endometriosis. N Engl J Med 2009; 360: 268-79.
5. Sampson J. Peritoneal endometriosis due to menstrual dissemination of endometrial tissue into the peritoneal cavity. Am J Obstet Gynecol 1927; 14: 422-69.
6. D'Hooghe TM, Debrock S. Endometriosis, retrograde menstruation and peritoneal inflammation in women and in baboons. Hum Reprod Update 2002; 8: 84-8.
7. Lucidi RS, Witz CA, Chrisco M, Binkley PA, Shain SA, Schenken RS. A novel in vitro model of the early endometriotic lesion demonstrates that attachment of endometrial cells to mesothelial cells is dependent on the source of endometrial cells. Fertil Steril 2005; 84: 16-21.
8. Nair AS, Nair HB, Lucidi RS, et al. Modeling the early endometriotic lesion: mesothelium-endometrial cell co-culture increases endometrial invasion and alters mesothelial and endometrial gene transcription. Fertil Steril 2008; 90: 1487-95.
9. Dunselman GA, Groothuis PG. Etiology of endometriosis: hypotheses and facts. Gynecol Obstet Invest 2004; 57: 42-3.
10. Becker CM, D'Amato RJ. Angiogenesis and antiangiogenic therapy in endometriosis. Microvasc Res 2007; 74: 121-30.
11. Girling JE, Rogers PA. Regulation of endometrial vascular remodeling: role of the vascular endothelial growth factor family and the angiopoietin-TIE signalling system. Reproduction 2009; 138: 883-93.
12. Rogers PA, Donoghue JF, Walter LM, Girling JE. Endometrial angiogenesis, vascular maturation, and lymphangiogenesis. Reprod Sci 2009; 16: 147-51.
13. Bokor A, Debrock S, Drijkoningen M, Goossens W, Fulop V, D'Hooghe T. Quantity and quality of retrograde menstruation: a case control study. Reprod Biol Endocrinol 2009; 7: 123.
14. van Amerongen MJ, Harmsen MC, van Rooijen N, Petersen AH, van Luyn MJ. Macrophage depletion impairs wound healing and increases left ventricular remodeling after myocardial injury in mice. Am J Pathol 2007; 170: 818-29.
15. Martinez FO, Sica A, Mantovani A, Locati M. Macrophage activation and polarization. Front Biosci 2008; 13: 453-61.
16. Goren I, Allmann N, Yogev N, et al. A transgenic mouse model of inducible macrophage depletion: effects of diphtheria toxin-driven lysozyme M-specific cell lineage ablation on wound inflammatory, angiogenic, and contractive processes. Am J Pathol 2009; 175: 132-47.
17. Mirza R, DiPietro LA, Koh TJ. Selective and specific macrophage ablation is detrimental to wound healing in mice. Am J Pathol 2009; 175: 2454-62.
18. Allavena P, Sica A, Solinas G, Porta C, Mantovani A. The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages. Crit Rev Oncol Hematol 2008; 66: 1-9.
19. Pollard JW. Macrophages define the invasive microenvironment in breast cancer. J Leukoc Biol 2008; 84: 623-30.
20. Bocci G, Fasciani A, Orlandi P, di Paolo A, Del Tacca M, R D. Vascular endothelial growth factor-A (VEGF-A) single nucleotide polymorphisms and endometriosis: still a controversial issue. Journal of Endometriosis 2009; 1: 94-101.
21. Campana L, Bosurgi L, Rovere-Querini P. HMGB1: a two-headed signal regulating tumor progression and immunity. Curr Opin Immunol 2008; 20: 518-23.
22. Campana L, Bosurgi L, Bianchi ME, Manfredi AA, Rovere-Querini P. Requirement of HMGB1 for stromal cell-derived factor-1/CXCL12-dependent migration of macrophages and dendritic cells. J Leukoc Biol 2009; 86: 609-15.
23. Lolmede K, Campana L, Vezzoli M, et al. Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1-and MMP-9-dependent pathways. J Leukoc Biol 2009; 85: 779-87.
24. Martinez FO, Helming L, Gordon S. Alternative activation of macrophages: an immunologic functional perspective. Annu Rev Immunol 2009; 27: 451-83.
25. Solinas G, Germano G, Mantovani A, Allavena P. Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation. J Leukoc Biol 2009; 86: 1065-73.
26. Qian B, Deng Y, Im JH, et al. A distinct macrophage population mediates metastatic breast cancer cell extravasation, establishment and growth. PLoS One 2009; 4: e6562.
27. De Palma M, Naldini L. Tie2-expressing monocytes (TEMs): novel targets and vehicles of anticancer therapy? Biochim Biophys Acta 2009; 1796: 5-10.
28. Gordon S. The macrophage: past, present and future. Eur J Immunol 2007; 37 (Suppl 1): S9-17.
29. Ferwerda B, McCall MB, Alonso S, et al. TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans. Proc Natl Acad Sci U S A 2007; 104: 16645-50.
30. Ferwerda B, McCall MB, Verheijen K, et al. Functional consequences of toll-like receptor 4 polymorphisms. Mol Med 2008; 14: 346-52.
31. Wu MH, Shoji Y, Wu MC, et al. Suppression of matrix metalloproteinase-9 by prostaglandin E(2) in peritoneal macrophage is associated with severity of endometriosis. Am J Pathol 2005; 167: 1061-9.
32. Petraglia F, Musacchio C, Luisi S, De Leo V. Hormone-dependent gynaecological disorders: a pathophysiological perspective for appropriate treatment. Best Pract Res Clin Obstet Gynaecol 2008; 22: 235-49.
33. Florio V, Pinzauti S, Altomare A, Luisi S, Litta P, Petraglia F. Expression and role of peptides, proteins and growth factors in the pathogenesis of endometriosis. Journal of Endometriosis 2009; 1: 79-93.
34. Zhang C, Maeda N, Izumiya C, et al. Killer immunoglobulin-like receptor and human leukocyte antigen expression as immunodiagnostic parameters for pelvic endometriosis. Am J Reprod Immunol 2006; 55: 106-14.
35. Lawson C, Al-Akoum M, Maheux R, Akoum A. Increased expression of interleukin-1 receptor type 1 in active endometriotic lesions. Reproduction 2007; 133: 265-74.
36. Minici F, Tiberi F, Tropea A, et al. Paracrine regulation of endometriotic tissue. Gynecol Endocrinol 2007; 23: 574-80.
37. Herrmann Lavoie C, Fraser D, Therriault MJ, Akoum A. Interleukin-1 stimulates macrophage migration inhibitory factor secretion in ectopic endometrial cells of women with endometriosis. Am J Reprod Immunol 2007; 58: 505-13. (Pubitemid 350091187)
38. Lousse JC, Van Langendonckt A, Gonzalez-Ramos R, Defrere S, Renkin E, Donnez J. Increased activation of nuclear factor-kappa B (NF-kappaB) in isolated peritoneal macrophages of patients with endometriosis. Fertil Steril 2008; 90: 217-20. (Pubitemid 351885195)
39. Galleri L, Luisi S, Rotondi M, et al. Low serum and peritoneal fluid concentration of interferon-gamma-induced protein-10 (CXCL10) in women with endometriosis. Fertil Steril 2009; 91: 331-4.
40. Timmer AM, Nizet V. IKKbeta/NF-kappaB and the miscreant macrophage. J Exp Med 2008; 205: 1255-9.
41. Hagemann T, Lawrence T, McNeish I, et al. "Re-educating" tumor-associated macrophages by targeting NF-kappaB. J Exp Med 2008; 205: 1261-8.
42. Gonzalez-Ramos R, Van Langendonckt A, Defrere S, et al. Agents blocking the nuclear factor-kappaB pathway are effective inhibitors of endometriosis in an in vivo experimental model. Gynecol Obstet Invest 2008; 65: 174-86. (Pubitemid 351562920)
43. Lousse JC, Defrere S, Gonzalez-Ramos R, Van Langendonckt A, Colette S, Donnez J. Involvement of iron, nuclear factor-kappa B (NF-kappa B) and prostaglandins in the pathogenesis of peritoneal endometriosis-associated inflammation: A review. Journal of Endometriosis 2009; 1: 19-29.
44. Palumbo R, Galvez BG, Pusterla T, et al. Cells migrating to sites of tissue damage in response to the danger signal HMGB1 require NF-kappaB activation. J Cell Biol 2007; 179: 33-40. (Pubitemid 47606681)
45. Wu MH, Chen KF, Lin SC, Lgu CW, Tsai SJ. Aberrant expression of leptin in human endometriotic stromal cells is induced by elevated levels of hypoxia inducible factor-1alpha. Am J Pathol 2007; 170: 590-8.
46. Becker CM, Rohwer N, Funakoshi T, et al. 2-methoxyestradiol inhibits hypoxia-inducible factor-1a and suppresses growth of lesions in a mouse model of endometriosis. Am J Pathol 2008; 172: 534-44. (Pubitemid 351282038)
47. Defrere S, Lousse JC, Gonzalez-Ramos R, Colette S, Donnez J, Van Langendonckt A. Potential involvement of iron in the pathogenesis of peritoneal endometriosis. Mol Hum Reprod 2008; 14: 377-85. (Pubitemid 351984797)
48. Lousse JC, Defrere S, Van Langendonckt A, et al. Iron storage is significantly increased in peritoneal macrophages of endometriosis patients and correlates with iron overload in peritoneal fluid. Fertil Steril 2009; 1: 1668-75.
49. Brunelli S, Rovere-Querini P. The immune system and the repair of skeletal muscle. Pharmacol Res 2008; 58: 117-21.
50. Chuang PC, Lin YJ, Wu MH, Wing LY, Shoji Y, Tsai SJ. Inhibition of CD36-dependent phagocytosis by prostaglandin E2 contributes to the development of endometriosis. Am J Pathol 2009; 176: 850-60.
51. Chuang PC, Wu MH, Shoji Y, Tsai SJ. Downregulation of CD36 results in reduced phagocytic ability of peritoneal macrophages of women with endometriosis. J Pathol 2009; 219: 232-41.
52. Schulze C, Munoz LE, Franz S, et al. Clearance deficiency - a potential link between infections and autoimmunity. Autoimmun Rev 2008; 8: 5-8.
53. Manfredi AA, Capobianco A, Bianchi ME, Rovere-Querini P. Regulation of dendritic- and T-cell fate by injury-associated endogenous signals. Crit Rev Immunol 2009; 29: 69-86.
54. Bacci M, Capobianco A, Monno A, et al. Macrophages are alternatively activated in patients with endometriosis and required for growth and vascularization of lesions in a mouse model of disease. Am J Pathol 2009; 175: 547-56.
55. Haber E, Danenberg HD, Koroukhov N, Ron-El R, Golomb G, Schachter M. Peritoneal macrophage depletion by liposomal bisphosphonate attenuates endometriosis in the rat model. Hum Reprod 2009; 24: 398-407.
56. Lin YJ, Lai MD, Lei HY, Wing LY. Neutrophils and macrophages promote angiogenesis in the early stage of endometriosis in a mouse model. Endocrinology 2006; 147: 1278-86.
57. Grummer R. Animal models in endometriosis research. Hum Reprod Update 2006; 12: 641-49.
58. Eggermont J, Donnez J, Casanas-Roux F, Scholtes H, Van Langendonckt A. Time course of pelvic endometriotic lesion revascularization in a nude mouse model. Fertil Steril 2005; 84: 492-9. (Pubitemid 41125275)
59. Verreck FA, de Boer T, Langenberg DM, van der Zanden L, Ottenhoff TH. Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-gamma-and CD40L-mediated costimulation. J Leukoc Biol 2006; 79: 285-93.
60. Allavena P, Chieppa M, Monti P, Piemonti L. From pattern recognition receptor to regulator of homeostasis: the double-faced macrophage mannose receptor. Crit Rev Immunol 2004; 24: 179-92.
61. Kristiansen M, Graversen JH, Jacobsen C, et al. Identification of the haemoglobin scavenger receptor. Nature 2001; 409: 198-201.
62. Borda JT, Alvarez X, Mohan M, et al. CD163, a marker of perivascular macrophages, is up-regulated by microglia in simian immunodeficiency virus encephalitis after haptoglobin-hemoglobin complex stimulation and is suggestive of breakdown of the blood-brain barrier. Am J Pathol 2008; 172: 725-37.
63. Harada T, Taniguchi F, Izawa M, et al. Apoptosis and endometriosis. Front Biosci 2007; 12: 3140-51.