Modulating the release kinetics of paclitaxel from membrane-covered stents using different loading strategies

Materials

Volumn 1, Issue 1, 2008, Pages 25-43

  Sydow Plum, Georg ^a,b   Haidar, Ziyad S ^a,b   Merhi, Yahye ^c   Tabrizian, Maryam ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c MONTREAL HEART INSTITUTE   (Canada)

Author keywords

Chitosan; Controlled drug release; Hyaluronic acid; Paclitaxel; Polyethylene oxide; Restenosis; Stent; Thrombogenecity

Indexed keywords

HYALURONIC ACID; POLYETHYLENE OXIDES; STENTS; TARGETED DRUG DELIVERY;

COVERED STENTS; DELIVERY SYSTEMS; HYDROPHOBIC DRUG; PLATELET ADHESION; POLYETHYLENE OXIDE (PEO); RELEASE KINETICS; RELEASE PATTERN; RELEASE PROFILES;

CONTROLLED DRUG DELIVERY;

EID: 77953993246     PISSN: None     EISSN: 19961944     Source Type: Journal    
DOI: 10.3390/ma1010025     Document Type: Article

References (34)

1. Dobesh, P.P.; Stacy, Z.A.; Ansara, A.J.; Enders, J.M. Drug-eluting stents: A mechanical and pharmacologic approach to coronary artery disease. Pharmacotherapy 2004, 24, 1554-1577.
2. Serruys, P.W.; Kutryk, M.J.; Ong, A.T. Coronary-artery stents. N. Engl. J. Med. 2006, 354, 483-495.
3. Wenaweser, P.; Daemen, J.; Zwahlen, M.; van Domburg, R.; Jüni, P.; Vaina, S.; Hellige, G.; Tsuchida, K.; Morger, C.; Boersma, E.; Kukreja, N.; Meier, B.; Serruys, P.W.; Windecker, S. Incidence and correlates of drug-eluting stent thrombosis in routine clinical practice. 4-year results from a large 2-institutional cohort study. J. Am. Coll. Cardiol. 2008, 52, 1134-1140.
4. Plum, G.; Tabrizian, M. Clinical Outcomes of Non Pharmaceutical Stent Coatings. In Fundamentals About Stents; Proceedings of the European Symposium of Vascular Biomaterials, 2005; pp. 83-102.
5. Menown, I.; Lowe, R.; Penn, I. Passive stent coatings in the drug-eluting era. J. Invasive Cardiol. 2005, 17, 222-228.
6. Presbitero, P.; Asioli, M. Drug-eluting stents do they make the difference? Minerva Cardioangiol. 2002, 50, 431-442.
7. Billesfeld, L.; Gerckens, U.; Muller, R.; Grube, E. Long-term evaluation of paclitaxel-coated stents for treatment of native coronary lesions. First results of both the clinical and angiographic 18 month follow-up of TAXUS I. Z. Kardiol. 2003, 92, 825-832.
8. Aoki, J.; Mintz, G.S.; Weissman, N.J.; Mandinov, L.; Grube, E.; Dawkins, K.D.; Ellis, S.G.; Greenberg, J.; Yu, A.; Mann, J.T.; Cannon, L.; Cambier, P.A.; Stone, G.W. Impact of mild or moderate renal insufficiency on the intravascular ultrasonic analysis of chronic vascular response to paclitaxel-eluting and bare-metal stents (from the TAXUS IV, V, and VI trials). Am. J. Cardiol. 2008, 102, 1009-16.
9. Mehvar, R. Recent trends in the use of polysaccharides for improved delivery of therapeutic agents: pharmacokinetic and pharmacodynamic perspectives. Curr. Pharm. Biotechnol. 2003, 4, 283-302.
10. Prabaharan, M.; Mano, J.F. Chitosan-based particles as controlled drug delivery systems. Drug Deliv. 2005, 12, 41-57.
11. Thierry, B.; Merhi, Y.; Silver, J.; Tabrizian, M. Biodegradable membrane-covered stent from chitosan-based polymers. J. Biomed. Mater. Res. A. 2005, 75, 556-566.
12. Chandy, T.; Sharma, C.P. Chitosan-as a biomaterial. Biomater. Artif. Cells Artif. Organs. 1990, 18, 1-24.
13. Budtova, T.; Belnikevich, N.; Kalyuzhnaya, L.; Alexeev, V.; Bronnikov, S.; Vesnebolotskkaya, S.; Zoolshoev, Z. Chitosan modified by poly(ethylene oxide): Film and mixture properties. J. Appl. Polym. Sci. 2002, 84, 1114-1122.
14. Neto, C.G.; Dantas, T.N.; Fonseca, J.L.; Pereira, M.R. Permeability studies in chitosan membranes. Effects of crosslinking and poly(ethylene oxide) addition. Carbohydr. Res. 2005, 340, 2630-2636.
15. Amiji, M. Permeability and blood compatibility properties of chitosan-poly(ethylene oxide) blend membranes for haemodialysis. Biomaterials 1995, 16, 593-599.
16. Amiji, M.; Park, K. Surface modification of polymeric biomaterials with poly(ethylene oxide), albumin, and heparin for reduced thrombogenicity. J. Biomater. Sci. Polym. Ed. 1993, 4, 217-234.
17. Thierry, B.; Winnik, F.M.; Merhi, Y.; Silver, J.; Tabrizian, M. Bioactive coatings of endovascular stents based on polyelectrolyte multilayers. Biomacromolecules 2003, 4, 1564-1571.
18. Thierry, B.; Kujawa, P.; Tkaczyk, C.; Winnik, F.M.; Bilodeau, L.; Tabrizian, M. Delivery platform for hydrophobic drugs: prodrug approach combined with self-assembled multilayers. J. Am. Chem. Soc. 2005, 127, 1626-1627.
19. Yang, Y.; Moussa, I. Percutaneous coronary intervention and drug-eluting stents. Can. Med. Ass. J. 2005, 172, 323-325.
20. Schneider, A.; Vodouhe, C.; Richert, L.; Francius, G.; Le Guen, E.; Schaaf, P.; Voegel, J.C.; Frisch, B.; Picart, C. Multifunctional polyelectrolyte multilayer films: Combining mechanical resistance, biodegradability, and bioactivity. Biomacromolecules 2007, 8, 139-145.
21. Verheye, S.; Markou, C.P.; Salame, M.Y.; Wan, B.; King, S.B.; Robinson, K.A.; Chronos, N.A.; Hanson, S.R. Reduced thrombus formation by hyaluronic acid coating of endovascular devices. Arterioscler. Thromb. Vasc. Biol. 2000, 20, 1168-1172.
22. Hahn, S.K.; Hoffman, A.S. Preparation and characterization of biocompatible polyelectrolyte complex multilayer of hyaluronic acid and poly-l-lysine. Int. J. Biol. Macromol. 2005, 37, 227-231.
23. Heublein, B.; Evagorou, E.G.; Rohde, R.; Ohse, S.; Meliss, R.R.; Barlach, S.; Haverich, A. Polymerized degradable hyaluronan--a platform for stent coating with inherent inhibitory effects on neointimal formation in a porcine coronary model. Int. J. Artif. Organs 2002, 25, 1166-1173.
24. Lu, H.; Hu, N. Loading behavior of (chitoan/hyaluronic acid)n layer-by-layer assembly films toward myoglobin: an electrochemical study. J. Phys. Chem. B 2006, 110, 23710-23718.
25. Deutsch, H.M.; Glinski, J.A.; Hernandez, M.; Haugwitz, R.D.; Narayanan, V.L.; Suffness, M.; Zalkow, M.L. Synthesis of congeners and prodrugs. 3. Water-soluble prodrugs of taxol with potent antitumor activity. J. Med. Chem. 1989, 32, 788-792.
26. Higuchi, T. Rate of release of medicaments from ointment bases containing drugs in suspension. J. Pharm. Sci. 1961, 50, 874-875.
27. Bienvenu, J.G.; Tanguay, J.F.; Chauvet, P.; Merhi, Y. Relationship between platelets and neutrophil adhesion and neointimal growth after repeated arterial wall injury induced by angioplasty in pigs. J. Vasc. Res. 2001, 38, 153-162.
28. Kastrati, A.; Mehilli, J.; Dirschinger, J.; Dotzer, F.; Schuhlen, H.; Neumann, F.J.; Fleckenstein, M.; Pfafferott, C.; Seyfarth, M.; Schomig, A. Intracoronary stenting and angiographic results: Strut thickness effect on restenosis outcome (ISAR-STEREO) trial. Circulation 2001, 103, 2816-2821.
29. Luo, Y.; Ziebell, M.R.; Prestwich, G.D. A hyaluronic acid-taxol antitumor bioconjugate targeted to cancer cells. Biomacromolecules 2000, 1, 208-218.
30. Siepmann, J.; Peppas, N.A. Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC). Adv. Drug Deliv. Rev. 2001, 48, 139-157.
31. Plum, G. Freisetzungsverhalten von unterschiedlich hydrophil/hydrophoben Modellsubstanzen aus Poly-(D,L-lactid)-und Poly-(D,L-lactid)-co-PEO-co-poly-(D,L-lactid)-Mikrosphären und pharmazeutische Anwendungen. Thesis, RWTH-Aachen, 2004.
32. Obara, K.; Ishihara, M.; Ozeki, Y.; Ishizuka, T.; Hayashi, T.; Nakamura, S.; Saito, Y.; Yura, H.; Matsui, T.; Hattori, H.; Takase, B.; Ishihara, M.; Kikuchi, M.; Maehara, T. Controlled release of paclitaxel from photocrosslinked chitosan hydrogels and its subsequent effect on subcutaneous tumor growth in mice. J. Contr. Release. 2005, 110, 79-89.
33. Siepmann, J.; Elkharraz, K.; Siepmann, F.; Klose, D. How autocatalysis accelerates drug release from PLGA-based microparticles: a quantitative treatment. Biomacromolecules 2005, 6, 2312-2319.
34. Amarnath, L.P.; Srinivas, A.; Ramamurthi, A. In vitro hemocompatibility testing of UV-modified hyaluronan hydrogels. Biomaterials 2006, 27, 1416-1424.