Synthesis and biological evaluation of oxazole derivatives as T-type calcium channel blockers

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 14, 2010, Pages 4219-4222

  Lee, Jie Eun ^a,b   Koh, Hun Yeong ^b   Seo, Seon Hee ^a   Baek, Yi Yeon ^a   Rhim, Hyewhon ^a   Cho, Yong Seo ^a   Choo, Hyunah ^a   Pae, Ae Nim ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Inha University   (South Korea)

Author keywords

1G Subtype; HTS assay; Neuropathic pain; Oxazole; T type calcium channel

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL T TYPE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.1; MIBEFRADIL; OXAZOLE DERIVATIVE;

AMINATION; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DRUG SCREENING; DRUG SYNTHESIS; INHIBITION KINETICS; SUBSTITUTION REACTION; SWERN OXIDATION;

CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, T-TYPE; DRUG EVALUATION, PRECLINICAL; OXAZOLES;

EID: 77953871878     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.05.030     Document Type: Article

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