Activation of the mitochondrial protein quality control system and actin cytoskeletal alterations in cells harbouring the MELAS mitochondrial DNA mutation

Journal of the Neurological Sciences

Volumn 295, Issue 1-2, 2010, Pages 46-52

  Felk, Sandra ^a   Ohrt, Susanne ^b   Kussmaul, Lothar ^a   Storch, Alexander ^b   Gillardon, Frank ^a  

^a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

2D DIGE; Actin cytoskeleton; Lon protease; MELAS; Mitochondria; Proteome

Indexed keywords

ACTIN BINDING PROTEIN; CYTOSKELETON PROTEIN; ENDOPEPTIDASE LA; HEAT SHOCK PROTEIN 60; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN;

ARTICLE; B LYMPHOCYTE; BLOOD SAMPLING; CELL LINE; CELL LYSATE; CELL STRESS; CONTROLLED STUDY; ENZYME ASSAY; GEL ELECTROPHORESIS; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; MELAS SYNDROME; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEOMICS; QUALITY CONTROL; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY CHAIN;

ACTINS; CYTOSKELETON; DNA, MITOCHONDRIAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HUMANS; LYMPHOCYTES; MASS SPECTROMETRY; MELAS SYNDROME; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIAL PROTEINS; MUTATION; PROTEOME;

EID: 77953869128     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2010.05.013     Document Type: Article

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