Hypotriglyceridemic effect of Morus alba L., Moraceae, leaves in hyperlipidemic rats;Efeito hipotrigliceridêmico de folhas de Morus alba L., Moraceae, em ratos hiperlipidêmicos

Revista Brasileira de Farmacognosia

Volumn 20, Issue 1, 2010, Pages 130-133

  Zeni, Ana Lúcia B ^a   Dall'Molin, Mauren ^a  

^a REGIONAL UNIVERSITY OF BLUMENAU   (Brazil)

Author keywords

Hyperlipidemic rats; Morus alba; Triglycerides

Indexed keywords

CHOLESTEROL; LIVER ENZYME; MULBERRY EXTRACT; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAZIL; CHOLESTEROL DIET; CONTROLLED STUDY; DRUG EFFECT; HYPERLIPIDEMIA; MORACEAE; MULBERRY; NONHUMAN; PLANT LEAF; RAT; TRADITIONAL MEDICINE; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 77953823888     PISSN: 0102695X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0102-695X2010000100025     Document Type: Article

References (32)

1. Austin MA 1989. Plasma triglyceride as a risk factor for coronary heart disease. Am J Epidemiol 129: 249-259.
2. Bainton D, Miller NE, Botton CH, Yarnell JWG, Suretman PM, Baker IA, Lewis B, Elwood PC 1992. Plasma triglycerides and high density lipoprotein cholesterol predictors of ischemic heart diseases in British man. Br Heart J 68: 60-66.
3. Burtis CA, Ashwood ER 2001. Tietz Textbook of Clinical Chemistry. Philadelphia: WB Saunders.
4. Cambien F, Jacquenson A, Richard JL, Warnet JM, Ducimetiere P, Claude JR 1986. Is the level of serum triglyceride a significant predictor of coronary death in ''normocholesterolemic'' subjects? The paris prospective study. Am J E pidemiol 124: 624-632.
5. Chan PT, Fong WP, Cheung YL, Huang Y, Ho WK, Chen ZY 1999. Jasmine green tea epicatechins are hypolipidemic in hamsters (Mesocricetus auratus) fed a high fat diet. J Nutr 129: 1094-1101.
6. Chen F, Nakashima N, Kimura M. 1995. Hypoglycemic activity and mechanism of extracts from mulberry leaves and cortex mori radices in streptozotocin induced diabetic mice. Yakugaku Zasshi 115: 476-482.
7. Chen, CC, Liu LK, Hsu JD, Huang HP, Yang MY, Wang CJ 2005. Mulberry extract inhibits the development of atherosclerosis in cholesterol-fed rabbits. Food Chem 91: 601-607.
8. Chevalier A 1996. The encyclopedia of medicinal plants. New York: DK Publishingp. 235.
9. Chobanian AV 1991. Single risk factor intervention may be inadequate to inhibit atherosclerosis progression when hypertension and hypercholesterolemic coexist. Hypertension 18: 130-131.
10. El-Bebshbishy HA, Singab ANB, Sinkkonen J, Pihlaja K 2006. Hypolipidemic and antioxidant effects of Morus alba L. (Egyptian mulberry) root bark fractions supplementation in cholesterol-fed rats. Life Sci 78: 2724-2733.
11. El-Hazmi MA, Warsy AS 2001. Evaluation of serum cholesterol and triglycerides levels in 1-6 year-old Saudi children. J Trop Pediatr 47: 181-185.
12. Friedman RB, Young DS 1997. Effects of Disease on Clinical Laboratory Tests. Washington: AACC Press.
13. Fukai T, Nomura T. 1998. Proof against 2'- hydroxy-3 prenylflavone-oxygen complex by laser desorption/ ionization time-of-flight mass spectrometry. Rapid Commun Mass Sp 12: 1945-1951.
14. Fukai T, Satoh K, Nomura T, Sakagami H. 2003. Antinephritis and radical scavenging activities of prenylflavonoids. Fitoterapia 74: 720-724.
15. Gerasopoulos D, Stavorulakis G. 1997. Quality characteristics of four mulberry (Morus sp) cultivars in the area of China, Greece. J Sci Food Agric 73: 261-264.
16. Hikino H, Mizuno T, Oshima Y, Konno C 1985. Validity of the oriental medicines. 80. Antidiabetes drugs. 4. Isolation and hypoglycemic activity of moran A, a glycoprotein of Morus alba root bark. Planta Med 51: 159-160.
17. Jin WY, Na MK, Na RB, Lee HY, Bae KH, Kang SS 2002. Antioxidant compounds from twig of Morus alba. Nat Prod Sci 8: 129-132.
18. Kaio D, Takashi K, Mitsuko M, Yumiko K, Yasuo F 2001. Studies on the constituints of the leaves of Morus alba L. Chem Pharm Bull Tokyo 49: 151-153.
19. Kannel WB, Castelli WP, Gordon T, McNamara PM 1971. Serum cholesterol, lipoproteins, and the risk of coronary heart disease. Ann Inter Med 74: 1-12.
20. Kim ES, Park SJ, Lee EJ, Kim BK, Huh H, Lee BJ 1999. Purification and characterization of Moran 20 K from Morus alba. Arch Pharmacol Res 22: 9-12.
21. Nomura T, Fukai T, Katayanagi M 1977. Oxidative ciclization of morusin with manganese dioxide. Heterocycles 6: 1847-1854.
22. Nomura T, Fukai T, Matsumoto, J. J 1980. Studies on the constituents of the cultivated mulberry tree. 6. Oxidative cyclization of morusin. Heteroc Chem 17:641-646.
23. Nomura T. Phenolic compounds of the mulberry tree and related plants. In: Herz W, Grisebach H, Kirby GW, Tamm CH 1988. Progress in the chemistry of organic natural products. vol. 53. Vienna: Springer, 87-201.
24. Quer PF 1995. Plantas medicinales. Barcelona: Labor.
25. Rosa COB, Costa NMB, Nunes RM, Leal PFG 1998. Efeito dos feijões (Phaseolus vulgaris L.) preto, carioquinha e vermelho na redução do colesterol sangüíneo de ratos hipercolesterolêmicos. Arch Latinoam Nutr 48: 306-310.
26. Sharma HM, Hanna A, Kauffman EM, Newman HA 1992. Inhibition of human low density lipoprotein oxidation in vitro by Maharishi Ayurveda herbal mixtures. Pharmacol Biochem Behav 43: 1175-1182.
27. Sharma R, Sharma A, Shono T, Takasugi M, Shirata A, Fujimura T, Machii H 2001. Mulberry moracins: scavengers of UV stress-generated free radicals. Biosci Biotechnol Biochem 65: 1402-1405.
28. Soares D, Marthendal G, Zimmerman MC, Zeni ALB 2005. Estudo dos níveis lipídicos em ratos após tratamento com infusão de algumas plantas medicinais de uso popular. Rev Bras Farm 86: 71-74.
29. Wang IK, Lin-Shiau SY, Chen PC, Lin JK 2000. Hypotrigliceridemic effect of Anka (a fermented rice product of Monascus sp) in rats. J Agric Food Chem 48: 3183-3189.
30. Yagi M, Kouno T, Aoyagi Y, Murai H 1976. The structure of maranoline, a piperidine alkaloid from Morus species. Nippon Nogei Kagaku Kaishi 50: 571-572.
31. Yamatake Y, Shibata M, Nagai M 1976. Pharmacological studies on root bark of mulberry tree (Morus alba L.). Jpn J Pharmacol 26: 461-469.
32. Yeh CW, Chen WJ, Chiang CT, Lin-Shiau SY, Lin JK 2003. Supression of fatty acid synthase in MCF-7 breast cancer cells by tea and tea polyphenols: A possible mechanism for their hypolipidemic effects. Pharmacogen J 3: 267-726.