Aldose reductase inhibition prevents lipopolysaccharide-induced glucose uptake and glucose transporter 3 expression in RAW264.7 macrophages

International Journal of Biochemistry and Cell Biology

Volumn 42, Issue 6, 2010, Pages 1039-1045

  Reddy, Aramati B M ^a   Srivastava, Satish K ^a   Ramana, Kota V ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Aldose reductase; CAMP; CREB; Glucose transporters; LPS; PKA

Indexed keywords

3 METHYLGLUCOSE; ALDEHYDE REDUCTASE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT MODULATOR; DNA; GLUCOSE; GLUCOSE TRANSPORTER 3; MESSENGER RNA; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; GLUCOSE TRANSPORT; INFLAMMATION; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; UPREGULATION;

ALDEHYDE REDUCTASE; ANIMALS; CELL LINE; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT MODULATOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; GLUCOSE; GLUCOSE TRANSPORTER TYPE 3; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; PHOSPHORYLATION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UP-REGULATION;

BACTERIA (MICROORGANISMS); MURINAE;

EID: 77953809886     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2010.03.014     Document Type: Article

References (44)

1. Ahmed N., Kansara M., Berridge M.V. Acute regulation of glucose transport in a monocyte-macrophage cell line: Glut-3 affinity for glucose is enhanced during the respiratory burst. Biochem J 1997, 327:369-375.
2. Barton K., Muthusamy N., Chanyangam M., Fischer C., Clendenin C., Leiden J.M. Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB. Nature 1996, 379:81-85.
3. Berk J.L., Hagen J.F., Beyer W.H., Gerber M.J. Hypoglycemia of shock. Ann Surg 1970, 171:400-408.
4. Cohen J. The immunopathogenesis of sepsis. Nature 2002, 420:885-891.
5. Crane R.K. Intestinal absorption of sugars. Physiol Rev 1960, 40:789-825.
6. Delghandi M.P., Johannessen M., Moens U. The cAMP signalling pathway activates CREB through PKA, p38 and MSK1 in NIH 3T3 cells. Cell Signal 2005, 17:1343-1351.
7. Ebeling P., Koistinen H.A., Koivisto V.A. Insulin-independent glucose transport regulates insulin sensitivity. FEBS Lett 1998, 436:301-303.
8. Ezeamuzie C.I., Taslim N. Reactive oxygen species mediate phorbol ester-stimulated cAMP response in human eosinophils. Eur J Pharmacol 2006, 543:174-180.
9. Fazia M.D., Servillo G., Sassone-Corsi P. Cyclic AMP signalling and cellular proliferation: regulation of CREB and CREM. FEBS Lett. 1997, 410:22-24.
10. Filkins J.P. Phase of glucose dyshomeostasis in endotoxicosis. Circ Shock 1978, 5:347-355.
11. Fischer K., Lees J., Newman L. Hypoglycemia in hospitalized patients: causes and outcomes. N Engl J Med 1986, 315:1245-1250.
12. Fu Y., Maianu L., Melbert B.R., Garvey W.T. Facilitative glucose transporter gene expression in human lymphocytes, monocytes, and macrophages: a role for GLUT isoforms 1, 3, and 5 in the immune response and foam cell formation. Blood Cells Mol Dis 2004, 32:182-190.
13. Fukuzumi M., Shinomiya H., Shimizu Y., Ohishi K., Utsumi S. Endotoxin-induced enhancement of glucose influx into murine peritoneal macrophages via GLUT1. Infect Immun 1996, 64:108-112.
14. Hinshaw L.B. The role of glucose in endotoxin shock. Circ Shock 1976, 3:1-10.
15. Hardy S., Shenk T. Adenoviral control regions activated by E1A and the cAMP response element bind to the same factor. Proc Natl Acad Sci USA 1998, 85:4171-4175.
16. Hayes M.R., Skibicka K.P., Bence K.K., Grill H.J. Dorsal hindbrain 5'-adenosine monophosphate-activated protein kinase as an intracellular mediator of energy balance. Endocrinology 2009, 150:2175-2182.
17. Hotamisligil G.S., Shargill N.S., Spiegelman B.M. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 1993, 259:87-91.
18. Kaneko M., Bucciarelli L., Hwang Y.C., Lee L., Yan S.F., Schmidt A.M., et al. Aldose reductase and AGE-RAGE pathways: key players in myocardial ischemic injury. Ann N Y Acad Sci 2005, 1043:702-709.
19. Karin M., Lin A. NF-κB at the crossroads of life and death. Nat Immunol 2002, 3:221-227.
20. Lang C.H., Dobrescu C. Gram-negative infective infection increases noninsulin-mediated glucose disposal. Endocrinology 1991, 128:645-653.
21. Lang C.H., Dobrescu C. Sepsis-induced increases in glucose uptake by macrophage-rich tissues persist during hypoglycemia. Metabolism 1991, 40:585-593.
22. Lang C.H., Bagby G.J., Spitzer J.J. Glucose kinetics and body temperature after lethal and nonlethal doses of endotoxin. Am J Physiol 1985, 248:R471-R478.
23. Liu L., Wang Y., Fan Y., Li C., Chang Z. IFN-γ activates cAMP/PKA/CREB signaling pathway in murine peritoneal macrophages. J Interferon Cytokine Res 2004, 24:334-342.
24. McGowan K.M., Police S., Winslow J.B., Pekala P.H. Tumor necrosis factor-alpha regulation of glucose transporter (GLUT1) mRNA turnover. Contribution of the 3prime-untranslated region of the Glut1 message. J Biol Chem 1997, 272:1331-1337.
25. Meszaros K., Lang C.H., Bagby G.J., Spitzer J.J. Contribution of different organs to increased glucose consumption after endotoxin. J Biol Chem 1987, 262:10965-10970.
26. Molina C.A., Foulkes N.S., Lalli E., Sassone-Corsi P. Inducibility and negative autoregulation of CREM: an alternative promoter directs the expression of ICER, an early response repressor. Cell 1993, 75:875-886.
27. Montminy M.R., Gonzalez G.A., Yamamoto K.K. Regulation of camp-inducible genes by CREB. Trends Neurosci 1990, 13:84-188.
28. Miller S.I., Ernst R.K., Bader M.W. LPS, TLR4 and infectious disease diversity. Nat Rev Microbiol 2005, 3:36-46.
29. Muthenna P., Suryanarayana P., Gunda S.K., Petrash J.M., Reddy G.B. Inhibition of aldose reductase by dietary antioxidant curcumin: mechanism of inhibition, specificity and significance. FEBS Lett 2009, 583:3637-3642.
30. Nathan C. Points of control in inflammation. Nature 2002, 420:846-852.
31. Oates P.J. Aldose reductase, still a compelling target for diabetic neuropathy. Curr Drug Targets 2008, 9:14-36.
32. Osawa Y., Lee H.T., Hirshman C.A., Xu D., Emala C.W. Lipopolysaccharide-induced sensitization of adenylyl cyclase activity in murine macrophages. Am J Physiol Cell Physiol 2006, 290:C143-C151.
33. Palsson-McDermott E.M., O'Neill L.A. Signal transduction by the lipopolysaccharide receptor. Toll-like receptor-4. Immunology 2004, 113:153-162.
34. Phillips T., Ferraz I., Bell S., Clegg P.D., Carter S.D., Mobasheri A. Differential regulation of the GLUT1 and GLUT3 glucose transporters by growth factors and pro-inflammatory cytokines in equine articular chondrocytes. Vet J 2005, 169:216-222.
35. Ramana K.V., Chandra D., Srivastava S., Bhatnagar A., Aggarwal B.B., Srivastava S.K. Aldose reductase mediates mitogenic signaling in vascular smooth muscle cells. J Biol Chem 2002, 30:32063-32070.
36. Ramana K.V., Fadl A.A., Tammali R., Reddy A.B., Chopra A.K., Srivastava S.K. Aldose reductase mediates the lipopolysaccharide-induced release of inflammatory mediators in RAW264.7 murine macrophages. J Biol Chem 2006, 281:33019-33029.
37. Ramana K.V., Srivastava S.K. Mediation of aldose reductase in lipopolysaccharide-induced inflammatory signals in mouse peritoneal macrophages. Cytokine 2006, 36:115-122.
38. Ramana K.V., Willis M.S., White M.D., Horton J.W., DiMaio J.M., Srivastava D., et al. Endotoxin-induced cardiomyopathy and systemic inflammation in mice is prevented by aldose reductase inhibition. Circulation 2006, 24:1838-1846.
39. Ramana K.V., Reddy A.B., Tammali R., Srivastava S.K. Aldose reductase mediates endotoxin-induced production of nitric oxide and cytotoxicity in murine macrophages. Free Radic Biol Med 2007, 15:1290-1302.
40. Ramana K.V., Srivastava S.K. Aldose reductase: a novel therapeutic target for inflammatory pathologies. Int J Biochem Cell Biol 2010, 42:17-20.
41. Reddy A.B., Srivastava S.K., Ramana K.V. Anti-inflammatory effect of aldose reductase inhibition in murine polymicrobial sepsis. Cytokine 2009, 48:170-176.
42. Ryu H., Lee J., Impey S., Ratan R.R., Ferrante R.J. Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mit. Proc Natl Acad Sci USA 2005, 102:13915-13920.
43. Schuster D.P., Brody S.L., Zhou Z., Bernstein M., Arch R., Link D., et al. Regulation of lipopolysaccharide-induced increases in neutrophil glucose uptake. Am J Physiol Lung Cell Mol Physiol 2007, 292:L845-L851.
44. Thomson D.M., Herway S.T., Fillmore N., Kim H., Brown J.D., Barrow J.R., et al. AMP-activated protein kinase phosphorylates transcription factors of the CREB family. J Appl Physiol 2008, 104:429-438.