Addition of dexmedetomidine to bupivacaine for greater palatine nerve block prolongs postoperative analgesia after cleft palate repair

European Journal of Anaesthesiology

Volumn 27, Issue 3, 2010, Pages 280-284

  Obayah, Gihan M ^a,b   Refaie, Amira ^a   Aboushanab, Ossama ^a   Ibraheem, Neamat ^a   Abdelazees, Mossad ^b  

^a Department of Anesthesia ^*  (United States)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Cleft palate; Dexmedetomidine; Palatine nerve block

Indexed keywords

ATROPINE; BUPIVACAINE; DEXMEDETOMIDINE; EPHEDRINE; FENTANYL; SEVOFLURANE;

ADJUVANT THERAPY; ANALGESIC ACTIVITY; ARTICLE; BRADYCARDIA; CHILD; CLEFT PALATE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG USE; FEMALE; GENERAL ANESTHESIA; HEART RATE; HEMODYNAMICS; HUMAN; HYPOTENSION; INFANT; MALE; NERVE BLOCK; PAIN ASSESSMENT; PALATINE TONSIL; PALATOPLASTY; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PERIOD; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL; SEDATION; SURGICAL TECHNIQUE; SYSTOLIC BLOOD PRESSURE;

BUPIVACAINE; CLEFT PALATE; DEXMEDETOMIDINE; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; INFANT; MALE; NERVE BLOCK; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PALATE, HARD; PROSPECTIVE STUDIES; TIME FACTORS;

EID: 77953794049     PISSN: 02650215     EISSN: 13652346     Source Type: Journal    
DOI: 10.1097/EJA.0b013e3283347c15     Document Type: Article

References (28)

1. Strong EB, Buckmiller LM. Management of the cleft palate. Facial Plast Surg Clin North Am 2001; 9:15-25.
2. Hatch DJ. Analgesia in the neonate. Br Med J (Clin Res Ed) 1987; 294:920.
3. Hager H, Marhofer P, Sitzwohl C, et al. Caudal clonidine prolongs analgesia from caudal S(+)-ketamine in children. Anesth Analg 2002; 94:1169-1172.
4. Eisenach JC, De Kock M, Klimscha W. alpha(2)-Adrenergic agonists for regional anesthesia: a clinical review of clonidine (1984-1995). Anesthesiology 1996; 85:655-674.
5. Casati A, Magistris L, Fanelli G, et al. Small-dose clonidine prolongs postoperative analgesia after sciatic-femoral nerve block with 0.75% ropivacaine for foot surgery. Anesth Analg 2000; 91:388-392.
6. El Saied AH, Steyn MP, Ansermino JM. Clonidine prolongs the effect of ropivacaine for axillary brachial plexus blockade. Can J Anaesth 2000; 47:962-967.
7. Eledjam JJ, Deschodt J, Viel EJ, et al. Brachial plexus block with bupivacaine: effects of added alpha-adrenergic agonists - comparison between clonidine and epinephrine. Can J Anaesth 1991; 38:870-875.
8. Culebras X, Van Gessel E, Hoffmeyer P, Gamulin Z. Clonidine combined with a long acting local anesthetic does not prolong postoperative analgesia after brachial plexus block but does induce hemodynamic changes. Anesth Analg 2001; 92:199-204.
9. Duma A, Urbanek B, Sitzwohl C, et al. Clonidine as an adjuvant to local anaesthetic axillary brachial plexus block: a randomized, controlled study. Br J Anaesth 2005; 94:112-116.
10. Gaumann D, Forster A, Griessen M, et al. Comparison between clonidine and epinephrine admixture to lidocaine in brachial plexus block. Anesth Analg 1992; 75:69-74.
11. Jaakola ML, Ali-Melkkila T, Kanto J, et al. Dexmedetomidine reduces intraocular pressure, intubation responses and anaesthetic requirements in patients undergoing ophthalmic surgery. Br J Anaesth 1992; 68:570-575.
12. Kanazi GE, Aouad MT, Jabbour-Khoury SI, et al. Effect of low-dose dexmedetomidine or clonidine on the characteristics of bupivacaine spinal block. Acta Anaesthesiol Scand 2006; 50:222-227.
13. Saadawy I, Boker A, Elshahawy MA, et al. Effect of dexmedetomidine on the characteristics of bupivacaine in a caudal block in pediatrics. Acta Anaesthesiol Scand 2009; 53:251-256.
14. Memis D, Turan A, Karamanlioglu B, et al. Adding dexmedetomidine to lidocaine for intravenous regional anesthesia. Anesth Analg 2004; 98:835-840.
15. Brummett CM, Norat MA, Palmisano JM, Lydic R. Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat. Anesthesiology 2008; 109:502-511.
16. Malamed SF, Trieger N. Intraoral maxillary nerve block: an anatomical and clinical study. Anesth Prog 1983; 30:44-48.
17. Merkel SI, Voepel-Lewis T, Shayevitz JR, Malviya S. The FLACC: a behavioral scale for scoring postoperative pain in young children. Pediatr Nurs 1997; 23:293-297.
18. Doyle E, Harper I, Morton NS. Patient-controlled analgesia with low dose background infusions after lower abdominal surgery in children. Br J Anaesth 1993; 71:818-822. (Pubitemid 23356625)
19. Iskandar H, Benard A, Ruel-Raymond J, et al. The analgesic effect of interscalene block using clonidine as an analgesic for shoulder arthroscopy. Anesth Analg 2003; 96:260-262.
20. Gaumann DM, Brunet PC, Jirounek P. Hyperpolarizing afterpotentials in C fibers and local anesthetic effects of clonidine and lidocaine. Pharmacology 1994; 48:21-29.
21. Gordon TR, Kocsis JD, Waxman SG. Electrogenic pump (Na+/K(+)- ATPase) activity in rat optic nerve. Neuroscience 1990; 37:829-837.
22. Dalle C, Schneider M, Clergue F, et al. Inhibition of the I(h) current in isolated peripheral nerve: a novel mode of peripheral antinociception? Muscle Nerve 2001; 24:254-261.
23. Coban YK, Senoglu N, Oksuz H. Effects of preoperative local ropivacaine infiltration on postoperative pain scores in infants and small children undergoing elective cleft palate repair. J Craniofac Surg 2008; 19:1221-1224.
24. Starke K, Wagner J, Schumann HJ. Adrenergic neuron blockade by clonidine: comparison with guanethidine and local anesthetics. Arch Int Pharmacodyn Ther 1972; 195:291-308.
25. Bhananker SM, Azavedo LF, Splinter WM. Addition of morphine to local anesthetic infiltration does not improve analgesia after pediatric dental extractions. Paediatr Anaesth 2008; 18:140-144.
26. Demiraran Y, Ilce Z, Kocaman B, Bozkurt P. Does tramadol wound infiltration offer an advantage over bupivacaine for postoperative analgesia in children following herniotomy? Paediatr Anaesth 2006; 16:1047-1050.
27. Jonnavithula N, Durga P, Kulkarni DK, Ramachandran G. Bilateral intra-oral, infra-orbital nerve block for postoperative analgesia following cleft lip repair in paediatric patients: comparison of bupivacaine vs bupivacaine-pethidine combination. Anaesthesia 2007; 62:581-585.
28. Singelyn FJ, Gouverneur JM, Robert A. A minimum dose of clonidine added to mepivacaine prolongs the duration of anesthesia and analgesia after axillary brachial plexus block. Anesth Analg 1996; 83:1046-1050.