Addition of morphine to local anesthetic infiltration does not improve analgesia after pediatric dental extractions

Paediatric Anaesthesia

Volumn 18, Issue 2, 2008, Pages 140-144

  Bhananker, Sanjay M ^a,b   Azavedo, Lawrence F ^a   Splinter, William M ^a  

^a CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Dental extraction analgesia; Pediatric anesthesia; Peripheral opiate receptor

Indexed keywords

ADRENALIN; FENTANYL; HALOTHANE; KETOROLAC; LIDOCAINE; MIDAZOLAM; MIVACURIUM; MORPHINE; NITROUS OXIDE; OPIATE RECEPTOR; PARACETAMOL; PROPOFOL; SEVOFLURANE;

ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; LOCAL ANESTHESIA; MALE; PAIN ASSESSMENT; PEDIATRIC ANESTHESIA; POSTOPERATIVE PAIN; PREMEDICATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; STATISTICAL ANALYSIS; TOOTH EXTRACTION; VOMITING;

ANESTHETICS, LOCAL; CHILD; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; DRUG SYNERGISM; FEMALE; HUMANS; LIDOCAINE; MALE; MORPHINE; PAIN, POSTOPERATIVE; TOOTH EXTRACTION;

EID: 37749051432     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/j.1460-9592.2007.02399.x     Document Type: Article

References (16)

1. Primosch RE, Nichols DL, Courts FJ. Comparison of preoperative ibuprofen, acetaminophen, and placebo administration on the parental report of postextraction pain in children. Pediatr Dent 1995 17 : 187 191.
2. Kokki H, Hendolin H, Maunuksela EL et al. Ibuprofen in the treatment of postoperative pain in small children. A randomized double-blind-placebo controlled parallel group study. Acta Anesthesiol Scand 1994 38 : 467 472.
3. Coggeshall RE, Zhou S, Carlton SM. Opioid receptors on peripheral sensory axons. Brain Res 1997 764 : 126 132.
4. Maekawa K, Minami M, Yabuuchi K et al. In situ hybridization study of mu- and kappa-opioid receptor mRNAs in the rat spinal cord and dorsal root ganglia. Neurosci Lett 1994 168 : 97 100.
5. Hassan AH, Ableitner A, Stein C et al. Inflammation of the rat paw enhances axonal transport of opioid receptors in the sciatic nerve and increases their density in the inflamed tissue. Neuroscience 1993 55 : 185 195.
6. Likar R, Sittl R, Gragger K et al. Peripheral morphine analgesia in dental surgery. Pain 1998 76 : 145 150.
7. Aldrete JA, Kroulik D. A postanesthetic recovery score. Anesth Analg 1970 49 : 924 934.
8. Stein C, Comisel K, Haimerl E et al. Analgesic effect of intraarticular morphine after arthroscopic knee surgery. N Engl J Med 1991 325 : 1123 1126.
9. Stein C, Pfluger M, Yassouridis A et al. No tolerance to peripheral morphine analgesia in presence of opioid expression in inflamed synovia. J Clin Invest 1996 98 : 793 799.
10. Rosseland LA, Stubhaug A, Grevbo F et al. Effective pain relief from intra-articular saline with or without morphine 2 mg in patients with moderate-to-severe pain after knee arthroscopy: a randomized, double-blind controlled clinical study. Acta Anesthesiol Scand 2003 47 : 732 738.
11. Kardash K, Schools A, Concepcion M. Effects of brachial plexus fentanyl on supraclavicular block. A randomized, double-blind study. Reg Anesth 1995 20 : 311 315.
12. Rosenstock C, Andersen G, Antonsen K et al. Analgesic effect of incisional morphine following inguinal herniotomy under spinal anesthesia. Reg Anesth 1996 21 : 93 98.
13. Picard PR, Tramer MR, McQuay HJ et al. Analgesic efficacy of peripheral opioids (all except intra-articular): a qualitative systematic review of randomised controlled trials. Pain 1997 72 : 309 318.
14. Rosseland LA. No evidence for analgesic effect of intra-articular morphine after knee arthroscopy: a qualitative systematic review. Reg Anesth Pain Med 2005 30 : 83 98.
15. Kaczmarzyk T, Stypulkowska J. Assessment of the effectiveness of peripheral administration of morphine with local articaine anaesthesia for surgery in inflamed oral and maxillofacial tissues. Pain 2005 115 : 348 354.
16. Likar R, Schafer M, Trampitsch E et al. Topical application of local anesthetics and opioids after elective tooth extraction. Schmerz 2005 19 : 195 198, 200.