Differential expression of neuropeptide Y Y1 receptors during pulpal inflammation

International Endodontic Journal

Volumn 43, Issue 6, 2010, Pages 492-498

  Rethnam, Sivakami ^a   Raju, B ^a   Fristad, I ^a   Berggreen, E ^a   Heyeraas, K J ^a  

^a UNIVERSITY OF BERGEN   (Norway)

Author keywords

Dental pulp; Immune cells; Inflammation; NPY; Sympathetic nerves

Indexed keywords

NEUROPEPTIDE Y RECEPTOR; NEUROPEPTIDE Y Y1 RECEPTOR; NEUROPEPTIDE Y-Y1 RECEPTOR;

ANALYSIS OF VARIANCE; ANIMAL; ARTICLE; BLOOD VESSEL; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; MALE; MANDIBLE; METABOLISM; MOLAR TOOTH; PATHOLOGY; PULPITIS; RAT; SPRAGUE DAWLEY RAT; TIME; TOOTH PULP; TRIGEMINUS GANGLION; VASCULARIZATION;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD VESSELS; DENTAL PULP; GENE EXPRESSION REGULATION; MALE; MANDIBLE; MOLAR; PULPITIS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROPEPTIDE Y; TIME FACTORS; TRIGEMINAL GANGLION;

EID: 77953791306     PISSN: 01432885     EISSN: 13652591     Source Type: Journal    
DOI: 10.1111/j.1365-2591.2010.01704.x     Document Type: Article

References (32)

1. Bedoui S, Kawamura N, Straub RH, Pabst R, Yamamura T, von Horsten S. Relevance of neuropeptide Y for the neuroimmune crosstalk. Journal of Neuroimmunology 2003a, 134:1-11.
2. Bedoui S, Miyake S, Lin Y. Neuropeptide Y (NPY) suppresses experimental autoimmune encephalomyelitis: NPY1 receptor-specific inhibition of autoreactive Th1 responses in vivo. Journal of Immunology 2003b, 171:3451-8.
3. Blomqvist AG, Herzog H. Y-receptor subtypes--how many more? Trends in Neurosciences 1997, 20:294-8.
4. Brumovsky PR, Shi TJ, Matsuda H, Kopp J, Villar MJ, Hökfelt T. NPY Y1 receptors are present in axonal processes of DRG neurons. Experimental Neurology 2002, 174:1-10.
5. El Karim IA, Lamey PJ, Linden GJ, Lundy FT. Neuropeptide Y Y1 receptor in human dental pulp cells of noncarious and carious teeth. International Endodontic Journal 2008, 41:850-5.
6. Elenkov IJ, Wilder RL, Chrousos GP, Vizi ES. The sympathetic nerve - an integrative interface between two supersystems: the brain and the immune system. Pharmacological Reviews 2000, 52:595-638.
7. Fristad I, Heyeraas KJ, Kvinnsland IH. Neuropeptide Y expression in the trigeminal ganglion and mandibular division of the trigeminal nerve after inferior alveolar nerve axotomy in young rats. Experimental Neurology 1996, 142:276-86.
8. Gibbs JL, Hargreaves KM. Neuropeptide Y Y1 receptor effects on pulpal nociceptors. Journal of Dental Research 2008, 87:948-52.
9. Gibbs J, Flores CM, Hargreaves KM. Neuropeptide Y inhibits capsaicin-sensitive nociceptors via a Y1-receptor-mediated mechanism. Neuroscience 2004, 125:703-9.
10. Gibbs J, Flores CM, Hargreaves KM. Attenuation of capsaicin-evoked mechanical allodynia by peripheral neuropeptide Y Y1 receptors. Pain 2006, 124:167-74.
11. Haug SR, Heyeraas KJ. Effects of sympathectomy on experimentally induced pulpal inflammation and periapical lesions in rats. Neuroscience 2003, 120:827-36.
12. Haug SR, Heyeraas KJ. Immunoglobulin producing cells in the rat dental pulp after unilateral sympathectomy. Neuroscience 2005, 136:571-7.
13. Haug SR, Heyeraas KJ. Modulation of dental inflammation by the sympathetic nervous system. Journal of Dental Research 2006, 85:488-95.
14. Haug SR, Berggreen E, Heyeraas KJ. The effect of unilateral sympathectomy and cavity preparation on peptidergic nerves and immune cells in rat dental pulp. Experimental Neurology 2001, 169:182-90.
15. Haug SR, Brudvik P, Fristad I, Heyeraas KJ. Sympathectomy causes increased root resorption after orthodontic tooth movement in rats: immunohistochemical study. Cell and Tissue Research 2003, 313:167-75.
16. Heyeraas KJ, Kvinnsland I, Byers MR, Jacobsen EB. Nerve fibers immunoreactive to protein gene product 9.5, calcitonin gene-related peptide, substance P, and neuropeptide Y in the dental pulp, periodontal ligament, and gingiva in cats. Acta Odontologica Scandinavica 1993, 51:207-21.
17. Hokfelt T, Broberger C, Zhang X. Neuropeptide Y: some viewpoints on a multifaceted peptide in the normal and diseased nervous system. Brain Research Reviews 1998, 26:154-66.
18. Hokfelt T, Brumovsky P, Shi T, Pedrazzini T, Villar M. NPY and pain as seen from the histochemical side. Peptides 2007, 28:365-72.
19. Kim SK, Ang L, Hsu YY, Dorscher-Kim J, Kim S. Antagonistic effect of D-myo-inositol-1,2,6-trisphosphate (PP56) on neuropeptide Y-induced vasoconstriction in the feline dental pulp. Archives of Oral Biology 1996, 41:791-8.
20. Larhammar D. Structural diversity of receptors for neuropeptide Y, peptide YY and pancreatic polypeptide. Regulatory Peptides 1996, 65:165-74.
21. Mahinda TB, Taylor BK. Intrathecal neuropeptide Y inhibits behavioral and cardiovascular responses to noxious inflammatory stimuli in awake rats. Physiology and Behavior 2004, 80:703-11.
22. Malmstrom RE. Neuropeptide Y Y1 receptor mechanisms in sympathetic vascular control. Acta Physiologica Scandinavica Supplementum 1997, 636:1-55.
23. Mark MA, Colvin LA, Duggan AW. Spontaneous release of immunoreactive neuropeptide Y from the central terminals of large diameter primary afferents of rats with peripheral nerve injury. Neuroscience 1998, 83:581-9.
24. Matsuda H, Brumovsky PR, Kopp J, Pedrazzini T, Hokfelt T. Distribution of neuropeptide Y Y1 receptors in rodent peripheral tissues. Journal of Comparative Neurology 2002, 449:390-404.
25. Naveilhan P, Hassani H, Lucas G. Reduced antinociception and plasma extravasation in mice lacking a neuropeptide Y receptor. Nature 2001, 409:513-17.
26. Tada T. The immune system as a supersystem. Annual Review of Immunology 1997, 15:1-13.
27. Tatemoto K. Neuropeptide Y: complete amino acid sequence of the brain peptide. Proceedings of the National Academy of Sciences of the United States of America 1982, 79:5485-9.
28. Wahlestedt C, Hakanson R, Vaz CA, Zukowska-Grojec Z. Norepinephrine and neuropeptide Y: vasoconstrictor cooperation in vivo and in vitro. American Journal of Physiology 1990, 258:R736-42.
29. Wakisaka S, Kajander KC, Bennett GJ. Increased neuropeptide Y (NPY)-like immunoreactivity in rat sensory neurons following peripheral axotomy. Neuroscience Letters 1991, 124:200-3.
30. Wheway J, Mackay CR, Newton RA. A fundamental bimodal role for neuropeptide Y1 receptor in the immune system. Journal of Experimental Medicine 2005, 202:1527-38.
31. Wheway J, Herzog H, Mackay F. The Y1 receptor for NPY: a key modulator of the adaptive immune system. Peptides 2007, 28:453-8.
32. Zukowska Z, Grant DS, Lee EW. Neuropeptide Y: a novel mechanism for ischemic angiogenesis. Trends in Cardiovascular Medicine 2003, 13:86-92.