Role of UDP-Glucuronosyltransferase Isoforms in 13-cis Retinoic Acid Metabolism in Humans

Drug Metabolism and Disposition

Volumn 38, Issue 7, 2010, Pages 1211-1217

  Rowbotham, Sophie E ^a   Illingworth, Nicola A ^a   Daly, Ann K ^a   Veal, Gareth J ^a   Boddy, Alan V ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

4 OXOISOTRETINOIN; CARBOXYLIC ACID; GLUCURONIDE; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A3; GLUCURONOSYLTRANSFERASE 1A7; GLUCURONOSYLTRANSFERASE 1A8; GLUCURONOSYLTRANSFERASE 1A9; ISOTRETINOIN; 4-OXORETINOIC ACID; ISOENZYME; RETINOIC ACID;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CONJUGATION; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; GLUCURONIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTESTINE; LIVER MICROSOME; MICROSOME; PRIORITY JOURNAL; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; ENZYME SPECIFICITY; ENZYMOLOGY; IN VITRO STUDY; KINETICS; METABOLISM;

GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HUMANS; INTESTINES; ISOENZYMES; ISOTRETINOIN; KINETICS; MICROSOMES; MICROSOMES, LIVER; SUBSTRATE SPECIFICITY; TRETINOIN; IN VITRO TECHNIQUES;

EID: 77953773633     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.109.031625     Document Type: Article

References (16)

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