Effect of quercetin supplement on major biochemical parameters in sera of rats fed high fat and high cholesterol diet

Journal of Veterinary Clinics

Volumn 26, Issue 5, 2009, Pages 413-418

  Hwang, Eui Kyung ^a  

^a Sangji University   (South Korea)

Author keywords

Cholesterol; HDL C; LDL C; Quercetin; Rat

Indexed keywords

RATTUS;

EID: 77953755971     PISSN: 1598298X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Aherne SA, O'Brien NM. Protection by the flavonoids myricetin, quercetin, and rutin against hydrogen peroxide-induced DNA damage in Caco-2 and Hep G2 cells. Nutr Cancer 1999; 34: 160-166.
2. Amresh G, Zeashan H, Gupta RJ, Kant R, Rao CV, Singh PN. Gastroprotective effects of ethanolic extract from Cissampelos pareira in experimental animals. J Nat Med 2007; 61: 323-328.
3. Basarkar PW, Nath N. Hypocholesterolemic and hypolipidemic activity of quercetin-a vitamin P-like compound in rats. Indian J Med Res 1983; 77: 122-126.
4. Basile A, Sorbo S, Sorbo S, Giodano S, Ricciardi L, Ferrara S, Montesano D, Cobianchi RC, Vuotto ML, Ferrara L. Antibacterial and allelopathic activity of extract from Castanea sativa leaves. Fitoterapia 2000; 71: S110-S116.
5. Bok SH, Park SY, Park YB, Lee MK, Jeon SM, Jeong TS, Choi MS. Quercetin dihydrate and gallate supplements lower plasma and hepatic lipids and change activities of hepatic antioxidant enzymes in high cholesterol-fed rats. Int J Vitam Nutr Res 2002; 72: 161-169.
6. Choi EJ, Chee KM, Lee BH. Anti- and prooxidant effects of quercetin administration in rats. Eur J Pharmacol 2003; 482: 281-285.
7. Cook NC, Samman S. Flavonoids - Chemistry, metabolism, cardioprotective effects, and dietary sources. J Nutr Biochem 1996; 7: 66-76.
8. Crespy V, Morand C, Besson C, Manach C, Demigne C, Remesy C. Quercetin, but not its glycosides, is absorbed from the rat stomach. J Agric Food Chem 2002; 50: 618-621.
9. Crespy V, Morand C, Manach C, Besson C, Demigne C, Remesy C. Part of quercetin absorbed in the small intestine is conjugated and further secreted in the intestinal lumen. Am J Physiol Gastrointest Liver Physiol 1999; 277: 120-126.
10. Dunnett CW. A multiple comparison procedure for comparing several treatments with a control. Am Stat Assoc J 1955; 50: 1096-1121.
11. Erlund I. Review of the flavonoids quercetin, hesperetin, and naringenin. Dietary sources, bioactivities, bioavailability, and epidemiology. Nutr Res 2004; 24: 851-874.
12. Exon JH, Magnuson BA, South EH, Hendrix K. Dietary quercetin, immune functions and colonic carcinogenesis in rats. Immunopharmacol Immunotoxicol 1998; 20: 173-190.
13. Formica JV, Regelson W. Review of the biology of quercetin and related bioflavonoids. Fd Chem Toxic 1995; 33: 1061-1080.
14. Friewald WT, Levy RI, Fredrickson DS. Estimation of concentration of low density lipoprotein cholesterol without use of the preparation of ultracentrifuge. Clin Chem 1972; 28: 499-502.
15. Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. High density lipoprotein as a protective factor against coronary heart disease. Am J Med 1977; 62: 707-714.
16. Gläβer G, Graefe EU, Struck F, Veit M, Gebhardt R. Comparison of antioxidative capacities and inhibitory effects on cholesterol biosynthesis of quercetin and potential metabolites. Phyto-medicine 2002; 9: 33-40.
17. Haglund O, Luostarinen R, Wallin R, Wibell L, Saldeen T. The effects of fish oil on triglyceride, cholesterol, fibrinogen and malondialdehyde in humans supplemented with vitamin. Eur J Nutr 1991; 121: 165-169.
18. Havsteen BH. The biochemistry and medical significance of the flavonoids. Phamacol Therap 2002; 96: 67-202.
19. Hertog MGL, Hollman PCH, Katan MB. Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands. J Agric Chem 1992; 40: 2379-2383.
20. Hirono I, Ueno I, Hosaka S, Takanashi H, Matsushima T, Sugimura T, Natori S. Carcinogenicity examination of quercetin and rutin in ACI rats. Cancer Letters 1981; 13: 15-21.
21. Holmes DL. Clinical laboratory animal medicine. Ames: Iowa State University Press 1984: 110-111.
22. Hou L, Zhou B, Yang L, Liu ZL. Inhibition of human low density lipoprotein oxidation by flavonols and their glycosides. Chem Phys Lipids 2004; 129: 209-219.
23. Igarashi K, Ohmuma M. Effects of isohamnetin, rhamnetin, and quercetin on the concentrations of cholesterol and lipo-peroxide in the serum and liver and on the blood and liver antioxidative enzyme activities of rats. Biosci Biotech Biochem 1995; 59: 595-601.
24. Janbaz KH, Saeed SA, Gilani AH. Studies on the protective effects of caffeic acid and quercetin on chemical-induced hepatotoxicity in rodents. Phytomedicine 2004; 11: 424-430.
25. Kannel WB, Castelli WP, Gordon T, McNamara PM. Serum cholesterol, lipoproteins, and the risk of coronary heart disease. Ann Intern Med 1971; 74: 1-12.
26. Lee E, Choi EJ, Cheong H, Kim YR, Ryu SY, Kim KM. Antiallergic actions of the leaves of Castanea crenata and isolation of an active component responsible for the inhibition of mast cell degranulation. Arch Pharm Res 1999; 22: 320-323.
27. Lee JH, Kang YH, Kang JS. Free radical scavenging of flavonoids and their effects on erythrocyte Na leak, platelet aggregation and TBARS production. Nutr Sci 2002; 5: 197-202.
28. Manach C, Morand C, Demigné C, Texier O, Régérat F, Rémésy C. Bioavailability of rutin and quercetin in rats. FEBS Letters 1997; 409: 12-16.
29. Manach C, Morand C, Texier O, Favier M-L, Agullo G, Demigne C, Régérat F, Rémésy C. Quercetin metabolites in plasma of rats fed diets containing rutin or quercetin. J Nutr 1995; 125: 1911-1922.
30. Manach C, Scalbert A, Morand C, Rémésy C, Jiménez L. Polyphenols: food and bioavailability. Am J Clin Nutr 2004; 79: 727-747.
31. Mattson FH, Erickson BA, Kligman AM. Effect of dietary cholesterol on serum cholesterol in man. Am J Clin Nutr 1972; 25: 589-594.
32. Mitruka BM, Rawnsley HM. Clinical biochemical and hematological reference values in normal experimental animals and normal humans. 2nd ed New York: Masson Publishing USA, Inc 1981: 57-166.
33. Mott GE, Jackson EM, McMahan CA, McGill HC Jr. Dietary cholesterol and type of fat differentially affect cholesterol metabolism and atherosclerosis in baboons. J Nutr 1992; 122: 1397-1406.
34. Packard CJ, McKinney L, Carr K, Shepherd J. Cholesterol feeding increases low density lipoprotein synthesis. J Clin Invest 1983; 72: 45-51.
35. Peterson J, Dwyer J. Flavonoids: Dietary occurrence and biochemical activity. Nutr Res 1998; 18: 1995-2018.
36. Rao CV, Vijayakumar M. Effect of quercetin, flavonoids and α-tocopherol, an antioxidant vitamin on experimental reflux oesophagitis in rats. Eur J Pharmacol 2008;589:233-238.
37. Rathi AB, Nath N, Chari SN. Action of vitamin P like compounds on lysosomal status in hypercholesterolemic rats. Acta Vitaminol Enzymol 1883; 5: 255-261.
38. Robak J, Gryglewski R. Flavonoids are scavengers of superoxide anions. Biochem Phamacol 1988; 37: 837-841.
39. Seo HJ, Kim SJ, Do GM, Choi MS. Quercetin supplement is beneficial for altering lipid metabolism and antioxidant enzyme activities in the middle of ethanol feeding in rats. Nutr Sci. 2006; 9: 259-266.
40. Steinberg D. The rediscovery of high density lipoprotein: a negative risk factor in atherosclerosis. Eur J Clin Invest 1978; 8: 107-109.
41. The American Institute of Nutrition: Report of American Institue of Nutrition Ad Hoc ommittee on Standards for Nutritional Studies. J Nutr 1977; 107:1340-1348.
42. 14C] quercetin in the ACI rat. Japan J Exp Med 1983; 53: 41-50.
43. Yugarani T, Tan BKH, Teh M, Das NP. Effects of polyphenolic natural products on the lipid profiles of rats fed high fat diets. Lipids 1992; 27: 181-186.
44. Korean Source
45. Korean Source
46. Korean Source