Mammalian target of rapamycin complex 1 signaling opposes the effects of anchorage loss, leading to activation of Cdk4 and Cdc6 stabilization

FEBS Letters

Volumn 584, Issue 13, 2010, Pages 2779-2785

  Arakawa Takeuchi, Shiho ^a   Kobayashi, Kohei ^a   Park, Jung Ha ^a   Uranbileg, Baasanjav ^a   Yamamoto, Hanako ^a   Jinno, Shigeki ^a   Okayama, Hiroto ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Anchorage; APC CCdh1; Cdc6; Cdk4; Eker; Emi1; Mammalian target of rapamycin complex 1; Rheb

Indexed keywords

CELL CYCLE PROTEIN 6; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 6; EARLY MITOTIC INHIBITOR 1 PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; REGULATOR PROTEIN; RHEB PROTEIN; TUBERIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ANCHORAGE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; FIBROBLAST; GENE MUTATION; GENE OVEREXPRESSION; MUTANT; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CASPASE 3; CELL CYCLE PROTEINS; CELL LINE; CHROMOSOMAL PROTEINS, NON-HISTONE; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE 6; IMMUNOBLOTTING; PROTEIN STABILITY; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; UBIQUITINATION;

MAMMALIA; RATTUS;

EID: 77953718210     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.05.005     Document Type: Article

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