High prevalence of plasmid-mediated 16S rRNA methylase gene rmtB among Escherichia coli clinical isolates from a Chinese teaching hospital

BMC Infectious Diseases

Volumn 10, Issue , 2010, Pages

  Yu, Fang you ^a   Yao, Dan ^b   Pan, Jing ye ^b   Chen, Chong ^b   Qin, Zhi qiang ^c   Parsons, Chris ^c   Yang, Le he ^b   Li, Qiao qiao ^b   Zhang, Xue qing ^b   Qu, Di ^a   Wang, Liang xing ^b  

^a FUDAN UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; ARMA PROTEIN; EXTENDED SPECTRUM BETA LACTAMASE; GENTAMICIN; METHYLTRANSFERASE; RMTB PROTEIN; RNA 16S; TNPD PROTEIN; TNPU PROTEIN; TOBRAMYCIN; TRANSPOSASE; UNCLASSIFIED DRUG; AMINOGLYCOSIDE; ANTIINFECTIVE AGENT; BACTERIAL DNA; BETA LACTAMASE; ESCHERICHIA COLI PROTEIN; RMTB PROTEIN, E COLI; RRNA (ADENOSINE O 2' )METHYLTRANSFERASE; RRNA (ADENOSINE-O-2'-)METHYLTRANSFERASE;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENETICS; BACTERIUM CULTURE; BACTERIUM ISOLATION; CHINA; CONTROLLED STUDY; DNA FLANKING REGION; DNA SEQUENCE; ENZYME ANALYSIS; ESCHERICHIA COLI; FLUORESCENCE IN SITU HYBRIDIZATION; GENE IDENTIFICATION; GENE LOCUS; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; PULSED FIELD GEL ELECTROPHORESIS; SEQUENCE HOMOLOGY; TEACHING HOSPITAL; TRANSPOSON; BACTERIUM CONJUGATION; BACTERIUM IDENTIFICATION; CHEMISTRY; CLUSTER ANALYSIS; DNA FINGERPRINTING; ENZYMOLOGY; ESCHERICHIA COLI INFECTION; GENETICS; HORIZONTAL GENE TRANSFER; HUMAN; IN SITU HYBRIDIZATION; ISOLATION AND PURIFICATION; MICROBIOLOGY; PREVALENCE;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BACTERIAL TYPING TECHNIQUES; BETA-LACTAMASES; CHINA; CLUSTER ANALYSIS; CONJUGATION, GENETIC; DNA FINGERPRINTING; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI PROTEINS; GENE TRANSFER, HORIZONTAL; HOSPITALS, TEACHING; HUMANS; IN SITU HYBRIDIZATION; METHYLTRANSFERASES; PLASMIDS; POLYMERASE CHAIN REACTION; PREVALENCE; SEQUENCE ANALYSIS, DNA;

EID: 77953704007     PISSN: None     EISSN: 14712334     Source Type: Journal    
DOI: 10.1186/1471-2334-10-184     Document Type: Article

References (30)

1. Yamane K, Wachino J, Doi Y, Kurokawa H, Arakawa Y. Global spread of multiple aminoglycoside resistance genes. Emerg Infect Dis 2005, 11(6):951-953.
2. Doi Y, Arakawa Y. 16S ribosomal RNA methylation: emerging resistance mechanism against aminoglycosides. Clin Infect Dis 2007, 45(1):88-94. 10.1086/518605, 17554708.
3. Kotra LP, Haddad J, Mobashery S. Aminoglycosides: perspectives on mechanisms of action and resistance and strategies to counter resistance. Antimicrob Agents Chemother 2000, 44(12):3249-3256. 10.1128/AAC.44.12.3249-3256.2000, 90188, 11083623.
4. Galimand M, Courvalin P, Lambert T. Plasmid-mediated high-level resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylation. Antimicrob Agents Chemother 2003, 47(8):2565-2571. 10.1128/AAC.47.8.2565-2571.2003, 166065, 12878520.
5. Yan JJ, Wu JJ, Ko WC, Tsai SH, Chuang CL, Wu HM, Lu YJ, Li JD. Plasmid-mediated 16S rRNA methylases conferring high-level aminoglycoside resistance in Escherichia coli and Klebsiella pneumoniae isolates from two Taiwanese hospitals. J Antimicrob Chemother 2004, 54(6):1007-1012. 10.1093/jac/dkh455, 15486082.
6. Doi Y, Yokoyama K, Yamane K, Wachino J, Shibata N, Yagi T, Shibayama K, Kato H, Arakawa Y. Plasmid-mediated 16S rRNA methylase in Serratia marcescens conferring high-level resistance to aminoglycosides. Antimicrob Agents Chemother 2004, 48(2):491-496. 10.1128/AAC.48.2.491-496.2004, 321553, 14742200.
7. Yokoyama K, Doi Y, Yamane K, Kurokawa H, Shibata N, Shibayama K, Yagi T, Kato H, Arakawa Y. Acquisition of 16S rRNA methylase gene in Pseudomonas aeruginosa. Lancet 2003, 362(9399):1888-1893. 10.1016/S0140-6736(03)14959-8, 14667745.
8. Wachino J, Yamane K, Shibayama K, Kurokawa H, Shibata N, Suzuki S, Doi Y, Kimura K, Ike Y, Arakawa Y. Novel plasmid-mediated 16S rRNA methylase, RmtC, found in a proteus mirabilis isolate demonstrating extraordinary high-level resistance against various aminoglycosides. Antimicrob Agents Chemother 2006, 50(1):178-184. 10.1128/AAC.50.1.178-184.2006, 1346777, 16377684.
9. Doi Y, de Oliveira Garcia D, Adams J, Paterson DL. Coproduction of novel 16S rRNA methylase RmtD and metallo-beta-lactamase SPM-1 in a panresistant Pseudomonas aeruginosa isolate from Brazil. Antimicrob Agents Chemother 2007, 51(3):852-856. 10.1128/AAC.01345-06, 1803107, 17158944.
10. Wachino J, Shibayama K, Kurokawa H, Kimura K, Yamane K, Suzuki S, Shibata N, Ike Y, Arakawa Y. Novel plasmid-mediated 16S rRNA m1A1408 methyltransferase, NpmA, found in a clinically isolated Escherichia coli strain resistant to structurally diverse aminoglycosides. Antimicrob Agents Chemother 2007, 51(12):4401-4409. 10.1128/AAC.00926-07, 2168023, 17875999.
11. Tan TY, Ng LS, He J, Hsu LY. CTX-M and ampC beta-lactamases contributing to increased prevalence of ceftriaxone-resistant Escherichia coli in Changi General Hospital, Singapore. Diagn Microbiol Infect Dis 2009,
12. Liu JH, Deng YT, Zeng ZL, Gao JH, Chen L, Arakawa Y, Chen ZL. Coprevalence of plasmid-mediated quinolone resistance determinants QepA, Qnr, and AAC(6')-Ib-cr among 16S rRNA methylase RmtB-producing Escherichia coli isolates from pigs. Antimicrob Agents Chemother 2008, 52(8):2992-2993. 10.1128/AAC.01686-07, 2493129, 18490500.
13. Du XD, Wu CM, Liu HB, Li XS, Beier RC, Xiao F, Qin SS, Huang SY, Shen JZ. Plasmid-mediated ArmA and RmtB 16S rRNA methylases in Escherichia coli isolated from chickens. J Antimicrob Chemother 2009, 64(6):1328-1330. 10.1093/jac/dkp354, 19808234.
14. Wu Q, Zhang Y, Han L, Sun J, Ni Y. Plasmid-mediated 16S rRNA methylases in aminoglycoside-resistant Enterobacteriaceae isolates in Shanghai, China. Antimicrob Agents Chemother 2009, 53(1):271-272. 10.1128/AAC.00748-08, 2612184, 18955532.
15. Institute CaLS Performance standards for antimicrobial susceptibility testing, 18th informational supplement (M100-S18). 2008, Clinical and Laboratory Standards Institute, Wayne, PA, USA, Institute CaLS.
16. Wang M, Tran JH, Jacoby GA, Zhang Y, Wang F, Hooper DC. Plasmid-mediated quinolone resistance in clinical isolates of Escherichia coli from Shanghai, China. Antimicrob Agents Chemother 2003, 47(7):2242-2248. 10.1128/AAC.47.7.2242-2248.2003, 161834, 12821475.
17. Yu F, Wang L, Pan J, Yao D, Chen C, Zhu T, Lou Q, Hu J, Wu Y, Zhang X, et al. Prevalence of 16S rRNA methylase genes in Klebsiella pneumoniae isolates from a Chinese teaching hospital: coexistence of rmtB and armA genes in the same isolate. Diagn Microbiol Infect Dis 2009, 64(1):57-63. 10.1016/j.diagmicrobio.2009.01.020, 19232867.
18. Yu Y, Ji S, Chen Y, Zhou W, Wei Z, Li L, Ma Y. Resistance of strains producing extended-spectrum beta-lactamases and genotype distribution in China. J Infect 2007, 54(1):53-57. 10.1016/j.jinf.2006.01.014, 16533535.
19. Wang M, Sahm DF, Jacoby GA, Hooper DC. Emerging plasmid-mediated quinolone resistance associated with the qnr gene in Klebsiella pneumoniae clinical isolates in the United States. Antimicrob Agents Chemother 2004, 48(4):1295-1299. 10.1128/AAC.48.4.1295-1299.2004, 375335, 15047532.
20. Carattoli A, Bertini A, Villa L, Falbo V, Hopkins KL, Threlfall EJ. Identification of plasmids by PCR-based replicon typing. J Microbiol Methods 2005, 63(3):219-228. 10.1016/j.mimet.2005.03.018, 15935499.
21. Tenover FC, Arbeit RD, Goering RV, Mickelsen PA, Murray BE, Persing DH, Swaminathan B. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbiol 1995, 33(9):2233-2239. 228385, 7494007.
22. Bogaerts P, Galimand M, Bauraing C, Deplano A, Vanhoof R, De Mendonca R, Rodriguez-Villalobos H, Struelens M, Glupczynski Y. Emergence of ArmA and RmtB aminoglycoside resistance 16S rRNA methylases in Belgium. J Antimicrob Chemother 2007, 59(3):459-464. 10.1093/jac/dkl527, 17224412.
23. Kang HY, Kim KY, Kim J, Lee JC, Lee YC, Cho DT, Seol SY. Distribution of conjugative-plasmid-mediated 16S rRNA methylase genes among amikacin-resistant Enterobacteriaceae isolates collected in 1995 to 1998 and 2001 to 2006 at a university hospital in South Korea and identification of conjugative plasmids mediating dissemination of 16S rRNA methylase. J Clin Microbiol 2008, 46(2):700-706. 10.1128/JCM.01677-07, 2238143, 18094126.
24. Fritsche TR, Castanheira M, Miller GH, Jones RN, Armstrong ES. Detection of methyltransferases conferring high-level resistance to aminoglycosides in enterobacteriaceae from Europe, North America, and Latin America. Antimicrob Agents Chemother 2008, 52(5):1843-1845. 10.1128/AAC.01477-07, 2346617, 18347105.
25. Kang HY, Kim J, Seol SY, Lee YC, Lee JC, Cho DT. Characterization of conjugative plasmids carrying antibiotic resistance genes encoding 16S rRNA methylase, extended-spectrum beta-lactamase, and/or plasmid-mediated AmpC beta-lactamase. J Microbiol 2009, 47(1):68-75. 10.1007/s12275-008-0158-3, 19229493.
26. Sabtcheva S, Saga T, Kantardjiev T, Ivanova M, Ishii Y, Kaku M. Nosocomial spread of armA-mediated high-level aminoglycoside resistance in Enterobacteriaceae isolates producing CTX-M-3 beta-lactamase in a cancer hospital in Bulgaria. J Chemother 2008, 20(5):593-599.
27. Yu YS, Zhou H, Yang Q, Chen YG, Li LJ. Widespread occurrence of aminoglycoside resistance due to ArmA methylase in imipenem-resistant Acinetobacter baumannii isolates in China. J Antimicrob Chemother 2007, 60(2):454-455. 10.1093/jac/dkm208, 17561497.
28. Galimand M, Sabtcheva S, Courvalin P, Lambert T. Worldwide disseminated armA aminoglycoside resistance methylase gene is borne by composite transposon Tn1548. Antimicrob Agents Chemother 2005, 49(7):2949-2953. 10.1128/AAC.49.7.2949-2953.2005, 1168633, 15980373.
29. Yamane K, Wachino J, Suzuki S, Kimura K, Shibata N, Kato H, Shibayama K, Konda T, Arakawa Y. New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate. Antimicrob Agents Chemother 2007, 51(9):3354-3360. 10.1128/AAC.00339-07, 2043241, 17548499.
30. Perichon B, Bogaerts P, Lambert T, Frangeul L, Courvalin P, Galimand M. Sequence of conjugative plasmid pIP1206 mediating resistance to aminoglycosides by 16S rRNA methylation and to hydrophilic fluoroquinolones by efflux. Antimicrob Agents Chemother 2008, 52(7):2581-2592. 10.1128/AAC.01540-07, 2443923, 18458128.