Reticulocyte mitophagy: Monitoring mitochondrial clearance in a mammalian model

Autophagy

Volumn 6, Issue 3, 2010, Pages 405-408

  Zhang, Ji ^a   Ney, Paul A ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

Mitochondria; Mitophagy; Reticulocyte

Indexed keywords

ANIMAL CELL; ARTICLE; AUTOPHAGY; CELL MEMBRANE DEPOLARIZATION; CONFOCAL LASER MICROSCOPY; FLOW CYTOMETRY; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NONHUMAN; RETICULOCYTE;

ANIMALIA; MAMMALIA;

EID: 77953695068     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.6.3.11245     Document Type: Article

References (17)

1. Wallace DC. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu Rev Genet 2005; 39:359-407.
2. Terman A, Gustafsson B, Brunk UT. Autophagy, organelles and ageing. J Pathol 2007; 211:134-43.
3. Elmore SP, Qian T, Grissom SF, Lemasters JJ. The mitochondrial permeability transition initiates autophagy in rat hepatocytes. FASEB J 2001; 15:2286-7.
4. Twig G, Elorza A, Molina AJ, et al. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. EMBO J 2008; 27:433-46.
5. Narendra D, Tanaka A, Suen DF, Youle RJ. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 2008; 183:795-803.
6. Komatsu M, Waguri S, Ueno T, et al. Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice. J Cell Biol 2005; 169:425-34.
7. Gronowicz G, Swift H, Steck TL. Maturation of the reticulocyte in vitro. J Cell Sci 1984; 71:177-97.
8. Schweers RL, Zhang J, Randall MS, et al. NIX is required for programmed mitochondrial clearance during reticulocyte maturation. Proc Natl Acad Sci USA 2007; 104:19500-5.
9. Sandoval H, Thiagarajan P, Dasgupta SK, et al. Essential role for Nix in autophagic maturation of erythroid cells. Nature 2008; 454:232-5.
10. Zhang J, Randall MS, Loyd MR, et al. Mitochondrial clearance is regulated by Atg7-dependent and -independent mechanisms during reticulocyte maturation. Blood 2009; 114:157-64.
11. Chasis JA, Prenant M, Leung A, Mohandas N. Membrane assembly and remodeling during reticulocyte maturation. Blood 1989; 74:1112-20.
12. Koury MJ, Koury ST, Kopsombut P, Bondurant MC. In vitro maturation of nascent reticulocytes to erythrocytes. Blood 2005; 105:2168-74.
13. Mel HC, Prenant M, Mohandas N. Reticulocyte motility and form: studies on maturation and classification. Blood 1977; 49:1001-9.
14. Zhang J, Kundu M, Ney PA. Mitophagy in mammalian cells: the reticulocyte model. Methods Enzymol 2009; 452:227-45.
15. Kundu M, Lindsten T, Yang CY, et al. Ulk1 plays a critical role in the autophagic clearance of mitochondria and ribosomes during reticulocyte maturation. Blood 2008; 112:1493-502.
16. Heinrich AC, Pelanda R, Klingmuller U. A mouse model for visualization and conditional mutations in the erythroid lineage. Blood 2004; 104:659-66.
17. Goldberg B, Stern A. The mechanism of oxidative hemolysis produced by phenylhydrazine. Mol Pharmacol 1977; 13:832-9.