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Volumn 98, Issue 4, 2010, Pages 336-343

Trenbolone causes irreversible masculinization of zebrafish at environmentally relevant concentrations

Author keywords

Androgens; Masculinization; Recovery; Sex ratio; Trenbolone; Zebrafish

Indexed keywords

TRENBOLONE; VITELLOGENIN;

EID: 77953687785     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2010.03.008     Document Type: Article
Times cited : (111)

References (43)
  • 2
    • 8144226890 scopus 로고    scopus 로고
    • Small fish models for identifying and assessing the effects of endocrine-disrupting chemicals
    • Ankley G.T., Johnson R.D. Small fish models for identifying and assessing the effects of endocrine-disrupting chemicals. ILAR J. 2004, 45:469-483.
    • (2004) ILAR J. , vol.45 , pp. 469-483
    • Ankley, G.T.1    Johnson, R.D.2
  • 3
    • 0034473229 scopus 로고    scopus 로고
    • Characterisation of the affinity of different anabolics and synthetic hormones to the human androgen receptor, human sex hormone binding globulin and to the bovine progestin receptor
    • Bauer E.R.S., Daxenberger A., Petri T., Sauerwein H., Meyer H.H.D. Characterisation of the affinity of different anabolics and synthetic hormones to the human androgen receptor, human sex hormone binding globulin and to the bovine progestin receptor. APMIS 2000, 108:838-846.
    • (2000) APMIS , vol.108 , pp. 838-846
    • Bauer, E.R.S.1    Daxenberger, A.2    Petri, T.3    Sauerwein, H.4    Meyer, H.H.D.5
  • 4
    • 2542420854 scopus 로고    scopus 로고
    • Impacts of 17 beta-estradiol, including environmentally relevant concentrations, on reproduction after exposure during embryo-larval-, juvenile- and adult-life stages in zebrafish (Danio rerio)
    • Brion F., Tyler C.R., Palazzi X., Laillet B., Porcher J.M., Garric J., Flammarion P. Impacts of 17 beta-estradiol, including environmentally relevant concentrations, on reproduction after exposure during embryo-larval-, juvenile- and adult-life stages in zebrafish (Danio rerio). Aquat. Toxicol. 2004, 68:193-217.
    • (2004) Aquat. Toxicol. , vol.68 , pp. 193-217
    • Brion, F.1    Tyler, C.R.2    Palazzi, X.3    Laillet, B.4    Porcher, J.M.5    Garric, J.6    Flammarion, P.7
  • 7
    • 18244367401 scopus 로고    scopus 로고
    • An environmentally relevant concentration of estrogen induces arrest of male gonad development in zebrafish, Danio rerio
    • Fenske M., Maack G., Schafers C., Segner H. An environmentally relevant concentration of estrogen induces arrest of male gonad development in zebrafish, Danio rerio. Environ. Toxicol. Chem. 2005, 24:1088-1098.
    • (2005) Environ. Toxicol. Chem. , vol.24 , pp. 1088-1098
    • Fenske, M.1    Maack, G.2    Schafers, C.3    Segner, H.4
  • 8
    • 1542375216 scopus 로고    scopus 로고
    • Aromatase modulation alters gonadal differentiation in developing zebrafish (Danio rerio)
    • Fenske M., Segner H. Aromatase modulation alters gonadal differentiation in developing zebrafish (Danio rerio). Aquat. Toxicol. 2004, 67:105-126.
    • (2004) Aquat. Toxicol. , vol.67 , pp. 105-126
    • Fenske, M.1    Segner, H.2
  • 11
    • 0141726870 scopus 로고    scopus 로고
    • Transgenic zebrafish with fluorescent germ cell: a useful tool to visualize germ cell proliferation and juvenile hermaphroditism in vivo
    • Hsiao C.D., Tsai H.J. Transgenic zebrafish with fluorescent germ cell: a useful tool to visualize germ cell proliferation and juvenile hermaphroditism in vivo. Dev. Biol. 2003, 262:313-323.
    • (2003) Dev. Biol. , vol.262 , pp. 313-323
    • Hsiao, C.D.1    Tsai, H.J.2
  • 13
    • 43749121689 scopus 로고    scopus 로고
    • Degradation of synthetic androgens 17 alpha- and 17 beta-trenbolone and trendione in agricultural soils
    • Khan B., Lee L.S., Sassman S.A. Degradation of synthetic androgens 17 alpha- and 17 beta-trenbolone and trendione in agricultural soils. Environ. Sci. Technol. 2008, 42:3570-3574.
    • (2008) Environ. Sci. Technol. , vol.42 , pp. 3570-3574
    • Khan, B.1    Lee, L.S.2    Sassman, S.A.3
  • 16
    • 0036692470 scopus 로고    scopus 로고
    • Quantitative assessment of foetal exposure to trenbolone acetate, zeranol and melengestrol acetate, following maternal dosing in rabbits
    • Lange I.G., Daxenberger A., Meyer H.H.D., Rajpert-De Meyts E., Skakkebaek N.E., Veeramachaneni D.N.R. Quantitative assessment of foetal exposure to trenbolone acetate, zeranol and melengestrol acetate, following maternal dosing in rabbits. Xenobiotica 2002, 32:641-651.
    • (2002) Xenobiotica , vol.32 , pp. 641-651
    • Lange, I.G.1    Daxenberger, A.2    Meyer, H.H.D.3    Rajpert-De Meyts, E.4    Skakkebaek, N.E.5    Veeramachaneni, D.N.R.6
  • 17
    • 69049106482 scopus 로고    scopus 로고
    • Reversibility of estrogenic sex changes in zebrafish (Danio rerio)
    • Larsen M.G., Bilberg K., Baatrup E. Reversibility of estrogenic sex changes in zebrafish (Danio rerio). Environ. Toxicol. Chem. 2009, 28:1783-1785.
    • (2009) Environ. Toxicol. Chem. , vol.28 , pp. 1783-1785
    • Larsen, M.G.1    Bilberg, K.2    Baatrup, E.3
  • 18
    • 42749097174 scopus 로고    scopus 로고
    • Male zebrafish (Danio rerio) courtship behaviour resists the feminising effects of 17[alpha]-ethinyloestradiol-morphological sexual characteristics do not
    • Larsen M.G., Hansen K.B., Henriksen P.G., Baatrup E. Male zebrafish (Danio rerio) courtship behaviour resists the feminising effects of 17[alpha]-ethinyloestradiol-morphological sexual characteristics do not. Aquat. Toxicol. 2008, 87:234-244.
    • (2008) Aquat. Toxicol. , vol.87 , pp. 234-244
    • Larsen, M.G.1    Hansen, K.B.2    Henriksen, P.G.3    Baatrup, E.4
  • 19
    • 18144372044 scopus 로고    scopus 로고
    • Review of evidence: are endocrine-disrupting chemicals in the aquatic environment impacting fish populations?
    • Mills L.J., Chichester C. Review of evidence: are endocrine-disrupting chemicals in the aquatic environment impacting fish populations?. Sci. Total Environ. 2005, 343:1-34.
    • (2005) Sci. Total Environ. , vol.343 , pp. 1-34
    • Mills, L.J.1    Chichester, C.2
  • 20
    • 8844248618 scopus 로고    scopus 로고
    • Life-stage-dependent sensitivity of zebrafish (Danio rerio) to estrogen exposure
    • Maack G., Segner H. Life-stage-dependent sensitivity of zebrafish (Danio rerio) to estrogen exposure. Comp. Biochem. Physiol. C: Toxicol. Pharmacol. 2004, 139:47-55.
    • (2004) Comp. Biochem. Physiol. C: Toxicol. Pharmacol. , vol.139 , pp. 47-55
    • Maack, G.1    Segner, H.2
  • 23
    • 0142106401 scopus 로고    scopus 로고
    • Gonad development and vitellogenin production in zebrafish (Danio rerio) exposed to ethinylestradiol and methyltestosterone
    • Orn S., Holbech H., Madsen T.H., Norrgren L., Petersen G.I. Gonad development and vitellogenin production in zebrafish (Danio rerio) exposed to ethinylestradiol and methyltestosterone. Aquat. Toxicol. 2003, 65:397-411.
    • (2003) Aquat. Toxicol. , vol.65 , pp. 397-411
    • Orn, S.1    Holbech, H.2    Madsen, T.H.3    Norrgren, L.4    Petersen, G.I.5
  • 24
    • 33745280627 scopus 로고    scopus 로고
    • Comparison of vitellogenin induction, sex ratio, and gonad morphology between zebrafish and Japanese medaka after exposure to 17 alpha-ethinylestradiol and 17 beta-trenbolone
    • Orn S., Yamani S., Norrgren L. Comparison of vitellogenin induction, sex ratio, and gonad morphology between zebrafish and Japanese medaka after exposure to 17 alpha-ethinylestradiol and 17 beta-trenbolone. Arch. Environ. Contam. Toxicol. 2006, 51:237-243.
    • (2006) Arch. Environ. Contam. Toxicol. , vol.51 , pp. 237-243
    • Orn, S.1    Yamani, S.2    Norrgren, L.3
  • 25
    • 0019465522 scopus 로고
    • Differences in the biotransformation of a 17-beta-hydroxylated steroid, trenbolone acetate, in rat and cow
    • Pottier J., Cousty C., Heitzman R.J., Reynolds I.P. Differences in the biotransformation of a 17-beta-hydroxylated steroid, trenbolone acetate, in rat and cow. Xenobiotica 1981, 11:489-500.
    • (1981) Xenobiotica , vol.11 , pp. 489-500
    • Pottier, J.1    Cousty, C.2    Heitzman, R.J.3    Reynolds, I.P.4
  • 27
    • 38149142726 scopus 로고    scopus 로고
    • Xenogenesis in teleost fish through generation of germ-line chimeras by single primordial germ cell transplantation
    • Saito T., Goto-Kazeto R., Arai K., Yamaha E. Xenogenesis in teleost fish through generation of germ-line chimeras by single primordial germ cell transplantation. Biol. Reprod. 2008, 78:159-166.
    • (2008) Biol. Reprod. , vol.78 , pp. 159-166
    • Saito, T.1    Goto-Kazeto, R.2    Arai, K.3    Yamaha, E.4
  • 28
    • 34347393939 scopus 로고    scopus 로고
    • Concentration- and time-dependent effects of the synthetic estrogen, 17 alpha-ethinylestradiol, on reproductive capabilities of the zebrafish, Danio rerio
    • Schafers C., Teigeler M., Wenzel A., Maack G., Fenske M., Segner H. Concentration- and time-dependent effects of the synthetic estrogen, 17 alpha-ethinylestradiol, on reproductive capabilities of the zebrafish, Danio rerio. J. Toxicol. Environ. Health A: Curr. Issues 2007, 70:768-779.
    • (2007) J. Toxicol. Environ. Health A: Curr. Issues , vol.70 , pp. 768-779
    • Schafers, C.1    Teigeler, M.2    Wenzel, A.3    Maack, G.4    Fenske, M.5    Segner, H.6
  • 29
    • 0035195039 scopus 로고    scopus 로고
    • The fate of trenbolone acetate and melengestrol acetate after application as growth promoters in cattle: environmental studies
    • Schiffer B., Daxenberger A., Meyer K., Meyer H.H.D. The fate of trenbolone acetate and melengestrol acetate after application as growth promoters in cattle: environmental studies. Environ. Health Perspect. 2001, 109:1145-1151.
    • (2001) Environ. Health Perspect. , vol.109 , pp. 1145-1151
    • Schiffer, B.1    Daxenberger, A.2    Meyer, K.3    Meyer, H.H.D.4
  • 30
    • 67349253527 scopus 로고    scopus 로고
    • The endocrine activity of beef cattle wastes: do growth-promoting steroids make a difference?
    • Sellin M.K., Snow D.D., Gustafson S.T., Erickson G.E., Kolok A.S. The endocrine activity of beef cattle wastes: do growth-promoting steroids make a difference?. Aquat. Toxicol. 2009, 92:221-227.
    • (2009) Aquat. Toxicol. , vol.92 , pp. 221-227
    • Sellin, M.K.1    Snow, D.D.2    Gustafson, S.T.3    Erickson, G.E.4    Kolok, A.S.5
  • 31
    • 84993891062 scopus 로고
    • Stages of oocyte development in the zebrafish, Brachydanio-Rerio
    • Selman K., Wallace R.A., Sarka A., Qi X.P. Stages of oocyte development in the zebrafish, Brachydanio-Rerio. J. Morphol. 1993, 218:203-224.
    • (1993) J. Morphol. , vol.218 , pp. 203-224
    • Selman, K.1    Wallace, R.A.2    Sarka, A.3    Qi, X.P.4
  • 32
    • 56449098100 scopus 로고    scopus 로고
    • Germ line control of female sex determination in zebrafish
    • Siegfried K.R., Nusslein-Volhard C. Germ line control of female sex determination in zebrafish. Dev. Biol. 2008, 324:277-287.
    • (2008) Dev. Biol. , vol.324 , pp. 277-287
    • Siegfried, K.R.1    Nusslein-Volhard, C.2
  • 33
    • 15244338743 scopus 로고    scopus 로고
    • Development without germ cells: the role of the germ line in zebrafish sex differentiation
    • Slanchev K., Stebler J., de la Cueva-Mendez G., Raz E. Development without germ cells: the role of the germ line in zebrafish sex differentiation. Proc. Natl. Acad. Sci. U.S.A. 2005, 102:4074-4079.
    • (2005) Proc. Natl. Acad. Sci. U.S.A. , vol.102 , pp. 4074-4079
    • Slanchev, K.1    Stebler, J.2    de la Cueva-Mendez, G.3    Raz, E.4
  • 35
    • 38349002576 scopus 로고    scopus 로고
    • The behaviour and ecology of the zebrafish, Danio rerio
    • Spence R., Gerlach G., Lawrence C., Smith C. The behaviour and ecology of the zebrafish, Danio rerio. Biol. Rev. 2008, 83:13-34.
    • (2008) Biol. Rev. , vol.83 , pp. 13-34
    • Spence, R.1    Gerlach, G.2    Lawrence, C.3    Smith, C.4
  • 36
    • 0035213054 scopus 로고    scopus 로고
    • Meiotic chromosomes and stages of sex chromosome evolution in fish: zebrafish, platyfish and guppy
    • Traut W., Winking H. Meiotic chromosomes and stages of sex chromosome evolution in fish: zebrafish, platyfish and guppy. Chromosome Res. 2001, 9:659-672.
    • (2001) Chromosome Res. , vol.9 , pp. 659-672
    • Traut, W.1    Winking, H.2
  • 37
    • 0037941097 scopus 로고    scopus 로고
    • Effects of 17 alpha-ethynylestradiol in a partial life-cycle test with zebrafish (Danio rerio): effects on growth, gonads and female reproductive success
    • Van den Belt K., Verheyen R., Witters H. Effects of 17 alpha-ethynylestradiol in a partial life-cycle test with zebrafish (Danio rerio): effects on growth, gonads and female reproductive success. Sci. Total Environ. 2003, 309:127-137.
    • (2003) Sci. Total Environ. , vol.309 , pp. 127-137
    • Van den Belt, K.1    Verheyen, R.2    Witters, H.3
  • 38
    • 27944438485 scopus 로고    scopus 로고
    • Zebrafish sex determination and differentiation: involvement of FTZ-F1 genes
    • von Hofsten J., Olsson P.E. Zebrafish sex determination and differentiation: involvement of FTZ-F1 genes. Reprod. Biol. Endocrinol. 2005, 3.
    • (2005) Reprod. Biol. Endocrinol. , pp. 3
    • von Hofsten, J.1    Olsson, P.E.2
  • 39
    • 0037301084 scopus 로고    scopus 로고
    • Synaptonemal complex karyotype of zebrafish
    • Wallace B.M.N., Wallace H. Synaptonemal complex karyotype of zebrafish. Heredity 2003, 90:136-140.
    • (2003) Heredity , vol.90 , pp. 136-140
    • Wallace, B.M.N.1    Wallace, H.2
  • 40
    • 0036906417 scopus 로고    scopus 로고
    • In vitro and in vivo effects of 17 beta-trenbolone: a feedlot effluent contaminant
    • Wilson V.S., Lambright C., Ostby J., Gray L.E. In vitro and in vivo effects of 17 beta-trenbolone: a feedlot effluent contaminant. Toxicol. Sci. 2002, 70:202-211.
    • (2002) Toxicol. Sci. , vol.70 , pp. 202-211
    • Wilson, V.S.1    Lambright, C.2    Ostby, J.3    Gray, L.E.4
  • 41
    • 70350729221 scopus 로고    scopus 로고
    • Anabolic and androgenic effect of steroid trenbolone acetate on guppy (Poecilia reticulata)
    • Zamora H.S., Hernandez A.A., Herrera S.M., Pena E.M. Anabolic and androgenic effect of steroid trenbolone acetate on guppy (Poecilia reticulata). Vet. Mex. 2008, 39:269-277.
    • (2008) Vet. Mex. , vol.39 , pp. 269-277
    • Zamora, H.S.1    Hernandez, A.A.2    Herrera, S.M.3    Pena, E.M.4
  • 42
    • 57649118742 scopus 로고    scopus 로고
    • Time-dependent transcriptional profiles of genes of the hypothalamic-pituitary-gonadal axis in medaka (Oryzias latipes) exposed to fadrozole and 17 beta-trenbolone
    • Zhang X.W., Hecker M., Park J.W., Tompsett A.R., Jones P.D., Newsted J., Au D.W.T., Kong R., Wu R.S.S., Giesy J.P. Time-dependent transcriptional profiles of genes of the hypothalamic-pituitary-gonadal axis in medaka (Oryzias latipes) exposed to fadrozole and 17 beta-trenbolone. Environ. Toxicol. Chem. 2008, 27:2504-2511.
    • (2008) Environ. Toxicol. Chem. , vol.27 , pp. 2504-2511
    • Zhang, X.W.1    Hecker, M.2    Park, J.W.3    Tompsett, A.R.4    Jones, P.D.5    Newsted, J.6    Au, D.W.T.7    Kong, R.8    Wu, R.S.S.9    Giesy, J.P.10
  • 43
    • 0038322414 scopus 로고    scopus 로고
    • USDA, USDA:APHIS:VS, CEAH, National Animal Health Monitoring System, Fort Collins, CO, #N327.0500
    • USDA Part I: Baseline Reference of Feedlot Management Practices, 1999 2000, USDA:APHIS:VS, CEAH, National Animal Health Monitoring System, Fort Collins, CO, #N327.0500. http://nahms.aphis.usda.gov/feedlot/feedlot99/FD99Pt1.pdf.
    • (2000) Part I: Baseline Reference of Feedlot Management Practices, 1999


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