The endocrine activity of beef cattle wastes: Do growth-promoting steroids make a difference?

Aquatic Toxicology

Volumn 92, Issue 4, 2009, Pages 221-227

  Sellin, Marlo K ^a   Snow, Daniel D ^c   Gustafson, Sarah T ^b   Erickson, Galen E ^d   Kolok, Alan S ^a,b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF NEBRASKA AT OMAHA   (United States)

^c UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^d UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

17 Estradiol; Fathead minnow; Growth promoting cattle implants; Hepatic vitellogenin gene expression; Trenbolone acetate

Indexed keywords

ESTRADIOL; GROWTH PROMOTOR; STEROID; TRENBOLONE ACETATE; VITELLOGENIN;

CATTLE; COMPARATIVE STUDY; CONCENTRATION (COMPOSITION); CYPRINID; ENDOCRINE DISRUPTOR; ENDOCRINE SYSTEM; ESTROGENIC COMPOUND; FECAL PELLET; FEMINIZATION; GENE EXPRESSION; GROWTH REGULATOR; RNA; STEROID; URINE;

ANIMAL EXPERIMENT; ARTICLE; BEEF CATTLE; BULLOCK; ENDOCRINE FUNCTION; EXPOSURE; FECES; GENE EXPRESSION; MALE; NONHUMAN; PIMEPHALES PROMELAS; PRIORITY JOURNAL; SEX DIFFERENCE; URINE; WASTE;

ANABOLIC AGENTS; ANIMALS; CATTLE; CYPRINIDAE; DRUG IMPLANTS; ESTRADIOL; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION; LIVER; MALE; MANURE; TRENBOLONE; VITELLOGENINS; WASTE PRODUCTS; WATER POLLUTANTS, CHEMICAL;

BOS; PIMEPHALES PROMELAS;

EID: 67349253527     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.aquatox.2009.02.004     Document Type: Article

References (39)

1. Ankely G.T., Jensen K.M., Makynen E.A., Kahl M.D., Korte J.J., Hornung M.W., Henry T.R., Denny J.S., Leino R.L., Wilson V.S., Cardon M.C., Hartig P.C., and Gray L.E. Effects of the androgenic growth promoter 17β-trenbolone on fecundity and reproductive endocrinology of the fathead minnow. Environ. Toxicol. Chem. 22 (2003) 1350-1360
2. Ankley G.T., Defoe D.L., Kahl M.D., Jensen K.M., Makynen E.A., Miracle A., Hartig P., Gray L.E., Cardon M., and Wilson. Evaluation of the model anti-androgen fluatamide for assessing the mechanistic basis of responses to an androgen in the fathead minnow (Pimephales promelas). Environ. Sci. Technol. 38 (2004) 6322-6327
3. Arukwe A., Kullman S.W., and Hinton D.E. Differential biomarker gene and protein expressions in nonylphenol and estradiol-17β treated juvenile rainbow trout (Oncorhynchus mykiss). Comp. Biochem. Physiol. 129C (2001) 1-10
4. Balch G.C., Shami K., Wilson P.J., Wakamatsu Y., and Metcalfe C.D. Feminization of female leukophore-free strain of Japanese medaka (Oryzias latipes) exposed to 17β-estradiol. Environ. Toxicol. Chem. 23 (2004) 2763-2768
5. Belfroid A.C., Van der Horst A., Vathaak A.D., Schafer A.J., Rijs G.B.J., Wegener J., and Cofino W.P. Analysis and occurrence of estrogenic hormones and their glucuronides in surface water and waste water in The Netherlands. Sci. Total Environ. 225 (1999) 101-108
6. Brion F., Tyler C.R., Palazzi X., Laillet B., Porcher J.M., Garric J., and Flammarion P. Impacts of 17β-estradiol, including environmentally relevant concentrations, on reproduction after exposure during embryo-larval-, juvenile- and adult-life stages in zebrafish (Danio rerio). Aquat. Toxicol. 68 (2004) 193-217
7. Carpenter S.R., Caraco N.F., Correll D.L., Howarth R.W., Sharpley A.N., and Smith V.H. Nonpoint pollution of surface waters with phosphorus and nitrogen. Ecol. Appl. 8 (1998) 559-568
8. D'Ascenzo G., DiCorcia A., Gentili A., Mancini R., Mastropasqua R., Nazzari M., and Samperi R. Fate of natural estrogen conjugates in municipal sewage transport and treatment facilities. Sci. Total Environ. 302 (2003) 199-209
9. Durhan E.J., Lambright C.S., Makynen E.A., Lazorchak J., Hartig P.C., Wilson V.S., Gray L.E., and Ankley G.T. Identification of metabolites of trenbolone acetate in androgenic runoff from a beef feedlot. Environ. Health Perspect. 114 Suppl. 1 (2006) 65-68
10. Hartley W.R., Thiyagarajah A., Anderson M.B., Broxson M.W., Major S.E., and Zell S.I. Gonadal development in Japanese medaka (Oryzias latipes) exposed to 17β-estradiol. Mar. Environ. Res. 46 (1998) 145-148
11. Hornung M.W., Jensen K.M., Korte J.J., Kahl M.D., Durhan E.J., Denny J.S., Henry T.R., and Ankley G.T. Mechanistic basis for estrogenic effects in fathead minnow (Pimephales promelas) following exposure to the androgen 17α-methyltestosterone: conversion of 17α-methyltestosterone to 17α-methylestradiol. Aquat. Toxicol. 66 (2004) 15-23
12. Hunt D.W., Henricks D.M., Skelley G.C., and Grimes L.W. Use of trenbolone acetate and estradiol in intact and castrate male cattle: effects on growth, serum hormones, and carcass characteristics. J. Anim. Sci. 69 (1991) 2452-2462
13. 14C] estradiol-17β after intramuscular injection into Holstein steer calves. J. Anim. Sci. 62 (1986) 681-690
14. Jensen K.M., Makynen E.A., Kahl M.D., and Ankley G.T. Effects of the feedlot contaminant 17α-trenbolone on reproductive endocrinology of the fathead minnow. Environ. Sci. Technol. 40 (2006) 3112-3117
15. Klaper R., Carter B.J., Richter C.A., Drevnick P.E., Sandheinrich M.B., and Tillitt D.E. Use of a 15k gene microarray to determine gene expression changes in response to acute and chronic methylmercury exposure in the fathead minnow Pimephales promelas Rafinesque. J. Fish Biol. 72 (2008) 2207-2280
16. Kramer V.J., Miles-Richardson S., Pierens S.L., and Giesy J.P. Reproductive impairment and induction of alkaline-labile phosphatase, a biomarker of estrogen exposure, in fathead minnows (Pimephales promelas) exposed to waterborne 17β-estradiol. Aquat. Toxicol. 40 (1998) 335-360
17. Kolok A.S., Snow D.D., Kohno S., Sellin M.K., and Guillette L.J. Occurrence and biological effect of exogenous steroids in the Elkhorn River, Nebraska. Sci. Total Environ. 388 (2007) 104-115
18. Kolok A.S., and Sellin M.K. The environmental impact of growth-promoting compounds employed by the beef cattle industry: history, current knowledge and future directions. Rev. Environ. Contam. Toxicol. 195 (2008) 1-30
19. Larkin P., Sabo-Attwood T., Kelso J., and Denslow N.D. Gene expression analysis of largemouth bass exposed to estradiol, nonylphenol, and p,p′-DDE. Comp. Biochem. Physiol. 133B (2002) 543-557
20. Lee C.Y., Henricks D.M., Skelley G.C., and Grimes L.W. Growth and hormonal response of intact and castrate male cattle to trenbolone acetate and estradiol. J. Anim. Sci. 68 (1990) 2682-2889
21. Lorenzen A., Hendel J.G., Conn K.L., Bittman S., Kwabiah A.B., Lazarovitz G., Masse D., McAllister T.A., and Topp E. Survey of hormone activities in municipal biosolids and animal manures. Environ. Toxicol. 19 (2004) 216-225
22. Miles-Richardson S.R., Kramer V.J., Fitzgerald S.D., Render J.A., Yamini B., Barbee S.J., and Giesy J.P. Effects of waterborne exposures of 17β-estradiol on secondary sex characteristics and gonads of fathead minnows (Pimephales promelas). Aquat. Toxciol. 47 (1999) 129-145
23. Miracle A., Ankley G., and Lattier D. Expression of two vitellogenin genes (vg1 and vg3) in fathead minnow (Pimephales promelas) liver in response to exposure to steroidal estrogens and androgens. Ecotoxicol. Environ. Saf. 63 (2006) 337-342
24. Moens L.N., van der Ven K., Van Remortel P., Del-Favero J., and De Coen W.M. Expression profiling of endocrine-disrupting compounds using a customized Cyprinus carpio cDNA microarray. Toxicol. Sci. 93 (2006) 298-310
25. Montgomery T.H., Dw P.F., and Brown M.S. Optimizing carcass value and the use of anabolic implants in beef cattle. J. Anim. Sci. 79 (2001) E296-E306
26. Orlando E.F., Kolok A.S., Binzcik G., Gates J., Horton M.K., Lambright C., Gray L.E., and Guillette L.J. Endocrine disrupting effects of cattle feedlot effluent on an aquatic sentinel species, the fathead minnow. Environ. Health Perspect. 112 (2004) 353-358
27. Orn S., Yamani S., and Norrgren L. Comparison of vitellogenin induction, sex ratio, and gonad morphology between zebrafish and Japanese medaka after exposure to 17α-ethinylestradiol and 17β-trenbolone. Arch. Environ. Contam. Toxicol. 51 (2006) 237-243
28. Peake E.B., Locke J.C., Tierney L.L., and Kolok A.S. Copper tolerance in fathead minnows: II. Maternal transfer. Environ. Toxicol. Chem. 23 (2004) 208-211
29. Pottier J., Cousty C., Heitzman R.J., and Reynolds P. Differences in the biotransformation of a 17β-hydroxylated steroid, trenbolone acetate in rat and cow. Xenobiotica 11 (1981) 489-500
30. Raloff J. Hormones: here's the beef. Sci. News 161 (2002) 10-12
31. Randall D.J., and Tsui T.K.N. Ammonia toxicity in fish. Mar. Pollut. Bull. 45 (2002) 17-23
32. Rodriguez-Mozaz S., Lopez de Alda M.J., and Barcelo D. Picogram per liter level determination of estrogens in natural waters and waterworks by a fully automated on-line solid-phase extraction-liquid chromatography-electrospray tandem mass spectrometry method. Anal. Chem. 76 (2004) 6998-7006
33. Rouse J.D., Bishop C.A., and Struger J. Nitrogen pollution: an assessment of its threat to amphibian survival. Environ. Health Perspect. 107 (1999) 799-803
34. Schiffer B., Daxenberger A., Meyer K., and Meyer H.H.D. The fate of trenbolone acetate and melengestrol acetate after application as growth promoters in cattle: environmental studies. Environ. Health Perspect. 109 (2001) 1145-1151
35. Seki M., Fujishima S., Nozaka T., Maeda M., and Kobayashi K. Comparison of response to 17β-trenbolone among three small fish species. Environ. Toxicol. Chem. 25 (2006) 2742-2752
36. Sellin M.K., Snow D.D., Akerly D.L., and Kolok A.S. Estrogenic compounds downstream of three small cities in eastern Nebraska: occurrence and biological effect. J. Am. Water Resour. Assoc. 45 (2009) 1-8
37. Siemens M.G. Tools for Optimizing Feedlot Production (1996), University of Wisconsin, Cooperative Extension, Madison, WI 8 pp. (publication #A366)
38. Sone Z., Hinage M., Itamoto M., Katsu Y., Watanabe H., Urushitani H., Tooi O., Guillette Jr. L.J., and Iguchi T. Effects of an androgenic growth promoter 17β-trenbolone on masculinization of mosquitofish (Gambusia affinis affinis). Gen. Comp. Endocrinol. 143 (2005) 151-160
39. Soto A.M., Calabro J.M., Prechtl N.V., Yau A.Y., Orlando E.F., Daxenberger A., Kolok A.S., Guillette Jr. L.J., le Bizec B., Lange I.G., and Sonnenschein C. Androgenic and estrogenic activity in cattle feeldot effluent receiving water bodies of eastern Nebraska, USA. Environ. Health Perspect. 112 (2004) 346-352