Time-dependent transcriptional profiles of genes of the hypothalamic-pituitary-gonadal axis in medaka (Oryzias latipes) exposed to fadrozole and 17β-trenbolone

Environmental Toxicology and Chemistry

Volumn 27, Issue 12, 2008, Pages 2504-2511

  Zhang, Xiaowei ^a   Hecker, Markus ^a,b,d   Park, June Woo ^a   Tompsett, Amber R ^a   Jones, Paul D ^a,d   Newsted, John ^a,c   Au, Doris W T ^e   Kong, Richard ^e   Wu, Rudolf S S ^e   Giesy, John P ^a,d,e  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b ENTRIX   (Canada)

^c ENTRIX   (United States)

^d UNIVERSITY OF SASKATCHEWAN   (Canada)

^e CITY UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Activin; Endrocrine disruption gonadal axis; Fecundity; Vitellogenin

Indexed keywords

ENZYME ACTIVITY; GENE EXPRESSION; GENES; GLYCOPROTEINS; LIVER; PLASMAS;

ACTIVIN; AROMATASE; ENDROCRINE DISRUPTION-GONADAL AXIS; ESTROGEN RECEPTORS; EXPRESSION PROFILES; FECUNDITY; HORMONE RECEPTORS; JAPANESE MEDAKA; LIPOPROTEIN RECEPTORS; MOLECULAR PATHWAYS; MOLECULAR RESPONSES; ORYZIAS LATIPES; PLASMA CONCENTRATIONS; POLYMERASE CHAIN REACTIONS; TIME REVERSES; TRANSCRIPTIONAL PROFILES; TRANSCRIPTIONAL RESPONSES; TRENBOLONE; UNDERLYING MECHANISMS; VITELLOGENIN;

TRANSCRIPTION;

ANDROGEN; AROMATASE; CHORIOGENIN; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; FADROZOLE; LOW DENSITY LIPOPROTEIN RECEPTOR; LUTEINIZING HORMONE RECEPTOR; PROTEIN DERIVATIVE; PROTEIN PRECURSOR; TESTOSTERONE; TRENBOLONE; UNCLASSIFIED DRUG; VITELLOGENIN;

ANDROGEN; BLOOD; ENDOCRINE DISRUPTOR; ENZYME ACTIVITY; FECUNDITY; GENE EXPRESSION; MOLECULAR ANALYSIS; PEPTIDE; POLLUTION EXPOSURE; POLYMERASE CHAIN REACTION; PROTEIN; REAL TIME; TELEOST;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENVIRONMENTAL EXPOSURE; ENZYME INHIBITION; ESTROGEN BLOOD LEVEL; FEMALE; FERTILITY; GENE EXPRESSION PROFILING; GENETIC TRANSCRIPTION; HORMONE INHIBITION; HORMONE RELEASE; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; LIVER; MALE; NONHUMAN; ORYZIAS; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TESTIS; TIME;

ANIMALS; AROMATASE INHIBITORS; FADROZOLE; FEMALE; GENE EXPRESSION PROFILING; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; ORYZIAS; OVARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TESTIS; TRANSCRIPTION, GENETIC; TRENBOLONE;

ORYZIAS LATIPES; ORYZIINAE;

EID: 57649118742     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1897/08-082.1     Document Type: Article

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